Sponsored
Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency
$56.99 ($0.89/count)
In Stock
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At a glance
Sponsored
About this item
Highlights
- DEPEND NIGHT DEFENSE: 64 count of Depend Night Defense Adult Incontinence Underwear for Men, size small/medium (26–34" waist)
- OVERNIGHT ABSORBENCY: Our adult diapers deliver up to 12 hours protection
- OVERNIGHT PROTECTION: Our men’s adult diapers feature a super absorbent core which absorbs 30x its weight*, locking away wetness for all-night comfort (*super absorbent material absorbs 30x its weight)
- ODOR CONTROL: Depend adult diapers for men are made with OdorBlock technology
- DRYNESS: Each disposable underwear for bladder leaks wicks wetness away
- Depend incontinence underwear for men is HSA/FSA-eligible in the US (check with your provider for coverage details)
- Depend’s packaging and product may vary
Description
Sleep through the night with Depend Night Defense Incontinence Underwear for Men with Overnight Absorbency, providing up to 12 hours of protection. Available in a classic grey color, our adult diapers for men are ideal for bladder incontinence for nighttime use. Our men’s incontinence underwear for bladder leaks features a super absorbent core that absorbs 30x its weight* and OdorBlock technology. Depend underwear wicks wetness away. Depend Night Defense incontinence underwear for men is available in three sizes: size small/medium (26–34" waist), size large (35–43" waist) and size extra-large (44–54" waist). Packaging may vary from images shown. Some more good news: this product is HSA/FSA-eligible in the US – check your provider for coverage details. (*super absorbent material absorbs 30x its weight)
Health Facts: No Fragrance Added
Disposability: Do not flush
Absorbency: Overnight
Package Quantity: 64
Number of units per package: 64
Minimum Waist Size: 26 Inches
Maximum Waist Size: 34 Inches
Features: Leak Protection, Nighttime Use, Disposable
TCIN: 87937520
UPC: 036000551594
Item Number (DPCI): 245-01-0042
Origin: Assem In USA w/ foreign parts
If the item details aren’t accurate or complete, we want to know about it.
Allergens & Warnings:
WARNING: TO AVOID DANGER OF SUFFOCATION, KEEP THIS PLASTIC BAG AWAY FROM BABIES AND CHILDREN. DO NOT USE THIS BAG IN CRIBS, BEDS, CARRIAGES OR PLAY PENS. LIKE MOST ARTICLESOF CLOTHING, UNDERWEAR CAN BURN IF EXPOSED TO FLAME OR OTHER SOURCE OF IGNITION.Shipping details
Estimated ship dimensions: 12 inches length x 18 inches width x 10.625 inches height
Estimated ship weight: 9.4 pounds
We regret that this item cannot be shipped to PO Boxes.
This item cannot be shipped to the following locations: American Samoa (see also separate entry under AS), Guam (see also separate entry under GU), Northern Mariana Islands, Puerto Rico (see also separate entry under PR), United States Minor Outlying Islands, Virgin Islands, U.S., APO/FPO
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
Q: Can these be worn all day
submitted by Nana - 3 years ago
A: Hi Nana, our Night Defense Underwear provides protection from bladder leaks for up to 12 hours. We hope this helps!
submitted byDependExpert - 3 years agoBrand expertA: yes it can . it obsorbs a lot of urine.
submitted bydiaper boy - 2 years ago
Q: Will this product help with absorbtion of urine if sleeping on back?
submitted by Grandma G - 29 days ago
A: Thanks for your question. Yes, Night Defense® Underwear for Men are designed for more leakage coverage while lying down. It also offers nighttime protection from urinary leaks for up to 12 hours and features form-fitting leg elastics for a discreet fit under pajamas.
submitted byDependExpert - 28 days agoBrand expert
Q: Has the absorpency formula for the Night Defense Depense been changed recently? My husband has had, within the past 2 months, multiple leaking issues with this product.
submitted by Caretaker Wife - 4 months ago
A: We're sorry to hear about your husband's recent experience with our Depend Night Defense Underwear. We'd like the opportunity to learn more to see how we can help. Please give us a call at 1-877-413-3736 (Monday–Friday from 8am-5pm CST). We hope to hear from you soon.
submitted byDependExpert - 4 months agoBrand expert
Q: Will the diaper contain bowel incontinence
submitted by Tony - 9 months ago
A: Hi Tony. Our Depend® products are designed and tested for urinary incontinence, not bowel incontinence. Thank you for reaching out, and we hope this helps!
submitted byDependExpert - 9 months agoBrand expert
Q: What is the proper way to put on night defense depends
submitted by Max - 10 months ago
A: Hi Max! Depend Night Defense is designed to look and feel like underwear. They do not have tape fasteners, so you can easily slip them on.
submitted byDependExpert - 10 months agoBrand expert
Q: i want to order 7 of these diapers plus CaDCADE DISHWASHING DETERGENT
submitted by MARGARET - 3 years ago
A: Hi MARGARET, please reach out to Target directly for the best assistance at 1 (800) 440-0680. Thank you.
