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Alka-Seltzer Plus Severe Cold & Flu Night Powder, 6 Count
New at target
$12.61
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About this item
Highlights
- Nighttime powder relieves fever, cough, and congestion effectively.
- Single-serve packets mix into warm, soothing lemon-flavored drinks.
- 6 count pack provides convenient overnight cold symptom relief.
- Fast-absorbing format supports better rest and comfort at night.
- Trusted Alka-Seltzer Plus brand ensures reliable severe cold care.
Description
Alka-Seltzer Plus Severe Cold & Flu Night Powder delivers targeted overnight relief for multiple symptoms. Each of the 6 packets contains a powder designed to be mixed with water for fast-acting relief of fever, cough, sore throat, congestion, and body aches. The soothing warm drink helps users rest more comfortably through the night. Compact and easy to use, these single-serve packets are convenient for at-home use or travel. Trusted for effectiveness, Alka-Seltzer Plus provides a dependable solution for nighttime cold and flu management in a convenient powder format.
Suggested Age: 18 Years and Up
Product Warning: Keep out of reach of children
Product Form: Powder
Primary Active Ingredient: Aspirin
Package Quantity: 6
TCIN: 1005870316
UPC: 016500559399
Origin: made in the USA or imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
The above item details were provided by the Target Plus™ Partner. Target does not represent or warrant that this information is accurate or complete. On occasion, manufacturers may modify their items and update their labels.
We recommend that you do not rely solely on the information presented. If you have a specific question about this item, you may consult the item's label, contact the manufacturer directly or call Target Guest Services at 1-800-591-3869.
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Acetaminophen(650mg), Dextromethorphan Hydrobromide(20mg), Doxylamine Succinate(12.5mg), Phenylephrine Hydrochloride(10mg).
Pain Reliever/Fever Reducer, Cough Suppressant, Antihistamine, Nasal Decongestant..
headache, minor aches and pains, cough, sore throat, nasal congestion, sinus congestion and pressure, runny nose, sneezing
Allergy Alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include:
Allergy Alert: Acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include:: skin reddening,blisters,rash,hives,facial swelling,asthma (wheezing),shock,if a skin or general allergic reaction occurs, stop use and seek medical help right away.Do not use
Do not use: with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist,if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product,if you have ever had an allergic reaction to this product or any of its ingredients,in children under 12 years of age.Ask a doctor before use if you have
Ask a doctor before use if you have: liver disease,heart disease,high blood pressure,thyroid disease,diabetes,glaucoma,cough with excessive phlegm (mucus),a breathing problem such as emphysema or chronic bronchitis,difficulty in urination due to enlargement of the prostate gland,persistent or chronic cough such as occurs with smoking, asthma, or emphysema.Ask a doctor or pharmacist before use if you are
Ask a doctor or pharmacist before use if you are: taking the blood thinning drug warfarin,taking sedatives or tranquilizers.When using this product
When using this product: do not exceed recommended dosage,may cause marked drowsiness,avoid alcoholic drinks,alcohol, sedatives, and tranquilizers may increase drowsiness,be careful when driving a motor vehicle or operating machinery,excitability may occur, especially in children.Stop use and ask a doctor if
Stop use and ask a doctor if: pain, cough, or nasal congestion gets worse or lasts more than 7 days,fever gets worse or lasts more than 3 days,redness or swelling is present,new symptoms occur,cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition,nervousness, dizziness, or sleeplessness occurs.Do not take more than the recommended dose. Take every 4 hours; do not exceed 5 packets in 24 hours or as directed by a doctor. Feel Better Fast: Mix the Alka-Seltzer Plus fast relief mix-in packet into 8 oz. of hot water. Sip the soothing beverage within 10-15 minutes. Experience the steam and the tasty drink as it infuses powerful relief through your whole body.
Adults and Children 12 Years and Over
