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Alka-Seltzer Plus PowerFast Fizz NSAID Severe Cold & Cough Treatment - Citrus Lemon - 24ct - 2 of 4Alka-Seltzer Plus PowerFast Fizz NSAID Severe Cold & Cough Treatment - Citrus Lemon - 24ct - 3 of 4Alka-Seltzer Plus PowerFast Fizz NSAID Severe Cold & Cough Treatment - Citrus Lemon - 24ct - 4 of 4
Alka-Seltzer Plus PowerFast Fizz NSAID Severe Cold & Cough Treatment - Citrus Lemon - 24ct - 1 of 4

Alka-Seltzer Plus PowerFast Fizz NSAID Severe Cold & Cough Treatment - Citrus Lemon - 24ct

$9.69

In Stock

Eligible for registries and wish lists

At a glance

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About this item

Highlights

  • Unbeatably Fast* Cold Relief . Among oral products. Use as directed.
  • Our severe Cold Day and Night medicine provides fizzy fast daytime relief of nasal & sinus congestion, cough, headache, fever, sore throat and body aches & pains. Provides nighttime relief of: nasal congestion, sinus pressure & congestion, sneezing, runny nose, cough, headache, fever, sore throat and body aches & pains.
  • Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.
  • Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go.
  • Comes in Effervescent form, with a refreshing Citrus (day) & Lemon (night) flavor. Use as directed.

Description

Alka-Seltzer Plus Cold medicine Day and Night Effervescent Tablets dissolve quickly in hydrating water and are instantly ready to start working whether you need it during the day or at night. Each dose is individually wrapped and transforms in just 4oz of water into a liquid-fast medicine. After you drink the refreshing, sparkling solution, Alka-Seltzer Plus works quickly to relieve your worst cold symptoms. In one convenient package you get daytime relief from: Nasal & Sinus Congestion, Cough, Sore Throat, Fever, Headache and Body Aches & Pains and nighttime relief from: Cough, Sneezing, Runny Nose, Sore Throat, Nasal Congestion, Sinus Congestion & Pressure, Fever, Headache and Body Aches & Pains
Suggested Age: 12 Years and Up
Product Warning: Consult a doctor if you have liver disease
Product Form: Dissolving Tablet
Primary Active Ingredient: Aspirin
Package Quantity: 24
Net weight: .23 Pounds
TCIN: 88824900
UPC: 016500598879
Item Number (DPCI): 094-14-3268
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

aspirin (nsaid)(325mg), dextromethorphan hydrobromide(10mg), phenylephrine bitartrate(7.8mg). aspirin (nsaid)(325mg), chlorpheniramine maleate(2mg), dextromethorphan hydrobromide(10mg), phenylephrine bitartrate(7.8mg).

Purpose

Pain Reliever/Fever Reducer, Cough Suppressant, Nasal Decongestant.. Pain Reliver/Fever Reducer, Antihistamine, Cough Suppressant, Nasal Decongestant..

Uses

minor aches and pains, headache, cough, sinus congestion and pressure, nasal congestion, sore throat., minor aches and pains, headache, runny nose, sinus congestions and pressure, cough, sneezing, sore throat, nasal congestion.

Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you

Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you: are age 60 or older,have had stomach ulcers or bleeding problems,take a blood thinning (anticoagulant) or steroid drug,take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others),have 3 or more alcoholic drinks every day while using this product,take more or for a longer time than directed.

Do not use

Do not use: if you are allergic to aspirin or any other pain reliever/fever reducer,if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product,if you have ever had an allergic reaction to this product or any of its ingredients,in children under 12 years of age.

Ask a doctor before use if

Ask a doctor before use if: stomach bleeding warning applies to you,you have a history of stomach problems, such as heartburn,you have high blood pressure, heart disease, liver cirrhosis, or kidney disease,you are taking a diuretic,you have asthma; diabetes; thyroid disease; glaucoma; cough that occurs with excessive phlegm (mucus); a breathing problem such as emphysema or chronic bronchitis; difficulty in urination due to enlargement of the prostate gland; persistent or chronic cough such as occurs with smoking, asthma, or emphysema; a sodium-restricted diet.

