Sponsored
Depend Night Defense Adult Incontinence Underwear for Women - Overnight Absorbency - Blush
$52.99 ($1.32/count)
In Stock
Eligible for registries and wish lists
At a glance
Sponsored
About this item
Highlights
- DEPEND NIGHT DEFENSE: 40 count of Depend Night Defense Incontinence Underwear for Women, size extra-extra-large (55–64" waist)
- OVERNIGHT ABSORBENCY: Our adult diapers deliver up to 12 hours protection
- OVERNIGHT PROTECTION: Our women’s adult diapers feature a super absorbent core which absorbs 30x its weight*, locking away wetness for all-night comfort (*super absorbent material absorbs 30x its weight)
- ODOR CONTROL: Depend adult diapers for women are made with OdorBlock technology
- DRYNESS: Each disposable underwear wicks wetness away
- Depend incontinence and postpartum underwear for bladder leaks is HSA/FSA-eligible in the US (check with your provider for coverage details)
- Depend’s packaging and product may vary
Description
Sleep through the night with Depend Night Defense Incontinence Underwear for Women with Overnight Absorbency, providing up to 12 hours of protection. Available in a beautiful blush color, our adult diapers for women are ideal for incontinence, postpartum bladder leaks, and nighttime use. Our adult diapers for women features a super absorbent core that absorbs 30x its weight* and OdorBlock technology. Depend underwear wicks wetness away. Depend Night Defense incontinence and postpartum underwear for bladder leaks is available in five sizes: small (24–30" waist), size medium (31–37" waist), size large (38–44" waist), size extra-large (45–54" waist) and size extra-extra-large (55–64" waist). Packaging may vary from images shown. Some more good news: this product is HSA/FSA-eligible in the US – check with your provider for coverage details. (*super absorbent material absorbs 30x its weight)
Health Facts: No Fragrance Added
Disposability: Do not flush
Absorbency: Overnight
Package Quantity: 40
Number of units per package: 40
Minimum Waist Size: 55 Inches
Maximum Waist Size: 64 Inches
Features: Leak Protection, Nighttime Use, Disposable
TCIN: 87937523
UPC: 036000549362
Item Number (DPCI): 245-01-2919
Origin: Assem In USA w/ foreign parts
If the item details aren’t accurate or complete, we want to know about it.
Allergens & Warnings:
WARNING: TO AVOID DANGER OF SUFFOCATION, KEEP THIS PLASTIC BAG AWAY FROM BABIES AND CHILDREN. DO NOT USE THIS BAG IN CRIBS, BEDS, CARRIAGES OR PLAY PENS. LIKE MOST ARTICLES OF CLOTHING, UNDERWEAR CAN BURN IF EXPOSED TO FLAME OR OTHER SOURCE OF IGNITION., BLADDER INCONTINENCE MAY BE CAUSED BY A CONDITION THAT CAN BE MEDICALLY TREATED. PLEASE SEE YOUR DOCTOR FOR PROFESSIONAL ADVICE.Shipping details
Estimated ship dimensions: 12 inches length x 18.25 inches width x 8.938 inches height
Estimated ship weight: 7 pounds
We regret that this item cannot be shipped to PO Boxes.
This item cannot be shipped to the following locations: American Samoa (see also separate entry under AS), Guam (see also separate entry under GU), Northern Mariana Islands, Puerto Rico (see also separate entry under PR), United States Minor Outlying Islands, Virgin Islands, U.S., APO/FPO
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
Q: Is there a guide somewhere about sizes? Do I measure her waist? Go by pounds? Height and weight? How would I know whether to get her a small or a medium?
submitted by N - 4 years ago
A: the pictures of the product have a waist and pant size to figure out the size I wear a size 16 or 18 pant and use a size L in the Depends
submitted byme - 2 years agoA: Hi there, thank you for contacting us. You can visit our website to view our size guide to help determine the best size. We hope this helps!
submitted byDependExpert - 2 years agoBrand expert
Q: Do they have side panels that open to make them easier to remove
submitted by Lacicco - 1 year ago
A: They have a seam on the sides that can be torn open so yes
submitted byOhioscanner - 2 months agoA: They slid on and off, side panels do not open. I had a nurse that had suggested using scissors to cut sides for easier removal.
submitted byDelta - 1 year ago
Q: Are these indiviually wrapped, I.e. I desire to use during traveling.
submitted by InMyOpinionWisdom - 1 year ago
A: No, they are not. Hope this helps.
submitted byGreat purchase - 1 year agoA: No, but they are panties so it is ok to put them with Your other clothes. During travelling I wear only depends and not take any panties with me.
submitted byEmma - 1 year ago
Q: how many cups do they hold
submitted by Donna - 2 years ago
A: Hi Donna, our Depend® Night Defense® Underwear provides up to 12 hours of protection and can hold 25-30 ounces (up to 3.75 cups). Hope this helps!
