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Gentle Premium Powder Infant Formula - 34oz - up&up™: Gluten-Free, Kosher, Hydrolyzed Protein - 2 of 4Gentle Premium Powder Infant Formula - 34oz - up&up™: Gluten-Free, Kosher, Hydrolyzed Protein - 3 of 4Gentle Premium Powder Infant Formula - 34oz - up&up™: Gluten-Free, Kosher, Hydrolyzed Protein - 4 of 4
Gentle Premium Powder Infant Formula - 34oz - up&up™: Gluten-Free, Kosher, Hydrolyzed Protein - 1 of 4

Gentle Premium Powder Infant Formula - 34oz - up&up™: Gluten-Free, Kosher, Hydrolyzed Protein

4 Questions
$31.99 ($0.94/ounce)

In Stock

Eligible for registries and wish lists

At a glance

About this item

Highlights

  • Compare to the nutrition of Enfamil NeuroPro Gentlease
  • Easy to digest, for fussiness, gas and crying
  • Complete nutrition to support growth, brain and general development
  • Gentle Immune Blend 6 including 2'-FL HMO for immune support
  • NON-GMO, no artificial colors, flavors or growth hormones

Description

Compare to the nutrition of Enfamil Neuropro Gentlease. up&up™ Gentle Premium Infant Formula offers complete nutrition to support your baby's growth, brain and general development. For fussiness, gas and crying, this soothing formula contains Gentle Immune Blend 6 with 2’-FL HMO, Vitamin C and E, Selenium, Partially Hydrolyzed Whey Protein, Reduced Lactose (has 20 percent the lactose compared to our full lactose, routine, milk-based Infant Premium formula). Human Milk Oligosaccharide not from human milk. NON-GMO, ingredients not genetically engineered. No artificial growth hormones; no significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows. Certified Kosher by the Orthodox Union - OU-D. This product is not manufactured or distributed by the owner of trademark Enfamil Neuropro and registered trademark Gentlease.

100% Satisfaction Guaranteed.

Serving Size: 5 fl oz

Amount

Calories: 100
% Daily Value*
Protein 2.3g
Biotin 3mcg
Total Fat 5.3g
Vitamin C 12mg
Total Carbohydrate 10.8g
Choline 24mg
Water 134g
Inositol 24mg
Omega-6 (linoleic acid LA) 780mg
Calcium 82mg
Vitamin A 300iu
Phosphorus 46mg
Vitamin D 60iu
Magnesium 8mg
Vitamin E 2iu
Iron 1.8mg
Vitamin K 1mcg
Zinc 1mg
Thiamin 15mcg
Manganese 140mcg
Copper 75mcg
Riboflavin 60mcg
Iodine 15mcg
Vitamin B6 0.3mcg
Selenium 2.8mcg
Vitamin B12 1000mcg
Sodium 40mg
Niacin 16mcg
Potassium 108mg
Folic Acid 500mcg
Pantothenic Acid 63mg
Chloride 63mg
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

corn syrup, nonfat milk, palm olein, partially hydrolyzed whey, soy oil, coconut oil, high oleic (safflower or sunflower) oil, less than 2%: 2'-fucosyllactose (2'-fl), mortierella alpina oil**, schizochytrium sp. oil** l-carnitine, mixed tocopherol concentrate, monoglycerides, soy lecithin, taurine, calcium carbonate, calcium chloride, cupric sulfate, ferrous sulfate, magnesium chloride, manganese sulfate, potassium bicarbonate, potassium hydroxide, potassium iodide, potassium phosphate, sodium citrate, sodium selenite, zinc sulfate, ascorbic acid, ascorbyl palmitate, beta-carotene, biotin, calcium pantothenate, choline bitartrate, cyanocobalamin, folic acid, inositol, niacinamide, pyridoxine hydrochloride, riboflavin, thiamin hydrochloride, vitamin a palmitate, vitamin d (cholecalciferol), vitamin e (di-alpha tocopheryl acetate), vitamin k (phytonadione).

Allergens & Warnings:

WARNING: DO NOT USE MICROWAVE TO PREPARE OR WARM FORMULA. SERIOUS BURNS MAY OCCUR., CONTAINS MILK AND SOY.
Dietary Needs: Gluten-Free, Kosher
Baby Formula Focus: Easy to Digest
Base Ingredient: Hydrolyzed Protein
State of Readiness: Mix
Form: Powdered
Package Quantity: 1
Age Stage: Infant
TCIN: 87765855
UPC: 085239987643
Item Number (DPCI): 007-09-0005
Origin: Made in the USA
Grocery Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers. Any additional pictures are suggested servings only.
If the item details aren’t accurate or complete, we want to know about it.

