Advantage Premium Powder Infant Formula - 36oz - up&up™
$35.49 ($0.99/ounce)
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$33.99($1.02/ounce)
$64.58($0.97/ounce)
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$33.99($1.02/ounce)
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4.1 out of 5 stars with 441 reviews
easy on tummy: 4.07 out of 5
easy to prepare: 4.41 out of 5
quality: 4.03 out of 5
value: 4.02 out of 5
68% would recommend
190 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
28 January, 2026
(no review title)
my son likes it and didn't react negatively to this brand change.
5 out of 5 stars
8 January, 2026Verified purchase
(no review title)
Seamless transition from the overpriced name brand stuff. So so appreciative of this brand.
5 out of 5 stars
Thumbs up graphic, would recommend
23 December, 2025
Great formula
A great deal for a great formula. Our baby never spits it up and always drinks it, we’ve found our preferred formula.
3 out of 5 stars
15 December, 2025Verified purchase
(no review title)
Not the best smelling but baby doesn’t seem to notice a difference
1 reply from the Product Manufacturer team - 2 months ago
We are sorry to hear about the smell you noticed with the Up & Up Advantage Formula but are happy to hear your little one is enjoying it. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2112759. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
Thumbs down graphic, would not recommend
15 November, 2025Verified purchase
So much ..... wrong
So your formula price DOUBLES since 2021 and …. It’s now in a can with a metal bottom that scratches glass top stoves (a common place for making a bottle). And it’s in a cardboard can that dissolves if water splashes on it. AND …. There is no SCRAPPER part to LEVEL the scoop?! Sincerely a postpartum mom who is overstimulated and annoyed by the simple things formula is now not.
1 reply from the Product Manufacturer team - 3 months ago
We are sorry to hear about your frustrations with the packaging of the Up & Up Advantage Formula. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2102816. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
15 October, 2025
(no review title)
There are what appears to be small metal/aluminum shavings in the can. I ran my finger around the rim where a lot of it was and it was very dusty like. Be sure to check it!!
1 reply from the Product Manufacturer team - 4 months ago
We are sorry to hear about your experience with the particles found. The material you may have observed on the exterior of the EZO (easy open) end and/or overcaps is wear from conveyors and components, combined with a dusting of infant formula, that accumulates on conveyor belts during the normal packaging process. We do not have toxic materials in our packaging process that you should be concerned with, but like any manufacturing facility, cans are not sterile after coming off our packaging line. We recommend best practice is to wipe down can tops before opening and use. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2092934. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
28 September, 2025Verified purchase
Pieces of black stuff
Yeah absolutely not getting anymore i’ve been getting this for a month now this last can that I just got has a black floaters after mixing. And my daughter’s been getting stomach aches.
1 reply from the Product Manufacturer team - 4 months ago
We are sorry to hear about your experience with the Up & Up Advantage formula. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2086945. We look forward to addressing your concerns and hearing from you!
5 out of 5 stars
Thumbs up graphic, would recommend
19 September, 2025Verified purchase
Fishy smell goes away!
I wanted to make sure to leave a review for this one because so many people gave it a poor review because of the smell. I want to clarify... when you open the container, there is absolutely a strong fishy smell HOWEVER you only smell it the first time you open the container - never again. Spit up doesn't smell, burps don't smell... Yes, the smell is icky when you originally open the container but that's it. We switched to this formula to save some money and it was a flawless transition, highly recommend.
1 out of 5 stars
Thumbs down graphic, would not recommend
3 September, 2025Verified purchase
I'll spend more on the name brand.
The smell is awful. It's like a fishy smell and my newborns BMS smell fishy too. It makes me gag. Plus, my baby barfed up a lot. She never did this when she was on the name brand stuff.
1 reply from the Product Manufacturer team - 5 months ago
We are sorry to hear about your experience with the Up & Up Advantage Formula. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2080122. We look forward to addressing your concerns and hearing from you!