submitted byDependExpert - 2 years agoBrand expertA: The night time type has a nice liner that protects from leaks. I wear them during the day too. They're especially nice when I have a cough and might leak quite a bit when I cough.
submitted byme - 2 years ago
Q: Can these be used for fecal incontinence? Do you know of anything that can?
submitted by MsAdventure - 3 years ago
A: Hi there. Our Depend® products are designed and tested for urinary incontinence, not bowel incontinence. Thank you for reaching out, and we hope this helps!
submitted byDependExpert - 3 years agoBrand expertA: I have both kinds of incontinence and these are as good as anything out there. I have tried lots of brands. Haven't found better. I wish.
submitted byOhioscanner - 2 months ago
Q: How do you know the design size such as brief, low cut, etc.?
submitted by Lesstressrx - 3 years ago
A: Hi Lesstressrx, our Night Defense Underwear is made with sureFit waistband for a comfortable underwear-like fit. It is the closets thing to real underwear you can buy. We hope this helps!
submitted byDependExpert - 3 years agoBrand expertA: Closer to brief. Depends on what size you get. If I get large they come under my belly button. XL comes over my belly button. I am size 18W, 2XL.
submitted byOhioscanner - 2 months ago
Q: I can’t clearly see the size equivalent images. Does size large really begin at 16? Are these American sizes?
submitted by SashasMum - 4 years ago
A: Thank you for your question. Our size large is for pant sizes 16-20. We hope this helps!
submitted byDependExpert - 4 years agoBrand expertA: Yes they are American sizes.
submitted byOhioscanner - 2 months ago
Q: I weigh 25 pounds. Not sure if I need small or medium
submitted by crystal ball - 7 months ago
A: These fit people over 100 pounds.
submitted byOhioscanner - 2 months ago
Q: are these one piece pull ups
submitted by rose - 8 months ago
A: Yes they are one piece pull ups
submitted byOhioscanner - 2 months ago
Q: Do these run small? My waist is 41” and weight 168. But I have a big belly. Should I buy L or XL? I checked website. There is absolutely no sizing information. I even tried a search on the site but nothing came up
submitted by tlblack - 11 months ago
A: A large would still be fine! I’m a size 14-16 in pants and I use the large and have an apron belly!
submitted byAnonymous - 10 months ago
Depend Women's Collection
About the collection
Depend Incontinence Underwear for Women: Depend is helping people manage their bladder leakage for more than 35 years and get back to what matters most. Feel confident with Depend Fit-Flex—protective, disposable underwear for everyday bladder incontinence and surprise postpartum leaks. And say goodbye to bulky adult diapers by saying hello to maximum-absorbency Depend Silhouette, featuring super premium shapewear fabric for invisible comfort and protection. Plus, rest easy with Depend Night Defense, bladder leakage underwear that offers overnight absorbency. Explore our collection for more!
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4.5 out of 5 stars with 2376 reviews
comfort: 4.57 out of 5
effectiveness: 4.46 out of 5
quality: 4.43 out of 5
value: 4.2 out of 5
84% would recommend
107 recommendations
1 out of 5 stars
Thumbs down graphic, would not recommend
18 October, 2025Verified purchase
It did not work for me -
It did not perform as others I’ve had
1 reply from DependExpert team - 3 days ago
We appreciate you sharing your review. If you'd like to share more details, please give us a call at: 1-877-413-3736 (Monday–Friday from 8am-5pm CT). We look forward to speaking with you.
5 out of 5 stars
8 October, 2025
originally posted on influenster.com
The best
[This review was collected as part of a promotion.] The best underwear for women! There’s no odor, extremely comfortable and very absorbent. They are durable and fit very comfortably. I love them!!
5 out of 5 stars
Thumbs up graphic, would recommend
7 October, 2025Verified purchase
Mr
Best cost we have found locally, with our Circle membership. A definite reason we shop at Target!
4 out of 5 stars
28 September, 2025
originally posted on influenster.com
Absorbent
[This review was collected as part of a promotion.] I wore this at night due to waking up with urgency. These did the job they were supposed to do but were a little uncomfortable. I think for me it would be better in the next size up.
2 out of 5 stars
Thumbs down graphic, would not recommend
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Way to thick
They are not like 4 years ago just small all different colors. These are so bulky in crotch it causes bunch up in behind
5 out of 5 stars
21 September, 2025
originally posted on influenster.com
Awesome Absorbency
[This review was collected as part of a promotion.] My elderly grandmother uses these as she has difficulty making it to the bathroom. The material is thin and flexible as to not make her uncomfortable when she is wearing them. They fit snugly against her body which is helpful to avoid leakage. So far we haven’t had any issues with them tearing so they seem pretty durable. These have wonderful absorbency as you can see in the video. I poured a cup of water in them which disappeared almost instantly. This is very helpful to control odor. Overall, the night defense underwear serve their purpose and a great for people struggling with bladder control.
