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Gentle Premium Powder Infant Formula - 34oz - up&up™ - 2 of 4Gentle Premium Powder Infant Formula - 34oz - up&up™ - 3 of 4Gentle Premium Powder Infant Formula - 34oz - up&up™ - 4 of 4
Gentle Premium Powder Infant Formula - 34oz - up&up™ - 1 of 4

Gentle Premium Powder Infant Formula - 34oz - up&up™

5 Questions
$32.99 ($0.97/ounce)

In Stock

Eligible for registries and wish lists

At a glance

About this item

Highlights

  • Compare to the nutrition of Enfamil NeuroPro Gentlease
  • Easy to digest, for fussiness, gas and crying
  • Complete nutrition to support growth, brain and general development
  • Gentle Immune Blend 6 including 2'-FL HMO for immune support
  • NON-GMO, no artificial colors, flavors or growth hormones

Description

Compare to the nutrition of Enfamil Neuropro Gentlease. up&up™ Gentle Premium Infant Formula offers complete nutrition to support your baby's growth, brain and general development. For fussiness, gas and crying, this soothing formula contains Gentle Immune Blend 6 with 2’-FL HMO, Vitamin C and E, Selenium, Partially Hydrolyzed Whey Protein, Reduced Lactose (has 20 percent the lactose compared to our full lactose, routine, milk-based Infant Premium formula). Human Milk Oligosaccharide not from human milk. NON-GMO, ingredients not genetically engineered. No artificial growth hormones; no significant difference has been shown between milk derived from rbST-treated and non-rbST-treated cows. Certified Kosher by the Orthodox Union - OU-D. This product is not manufactured or distributed by the owner of trademark Enfamil Neuropro and registered trademark Gentlease.

100% Satisfaction Guaranteed.

Serving Size: 5 fl oz

Amount

Calories: 100
% Daily Value*
Protein 2.3g
Biotin 3mcg
Total Fat 5.3g
Vitamin C 12mg
Total Carbohydrate 10.8g
Choline 24mg
Water 134g
Inositol 24mg
Omega-6 (linoleic acid LA) 780mg
Calcium 82mg
Vitamin A 300iu
Phosphorus 46mg
Vitamin D 60iu
Magnesium 8mg
Vitamin E 2iu
Iron 1.8mg
Vitamin K 1mcg
Zinc 1mg
Thiamin 15mcg
Manganese 140mcg
Copper 75mcg
Riboflavin 60mcg
Iodine 15mcg
Vitamin B6 0.3mcg
Selenium 2.8mcg
Vitamin B12 1000mcg
Sodium 40mg
Niacin 16mcg
Potassium 108mg
Folic Acid 500mcg
Pantothenic Acid 63mg
Chloride 63mg
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

corn syrup, nonfat milk, palm olein, partially hydrolyzed whey, soy oil, coconut oil, high oleic (safflower or sunflower) oil, less than 2%: 2'-fucosyllactose (2'-fl), mortierella alpina oil**, schizochytrium sp. oil** l-carnitine, mixed tocopherol concentrate, monoglycerides, soy lecithin, taurine, calcium carbonate, calcium chloride, cupric sulfate, ferrous sulfate, magnesium chloride, manganese sulfate, potassium bicarbonate, potassium hydroxide, potassium iodide, potassium phosphate, sodium citrate, sodium selenite, zinc sulfate, ascorbic acid, ascorbyl palmitate, beta-carotene, biotin, calcium pantothenate, choline bitartrate, cyanocobalamin, folic acid, inositol, niacinamide, pyridoxine hydrochloride, riboflavin, thiamin hydrochloride, vitamin a palmitate, vitamin d (cholecalciferol), vitamin e (di-alpha tocopheryl acetate), vitamin k (phytonadione).

Allergens & Warnings:

WARNING: DO NOT USE MICROWAVE TO PREPARE OR WARM FORMULA. SERIOUS BURNS MAY OCCUR., CONTAINS MILK AND SOY.
Dietary Needs: Gluten-Free, Kosher
Baby Formula Focus: Easy to Digest
Base Ingredient: Hydrolyzed Protein
State of Readiness: Mix
Form: Powdered
Package Quantity: 1
Age Stage: Infant
TCIN: 87765855
UPC: 085239987643
Item Number (DPCI): 007-09-0005
Origin: Made in the USA
Grocery Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers. Any additional pictures are suggested servings only.
If the item details aren’t accurate or complete, we want to know about it.

