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Alka-Seltzer Plus Severe Cold & Flu Night Powder, Nighttime Multi-Symptom Relief for Cough, Congestion & Fever, 6 Packets
$12.61
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About this item
Highlights
- Nighttime powder relieves fever, cough, and congestion effectively.
- Single-serve packets mix into warm, soothing lemon-flavored drinks.
- 6 count pack provides convenient overnight cold symptom relief.
- Fast-absorbing format supports better rest and comfort at night.
- Trusted Alka-Seltzer Plus brand ensures reliable severe cold care.
Description
Alka-Seltzer Plus Severe Cold & Flu Night Powder delivers targeted overnight relief for multiple symptoms. Each of the 6 packets contains a powder designed to be mixed with water for fast-acting relief of fever, cough, sore throat, congestion, and body aches. The soothing warm drink helps users rest more comfortably through the night. Compact and easy to use, these single-serve packets are convenient for at-home use or travel. Trusted for effectiveness, Alka-Seltzer Plus provides a dependable solution for nighttime cold and flu management in a convenient powder format.
Suggested Age: 18 Years and Up
Product Warning: Keep out of reach of children
Product Form: Powder
Primary Active Ingredient: Aspirin
Package Quantity: 6
TCIN: 1005870316
UPC: 016500559399
Origin: made in the USA or imported
Healthcare Disclaimer:
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Ingredients:
acesulfame potassium, anhydrous citric acid, compressible sugar, d&c yellow #10, dental-type silica, fd&c red #40, flavors, pregelatinized starch, sodium citrate, sucralose, tartaric acid, tribasic calcium phosphate' '
Allergens & Warnings:
IF PREGNANT OR BREAST-FEEDING, ASK A HEALTH PROFESSIONAL BEFORE USE. KEEP OUT OF REACH OF CHILDREN. IN CASE OF OVERDOSE, GET MEDICAL HELP OR CONTACT A POISON CONTROL CENTER RIGHT AWAY. QUICK MEDICAL ATTENTION IS CRITICAL FOR ADULTS AS WELL AS FOR CHILDREN EVEN IF YOU DO NOT NOTICE ANY SIGNS OR SYMPTOMS., WHEN USING THIS PRODUCT - DO NOT EXCEED RECOMMENDED DOSAGE, MAY CAUSE MARKED DROWSINESS, AVOID ALCOHOLIC DRINKS, ALCOHOL, SEDATIVES, AND TRANQUILIZERS MAY INCREASE DROWSINESS, BE CAREFUL WHEN DRIVING A MOTOR VEHICLE OR OPERATING MACHINERY, EXCITABILITY MAY OCCUR, ESPECIALLY IN CHILDREN, ASK A DOCTOR OR PHARMACIST BEFORE USE IF YOU ARE - TAKING THE BLOOD THINNING DRUG WARFARIN, TAKING SEDATIVES OR TRANQUILIZERS, DO NOT USE - WITH ANY OTHER DRUG CONTAINING ACETAMINOPHEN (PRESCRIPTION OR NONPRESCRIPTION). IF YOU ARE NOT SURE WHETHER A DRUG CONTAINS ACETAMINOPHEN, ASK A DOCTOR OR PHARMACIST. IF YOU ARE NOW TAKING A PRESCRIPTION MONOAMINE OXIDASE INHIBITOR (MAOI) (CERTAIN DRUGS FOR DEPRESSION, PSYCHIATRIC, OR EMOTIONAL CONDITIONS, OR PARKINSON'S DISEASE), OR FOR 2 WEEKS AFTER STOPPING THE MAOI DRUG. IF YOU DO NOT KNOW IF YOUR PRESCRIPTION DRUG CONTAINS AN MAOI, ASK A DOCTOR OR PHARMACIST BEFORE TAKING THIS PRODUCT. IF YOU HAVE EVER HAD AN ALLERGIC REACTION TO THIS PRODUCT OR ANY OF ITS INGREDIENTS, IN CHILDREN UNDER 12 YEARS OF AGE, STOP USE AND ASK A DOCTOR IF - PAIN, COUGH, OR NASAL CONGESTION GETS WORSE OR LASTS MORE THAN 7 DAYS, FEVER GETS WORSE OR LASTS MORE THAN 3 DAYS, REDNESS OR SWELLING IS PRESENT, NEW SYMPTOMS OCCUR, COUGH COMES BACK OR OCCURS WITH RASH OR HEADACHE THAT LASTS. THESE COULD BE SIGNS OF A SERIOUS CONDITION. NERVOUSNESS, DIZZINESS, OR SLEEPLESSNESS OCCURS, ASK A DOCTOR BEFORE USE IF YOU HAVE - LIVER DISEASE, HEART DISEASE, HIGH BLOOD PRESSURE, THYROID DISEASE, DIABETES, GLAUCOMA, COUGH WITH EXCESSIVE PHLEGM (MUCUS), A BREATHING PROBLEM SUCH AS EMPHYSEMA OR CHRONIC BRONCHITIS, DIFFICULTY IN URINATION DUE TO ENLARGEMENT OF THE PROSTATE GLAND, PERSISTENT OR CHRONIC COUGH SUCH AS OCCURS WITH SMOKING, ASTHMA, OR EMPHYSEMA, LIVER WARNING: THIS PRODUCT CONTAINS ACETAMINOPHEN. SEVERE LIVER DAMAGE MAY OCCUR IF YOU TAKE - MORE THAN 5 PACKETS IN 24 HOURS, WHICH IS THE MAXIMUM DAILY AMOUNT FOR THIS PRODUCT, WITH OTHER DRUGS CONTAINING ACETAMINOPHEN, 3 OR MORE ALCOHOLIC DRINKS EVERY DAY WHILE USING THIS PRODUCT; ALLERGY ALERT: ACETAMINOPHEN MAY CAUSE SEVERE SKIN OR SEVERE ALLERGIC REACTIONS. SYMPTOMS MAY INCLUDE: SKIN REDDENING, BLISTERS, RASH, HIVES, FACIAL SWELLING, ASTHMA (WHEEZING), SHOCK, IF A SKIN OR GENERAL ALLERGIC REACTION OCCURS, STOP USE AND SEEK MEDICAL HELP RIGHT AWAY. SORE THROAT WARNING: IF SORE THROAT IS SEVERE, PERSISTS FOR MORE THAN 2 DAYS, IS ACCOMPANIED OR FOLLOWED BY FEVER, HEADACHE, RASH, NAUSEA, OR VOMITING, CONSULT A DOCTOR PROMPTLY. DO NOT USE TO SEDATE CHILDREN.Shipping details
Estimated ship dimensions: 5 inches length x 3 inches width x 1.9 inches height
Estimated ship weight: 0.17 pounds
item ships from third party seller: Hey Pharma
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 30 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
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Guests are saying
Alka Seltzer Plus Cold and Flu is a highly effective over-the-counter medication that provides quick relief from multiple cold and flu symptoms. Guests appreciate its soothing hot drink form, which is easy to prepare and helps alleviate discomfort. The product is praised for its fast-acting formula, pleasant taste, and convenience, making it a go-to choice for families during cold season. Many guests recommend it for its ability to help them sleep better and feel better quickly.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.6 out of 5 stars with 308 reviews
5 out of 5 stars
29 November, 2025
originally posted on influenster.com

