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Diphenhydramine HCl Nighttime Sleep Aid Liquid - Berry - 12 fl oz - up&up™ - 2 of 4Diphenhydramine HCl Nighttime Sleep Aid Liquid - Berry - 12 fl oz - up&up™ - 3 of 4Diphenhydramine HCl Nighttime Sleep Aid Liquid - Berry - 12 fl oz - up&up™ - 4 of 4
Diphenhydramine HCl Nighttime Sleep Aid Liquid - Berry - 12 fl oz - up&up™ - 1 of 4

Diphenhydramine HCl Nighttime Sleep Aid Liquid - Berry - 12 fl oz - up&up™

$7.39

In Stock

Eligible for registries and wish lists

At a glance

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About this item

Highlights

  • Compare to Vicks ZzzQuil active ingredient.
  • Non-habit forming sleep-aid.
  • Relieves occasional sleeplessness and helps you fall asleep.
  • For adults and children ages 12 years and over
  • Features a tasty mixed berry flavor. Gluten free.

Description

Compare to Vicks ZzzQuil active ingredient. Catch some Z's with Up&Up Night Time Sleep-Aid Liquid, Mixed Berry Flavor. Up&Up Night Time Sleep-Aid Liquid relieves occasional sleeplessness and helps you fall asleep. This night time sleep medicine contains the active ingredient diphenhydramine HCl 50 mg per 30 mL, the number one doctor recommended sleep-aid active ingredient (of U.S. physicians surveyed by an independent market research firm). Non-habit forming liquid sleep-aid. Dosing cup provided. For adults and children 12 years and over. Gluten free. Not for treating colds or the flu.
Suggested Age: 12 Years and Up
Health Facts: Aspirin-Free, Contains Diphenhydramine HCl
Active Ingredient Strength Value: 50 Milligrams
Product Warning: Consult a doctor if you are pregnant or nursing, consult a doctor if you have glaucoma, use caution while operating machinery, not for children under the age of 12, consult a doctor if you have heart disease, do not use with other drugs that cause drowsiness, consult a doctor if you have a breathing problem, use caution while driving a motor vehicle, ask a doctor if you have prostate issues, do not use with other diphenhydramine products
Product Form: Liquid
Primary Active Ingredient: Diphenhydramine
Includes: Sleeping Aid
Package Quantity: 1
Net weight: 12 fl oz (US)
TCIN: 14524598
UPC: 370030275809
Item Number (DPCI): 094-01-0778
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

diphenhydramine hcl' '50.0mg

Purpose

Nighttime sleep-aid

Uses

for the relief of occasional sleeplessness reduces time to fall asleep if you have difficulty falling asleep

Directions

take only one dose per day (24 hours) only use the dose cup provided adults & children 12 yrs & over children under 12 yrs 30 mL at bed time if needed or as directed by a doctor do not use

Other information

each 30 mL contains: sodium 20 mg store at 20-25°C (68-77°F)

Inactive ingredients

,,, alcohol, anhydrous citric acid, fd&c blue #1, fd&c red #40, flavor, high fructose corn syrup, poloxamer 407, propylene glycol, purified water, saccharin sodium, sodium benzoate, sodium citrate' '

Shipping details

Estimated ship dimensions: 2.38 inches length x 2.47 inches width x 7.24 inches height
Estimated ship weight: 1.03 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Q: What is the active ingredient in this sleep aid?

submitted by AI Shopping Assistant - 9 days ago
  • A: The active ingredient is Diphenhydramine HCl, with a strength of 50 milligrams per 30 mL.

    submitted byAI Shopping Assistant - 9 days ago
    Ai generated

Q: What flavor is the sleep aid liquid?

submitted by AI Shopping Assistant - 9 days ago
  • A: The sleep aid liquid features a tasty mixed berry flavor.

    submitted byAI Shopping Assistant - 9 days ago
    Ai generated

Q: Can this product be used for treating colds or flu?

submitted by AI Shopping Assistant - 9 days ago
  • A: No, this product is not intended for treating colds or the flu.

    submitted byAI Shopping Assistant - 9 days ago
    Ai generated

Q: Is this sleep aid suitable for children under 12?

submitted by AI Shopping Assistant - 9 days ago
  • A: No, this sleep aid is not suitable for children under the age of 12.

    submitted byAI Shopping Assistant - 9 days ago
    Ai generated

Q: Does this product contain gluten?

submitted by AI Shopping Assistant - 9 days ago
  • A: No, this sleep aid is gluten-free, making it suitable for those with gluten sensitivities.

    submitted byAI Shopping Assistant - 9 days ago
    Ai generated

Q: Does this contain alcohol?

submitted by Carolina - 6 years ago
  • A: Hi, thank you for your question about the Diphenhydramine Nighttime sleep aid. This product contains Ethyl Alcohol. If you would like additional information, please let us know and we would be happy to further assist you.

    submitted bythe Supplier - 6 years ago
    Brand expert

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Guests are saying

This sleep aid has garnered attention for its effectiveness in helping guests fall asleep and stay asleep throughout the night. Many appreciate its affordability compared to name-brand alternatives, making it a popular choice for those struggling with insomnia. However, recent formula changes and price fluctuations have raised concerns among guests. Despite these issues, the product remains a reliable option for those seeking a good night's rest without the grogginess often associated with other sleep aids.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.5 out of 5 stars with 482 reviews
    quality: 4.33 out of 5
    value: 4.04 out of 5
    75% would recommend
    70 recommendations
    5 out of 5 stars
    13 October, 2025Verified purchase

    Sleepy time

    This works better for me than many of the branded sleep aids. It’s more affordable and has a pleasant taste.
    Nai
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    12 October, 2025Verified purchase

    Just what i needed

    Works just as it’s supposed to-helps me fall asleep quickly but most importantly if I wake up in the middle of the night to use the bathroom I fall back asleep quickly. Usually my brain would turn on and I would be up just before my alarm goes off. This definitely helps me fall asleep.
    MTE
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    14 March, 2025Verified purchase

    Awesomd

    Works like a charm. I use this whenever I need a little help staying asleep. I don’t even need to drink the whole cup, a half does wonders.
    Charlie
    quality: 5 out of 5
    value: 5 out of 5
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    3 March, 2025Verified purchase

    It Works!