Dissolve contents of one packet in 8 oz. hot water; sip while hot. Consume entire drink within 10-15 minutes.Children Under 12 Years
Do not use.Each Packet Contains: Potassium 5 mg and sodium 5 mg. Store at room temperature.
Inactive ingredients
acesulfame potassium, anhydrous citric acid, compressible sugar, d&c yellow 10, dental-type silica, fd&c red 40, flavors, pregelatinized starch, sodium citrate, sucralose, tartaric acid, tribasic calcium phoshpate
800-986-0369
Ingredients:
acesulfame potassium, anhydrous citric acid, compressible sugar, d&c yellow #10, dental-type silica, fd&c red #40, flavors, pregelatinized starch, sodium citrate, sucralose, tartaric acid, tribasic calcium phosphate' '
Allergens & Warnings:
IF PREGNANT OR BREAST-FEEDING, ASK A HEALTH PROFESSIONAL BEFORE USE. KEEP OUT OF REACH OF CHILDREN. IN CASE OF OVERDOSE, GET MEDICAL HELP OR CONTACT A POISON CONTROL CENTER RIGHT AWAY. QUICK MEDICAL ATTENTION IS CRITICAL FOR ADULTS AS WELL AS FOR CHILDREN EVEN IF YOU DO NOT NOTICE ANY SIGNS OR SYMPTOMS., WHEN USING THIS PRODUCT - DO NOT EXCEED RECOMMENDED DOSAGE, MAY CAUSE MARKED DROWSINESS, AVOID ALCOHOLIC DRINKS, ALCOHOL, SEDATIVES, AND TRANQUILIZERS MAY INCREASE DROWSINESS, BE CAREFUL WHEN DRIVING A MOTOR VEHICLE OR OPERATING MACHINERY, EXCITABILITY MAY OCCUR, ESPECIALLY IN CHILDREN, ASK A DOCTOR OR PHARMACIST BEFORE USE IF YOU ARE - TAKING THE BLOOD THINNING DRUG WARFARIN, TAKING SEDATIVES OR TRANQUILIZERS, DO NOT USE - WITH ANY OTHER DRUG CONTAINING ACETAMINOPHEN (PRESCRIPTION OR NONPRESCRIPTION). IF YOU ARE NOT SURE WHETHER A DRUG CONTAINS ACETAMINOPHEN, ASK A DOCTOR OR PHARMACIST. IF YOU ARE NOW TAKING A PRESCRIPTION MONOAMINE OXIDASE INHIBITOR (MAOI) (CERTAIN DRUGS FOR DEPRESSION, PSYCHIATRIC, OR EMOTIONAL CONDITIONS, OR PARKINSON'S DISEASE), OR FOR 2 WEEKS AFTER STOPPING THE MAOI DRUG. IF YOU DO NOT KNOW IF YOUR PRESCRIPTION DRUG CONTAINS AN MAOI, ASK A DOCTOR OR PHARMACIST BEFORE TAKING THIS PRODUCT. IF YOU HAVE EVER HAD AN ALLERGIC REACTION TO THIS PRODUCT OR ANY OF ITS INGREDIENTS, IN CHILDREN UNDER 12 YEARS OF AGE, STOP USE AND ASK A DOCTOR IF - PAIN, COUGH, OR NASAL CONGESTION GETS WORSE OR LASTS MORE THAN 7 DAYS, FEVER GETS WORSE OR LASTS MORE THAN 3 DAYS, REDNESS OR SWELLING IS PRESENT, NEW SYMPTOMS OCCUR, COUGH COMES BACK OR OCCURS WITH RASH OR HEADACHE THAT LASTS. THESE COULD BE SIGNS OF A SERIOUS CONDITION. NERVOUSNESS, DIZZINESS, OR SLEEPLESSNESS OCCURS, ASK A DOCTOR BEFORE USE IF YOU HAVE - LIVER DISEASE, HEART DISEASE, HIGH BLOOD PRESSURE, THYROID DISEASE, DIABETES, GLAUCOMA, COUGH WITH EXCESSIVE PHLEGM (MUCUS), A BREATHING PROBLEM SUCH AS EMPHYSEMA OR CHRONIC BRONCHITIS, DIFFICULTY IN URINATION DUE TO ENLARGEMENT OF THE PROSTATE GLAND, PERSISTENT OR CHRONIC COUGH SUCH AS OCCURS WITH SMOKING, ASTHMA, OR EMPHYSEMA, LIVER WARNING: THIS PRODUCT CONTAINS ACETAMINOPHEN. SEVERE LIVER DAMAGE MAY OCCUR IF YOU TAKE - MORE THAN 5 PACKETS IN 24 HOURS, WHICH IS THE MAXIMUM DAILY AMOUNT FOR THIS PRODUCT, WITH OTHER DRUGS CONTAINING ACETAMINOPHEN, 3 OR MORE ALCOHOLIC DRINKS EVERY DAY WHILE USING THIS PRODUCT; ALLERGY ALERT: ACETAMINOPHEN MAY CAUSE SEVERE SKIN OR SEVERE ALLERGIC REACTIONS. SYMPTOMS MAY INCLUDE: SKIN REDDENING, BLISTERS, RASH, HIVES, FACIAL SWELLING, ASTHMA (WHEEZING), SHOCK, IF A SKIN OR GENERAL ALLERGIC REACTION OCCURS, STOP USE AND SEEK MEDICAL HELP RIGHT AWAY. SORE THROAT WARNING: IF SORE THROAT IS SEVERE, PERSISTS FOR MORE THAN 2 DAYS, IS ACCOMPANIED OR FOLLOWED BY FEVER, HEADACHE, RASH, NAUSEA, OR VOMITING, CONSULT A DOCTOR PROMPTLY. DO NOT USE TO SEDATE CHILDREN.Shipping details
Estimated ship dimensions: 5 inches length x 3 inches width x 1.9 inches height
Estimated ship weight: 0.17 pounds
item ships from third party seller: Hey Pharma
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 30 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
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Guests are saying
Alka Seltzer Plus Cold and Flu is a highly effective over-the-counter medication that provides quick relief from multiple cold and flu symptoms. Guests appreciate its soothing hot drink form, which is easy to prepare and helps alleviate discomfort. The product is praised for its fast-acting formula, pleasant taste, and convenience, making it a go-to choice for families during cold season. Many guests recommend it for its ability to help them sleep better and feel better quickly.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.6 out of 5 stars with 300 reviews
4 out of 5 stars
6 October, 2025
originally posted on influenster.com