Ask a doctor or pharmacist before use if you are

Ask a doctor or pharmacist before use if you are: taking a prescription drug for gout; diabetes; arthritis,taking sedatives or tranquilizers.

When using this product

When using this product: do not exceed recommended dosage,may cause marked drowsiness,avoid alcoholic drinks,alcohol, sedatives, and tranquilizers may increase drowsiness,be careful when driving a motor vehicle or operating machinery,excitability may occur, especially in children.

Stop use and ask a doctor if

Stop use and ask a doctor if: an allergic reaction occurs. Seek medical help right away,you experience any of the following signs of stomach bleeding; feel taint; vomit blood; have bloody or black stools; have stomach pain that does not get better,pain, cough, or nasal congestion gets worse or lasts more than 7 days,fever gets worse or lasts more than 3 days,redness or swelling is present,new symptoms occur,ringing in the ears or loss of hearing occurs,cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition,nervousness, dizziness, or sleeplessness occurs.

Directions

Do not take more than the recommended dose. Do not take the Day and Night products at the same time; wait 4 hours after taking the last Night dose before taking the Day product., Do not take more than the recommended dose. Do not take the Day and Night products at the same time; wait 4 hours after taking the last Day dose before taking the Night product.

Adults and Children 12 Years and Over

Take 2 tablets fully dissolved in 4 oz of water every 4 hours. Do not exceed 4 tablets in 12 hours or as directed by a doctor.

Children Under 12 Years

Do not use.

Adults and Children 12 Years and Over

Take 2 tablets fully dissolved in 4 oz of water every 4 hours. Do not exceed 4 tablets in 12 hours or as directed by a doctor.

Children Under 12 Years

Do not use.

Other information

Each tablet contains: potassium 80 mg; sodium 356 mg. Store at room temperature. Avoid excessive heat., Each tablet contains: potassium 80 mg; sodium 356 mg. Store at room temperature. Avoid excessive heat.

Inactive ingredients

anhydrous citric acid, calcium silicate, dimethicone, fd&c red #40, fd&c yellow #6 , flavor, mannitol, potassium bicarbonate, povidone, sodium bicarbonate, sucralose, anhydrous citric acid, calcium silicate, dimethicone, flavor, mannitol, potassium bicarbonate, povidone, sodium bicarbonate, sucralose

Question or comments?

800-986-0369., 800-986-0369

Shipping details

Estimated ship dimensions: 3.94 inches length x 3.15 inches width x 2.02 inches height
Estimated ship weight: 0.19 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Related Categories

4.7 out of 5 stars with 139 reviews
quality: 4.75 out of 5
value: 4.58 out of 5
93% would recommend
15 recommendations
5 out of 5 stars
22 July, 2025
originally posted on influenster.com
Image

Convenient cold relief combo for day and night wit

tried Alka-Seltzer Plus Severe Day + Night Cold tablets when I needed extra comfort during seasonal changes. I liked the fizzy action — it dissolved quickly and was easy to drink. The taste was a bit strong but manageable. I used the day and night versions separately and appreciated having a set that fits both times of day. The packaging was easy to understand, and the individual doses were convenient to carry. I would consider keeping this on hand again.
irinan31_2859
Did you find this review helpful?
5 out of 5 stars
16 July, 2025
originally posted on influenster.com
Image

So good

This is my go too when sick makes me feel so much better and work super quick easy to Travel with smell is refreshing definitely worth the buy for when sick easy to grab
taylorm858_2062
Did you find this review helpful?
4 out of 5 stars
Thumbs up graphic, would recommend
3 July, 2025

Tastes disgusting & weird effects but works

Oh my god. These taste disgusting. The aftertaste is awful, do not take it with water. The first time I tried with water I literally couldn’t take more than a few sips. I tried using apple juice and it was a bit better but I still had to chug it to get through. The day ones made me feel insane. Almost immediately I started feeling light headed and a little out of body and super jittery. It was like I was on something. It was a crazy feeling and freaked me out a little. I googled it and medicine like this (DayQuil etc) can have this side effect and it faded after some minutes. It definitely worked, I felt completely better and it lasted a while. Got rid of my sore throat and congestion for the day.
rosewater
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
30 March, 2025

Works great

This works great. Sure it doesn’t taste great but pinch your nose so you don’t taste it and you’ll feel well enough to go about your day.
CJPD
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
4 out of 5 stars
Thumbs up graphic, would recommend
29 January, 2025Verified purchase

good relief for symptoms, but the taste...

