DS-01® Daily Synbiotic is a 24-strain probiotic + prebiotic clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and strengthening the gut barrier.°
60 vegan capsules (30 day supply). Take 2 capsules daily, with or without food. No refrigeration necessary. 53.6 billion AFU.
Proprietary ViaCap® technology safeguards probiotics through digestion to the colon for optimal results.°
24 probiotic strains not found in most foods, yogurts, and beverages, and a polyphenol, non-fiber prebiotic from Indian pomegranate.
DS-01® has been validated in the largest clinical trial for a probiotic on bloating and gas in healthy adults°µ and studied in multiple randomized placebo control trials.
Extensively third-party tested for safety, strength, purity, heavy metals, pesticides, and allergens.
µAs of February 2026. In a randomized placebo-controlled trial on DS-01® Daily Synbiotic, n=350, Allegretti et. al, 2026.
Description
You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. The gut microbiome is connected to various organ systems and pathways throughout the body that are crucial for your health. In a healthy state, the gut microbiome carries out a multitude of functions like regulating digestion, enhancing nutrient absorption, and strengthening immune responses. Seed’s flagship DS-01® Daily Synbiotic is a probiotic and prebiotic developed for whole body health, grounded in science with a deep understanding of the complex interactions within the microbiome. DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and strengthening the gut barrier.°
It contains 24 scientifically studied probiotic strains not commonly found in foods, yogurts, and beverages, and a polyphenolic, non-fiber prebiotic from pomegranate.
Proprietary capsule-in-capsule technology is intentionally engineered to safeguard probiotics through digestion, promoting survivability from stomach acid, digestive enzymes, moisture, and heat.*
Extensively third-party tested for safety, strength, purity, heavy metals, pesticides, and allergens.
Each jar contains 60 capsules, providing a 30-day supply of 53.6 billion AFU per dose with no refrigeration required.
*Based on a study conducted in SHIME®. Results may vary. °These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Contains: Does Not Contain Any of the 9 Major Allergens
Suggested Age: 18 Years and Up
Product Warning: Consult a doctor if you are pregnant or nursing, keep out of reach of children
Product Form: Capsule
Package Quantity: 60
Colony forming units (billions): 0
Active fluorescent units (billions): 53.6
TCIN: 91816039
UPC: 860340001620
Item Number (DPCI): 094-02-5724
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.
If you are attempting to become, or are pregnant or nursing, consult your healthcare provider before use. Keep out of reach of children. Do not use if seal is broken.
Shipping details
Estimated ship dimensions: 2.87 inches length x 2.91 inches width x 3.45 inches height
Estimated ship weight: 0.54 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
A: What are you talking about a man a blogger turned everybody on to this
submitted byLinda - 1 year ago
A: Thanks so much for reaching out! DS-01® Daily Synbiotic is a 2-in-1 probiotic and prebiotic, formulated for adults ages 18+. The DS-01® formula contains 24 clinically and scientifically studied probiotic strains and a polyphenol-based prebiotic, for benefits in and beyond the gut.
The probiotic strains in the DS-01® formula have been backed by 16 strain-specific, published human studies as well as 13 in vitro/ex vivo mechanistic studies to indicate benefits for gastrointestinal function, gut barrier integrity, cardiovascular health, gut immune function, micronutrient synthesis, and dermatological health.
submitted bySeed Team - 2 years ago
Brand expert
Q: I have diverticulosis would this help?
submitted by Yvette - 2 years ago
A: DS-01® Daily Synbiotic isn’t intended to treat, diagnose, prevent or cure any condition or disease, including diverticulosis. Therefore, we’re unable to comment on its safety, suitability, or efficacy in this specific context. For those with pre-existing conditions, we always suggest an informed conversation with a healthcare provider who may advise on the addition of DS-01® given your health history.
For context, DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and supporting the gut barrier. If you’d like to learn more, you can check out our website or reach out directly.
submitted bySeed Team - 3 months ago
Brand expert
Q: Hard to swallow? I have problems with large caps and these look large.
submitted by Nansky - 2 years ago
A: Yes this is a big concern for me too hope you will show size of pill.
submitted bystoragelessshopper - 1 year ago
A: I only swallow with food and these are not bad. Pretty standard size.
submitted byFmz - 2 years ago
A: Thanks so much for your question! Our DS-01® Daily Synbiotic capsule is size 00—that’s 0.917 inches long with a diameter of 0.322 inches, to be exact. We wouldn't recommend opening or tampering with the DS-01® Daily Synbiotic capsules in any way, as our ViaCap® is especially designed to ensure the bacteria stay alive through digestion and make it to the colon. That said, you may certainly try experimenting with how you may be able to tolerate the capsules—any method in which you can preserve the 2-in-1 ViaCap® capsule would be perfectly fine. Please reach out to care@seed.com with any additional questions!