Strongly recommend.
I wish this was easier to find, because in our experience it is by far the best "hot liquid cold/flu remedy" out there. The fizzy pills and capsules aren't nearly as effective. This review is for the Night version, and as I type my husband is snoring in the bedroom. Seriously, this will knock you out. Consistency is good . Ingredients nice . do NOT take this and plan to drive somewhere in a n hour or so. If you have to do anything that requires consciousness, take the day version. They both are great. They WORK. I would give them six stars if I could.
4 out of 5 stars
19 November, 2025
originally posted on influenster.com

I tried the Alka-Seltzer Plus Severe Cold + Flu Ni
I tried the Alka-Seltzer Plus Severe Cold + Flu Night and it really helped me manage my symptoms. I was dealing with congestion, body aches, a sore throat, and a bad cough, and within about 30–45 minutes I started feeling calmer and able to rest. It made it easier to sleep through the night without constant coughing. The relief lasted several hours, and I woke up feeling noticeably better. It does make you sleepy, so definitely take it only at night. Overall, it worked fast and gave me genuine comfort when I felt my worst.
4 out of 5 stars
14 November, 2025
originally posted on influenster.com

Worth it
Relief is pretty instant with this product. The taste is a little funky in my opinion but I feel like it mixes with water well, no gritty texture and you get a good amount for what you pay for - great value.
5 out of 5 stars
30 October, 2025
originally posted on influenster.com

Fast acting!
I am a believer, hands down, in this product! It’s fast acting, the flavor isn’t nasty, and it doesn’t break the bank! It’s best in hot water! The non-gritty formula make it even easier to take!
5 out of 5 stars
24 October, 2025
originally posted on influenster.com

A must!!
This is the best flu medicine I’ve ever used. I love the busy bubbly way that it goes down your throat. It’s so easy to make and it taste great they have different flavors. There’s a nighttime one. Also that really helps with great sleep and anytime I sick I always get this. It’s a great value for your money and it comes in individual packages so it’s easy to take on the go. If you need to. I hope you feel better soon. This will definitely help you.
5 out of 5 stars
20 October, 2025
originally posted on influenster.com

