Target New ArrivalsBack to SchoolCollegeClothing, Shoes & AccessoriesHome & DecorKitchen & DiningOutdoor Living & GardenGroceryHousehold EssentialsBabyBeautyPersonal CareSports & OutdoorsHealthWellnessSchool & Office SuppliesToys & GamesElectronicsVideo GamesMovies, Music & BooksParty SuppliesGift IdeasGift CardsPetsUlta Beauty at TargetShop by CommunityTarget OpticalDealsClearanceNew ArrivalsBack to SchoolCollegeTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Seed Daily Synbiotic Probiotic Capsules - 60ct - 2 of 4Seed Daily Synbiotic Probiotic Capsules - 60ct - 3 of 4Seed Daily Synbiotic Probiotic Capsules - 60ct - 4 of 4
Seed Daily Synbiotic Probiotic Capsules - 60ct - 1 of 4

Seed Daily Synbiotic Probiotic Capsules - 60ct

$59.99

In Stock

Eligible for registries and wish lists

At a glance

About this item

Highlights

  • DS-01® Daily Synbiotic is a 24-strain probiotic + prebiotic clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and strengthening the gut barrier.°
  • 60 vegan capsules (30 day supply). Take 2 capsules daily, with or without food. No refrigeration necessary. 53.6 billion AFU.
  • Proprietary ViaCap® technology safeguards probiotics through digestion to the colon for optimal results.°
  • 24 probiotic strains not found in most foods, yogurts, and beverages, and a polyphenol, non-fiber prebiotic from Indian pomegranate.
  • DS-01® has been validated in the largest clinical trial for a probiotic on bloating and gas in healthy adults°µ and studied in multiple randomized placebo control trials.
  • Extensively third-party tested for safety, strength, purity, heavy metals, pesticides, and allergens.
  • µAs of February 2026. In a randomized placebo-controlled trial on DS-01® Daily Synbiotic, n=350, Allegretti et. al, 2026.

Description

You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. The gut microbiome is connected to various organ systems and pathways throughout the body that are crucial for your health. In a healthy state, the gut microbiome carries out a multitude of functions like regulating digestion, enhancing nutrient absorption, and strengthening immune responses.

Seed’s flagship DS-01® Daily Synbiotic is a probiotic and prebiotic developed for whole body health, grounded in science with a deep understanding of the complex interactions within the microbiome. DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and strengthening the gut barrier.°

It contains 24 scientifically studied probiotic strains not commonly found in foods, yogurts, and beverages, and a polyphenolic, non-fiber prebiotic from pomegranate.

Proprietary capsule-in-capsule technology is intentionally engineered to safeguard probiotics through digestion, promoting survivability from stomach acid, digestive enzymes, moisture, and heat.*

Extensively third-party tested for safety, strength, purity, heavy metals, pesticides, and allergens.

Each jar contains 60 capsules, providing a 30-day supply of 53.6 billion AFU per dose with no refrigeration required.

*Based on a study conducted in SHIME®. Results may vary.
°These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Contains: Does Not Contain Any of the 9 Major Allergens
Suggested Age: 18 Years and Up
Product Warning: Consult a doctor if you are pregnant or nursing, keep out of reach of children
Product Form: Capsule
Package Quantity: 60
Colony forming units (billions): 0
Active fluorescent units (billions): 53.6
TCIN: 91816039
UPC: 860340001620
Item Number (DPCI): 094-02-5724
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Amount Amount Per Serving

% Daily Value*
Digestive Health Probiotic Blend 206mg
Micronutrient Synthesis Probiotic Blend 46mg
Dermatological Health Probiotic Blend 37mg
Cardiovascular Health Probiotic Blend 18mg
MAPP Microbiota-Accessible Polyphenolic Precursors 400mg
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

acid-resistant vegan outer [chlorophyllin] and inner [hypromellose, water] capsules, organic rice fiber, organic rice extract blend.

Allergens & Warnings:

If you are attempting to become, or are pregnant or nursing, consult your healthcare provider before use. Keep out of reach of children. Do not use if seal is broken.