submitted bySeed Team - 2 years ago
Brand expert
Q: How many pills per day are recommended?
submitted by Judy - 7 months ago
A: The daily dosage for DS-01® is two capsules per day (which includes 53.6B AFU + 400mg Indian Pomegranate). DS-01® can be taken any time of day—consistent daily intake is most important. We generally recommend taking the capsules together, but feel free to space it out if that works better for your routine.
submitted bySeed Team - 7 months ago
Brand expert
A: The directions inside the package say to take 1 pill a day for 3 days and then 2 pills a day thereafter.
submitted byJaycee - 7 months ago
Q: Are these safe for people with shellfish allergies
submitted by Kooka - 1 year ago
A: DS-01® is not formulated with shellfish. Seed conducts comprehensive allergen testing on all of our products, including all 14 classes of allergens defined by the European Food Safety Authority (EFSA). That said, we always encourage a discussion with an allergist or healthcare provider to confirm the appropriateness of our product for those with concerns, sensitivities, or allergies. You can view the full product label with all ingredients here: https://seed.com/reference/syn-wk
submitted bySeed Team - 3 months ago
Brand expert
Q: I see you take 2 capsules a day, but what is the best way to take them? With food? Without food? AM/PM? With water or juice? Thanks!
submitted by AigeP - 2 years ago
A: You didn't read the directions it says the first three days take one and after that start taking two to see if your stomach in the a.m. and you don't have to have food on your stomach. You can take it with whatever you want to drink it with
submitted byLinda - 1 year ago
A: Thank you for your question! The daily dosage for DS-01® is 2 capsules per day. We suggest taking the capsules on an empty stomach to limit exposure to digestive enzymes and bile salts, but if it’s more comfortable for you to take DS-01® before/after a meal or alongside food, we encourage you to choose the best method for you. Taking the capsules with water or juice is also absolutely fine. There is no best time of day to take them— we recommend whatever fits best into your routine!
submitted bySeed Team - 2 years ago
Brand expert
Q: Does Seed cause gas and bloating as your system gets used to it?
submitted by SS - 17 days ago
A: When starting a new probiotic like DS-01®, some people notice mild digestive changes as the gut adjusts. This can include gas, bloating, GI discomfort, or changes to stool, which are generally mild and temporary—often subsiding with the first few weeks or so of consistent use.
Because each microbiome is distinct, each experience is as well. In fact, while some individuals may experience an adjustment, many others do not.
If you’re prone to digestive sensitivity or have any concerns, we’d encourage a discussion with your healthcare provider before introduction, so they can advise within the context of your health history.
submitted bySeed Team - 16 days ago
Brand expert
Q: What can I take along with this to help my constipation
submitted by nelle - 1 month ago
A: Probiotics are considered safe to take alongside most medications, but we always recommend checking with your prescribing provider before adding a new product to your routine.
submitted bySeed Team - 1 month ago
Brand expert
Q: I was taking lanural but stopped. I am starting seed to see if it works. Willthere be any effects
submitted by nelle - 1 month ago
A: When starting a new probiotic like DS-01®, some people notice mild digestive changes as the gut adjusts. This can include gas, bloating, GI discomfort, or changes to stool, which are generally mild and temporary—often subsiding with the first few weeks or so of consistent use.
Because each microbiome is distinct, each experience is as well. In fact, while some individuals may experience an adjustment, many others do not.
If you’re prone to digestive sensitivity or have any concerns, we’d encourage a discussion with your healthcare provider before introduction, so they can advise within the context of your health history.
submitted bySeed Team - 1 month ago
Brand expert
Q: What types of medicine should not be taken with these.?
submitted by Kbd - 1 month ago
A: Great question! Probiotics are considered safe to take alongside most medications, but we always recommend checking with your prescribing provider before adding a new product to your routine.
Guests have reported significant improvements in their digestive health after using this product for varying durations. Many have experienced reduced bloating, increased regularity, and overall better gut health. The product is praised for its ease of use and effectiveness, with some guests noting improvements in skin clarity and energy levels. While some guests have concerns about the price, the majority feel that the benefits outweigh the costs, making it a worthwhile addition to their daily routine.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.8
4.8 out of 5 stars
13450 star ratings
4.8 out of 5 stars with 13450 reviews
67% would recommend
56 recommendations
5 out of 5 stars
31 August, 2026
originally posted on Seed Health
Absolutely love how I feel
Absolutely love how I feel and can see a difference now that I’ve been using it consistently for the past 6 months
Taylor
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5 out of 5 stars
31 August, 2026
originally posted on Seed Health
I first heard about Seed
I first heard about Seed through an influencer named Thomas Lauer. The gentleman is filled with extensive knowledge so I decided to try it out for myself and I’m glad I did. I always had issues with bloating and gas and digestion not understanding the importance of gut micro, biome in a diversity. So with that in mind, I decided to try it after a few weeks. I noticed digestion was easier I’d wake up in the morning with a flat stomach in my overall mental state felt clear. It was a total game changer for me. I’ve recommended to many of my friends, and they have the same thing to say.