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21 September, 2025
originally posted on influenster.com
Good to wear comfort and last long.
[This review was collected as part of a promotion.] I love wearing this underwears when i go on a trip it helps a lot it doesn't release an odor. its fit good an very absorben and it last a while. I really recommend it.
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originally posted on depend.com
Leakage Issues
I have been buying the Depend Night Defense Underwear for Women for many years & I have noticed within the last 6 times that I purchased the Nightly Depends do not last more than 4-5 hours @ night. I just wonder if the manufacturer of Depends is going to different materials & products because of the leakage in the Depends. I do not drink anything but water @ night & still has this leakage problem. Thank goodness I put a cover in my bed to keep my sheets dry. But, my gown is wet because of the nightly depend for women leaks big time.
1 reply from Depend Customer Service team - 1 month ago
Thanks for letting us know you had this experience. We always want you to feel protected and confident when wearing our products and we'd like to learn more to see how we can help. Please give us a call at 1-877-413-3736 (Monday–Friday from 8am-5pm CST). We hope to hear from you soon.
3 out of 5 stars
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originally posted on influenster.com
Good option
[This review was collected as part of a promotion.] I forgot I was getting these until they showed up at my door! There hasn’t been a reason to need them yet, however they are very soft and cute. The “ruffle” look on the side isn’t the most discrete if your pants are fitted. Overall they seem like a great option
5 out of 5 stars
2 September, 2025
originally posted on influenster.com
Discreet with no leaks!
[This review was collected as part of a promotion.] I have struggled with slight incontinence after having my 3rd baby, and these are so comfortable and leave no leaks! They are super discreet and are easy on/easy off. They are great for overnight protection.
4 out of 5 stars
28 August, 2025
originally posted on influenster.com
Adult briefs
[This review was collected as part of a promotion.] Well absolving adult briefs. The absorbency, odor, and comfort were spot on. However the fit seems to be on the smaller size. I would size up before purchasing again.
4 out of 5 stars
24 August, 2025
originally posted on influenster.com
Hard but still good
[This review was collected as part of a promotion.] For the absorbency is very good. The size is fitted on me. Easy to use. But the material is little hard so make feelittle hot too. This one stop the odor very good
5 out of 5 stars
23 August, 2025
originally posted on influenster.com
Affordable and comfortable!
[This review was collected as part of a promotion.] Great product! Very soft and comfortable and I love the way it stretches, making them fit nicely and very durable to wear throughout the night! Definitely recommend if you are trying to find the right product.
5 out of 5 stars
23 August, 2025
originally posted on influenster.com
Great overnight protection that’s comfortable, dis
[This review was collected as part of a promotion.] I was impressed with how absorbent these are overnight. They provide reliable protection without leaks, and I appreciate the soft material that makes them comfortable to wear. The fit is secure yet not too tight, and I noticed that they control odor well, which adds peace of mind. They are also discreet under pajamas and don’t make any noise when moving. Overall, they are durable, effective, and help me sleep worry-free.
5 out of 5 stars
21 August, 2025
originally posted on influenster.com
I love the way they fit
[This review was collected as part of a promotion.] The fit was wonderful and amazing. Durability and absorbency and odor control were under control. The comfort was my favorite. The fit was my ideal size.
5 out of 5 stars
21 August, 2025
originally posted on influenster.com
yes
[This review was collected as part of a promotion.] these are great. large and good for a variety of body types. good to have for women who need comfort and durability. a great product by a good brand.
5 out of 5 stars
19 August, 2025
originally posted on influenster.com
The Night Defense Underwear for women are very com
[This review was collected as part of a promotion.] The Depend Night Defense Underwear for women are very comfortable with a nice fit. They’re very durable and absorbent for night wear and also controls odor.
4 out of 5 stars
18 August, 2025
originally posted on influenster.com
Soft material
[This review was collected as part of a promotion.] These ended up being used by a family member. They said they work great, and fit true to size. They have a stretchy waist band so they don't fit too tight. The pad inside of them is thick.
5 out of 5 stars
15 August, 2025
originally posted on influenster.com
🥰🤩🤩
[This review was collected as part of a promotion.] This product offers a reliable solution for those seeking overnight protection from bladder leaks. With a medium size designed specifically for comfort, the underwear features a soft, discreet fit that allows for natural movement. It is disposable, which adds convenience for overnight use. Each pack contains 15 pairs, providing ample supply for multiple nights. The absorbent core is designed to handle overnight incidents, giving users peace of mind during sleep. The blush color adds a touch of understated style, making it a more appealing option compared to traditional incontinence products. Overall, this product combines functionality and comfort, making it a practical choice for women needing extra support during the night.
5 out of 5 stars
14 August, 2025
originally posted on influenster.com
Protection at best
[This review was collected as part of a promotion.] Wow these are great. I have an overactive bladder and these keep me dry and fit great. Very comfortable and can wear them with anything. Keeps odor away and are very durable