Shipping details

Estimated ship dimensions: 2.87 inches length x 2.91 inches width x 3.45 inches height
Estimated ship weight: 0.54 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: I have diverticulosis would this help?

submitted by Yvette - 2 years ago
  • A: DS-01® Daily Synbiotic isn’t intended to treat, diagnose, prevent or cure any condition or disease, including diverticulosis. Therefore, we’re unable to comment on its safety, suitability, or efficacy in this specific context. For those with pre-existing conditions, we always suggest an informed conversation with a healthcare provider who may advise on the addition of DS-01® given your health history. For context, DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and supporting the gut barrier. If you’d like to learn more, you can check out our website or reach out directly.

    submitted bySeed Team - 2 months ago
    Brand expert

Q: Hard to swallow? I have problems with large caps and these look large.

submitted by Nansky - 2 years ago
  • A: Yes this is a big concern for me too hope you will show size of pill.

    submitted bystoragelessshopper - 1 year ago
  • A: I only swallow with food and these are not bad. Pretty standard size.

    submitted byFmz - 2 years ago
  • A: Thanks so much for your question! Our DS-01® Daily Synbiotic capsule is size 00—that’s 0.917 inches long with a diameter of 0.322 inches, to be exact. We wouldn't recommend opening or tampering with the DS-01® Daily Synbiotic capsules in any way, as our ViaCap® is especially designed to ensure the bacteria stay alive through digestion and make it to the colon. That said, you may certainly try experimenting with how you may be able to tolerate the capsules—any method in which you can preserve the 2-in-1 ViaCap® capsule would be perfectly fine. Please reach out to care@seed.com with any additional questions!

    submitted bySeed Team - 2 years ago
    Brand expert

Q: How many pills per day are recommended?

submitted by Judy - 5 months ago
  • A: The daily dosage for DS-01® is two capsules per day (which includes 53.6B AFU + 400mg Indian Pomegranate). DS-01® can be taken any time of day—consistent daily intake is most important. We generally recommend taking the capsules together, but feel free to space it out if that works better for your routine.

    submitted bySeed Team - 5 months ago
    Brand expert
  • A: The directions inside the package say to take 1 pill a day for 3 days and then 2 pills a day thereafter.

    submitted byJaycee - 5 months ago

Q: Are these safe for people with shellfish allergies

submitted by Kooka - 1 year ago
  • A: DS-01® is not formulated with shellfish. Seed conducts comprehensive allergen testing on all of our products, including all 14 classes of allergens defined by the European Food Safety Authority (EFSA). That said, we always encourage a discussion with an allergist or healthcare provider to confirm the appropriateness of our product for those with concerns, sensitivities, or allergies. You can view the full product label with all ingredients here: https://seed.com/reference/syn-wk

    submitted bySeed Team - 2 months ago
    Brand expert

Q: is it possible for men to pop this pill?

submitted by Ktwo - 1 year ago
  • A: What are you talking about a man a blogger turned everybody on to this

    submitted byLinda - 1 year ago
  • A: Thanks so much for reaching out! DS-01® Daily Synbiotic is a 2-in-1 probiotic and prebiotic, formulated for adults ages 18+. The DS-01® formula contains 24 clinically and scientifically studied probiotic strains and a polyphenol-based prebiotic, for benefits in and beyond the gut. The probiotic strains in the DS-01® formula have been backed by 16 strain-specific, published human studies as well as 13 in vitro/ex vivo mechanistic studies to indicate benefits for gastrointestinal function, gut barrier integrity, cardiovascular health, gut immune function, micronutrient synthesis, and dermatological health.

    submitted bySeed Team - 1 year ago
    Brand expert

Q: I see you take 2 capsules a day, but what is the best way to take them? With food? Without food? AM/PM? With water or juice? Thanks!

submitted by AigeP - 2 years ago
  • A: You didn't read the directions it says the first three days take one and after that start taking two to see if your stomach in the a.m. and you don't have to have food on your stomach. You can take it with whatever you want to drink it with

    submitted byLinda - 1 year ago
  • A: Thank you for your question! The daily dosage for DS-01® is 2 capsules per day. We suggest taking the capsules on an empty stomach to limit exposure to digestive enzymes and bile salts, but if it’s more comfortable for you to take DS-01® before/after a meal or alongside food, we encourage you to choose the best method for you. Taking the capsules with water or juice is also absolutely fine. There is no best time of day to take them— we recommend whatever fits best into your routine!

    submitted bySeed Team - 2 years ago
    Brand expert

Q: Is this FSA eligible?