John D.
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5 out of 5 stars
31 August, 2026
originally posted on Seed Health
You really start feeling the
You really start feeling the product working once you start taking it! It’s amazing.
Mary
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4 out of 5 stars
31 August, 2026
originally posted on Seed Health
I give it a 4
I give it a 4 star because I’ve never been consistent on any other probiotic to make a comparison. I followed the directions and take 2 daily. I noticed an immediate improvement in my BM regularity. I’m hoping this means my gut health is better, only time will tell. I didnt notice a big difference between taking 1/day or 2/day. I may go back to 1/day.
Richelle
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5 out of 5 stars
31 August, 2026
originally posted on Seed Health
I’ve battled with being stopped
I’ve battled with being stopped up my entire life. When I take these diligently every night before bed, I totally regular. I’ve never felt better.
Erin
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5 out of 5 stars
31 August, 2026
originally posted on Seed Health
I’ve taken this daily for
I’ve taken this daily for a few months now and I’ve experienced a nice adjustment in my overall gut health. Online experience is superb and it’s really easy to adjust my refills dates when needed. Overall would recommend just as it was recommended to me.
Rico M.
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4 out of 5 stars
31 August, 2026
originally posted on Seed Health
Still feeling it out. I’ve
Still feeling it out. I’ve taken it for three months and I’m going to keep staying the course for a few more. I want to see more improvement in order to justify the cost. I have IBS and my anxiety impacts my gut a lot. Have no other known conditions but was hoping this would help with episodes of tummy troubles I believe are linked to anxiety induced ibs. So far I don’t see a super noticeable improvement.
Pamela
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5 out of 5 stars
30 August, 2026
originally posted on Seed Health
this synbiotic is a GAME
this synbiotic is a GAME CHANGER!!!! I’ve tried so many probiotics and none of them have worked or made me feel any better until Seed.
Sarah
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5 out of 5 stars
30 August, 2026
originally posted on Seed Health
This is the best probiotic
This is the best probiotic I’ve ever taken. It has helped keep my gut healthy and I haven’t seen a relapse with my GI autoimmune disease since taking it. My son’s digestive issues have gone away since he started taking it too!
CK
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5 out of 5 stars
30 August, 2026
originally posted on Seed Health
Gut digestion has gotten so
Gut digestion has gotten so much better! Less upset in the afternoon/evening when I normally would have stomach issues!
Destiny
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5 out of 5 stars
30 August, 2026
originally posted on Seed Health
I definitely feel better taking
I definitely feel better taking this product, more than any other one I have tried.
Anna G.
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5 out of 5 stars
30 August, 2026
originally posted on Seed Health
I’m regulated like never before.
I’m regulated like never before. Thanks to seed I have achieved, what I think and feel, as a healthy balanced life.
Dylan M.
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5 out of 5 stars
30 August, 2026
originally posted on Seed Health
I have been using DS-01
I have been using DS-01 Daily Synbiotic for over a year and amazed how well it works with a sensitive stomach and digestive issues.
Pamela C.
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5 out of 5 stars
30 August, 2026
originally posted on Seed Health
This product has made a
This product has made a huge difference in my gut health. I’ve noticed that I feel better and my skin looks healthier also.
Terri
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5 out of 5 stars
30 August, 2026
originally posted on Seed Health
Very happy with the results
Very happy with the results so far and saw improvement in my digestive system within the 1st 2 weeks of using.
Jessica
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4 out of 5 stars
30 August, 2026
originally posted on Seed Health
Thought it wasn’t working until
Thought it wasn’t working until I stopped and realized it truly was !! Starting again !!
April H.
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5 out of 5 stars
30 August, 2026
originally posted on Seed Health
I have takings DS-01 for
I have takings DS-01 for about 4 weeks and I can see that my bowels are making small improvements more than any other product I’ve tried. I recommend trying it.
Kimberly B.
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5 out of 5 stars
28 August, 2026
originally posted on Seed Health
This stuff is amazing. Started
This stuff is amazing. Started it while on GLP 1 meds to offset some of the gastrointestinal side effects. What I didn’t expect is that around the third month my skin and hair felt and looked so healthy. You’ll literally feel the difference in both! Love this stuff
Shannon S.
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5 out of 5 stars
28 August, 2026
originally posted on Seed Health
Completely changed my gut for
Completely changed my gut for the better. Finally felt like I wasn't bloated all the time after trying so many different probiotics.
Sofia
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5 out of 5 stars
28 August, 2026
originally posted on Seed Health
I have such bad gut
I have such bad gut health including constipation for many years. Since taking seed I have seen some improvement overall. Most importantly I've been on a lot of antibiotics lately and seed helps build up my microbiome.