submitted byDependExpert - 3 years agoBrand expert
Q: what size depends for 38" waist
submitted by OZ - 4 years ago
A: Thank you for your question. Our Depend Night Defense in size large is for pant sizes 35-43. We hope this helps!
submitted byDependExpert - 4 years agoBrand expert
Q: what is the waist size for S/M?
submitted by JCLAYTON - 4 years ago
A: Thanks for your question. The waist measurements for our S/M underwear is 31-37in. We hope this helps.
submitted byDependExpert - 4 years agoBrand expert
Depend Incontinence Essentials for Men Collection
About the collection
Depend Incontinence Essentials for Men
Depend is helping people get back to what matters most. Feel confident with Depend Fit-Flex—protective, disposable underwear for everyday bladder incontinence. Manage bladder leaks big and small with maximum-absorbency pads, Depend Guards, and light-absorbency pads, Depend Shields. Say goodbye to bulky adult diapers and say hello to Depend Real Fit, Depend men's softest, smoothest underwear. Plus, rest easy with Depend Night Defense, bladder leakage underwear that offers overnight absorbency. Explore our collection for more!
Depend is helping people get back to what matters most. Feel confident with Depend Fit-Flex—protective, disposable underwear for everyday bladder incontinence. Manage bladder leaks big and small with maximum-absorbency pads, Depend Guards, and light-absorbency pads, Depend Shields. Say goodbye to bulky adult diapers and say hello to Depend Real Fit, Depend men's softest, smoothest underwear. Plus, rest easy with Depend Night Defense, bladder leakage underwear that offers overnight absorbency. Explore our collection for more!
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4.5 out of 5 stars with 884 reviews
comfort: 4.4 out of 5
effectiveness: 4.18 out of 5
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80% would recommend
62 recommendations
5 out of 5 stars
5 October, 2025
originally posted on depend.com
Great products
Very comfortable, no leaks as they promise and blocks the odor.
5 out of 5 stars
Thumbs up graphic, would recommend
22 September, 2025
Depend Night Defense Briefs
Excellent absorbency and so comfortable.
1 out of 5 stars
16 September, 2025
originally posted on depend.com
Leak a lot and not as described
These are described as non leaking but they indeed leak through the leg openings and through the back. The back doesn't have anything to absorb urine, so its a prime spot for leaking and wetting the bed. My 89 year old father wears these and I have to get up during the night to change him because they leak. I have sized him correctly based on his weight and waste. I was very disappointed. I wont be buying these again for night use.
1 reply from Depend Customer Service team - 1 month ago
We're sorry to hear about your father's recent experience with our Depend Underwear. We'd love the chance to learn more to see how we can help. Please give us a call at 1-877-413-3736 (Monday–Friday from 8am-5pm CST). We hope to hear from you soon.
5 out of 5 stars
15 September, 2025
originally posted on influenster.com
Very dependable.
[This review was collected as part of a promotion.] Very dependable. Work great not leaks. Able to wear all day wile driving long distance with no leaks. Very comfortable. Order control. I drive a truck long hauls with very few stops.
2 out of 5 stars
30 August, 2025
originally posted on depend.com
Rear coverage is bad
[This review was collected as part of a promotion.] Poor rear coverage. The waist band fit but the back is way to short for nighttime.
1 reply from Depend Customer Care Team team - 2 months ago
Hi Larry, thanks for letting us know you had this experience. We always want you to feel protected and confident when wearing our products and we'd like to learn more to see how we can help. Please give us a call at 1-877-413-3736 (Monday–Friday from 8am-5pm CST). We hope to hear from you soon.
1 out of 5 stars
10 August, 2025
originally posted on depend.com
Did not hold up
Felt good, good fot. Comfortable, but it leaked after just normal during the night. Had to get up out of bed and remove it. The next night same thing.!!
1 reply from Depend Customer Care Team team - 2 months ago
We're sorry to hear about your recent experience with our Depend Underwear. We wouldn't expect this to happen, and would like the opportunity to learn more to see how we can help. Please give us a call at 1-877-413-3736 (Monday–Friday from 8am-5pm CST). We hope to hear from you soon.
5 out of 5 stars
3 August, 2025
originally posted on influenster.com
You'll never have an issue with these
[This review was collected as part of a promotion.] Depends, nighttime, defense underwear are very comfortable. They are leak proof the leak protection is very well, especially when slight leaks haven't at night. The abnorbincy is very good to where you do not feel any witness if you have leak issues. There is no odor whether you have number one or number 2.They are very very comfortable and not noticeable through clothes When looking for a pair Depends that fit well.These fit very comfortably and there is no Issue with moving around they are Very comfortable.I recommend these to anybody.I know that hasn't issued at night time while they sleep
5 out of 5 stars
29 July, 2025
originally posted on influenster.com
fit
[This review was collected as part of a promotion.] I recently purchased the Depend Fresh Protection Night Defense Underwear, and I’m extremely satisfied with its performance. The product is very comfortable to wear and fits securely without feeling bulky. I appreciate the soft material that doesn’t irritate the skin, making it perfect for overnight use. The DryShield technology truly delivers up to 12 hours of reliable protection, which helps me feel confident and worry-free throughout the night. I also noticed that it controls odors effectively, a feature that makes a big difference. The sizing is accurate, and the waistband stays in place without digging in. With 16 underwear per pack, it’s a great value for the quality and peace of mind it provides. Highly recommended for dependable nighttime protection.