Shipping details

Estimated ship dimensions: 5.07 inches length x 5.28 inches width x 7.4 inches height
Estimated ship weight: 2.34 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest. If purchased online with SNAP EBT, this item must be returned within 90 days of the date it was shipped, delivered by a Shipt shopper, or made ready for pickup. This 90-day return window is required by SNAP.
See the return policy for complete information.

Q: Can I put a can of this formula in a checked bag on an airplane - will the temperature affect the formula?

submitted by c0urtney - 5 months ago

  • A: Hi! Thank you for your question! Optimum storage conditions of powder product is between 50°F and 86°F in a dry environment. The powdered product can tolerate temperatures outside of the optimum storage conditions for periods of short duration of week (7 days). We recommend visiting the TSA website for more information about formula as a carry-on item.

    submitted bythe Supplier - 5 months ago
    Brand expert

Q: What is the whey and casein ratio?

submitted by Hanh - 9 months ago

  • A: Hello, thank you for your question. The Up & Up Gentle formula has a 60 whey/40 casein ratio.

    submitted bythe Supplier - 9 months ago
    Brand expert

Q: Is using warm water a requirement to prepare it, or can I prepare with room temperature water?

submitted by Marina - 10 months ago

  • A: Hello, thank you for your question. For mixing formula, the water should be warm approximately 100F (40C). This is our recommendation as it is closest to the child’s body temperature and this will also help in the reconstitution of the formula.

    submitted bythe Supplier - 10 months ago
    Brand expert

Q: Is this the same as it used to be three years ago and just difference packaging than before?

submitted by Lisa0910 - 1 year ago

  • A: Hello, thank you for your question. We are still the manufacturing of the Up & Up infant formula. This is still the Gentle formula and is compared to the nutrition of Enfamil Neuropro Gentlease. Over the years there may have been some changes to the formulation to stay comparable to Enfamil and continue to support our little ones the best we can.

    submitted bythe Supplier - 1 year ago
    Brand expert
See all questions (4)

Additional product information and recommendations

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Guests are saying

This formula offers a budget-friendly alternative to name brands, with many guests noting its effectiveness for sensitive tummies and ease of digestion. Many parents appreciate the smooth mixing and large container size, making it a practical choice for feeding. While some guests experienced issues like constipation or allergic reactions, the overall consensus highlights its affordability and comparable quality to more expensive options, making it a popular choice for many families.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.3 out of 5 stars with 558 reviews
    easy on tummy: 3.78 out of 5
    easy to prepare: 4.61 out of 5
    quality: 3.95 out of 5
    value: 4.19 out of 5
    65% would recommend
    143 recommendations
    5 out of 5 stars
    Thumbs up graphic, would recommend
    17 August, 2026Verified purchase

    Used since my child was born

    It took a couple of tries to find the right formula, after trying many, this was the one we chose. After a week, my child got used too this one, it’s affordable and meets the standards I was looking for. I looked into the ingredients and compared it with others and this definitely passed the test..
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    17 August, 2026Verified purchase

    not gentle

    not gentle on our baby girl, fussy and issues with constipation ever since we started using it. will be going back to enfamil
    1 reply from the Product Manufacturer team - 6 days ago
    We are sorry to hear about your experience with the Gentle Premium Powder Infant Formula - 34oz - up&up. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 1-800-272-5095 or via email by going to www.perrigo.com/contact-us and reference case number 2189902. We look forward to addressing your concerns and hearing from you!
    Jared
    easy on tummy: 1 out of 5
    easy to prepare: 5 out of 5
    quality: 2 out of 5
    value: 4 out of 5
    Did you find this review helpful?
    4 out of 5 stars
    Thumbs up graphic, would recommend
    14 August, 2026Verified purchase

    Good quality and reasonably priced

    Baby seems to like formula and has adjusted well.
    henrykath
    easy on tummy: 4 out of 5
    easy to prepare: 5 out of 5
    quality: 4 out of 5
    value: 4 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    13 August, 2026Verified purchase

    (no review title)

    I prefer this brand over the original name Brand
    Did you find this review helpful?
    5 out of 5 stars
    9 August, 2026Verified purchase

    (no review title)

    We love this formula
    BrookeK
    Did you find this review helpful?
    5 out of 5 stars
    7 August, 2026Verified purchase

    (no review title)

    Worth the money and the same as brand names
    Zill
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    3 August, 2026Verified purchase