My go to product
I found the scent to be mild and pleasant—there’s a gentle citrus-lemon aroma that’s far more soothing than many cold medications. The packaging is smart and compact: the individual doses are clearly marked and the box is sturdy, though I did find the outer flap a little stiff to open when feeling under the weather. In terms of relief, it does pretty well — I felt my congestion, body-ache and headache ease within a couple of hours, and the night formula helped me drift off without feeling overly groggy in the morning. For value for money, it hits a sweet spot: the price is reasonable for a multi-symptom night treatment, and given how much better I slept and felt compared to doing nothing it seems worth it. Overall effectiveness: solid — it won’t replace a full rest day or doctor visit when you’re very sick, but it’s a dependable ally for getting through a rough night.
5 out of 5 stars
13 October, 2025
originally posted on influenster.com

Amazing
Came in handy when my son was sick he took them with ease and was able to getting back on his feet. Ended up biting it at the store was worth every penny!! My son said the taste is much better than normal cold medicine.
4 out of 5 stars
6 October, 2025
originally posted on influenster.com

Powerful relief
Quickly clears up those stubborn sinus issues and cold symptoms! Feeling so much better—a great buy that truly delivers. This helps falling asleep and staying asleep during bad fits.
5 out of 5 stars
14 September, 2025
originally posted on influenster.com

The best
The best prices it works so good for the price we pay very effective all natural ingredients and the scent is awesome as well as the packaging is also very nice as well
5 out of 5 stars
30 August, 2025
originally posted on influenster.com

Really helps with cold symptoms for overnight reli
Love this product. Everyone in my family uses it when needed. I have always really liked this medicine, it really makes you feel better quickly. Alka seltzer is the only brand that get my cold under control. I love the hot drink they have, just seems soothing when you’re not feeling well. We are so happy with this purchase. Thank you
5 out of 5 stars
20 August, 2025
originally posted on influenster.com

A must-have have for cold relief
Alka-Seltzer Plus Cold and Flu is a convenient over-the-counter medication designed to relieve multiple cold and flu symptoms at once, including nasal congestion, headache, body aches, fever, sore throat, and sometimes cough. Its effervescent tablets dissolve in water, making it quick-acting and potentially easier on the stomach than traditional pills. The formula typically includes ingredients like acetaminophen for pain and fever, phenylephrine for congestion, and sometimes antihistamines or cough suppressants, offering broad-spectrum symptom relief. Available in both daytime and nighttime versions, it helps manage symptoms around the clock without causing unwanted drowsiness during the day. However, it’s not suitable for everyone, especially those with certain medical conditions or who are taking other medications, so it's important to use it as directed.
5 out of 5 stars
6 August, 2025
originally posted on influenster.com

Like you're not sick at all!
Great stuff! I've tried other cold medicines assuming they just didn't work for me before finding Alka Seltzer's line of products. This one works particularly well, one dose keeps me breathing clear and with no headache all night. I'm someone who avoids using medicine when I can get away with it but the difference in how I feel makes this product 100% worth it. It takes me from miserable to feeling like I'm barely sick or even not sick at all.
5 out of 5 stars
30 July, 2025
originally posted on influenster.com

Best cold and flu medication
I absolutely love Alka seltzer, it is my go to over the counter cold medication. It is affordable. The medication tastes amazing. even when you have a cold and the packaging is easy for on the go use. I would recommend
5 out of 5 stars
22 July, 2025
originally posted on influenster.com

Good Night
I was surprised by how quickly it worked. The taste is strong but tolerable. I looked into the ingredients, and it has a solid mix for nighttime ✨✌🏻
5 out of 5 stars
3 July, 2025
originally posted on influenster.com

Great for cold and flu season
Alka Seltzer has been my go to for colds and flu since I can remember. This medicine will get you right every time. I love the taste. Great value for the price.
5 out of 5 stars
10 June, 2025
originally posted on influenster.com

Taste
This drink immediately soothes your throat and helps you rest. It doesn’t take bad but it does have a strong taste. I would recommend to anyone to try.
5 out of 5 stars
6 June, 2025
originally posted on influenster.com

Great!
Ingredients are effective and safe packaged well and good value for your money, easy to drink and will be buying the next time flu hits our house.
5 out of 5 stars
5 June, 2025
originally posted on influenster.com

It works
I prefer the night version of Alka-Seltzer. Very high quality product. I use this first if I am feeling ill. Puts me write to sleep but I do not feel like I am dragging as long as I get about 7 hours of sleep. The taste is is kind of like a Sprite or seltzer water. The packaging is pretty easy to open unlike Nyquil pills.
5 out of 5 stars
3 June, 2025
originally posted on influenster.com

Quick relief!
This has always been a go to for cold season for my family! It helps me when I get super congested and gives me relief! I feel relief after one dose and usually keep it on hand.
5 out of 5 stars
3 June, 2025
originally posted on influenster.com

Go to
My go to when I am under the weather, it’s super easy and simple to use these the taste is so good and helps right away! Also I like that it’s not so cost worthy I buy a box and only use a few tablets so I always have them on stand by.