4 out of 5 stars
23 July, 2025
originally posted on influenster.com
Good for overnight protection
[This review was collected as part of a promotion.] These were used for overnight protection, and they do a decent job. The fit is ok but since I just wore them over night and not all day long, it was fine. The material is nice tho. They handle a full wetting mostly if you are on your back. If they shift around or you’re in a different position they could leak. Odor control is good and they don’t make a lot of noise like you’d expect.
5 out of 5 stars
18 July, 2025
originally posted on influenster.com
Depend® Night Defense® provides exceptional overni
[This review was collected as part of a promotion.] have been thoroughly impressed with the performance of Depend® Night Defense® Underwear for Men. The product offers reliable overnight protection with excellent absorbency, keeping the skin dry and comfortable throughout the night. The fit is secure without being restrictive, and the material feels soft against the skin. I also appreciate the effective odor control, which adds an extra level of confidence. Most importantly, the underwear provides strong leak protection, even during long hours of use. It’s a dependable solution for anyone managing incontinence issues, ensuring both comfort and peace of mind.
4 out of 5 stars
14 July, 2025
originally posted on influenster.com
Comfortable and absorbant
[This review was collected as part of a promotion.] This underwear has a waistband that fits securely. They are a light gray color and are very absorbant. There is space at the gusset so that the underpants don't touch skin. It's really easy to dispose of them and replace.
4 out of 5 stars
12 July, 2025
originally posted on influenster.com
Comfortable and snug fit
[This review was collected as part of a promotion.] I recently tried Depends Might Defense disposable underwear. I used them to wear to bed at night for added protection and comfort. The large fit very comfortable and snug. I would highly recommend them.
5 out of 5 stars
10 July, 2025
originally posted on influenster.com
They work perfectly , and if you do happen to mess
[This review was collected as part of a promotion.] Midnight leakers rejoice, this product has you covered with its patented leak protection and the fit is perfect every time . They are comfortable so you can sleep all night and have no fear, the absorbency is perfect! Also don’t worry, they have excellent odor control so you can use them without fear of someone smelling you.
5 out of 5 stars
10 July, 2025
originally posted on influenster.com
Comfortable and leak protection
[This review was collected as part of a promotion.] Fit was great. Depend Night Defense underwear hits all the requirements: comfort, absorbency, leak protection and odor control. Happy to find this product at my local store.
3 out of 5 stars
Thumbs down graphic, would not recommend
9 July, 2025Verified purchase
Cant they make them WHITE or a LIGHTER color??
These Depends are too dark in color when a patient or any individual for that matter, is wearing light colored clothes. What happened to white ones?? My patient insisted on beige-white shorts but you can see the gray Depends thru the shorts. I could not find white ones that were PULL-UPS. So what's the problem with the dark colors. It's very troubling when someone makes fun of seeing his Depends.
5 out of 5 stars
9 July, 2025
originally posted on influenster.com
If you have frequent accidents it is good to have
[This review was collected as part of a promotion.] I was on road trip luckily I was wearing depends. They are leak proof, absorbing and no odor. Depends are very comfortable to wear almost like having on underwear.
4 out of 5 stars
7 July, 2025
originally posted on influenster.com
Sleep with peace of mind with these comfortable, a
[This review was collected as part of a promotion.] If one is in need of overnight protection, look no further than these. They fit as expected, are comfortable enough to forget you are wearing them, and can absorb a good amount.
5 out of 5 stars
7 July, 2025
originally posted on influenster.com
Nighttime personal dependable assurance
[This review was collected as part of a promotion.] Depend Nighttime is a great product for peace of mind. Depend Nightime is a comfortable fit with great absorption, preventing leaks, and hardly any odor. A very effective product
5 out of 5 stars
7 July, 2025
originally posted on influenster.com
Review of Night Defense Underwear for Men
[This review was collected as part of a promotion.] I was really impressed with the Night Defense Underwear for Men. They fit well and are incredibly comfortable to sleep in. To give a thorough and honest review, I even tested them by wetting them intentionally (as I didn't experience an accident during my use). I’m happy to report that they were very absorbent and kept moisture away from my skin. There was absolutely no leakage, and surprisingly, they didn’t have any unpleasant odor either. Overall, I feel much more at ease knowing that I have reliable protection in case of an accident. I would highly recommend these for anyone looking for peace of mind and comfort throughout the night!
4 out of 5 stars
6 July, 2025
originally posted on influenster.com
Surprisingly comfortable
[This review was collected as part of a promotion.] The elastic waistband is soft albeit a little long. But you can roll it down. Absorbing pad is more than sufficient. While it seems bulky at first it forms nicely after minimal wear and walking. Great option!