    SAME AS BRAND NAME

    We switched our son over from Enfamil (Purple can) to this one back in April when he was 5 months old and he’s now 9 months. We never had any issues, so allergic reactions. I became a SAHM and buying the other brand and paying over $50 each time was just not doable anymore. We decided to give it a try and amazingly our baby boy tolerated it very well. He’s healthy and happy and I do not regret trying it and switching over. Every baby is different so if you’re debating just give it a try!
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    28 July, 2026Verified purchase

    Do not buy

    If your baby is on gentleease, and you want to switch to this formula to save money. DON'T!! it gave my baby stomach pains. Stick to what you know.
    1 reply from the Product Manufacturer team - 29 days ago
    We are sorry to hear about your experience with the Gentle Premium Powder Infant Formula - 34oz - up&up™: Gluten-Free, Kosher, Hydrolyzed Protein. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 800.272.5095 or via email by going to www.perrigo.com/contact-us and reference case number 2182558. We look forward to addressing your concerns and hearing from you!
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    19 July, 2026Verified purchase

    Better Quaility, Better Value

    Better quality then name brand. Coconut oil vs. Veg oil with Enfamil. My son doesn't do well with Enfamil. Thankful for up & up
    Angie
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    12 July, 2026Verified purchase

    (no review title)

    My baby tolerated this much better than any other brand we’ve tried. Hardly any spit up and even that was typically from eating too much. Name brands he would have larger amounts of spit up and more often. It also mixes much smoother than other brands.
    Crm
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    12 July, 2026Verified purchase

    (no review title)

    I was hesitant to switch to this from the name brand but my baby actually did better with this one! Less spit ups and better bowl movements. Wish I would have switched sooner!
    1 guest found this review helpful. Did you?
    4 out of 5 stars
    Thumbs up graphic, would recommend
    30 June, 2026Verified purchase

    Only Formula

    When my baby was born we had to use liquid ready made forma for a bit, but other than that, this is the only formula we have used. We will be saying goodbye to it in a few months, as baby will be a toddler!
    Tiffiny
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    24 June, 2026Verified purchase

    excellent product

    My baby loved it! It's easy to digest because of the hydrolyzed protein, and there's no more constipation, fussing, or crying. Thank you, Target, for offering an excellent product for a fraction of the price!
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    22 June, 2026Verified purchase

    (no review title)

    I switched to Up&Up when my baby was 2 months old and has been on it ever since. Big fans! Easy to digest, nutritional & I love how large the can is for such a great price
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    15 June, 2026Verified purchase

    Cost Effective & Super Gentle

    My 5-month-old son had severe reflux, and horrible gas and constipation after being on Neosure for 2 months post NICU stay. We switched him to Up&Up’s gentle formula with our doctor’s approval, and were so glad we did. He has thrived over these past 3 months. His weight is now in the 53rd percentile (up from being 5th percentile at birth). He also enjoys the taste, and no more excessive gas and constipation, and no reflux! It’s cost-effective and always in stock. I highly recommend it.
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    4 out of 5 stars
    Thumbs up graphic, would recommend
    27 May, 2026Verified purchase

    a good alternative to name brands formula. used for both my children

    bang for your buck
    Sid
    easy on tummy: 4 out of 5
    easy to prepare: 4 out of 5
    quality: 5 out of 5
    value: 4 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    24 May, 2026Verified purchase

    (no review title)

    I wish it could give it 0 stars. I’ve tried this 3 times hoping it would get better as he got older, but it didn’t. My baby was constipated, fussy and then had diarrhea for days. It’s nothing like enfamil, so stay away. The money saved isn’t worth it.
    1 reply from the Product Manufacturer team - 3 months ago
    We are sorry to hear about your experience with the Gentle Premium Powder Infant Formula. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 1-800-272-5095 or via email by going to www.perrigo.com/contact-us and reference case number 2164270. We look forward to addressing your concerns and hearing from you!
    Kav329
    easy on tummy: 1 out of 5
    easy to prepare: 1 out of 5
    quality: 1 out of 5
    value: 1 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    20 May, 2026Verified purchase

    (no review title)

    I combo feed and my baby does great with this formula!
    Layla
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    20 May, 2026Verified purchase

    Sensative infant formula

    My baby always drink enfamil sensitive formula and I try this one and she really like it . If your baby have a sensitive stomach this brand it's similar to enfamil .
    Bel
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    19 May, 2026Verified purchase

    Make the Switch!

    This formula is great! My baby has reflux and was on Enfamil neuropro gentle ease and switched to this because of the reviews and the price! It doesn’t bubble at all and actually sits better with my baby than the Enfamil!
    Naiomi
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?

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