Powerful relief
Quickly clears up those stubborn sinus issues and cold symptoms! Feeling so much better—a great buy that truly delivers. This helps falling asleep and staying asleep during bad fits.
5 out of 5 stars
30 August, 2025
originally posted on influenster.com

Really helps with cold symptoms for overnight reli
Love this product. Everyone in my family uses it when needed. I have always really liked this medicine, it really makes you feel better quickly. Alka seltzer is the only brand that get my cold under control. I love the hot drink they have, just seems soothing when you’re not feeling well. We are so happy with this purchase. Thank you
5 out of 5 stars
20 August, 2025
originally posted on influenster.com

A must-have have for cold relief
Alka-Seltzer Plus Cold and Flu is a convenient over-the-counter medication designed to relieve multiple cold and flu symptoms at once, including nasal congestion, headache, body aches, fever, sore throat, and sometimes cough. Its effervescent tablets dissolve in water, making it quick-acting and potentially easier on the stomach than traditional pills. The formula typically includes ingredients like acetaminophen for pain and fever, phenylephrine for congestion, and sometimes antihistamines or cough suppressants, offering broad-spectrum symptom relief. Available in both daytime and nighttime versions, it helps manage symptoms around the clock without causing unwanted drowsiness during the day. However, it’s not suitable for everyone, especially those with certain medical conditions or who are taking other medications, so it's important to use it as directed.
5 out of 5 stars
6 August, 2025
originally posted on influenster.com