5 out of 5 stars
Thumbs up graphic, would recommend
20 August, 2025Verified purchase
99% the same as Similac 360 total care
I compared the ingredients to similar 360 total care which I used to use on my baby and they are 99% the same exact 1% difference in one ingredient that they both have. They are basically the exact same formula just one a name brand. My baby enjoys it the same as similar 360 and we had had no problem at all. Happy with the formula. Will continue to buy.
3 out of 5 stars
13 August, 2025Verified purchase
Reaction
This formula is inexpensive and probably great! However, my baby broke out in hives from drinking & coming into contact with the prepared formula. Customer service offered a refund & took down a report, showing great concern that their product resulted in hives for my 6 month old. It does have a fishy smell, but formula has never smelt the greatest in my opinion. Not discrediting this formula, but just wanted to give our experience to proceed with caution.
1 reply from the Product Manufacturer team - 6 months ago
We are sorry to hear that the Advantage formula was not a good fit for your little one. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2073420. We look forward to addressing your concerns and hearing from you!
5 out of 5 stars
Thumbs up graphic, would recommend
25 July, 2025
Good for the price
My baby was originally on Similac 360. This is the closest alternative. She didn't have any tummy issues or spit up after we switched.
5 out of 5 stars
Thumbs up graphic, would recommend
24 July, 2025
Perfect for my baby!
Good formula overall compared to Similac 360 total care. We always purchased the brand but this is just as good as the orignial. My baby loves it and has no complications. It lasts us almost 2 weeks. PLUS great pricing compared to the brand. Will definitley repurchase this item.
5 out of 5 stars
Thumbs up graphic, would recommend
16 July, 2025Verified purchase
Up ans Up formula
Good formula overall compared to Similac 360/Advance. Has a slightly fish smell but that’s just due to the iron. Baby takes it just fine
4 out of 5 stars
Thumbs up graphic, would recommend
8 July, 2025Verified purchase
Good price, bad smell
Weird fish smell, otherwise ok and a good price
1 out of 5 stars
Thumbs down graphic, would not recommend
7 July, 2025Verified purchase
Caused gas and projectile vomit
My one month old was super gassy, fussy, and throw up ALOT with this. Switch her back to name brand and didn’t have the issue anymore. Tried this cause it was cheaper, unfortunately it didn’t work for us. Will not use again.
1 reply from the Product Manufacturer team - 7 months ago
We are sorry to hear that the formula was not a good fit for your little one. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2061101. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
Thumbs down graphic, would not recommend
20 June, 2025Verified purchase
Caused spit up
Made my baby spit up a ton. Kept him on it for a couple weeks to see if he would adjust but he never did. He is fine on Similac advance and Similac total care but was non stop spitting up with Up and Up.
1 reply from the Product Manufacturer team - 7 months ago
We are sorry to hear about your experience with the Up & Up Formula. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We encourage you to reach out to our contact center at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2056005. We look forward to addressing your concerns and hearing from you!
3 out of 5 stars
Thumbs down graphic, would not recommend
19 June, 2025Verified purchase
Smell was awful.
Good for the price . But sent was nasty. Smelled like fish.
1 reply from the Product Manufacturer team - 8 months ago
We are sorry to hear about the smell of the formula. Infant formula powders with DHA/ARA may be generally described as a “fishy” smell and this is very normal. Our formulas have a target aroma profile however, due to variation in the ingredients, there may be variation from one lot to the next. This range is within acceptable quality and safety standards. We encourage you to reach out to our contact center at 1-800-272-5095 or email by going to www.perrigo.com/contact-us and reference case number 2055062. We look forward to addressing your concerns and hearing from you!
5 out of 5 stars
Thumbs up graphic, would recommend
13 June, 2025Verified purchase
Great value
Same price as the comparable Similac(recently went up to $38) but 6 more ounces.
5 out of 5 stars
Thumbs up graphic, would recommend
1 June, 2025Verified purchase
Formula
Very comparable to similac just much cheaper!