submitted by Snow4Sammy - 19 days ago
  • A: Thank you for reaching out to us! We truly appreciate your interest in our product and understand how important it is to maximize the use of your FSA benefits. At this time, Target does not accept FSA payment methods for our product. On Seed.com we do have a couple of options for FSA users and as an added note, our prices on Seed.com are also lower than Target’s base price.

    submitted bySeed Team - 17 days ago
    Brand expert

Q: Does this product help with mood and handling stress?

submitted by JD - 1 month ago
  • A: DS-01® Daily Synbiotic has not been studied for its effects on stress or mood specifically. Therefore, we're unable to comment on any difference in effect in this regard. For context, DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and supporting the gut barrier. If you’d like to learn more, you can check out our website or reach out directly.

    submitted bySeed Team - 1 month ago
    Brand expert

Q: Does Seed contain Lipase or Amylase?

submitted by Marcia - 2 months ago
  • A: DS-01® Daily Synbiotic is not formulated with amylase or lipase enzymes. It is a 2-in-1 prebiotic and probiotic that combines 24 clinically studied bacterial strains with a non-fiber polyphenol prebiotic compound, punicalagins, sourced from Indian pomegranate. Additional ingredients include vegan capsule materials and organic rice-derived ingredients used to support product stability. You can find our full ingredient list here: https://seed.com/reference/syn-wk#label-101

    submitted bySeed Team - 2 months ago
    Brand expert

Q: How long do I need to take these pills to become effective?

submitted by Jolly Green Giant - 2 months ago
  • A: Every individual’s body is unique, so experiences with DS-01® Daily Synbiotic can vary—there’s no universally consistent timeline for effects felt. Some individuals may notice digestive improvements relatively quickly (within the first week or two), while for others it may take more time as the body uniquely adjusts to the probiotic strains.

    submitted bySeed Team - 2 months ago
    Brand expert

Additional product information and recommendations

Discover more options

Frequently bought together

Guests also viewed

Guests are saying

Guests have found this product to be transformative for their gut health, with many reporting significant improvements in digestion, reduced bloating, and enhanced overall well-being. The unique two-stage capsule technology is praised for its effectiveness in delivering probiotics where they are needed most. While some guests mention the price as a consideration, the positive health benefits and noticeable results make it a worthwhile investment for many. Overall, it has become a staple in their daily routines.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.8 out of 5 stars with 12944 reviews
    67% would recommend
    56 recommendations
    4 out of 5 stars
    14 July, 2026
    originally posted on Seed Health
    Image

    The product itself is fantastic.

    The product itself is fantastic. My complaint is with the packaging for refills. While I understand your desire to minimize packaging, I have had to have at least 3 replacement packages so far due to capsules getting crushed in transit. This seems a great deal of waste in the long run. There has to be a solution that allows for minimal packaging and better protection of the capsules.
    Pam W.
    Did you find this review helpful?
    5 out of 5 stars
    14 July, 2026
    originally posted on Seed Health
    Image

    I've been using the DS-01

    I've been using the DS-01 Daily Synbiotic for years and it has helped tremendously.
    Jen
    Did you find this review helpful?
    3 out of 5 stars
    14 July, 2026
    originally posted on Seed Health
    Image

    After 3 months, It’s just

    After 3 months, It’s just ok. I haven’t noticed an extreme change or anything. So definitely just another probiotic. I will try for another 3 months but not sure it’s worth the cost. I do appreciate the packaging.
    Did you find this review helpful?
    5 out of 5 stars
    14 July, 2026
    originally posted on Seed Health
    Image

    I was curious about trying

    I was curious about trying this probiotic because I am always skeptical of new products on the market. However, after using DS-01 Daily Synbiotic, I have noticed a significant improvement in my digestive system. I used to experience bloating, gas, and discomfort after eating almost everything. It's been nice to feel like I can enjoy my food without worrying about poor digestion. I am very satisfied with the results. Although I can't really afford the price, I have made cuts in my budget so I can continue purchasing my Daily Synbiotic because it has made such a positive difference for me.
    Evelyn C.
    Did you find this review helpful?
    5 out of 5 stars
    14 July, 2026
    originally posted on Seed Health
    Image

    My digestion has become so

    My digestion has become so regular that I have been able to eat some foods I had given up on. I’m not afraid of salads anymore!
    Kathy
    Did you find this review helpful?
    5 out of 5 stars
    13 July, 2026
    originally posted on Seed Health
    Image