Both the day and the night flavors taste like you're drinking a melted-down PVC shower curtain
cr202
5 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
15 January, 2025Verified purchase

Life Saver!

This is a life saver! I had a cold chills and fever the whole day, I drank at night time. The next day I was able to go back to work like nothing happened! Don’t missed these out!
PD
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
4 January, 2025Verified purchase

Lifesaver

Has never failed me. Anytime I get sick or start to feel under the weather, this stuff has me back to my old self in no time. Tastes great and the carbonation sensation always helps with sore throats.
Target Guest
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
22 September, 2024Verified purchase

GO TO!

Works for me everytime and this product has never let me down.
dxo
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
17 February, 2024Verified purchase

Works

I feel like it helps with symptoms and works fast. Doesn’t taste like medicine.
Aims
value: 5 out of 5
quality: 5 out of 5
2 guests found this review helpful. Did you?
4 out of 5 stars
Thumbs up graphic, would recommend
21 January, 2024Verified purchase

Works great!

These work really well. I was trying to stop a cold in its tracks and every day that. I took these that is exactly what happened. I was having trouble getting them to completely dissolve. It seemed like there was always a little bit at the bottom of the glass that was really bitter and didn’t dissolve into the rest of the solution, but it didn’t bother me. I just added more water to my glass and tried to drink that too. I do not think the night time ones make me sleepy at all though so if you’re looking for something with a little more nighttime power I would pick something else.
Jackie Hullabaloo
value: 4 out of 5
quality: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
12 January, 2024

Helped a lot

This medicine works quickly and kept my cold at bay so I could focus and continue my day. I definitely felt a lot worse once the medicine wore off. Nighttime medicine helped my rest for 2 nights in a row. I'll keep this in my medicine cabinet.
Katharinejoan
quality: 5 out of 5
value: 5 out of 5
2 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
7 January, 2024Verified purchase

You will feel better

Best cold medicine Feel its effects immediately
MsDiggity
value: 5 out of 5
quality: 5 out of 5
Did you find this review helpful?
2 out of 5 stars
Thumbs down graphic, would not recommend
17 December, 2023Verified purchase

Ugh sinus pressure

Weak. Made symptoms worse
R P
value: 1 out of 5
quality: 2 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
8 December, 2023Verified purchase

Great product

Helps when you have sore throat. Would definitely recommend!
Susan
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
4 out of 5 stars
Thumbs up graphic, would recommend
7 December, 2023

Definitely works

It works great, always have, as a kid, it made me gag from the taste, but it's very effective, at least in my opinion, taste will never be good though.
Haley
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
6 December, 2023Verified purchase

Only stuff that helps

It helps me sleep when I have a cough.
lisawasheretoo
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
1 December, 2023Verified purchase

Favorite. Cols med

My favorite for colds
Chessdoc
value: 5 out of 5
quality: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
26 August, 2022
originally posted on influenster.com
Image

They work wonders

I wanted something that could help with the col I got today at work, and are glad I was able to get these since I started feeling better after the second dose unlikely others I have tried. These are easy to take and do its job.
julicasti85
1 guest found this review helpful. Did you?
5 out of 5 stars
30 March, 2022
originally posted on influenster.com
Image

Great

I swear, this is the best cold medication on the market. Whenever I use it, I feel so much better. My favorite thing about it is it really helps with a runny nose. Do yourself a favor and drop your other meds for this.
ashleyadams
Did you find this review helpful?
5 out of 5 stars
4 March, 2022
originally posted on influenster.com
Image

Number one go to

This product is our number one go to if we get sick enough to need medication. We like the effervescence and the day time non-drowsy with aspirin. The nighttime formula definitely helps with relaxing symptoms enough to get some rest.
bobbiejoi
Did you find this review helpful?

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