Shipping details

Estimated ship dimensions: 5.07 inches length x 5.28 inches width x 7.4 inches height
Estimated ship weight: 2.34 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest. If purchased online with SNAP EBT, this item must be returned within 90 days of the date it was shipped, delivered by a Shipt shopper, or made ready for pickup. This 90-day return window is required by SNAP.
See the return policy for complete information.

Q: What is the difference between gentle and gentle premium?

submitted by Guy asking question - 1 month ago

  • A: Hello guest - Thank you for your interest in this item. Gentle Premium is the updated version of the Gentle formula. It is designed for babies with fussiness, gas, and crying, and contains partially hydrolyzed whey protein, reduced lactose, and 2'-FL HMO for immune support. I hope this information helps. Happy Shopping! – Binu

    submitted byBinu - 1 month ago
    Target staff support

Q: Can I put a can of this formula in a checked bag on an airplane - will the temperature affect the formula?

submitted by c0urtney - 7 months ago

  • A: Hi! Thank you for your question! Optimum storage conditions of powder product is between 50°F and 86°F in a dry environment. The powdered product can tolerate temperatures outside of the optimum storage conditions for periods of short duration of week (7 days). We recommend visiting the TSA website for more information about formula as a carry-on item.

    submitted bythe Supplier - 7 months ago
    Brand expert

Q: What is the whey and casein ratio?

submitted by Hanh - 11 months ago

  • A: Hello, thank you for your question. The Up & Up Gentle formula has a 60 whey/40 casein ratio.

    submitted bythe Supplier - 11 months ago
    Brand expert

Q: Is using warm water a requirement to prepare it, or can I prepare with room temperature water?

submitted by Marina - 1 year ago

  • A: Hello, thank you for your question. For mixing formula, the water should be warm approximately 100F (40C). This is our recommendation as it is closest to the child’s body temperature and this will also help in the reconstitution of the formula.

    submitted bythe Supplier - 1 year ago
    Brand expert

Q: Is this the same as it used to be three years ago and just difference packaging than before?

submitted by Lisa0910 - 1 year ago

  • A: Hello, thank you for your question. We are still the manufacturing of the Up & Up infant formula. This is still the Gentle formula and is compared to the nutrition of Enfamil Neuropro Gentlease. Over the years there may have been some changes to the formulation to stay comparable to Enfamil and continue to support our little ones the best we can.

    submitted bythe Supplier - 1 year ago
    Brand expert
See all questions (5)

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Guests are saying

This formula has garnered mixed feedback from guests, with many praising its affordability and effectiveness for babies with sensitive stomachs. Guests appreciate its easy mixing and gentle nature, which has led to fewer digestive issues like gas and constipation for some. However, others have reported adverse reactions, including constipation and fussiness, suggesting that individual tolerance may vary. Overall, it presents a budget-friendly alternative to name brands, but results can differ significantly between babies.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.3 out of 5 stars with 583 reviews
    easy on tummy: 3.81 out of 5
    easy to prepare: 4.63 out of 5
    quality: 3.97 out of 5
    value: 4.12 out of 5
    65% would recommend
    152 recommendations
    3 out of 5 stars
    Thumbs up graphic, would recommend
    27 October, 2026Verified purchase

    Price changes

    My 10 month old has been on this since she was born. Since then, the price has increased several times.Ive never been so excited to be done with formula. Its been good, but pricing is so inconsistent.
    Catnado
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 3 out of 5
    Did you find this review helpful?
    2 out of 5 stars
    27 October, 2026Verified purchase

    (no review title)

    The price of this formula has fluctuated wildly over the past two months. First it was 23.99 followed by 20.99. Last week it was 31.99 and now 32.99. Absolutely ridiculous.
    Adesaulnier121
    1 guest found this review helpful. Did you?
    2 out of 5 stars
    Thumbs up graphic, would recommend
    25 October, 2026Verified purchase

    Horrible Price Increase

    Love this formula, hate the price increase. Bought this 3 weeks ago for $19 now it’s $32.99. Need to bring the price back down if we’re going to continue to buy.
    Alex
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 1 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    24 October, 2026Verified purchase

    (no review title)

    Never had any issues with this formula! Also nice that it goes on sale every once in a while without needing a coupon
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    4 out of 5 stars
    19 October, 2026Verified purchase

    (no review title)