    Works great to fall asleep fast.
    MickMau
    quality: 5 out of 5
    value: 4 out of 5
    2 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    9 August, 2024Verified purchase

    New formula tastes terrible

    They unnecessarily changed the formula and now this tastes like cough syrup. So gross. Not to mention the severe price increase
    Frustrated
    quality: 1 out of 5
    value: 1 out of 5
    7 guests found this review helpful. Did you?
    4 out of 5 stars
    12 May, 2024Verified purchase

    Works well but photo is deceptive

    Photo is deceptive - you only receive one bottle, not two like all the photos depict Product itself works but the price fluctuates so you’re better off going to another store for a less expensive version.
    OC
    quality: 5 out of 5
    value: 3 out of 5
    4 guests found this review helpful. Did you?
    3 out of 5 stars
    11 May, 2024Verified purchase

    Error in Photo Deceptive

    Photo of product is of 2 bottles so I ordered 3 thinking I would receive 6 bottles total. I received only 3 single bottles. Picture misrepresents product.
    CL
    5 guests found this review helpful. Did you?
    4 out of 5 stars
    Thumbs up graphic, would recommend
    30 April, 2024Verified purchase

    Great Product - Pricing is Erratic

    The products works as promised. However, the pricing is the big issue. It was $4.99 for a long time. Then $5.99 - before going back down. Then it literally jumped overnight to $7.39 As of this writing (May, 2024) it is priced at $7.19 This has been a very frustrating experience. Why all of the changes all the time?
    Desert Dude
    quality: 4 out of 5
    value: 3 out of 5
    23 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    24 March, 2024Verified purchase

    Sleepy time

    A great product to help fall asleep, & sleep well through the night.
    Jzonagurl
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    29 February, 2024Verified purchase

    Love this product!

    This product works like a charm it is something I can always count on - never failed! I used to purchase it all the time when it was $4.99 and had to stop buying in the past because of price increase. So glad to see the price goes down again even though it's $5.99 now but still soooooo much better than $12.99 I'm really happy to be able to buy again. Thank you Target for listening to our voice :)
    Kelly8686
    quality: 5 out of 5
    value: 5 out of 5
    5 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    20 February, 2024Verified purchase

    It works!

    I'll start by saying item is $6 in my area and for the size and effectiveness I am fine paying that. Melatonin doesn't work for me. Zzzquil/NyQuil is too expensive and takes too long to kick and and the Great Value version makes me very groggy/irritable in the mornings. This is one so much better at making me sleepy. I will also mention I only use sleep aids 2-3 times a month so what works for me may not work for a more frequent user.
    Migonz12
    3 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    27 January, 2024Verified purchase

    Sleep Demons

    Granted it’s expensive but it does help keep my sleep demons away. I wake up a little groggy but nothing coffee can’t fix! Anything to stop flashbacks from 10 years ago. Thanks tarjay!
    Yummyicecoffee94
    quality: 5 out of 5
    value: 5 out of 5
    7 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    11 January, 2024Verified purchase

    Super Price Increase

    As a regular buyer of this product I was shocked that Target passed along a ridiculous price increase like they did over the past few months. There is no way that raw materials or shipping of this product have increased enought to warrant the new price. Shameful.
    Sleepy
    quality: 5 out of 5
    value: 1 out of 5
    16 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    1 January, 2024

    Ridiculous price increase

    Stop price gouging, this used to be $3 cheaper
    LH
    quality: 1 out of 5
    value: 1 out of 5
    16 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    31 December, 2023Verified purchase

    Good Nights Sleep

    I think this works as well but is way cheaper than the name brand.
    Her Mama
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    30 November, 2023Verified purchase

    Lost our business

    This was a low $4 and change and now almost $8 in a matter of a week. Yeah no thank you. The price hike is ridiculous.
    MrsUlate
    24 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    18 November, 2023Verified purchase

    Works great, price not a value anymore

    I love this stuff. I have the worse insomnia and nearly nothing has helped my condition. At a fraction of the cost of the name brand, this does it all. Taken 30 minutes before my bedtime, I started to feel my body and mind wind down. I am never groggy nor tired in the morning and am able to sleep through the night without awakening. The price has rose by $2.50 in the last couple months making almost that of the name brand.
    Angie DeVille
    value: 3 out of 5
    quality: 5 out of 5
    5 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    13 November, 2023Verified purchase

    Stop price gouging

    Good product but come on with the almost 3 dollar price increase. I’ll just buy name brand at this price.
    sunnyleeniles
    quality: 5 out of 5
    value: 1 out of 5
    18 guests found this review helpful. Did you?
    1 out of 5 stars
    2 November, 2023Verified purchase

    Price hike is crazy

    The price hike is crazy, might as well buy name brand. Was great for the old price now it’s just mid
    X
    value: 1 out of 5
    15 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    18 October, 2023Verified purchase

    Wow the price!!!

    Are you kidding me with this price hike? WHAT? It was a great price before, and now you will lose business for this price hiking.
    Not happy
    value: 1 out of 5
    quality: 1 out of 5
    18 guests found this review helpful. Did you?

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