    I'm a different person with

    I'm a different person with DS-01 Daily Synbiotic. Couldn't be happier with the product.
    James N.
    Did you find this review helpful?
    5 out of 5 stars
    13 July, 2026
    originally posted on Seed Health
    Image

    Seed has helped my crohns

    Seed has helped my crohns disease symptoms as well as my hair and nail health
    Taylor T.
    Did you find this review helpful?
    5 out of 5 stars
    13 July, 2026
    originally posted on Seed Health
    Image

    I'm really happy with these

    I'm really happy with these and notice a huge difference when I take them. In fact, I ran out of my supply for a couple of weeks and my digestion quickly went downhill without them. Great for bloating and digestion issues. LOVE!
    Skyler N.
    Did you find this review helpful?
    5 out of 5 stars
    13 July, 2026
    originally posted on Seed Health
    Image

    This probiotic has been a

    This probiotic has been a transformative solution for me.
    Dounia
    Did you find this review helpful?
    5 out of 5 stars
    13 July, 2026
    originally posted on Seed Health
    Image

    This product has been extremely

    This product has been extremely helpful during my pregnancy. My midwife recommended it and it’s been incredible.
    Pri
    Did you find this review helpful?
    5 out of 5 stars
    13 July, 2026
    originally posted on Seed Health
    Image

    Goodbye bloating and hello clothing

    Goodbye bloating and hello clothing fitting well and increased energy levels. I feel so much better, have been taking seed for over 2 years!
    Jackie
    Did you find this review helpful?
    5 out of 5 stars
    12 July, 2026
    originally posted on Seed Health
    Image

    This really helped my digestion

    This really helped my digestion speed up and I feel so much better!
    Kendrah
    Did you find this review helpful?
    5 out of 5 stars
    12 July, 2026
    originally posted on Seed Health
    Image

    I have been taking seed

    I have been taking seed symbiotic for about 4 years. It is the best symbiotic that I have ever taken and also got a good report from my recent colonoscopy, than 5 years prior.
    Kathy B.
    Did you find this review helpful?
    5 out of 5 stars
    12 July, 2026
    originally posted on Seed Health
    Image

    This helps so much with

    This helps so much with bloat & keeps my gut feeling good!
    Heather
    Did you find this review helpful?
    5 out of 5 stars
    12 July, 2026
    originally posted on Seed Health
    Image

    This has truly transformed my

    This has truly transformed my gut health, it’s been 2 years using this and I can’t go without it! I’m regular and the bloating has gone all the way down, I’ve never experienced any negative symptoms on it. I’m forever a customer. Thank you Seed
    shali c.
    Did you find this review helpful?
    4 out of 5 stars
    12 July, 2026
    originally posted on Seed Health
    Image

    I noticed more regular BMs

    I noticed more regular BMs initially but now after almost a year it feels like my body has gotten used to the supplement and I could use a stronger dose.
    Lian
    Did you find this review helpful?
    5 out of 5 stars
    12 July, 2026
    originally posted on Seed Health
    Image

    I've been taking this daily

    I've been taking this daily for the past few months and I have noticed less bloating.
    Araceli
    Did you find this review helpful?
    5 out of 5 stars
    12 July, 2026
    originally posted on Seed Health
    Image

    I have the dreaded IBS.

    I have the dreaded IBS. I took DS-01 for a number of months and the protocol improved my gut with less bloating, more regularity and less gas. I stopped my subscription to try other brands that were more affordable but they weren't effective like DS-01. So, I'm going back and just have to pay the price. I recommend for IBS sufferer's.
    Pat
    Did you find this review helpful?
    5 out of 5 stars
    12 July, 2026
    originally posted on Seed Health
    Image

    I was skeptical. Probably because

    I was skeptical. Probably because nothing has ever worked for my stomach. Then I found seed. It took about a month before I started to really notice a difference but phew…. My stomach is doing so much better. Less bloating, less stomach aches, my skin feels softer. This is a health changer for me. 💚
    Tanya
    Did you find this review helpful?
    5 out of 5 stars
    12 July, 2026
    originally posted on Seed Health
    Image

    helped SO much with my

    helped SO much with my bloating, I never bloat now.
    Ashley
    Did you find this review helpful?

    Get top deals, latest trends, and more.