Like you're not sick at all!
Great stuff! I've tried other cold medicines assuming they just didn't work for me before finding Alka Seltzer's line of products. This one works particularly well, one dose keeps me breathing clear and with no headache all night. I'm someone who avoids using medicine when I can get away with it but the difference in how I feel makes this product 100% worth it. It takes me from miserable to feeling like I'm barely sick or even not sick at all.
5 out of 5 stars
30 July, 2025
originally posted on influenster.com

Best cold and flu medication
I absolutely love Alka seltzer, it is my go to over the counter cold medication. It is affordable. The medication tastes amazing. even when you have a cold and the packaging is easy for on the go use. I would recommend
5 out of 5 stars
22 July, 2025
originally posted on influenster.com

Good Night
I was surprised by how quickly it worked. The taste is strong but tolerable. I looked into the ingredients, and it has a solid mix for nighttime ✨✌🏻
5 out of 5 stars
3 July, 2025
originally posted on influenster.com

Great for cold and flu season
Alka Seltzer has been my go to for colds and flu since I can remember. This medicine will get you right every time. I love the taste. Great value for the price.
5 out of 5 stars
10 June, 2025
originally posted on influenster.com

Taste
This drink immediately soothes your throat and helps you rest. It doesn’t take bad but it does have a strong taste. I would recommend to anyone to try.
5 out of 5 stars
6 June, 2025
originally posted on influenster.com

Great!
Ingredients are effective and safe packaged well and good value for your money, easy to drink and will be buying the next time flu hits our house.
5 out of 5 stars
5 June, 2025
originally posted on influenster.com

It works
I prefer the night version of Alka-Seltzer. Very high quality product. I use this first if I am feeling ill. Puts me write to sleep but I do not feel like I am dragging as long as I get about 7 hours of sleep. The taste is is kind of like a Sprite or seltzer water. The packaging is pretty easy to open unlike Nyquil pills.
5 out of 5 stars
3 June, 2025
originally posted on influenster.com

Quick relief!
This has always been a go to for cold season for my family! It helps me when I get super congested and gives me relief! I feel relief after one dose and usually keep it on hand.
5 out of 5 stars
3 June, 2025
originally posted on influenster.com

Go to
My go to when I am under the weather, it’s super easy and simple to use these the taste is so good and helps right away! Also I like that it’s not so cost worthy I buy a box and only use a few tablets so I always have them on stand by.
5 out of 5 stars
1 June, 2025
originally posted on influenster.com

Works wonders
I love this stuff! It works so good helping with sick symptoms and the taste isn't too horrible. Great value for your money and it lasts. I will always buy this for myself and my family.
4 out of 5 stars
9 March, 2023
originally posted on influenster.com

The taste of this
The taste of this is pretty bitter, but it works really well if you make sure to drink it regularly. Next time I’ll also buy the day one and see how that combo works.
5 out of 5 stars
16 February, 2023
originally posted on influenster.com

Works
This stuff works so well. I don't mind taking the pill form but the powder works so much better and faster. Its easy to use and helps that its in warm water to relieve some of the throat irritation
5 out of 5 stars
10 September, 2022
originally posted on influenster.com

#ItWorksIJS
This product is a must have. You can feel the difference routinely the hour. Must have for fall and winter. Dependable
5 out of 5 stars
8 July, 2022
originally posted on influenster.com

GENTLE
I have a sensitive stomach and this is the only cold or flu Med that doesn’t make me nauseas . I always have it on hand. It’s not as strong as other ones in terms of pain management so I still have mild pain or headaches
4 out of 5 stars
29 June, 2022
originally posted on influenster.com

alba seltzer
I would say that we should all always have this at home, totally essential in the first aid kit. relieves stomach discomfort, gas, flatulence and a feeling of fullness
5 out of 5 stars
23 June, 2022
originally posted on influenster.com

Good medicine
This medicine sure made me feel better. I dont like the taste at all, but just knowing how much better it makes me feel, I can get through the taste.
5 out of 5 stars
24 May, 2022
originally posted on influenster.com

Best Alka seltzer cold product
I usually rely on Alka seltzer for my over-the counter cold and flu products; and I have ever since I was a child. My parents used it as well. Very great product for this household.