    Love this formula just sucks that the price has increased this is the 3rd time the price is raised to 31.99 and then goes back down to 23.99
    Alissa
    1 guest found this review helpful. Did you?
    2 out of 5 stars
    Thumbs down graphic, would not recommend
    18 October, 2026Verified purchase

    Price increase

    I've used this for two babies from the day we got home from the hospital.. All of a sudden the price went up $10+. We already stopped using Target wipes, now I'll be finding an alternative Gentle formula.
    BNyquist
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 1 out of 5
    1 guest found this review helpful. Did you?
    4 out of 5 stars
    14 October, 2026Verified purchase

    Good formula but price increased

    This is the best alternative to name brand formula I’ve found but they increased the price from $24.99 to $33. Still cheaper than name brand but disappointing to see.
    Karynn
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    12 October, 2026Verified purchase

    Value !!

    Excellent. Comparable to enfamil gentle. My baby actually spits up less with this formula than enfamil. It made her poop dark for a little while, so I feel like it may have more iron than enfamil despite it not seeming that way. But that eventually stopped as she got used to it.
    Ebony
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    2 out of 5 stars
    5 October, 2026Verified purchase

    Price increase

    Switched to this formula recently and the price went up over $10 a can in just a few weeks! Initially bought for $19 a can now it’s $31.99!!
    Farmersdgtr
    value: 2 out of 5
    8 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    5 October, 2026Verified purchase

    (no review title)

    This is a cheaper alternative to the brand name GentleEase formula! Luckily for my family my baby took to the change well, after having the brand name for about four months.
    Miranda
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 4 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    26 September, 2026Verified purchase

    Amazing

    We found that this formula was way better on his belly. He hardly spits up and barely has any gas. We are so glad we found this cheaper alternative.
    Jessica
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    26 September, 2026Verified purchase

    (no review title)

    Huge fan of this formula and the frequent sales. Baby has tried Enfamil Gentleease, Similac 360 Total (purple), and Members Mark. This one takes the cake!
    Olive
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    16 September, 2026Verified purchase

    AVOID

    We thought it’d be a cheaper alternative to gentle ease but we learned the hard way how wrong we were. My poor baby had so much stomach pain with both constipation, gas and diarrhea. Not worth it, stick to name brand if it’s what works
    Bee
    From the Product Manufacturer team
    We are sorry to hear about your experience with the Up & Up Gentle Premium Powder Infant Formula product. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 1-800-272-5095 or via email by going to www.perrigo.com/contact-us and reference case number 2198825. We look forward to addressing your concerns and hearing from you!
    1 month ago
    easy on tummy: 1 out of 5
    easy to prepare: 5 out of 5
    quality: 1 out of 5
    value: 1 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs down graphic, would not recommend
    13 September, 2026Verified purchase

    gentle formula

    excited to try this brand out
    K
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    17 August, 2026Verified purchase

    Used since my child was born

    It took a couple of tries to find the right formula, after trying many, this was the one we chose. After a week, my child got used too this one, it’s affordable and meets the standards I was looking for. I looked into the ingredients and compared it with others and this definitely passed the test..
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    17 August, 2026Verified purchase

    not gentle

    not gentle on our baby girl, fussy and issues with constipation ever since we started using it. will be going back to enfamil
    Jared
    From the Product Manufacturer team
    We are sorry to hear about your experience with the Gentle Premium Powder Infant Formula - 34oz - up&up. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 1-800-272-5095 or via email by going to www.perrigo.com/contact-us and reference case number 2189902. We look forward to addressing your concerns and hearing from you!
    2 months ago
    easy on tummy: 1 out of 5
    easy to prepare: 5 out of 5
    quality: 2 out of 5
    value: 4 out of 5
    Did you find this review helpful?
    4 out of 5 stars
    Thumbs up graphic, would recommend
    14 August, 2026Verified purchase

    Good quality and reasonably priced

    Baby seems to like formula and has adjusted well.
    henrykath
    easy on tummy: 4 out of 5
    easy to prepare: 5 out of 5
    quality: 4 out of 5
    value: 4 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    13 August, 2026Verified purchase

    (no review title)

    I prefer this brand over the original name Brand
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    9 August, 2026Verified purchase

    (no review title)

    We love this formula
    BrookeK
    Did you find this review helpful?
    5 out of 5 stars
    7 August, 2026Verified purchase

    (no review title)

    Worth the money and the same as brand names
    Zill
    1 guest found this review helpful. Did you?

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