DS-01® Daily Synbiotic is a 24-strain probiotic + prebiotic clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and strengthening the gut barrier.°
60 vegan capsules (30 day supply). Take 2 capsules daily, with or without food. No refrigeration necessary. 53.6 billion AFU.
Proprietary ViaCap® technology safeguards probiotics through digestion to the colon for optimal results.°
24 probiotic strains not found in most foods, yogurts, and beverages, and a polyphenol, non-fiber prebiotic from Indian pomegranate.
DS-01® has been validated in the largest clinical trial for a probiotic on bloating and gas in healthy adults°µ and studied in multiple randomized placebo control trials.
Extensively third-party tested for safety, strength, purity, heavy metals, pesticides, and allergens.
µAs of February 2026. In a randomized placebo-controlled trial on DS-01® Daily Synbiotic, n=350, Allegretti et. al, 2026.
Description
You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. The gut microbiome is connected to various organ systems and pathways throughout the body that are crucial for your health. In a healthy state, the gut microbiome carries out a multitude of functions like regulating digestion, enhancing nutrient absorption, and strengthening immune responses. Seed’s flagship DS-01® Daily Synbiotic is a probiotic and prebiotic developed for whole body health, grounded in science with a deep understanding of the complex interactions within the microbiome. DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and strengthening the gut barrier.°
It contains 24 scientifically studied probiotic strains not commonly found in foods, yogurts, and beverages, and a polyphenolic, non-fiber prebiotic from pomegranate.
Proprietary capsule-in-capsule technology is intentionally engineered to safeguard probiotics through digestion, promoting survivability from stomach acid, digestive enzymes, moisture, and heat.*
Extensively third-party tested for safety, strength, purity, heavy metals, pesticides, and allergens.
Each jar contains 60 capsules, providing a 30-day supply of 53.6 billion AFU per dose with no refrigeration required.
*Based on a study conducted in SHIME®. Results may vary. °These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Contains: Does Not Contain Any of the 9 Major Allergens
Suggested Age: 18 Years and Up
Product Warning: Consult a doctor if you are pregnant or nursing, keep out of reach of children
Product Form: Capsule
Package Quantity: 60
Colony forming units (billions): 0
Active fluorescent units (billions): 53.6
TCIN: 91816039
UPC: 860340001620
Item Number (DPCI): 094-02-5724
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.
If you are attempting to become, or are pregnant or nursing, consult your healthcare provider before use. Keep out of reach of children. Do not use if seal is broken.
Shipping details
Estimated ship dimensions: 2.87 inches length x 2.91 inches width x 3.45 inches height
Estimated ship weight: 0.54 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
A: What are you talking about a man a blogger turned everybody on to this
submitted byLinda - 1 year ago
A: Thanks so much for reaching out! DS-01® Daily Synbiotic is a 2-in-1 probiotic and prebiotic, formulated for adults ages 18+. The DS-01® formula contains 24 clinically and scientifically studied probiotic strains and a polyphenol-based prebiotic, for benefits in and beyond the gut.
The probiotic strains in the DS-01® formula have been backed by 16 strain-specific, published human studies as well as 13 in vitro/ex vivo mechanistic studies to indicate benefits for gastrointestinal function, gut barrier integrity, cardiovascular health, gut immune function, micronutrient synthesis, and dermatological health.
submitted bySeed Team - 2 years ago
Brand expert
Q: I have diverticulosis would this help?
submitted by Yvette - 2 years ago
A: DS-01® Daily Synbiotic isn’t intended to treat, diagnose, prevent or cure any condition or disease, including diverticulosis. Therefore, we’re unable to comment on its safety, suitability, or efficacy in this specific context. For those with pre-existing conditions, we always suggest an informed conversation with a healthcare provider who may advise on the addition of DS-01® given your health history.
For context, DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and supporting the gut barrier. If you’d like to learn more, you can check out our website or reach out directly.
submitted bySeed Team - 3 months ago
Brand expert
Q: Hard to swallow? I have problems with large caps and these look large.
submitted by Nansky - 2 years ago
A: Yes this is a big concern for me too hope you will show size of pill.
submitted bystoragelessshopper - 1 year ago
A: I only swallow with food and these are not bad. Pretty standard size.
submitted byFmz - 2 years ago
A: Thanks so much for your question! Our DS-01® Daily Synbiotic capsule is size 00—that’s 0.917 inches long with a diameter of 0.322 inches, to be exact. We wouldn't recommend opening or tampering with the DS-01® Daily Synbiotic capsules in any way, as our ViaCap® is especially designed to ensure the bacteria stay alive through digestion and make it to the colon. That said, you may certainly try experimenting with how you may be able to tolerate the capsules—any method in which you can preserve the 2-in-1 ViaCap® capsule would be perfectly fine. Please reach out to care@seed.com with any additional questions!
submitted bySeed Team - 2 years ago
Brand expert
Q: How many pills per day are recommended?
submitted by Judy - 7 months ago
A: The daily dosage for DS-01® is two capsules per day (which includes 53.6B AFU + 400mg Indian Pomegranate). DS-01® can be taken any time of day—consistent daily intake is most important. We generally recommend taking the capsules together, but feel free to space it out if that works better for your routine.
submitted bySeed Team - 7 months ago
Brand expert
A: The directions inside the package say to take 1 pill a day for 3 days and then 2 pills a day thereafter.
submitted byJaycee - 7 months ago
Q: Are these safe for people with shellfish allergies
submitted by Kooka - 1 year ago
A: DS-01® is not formulated with shellfish. Seed conducts comprehensive allergen testing on all of our products, including all 14 classes of allergens defined by the European Food Safety Authority (EFSA). That said, we always encourage a discussion with an allergist or healthcare provider to confirm the appropriateness of our product for those with concerns, sensitivities, or allergies. You can view the full product label with all ingredients here: https://seed.com/reference/syn-wk
submitted bySeed Team - 3 months ago
Brand expert
Q: I see you take 2 capsules a day, but what is the best way to take them? With food? Without food? AM/PM? With water or juice? Thanks!
submitted by AigeP - 2 years ago
A: You didn't read the directions it says the first three days take one and after that start taking two to see if your stomach in the a.m. and you don't have to have food on your stomach. You can take it with whatever you want to drink it with
submitted byLinda - 1 year ago
A: Thank you for your question! The daily dosage for DS-01® is 2 capsules per day. We suggest taking the capsules on an empty stomach to limit exposure to digestive enzymes and bile salts, but if it’s more comfortable for you to take DS-01® before/after a meal or alongside food, we encourage you to choose the best method for you. Taking the capsules with water or juice is also absolutely fine. There is no best time of day to take them— we recommend whatever fits best into your routine!
submitted bySeed Team - 2 years ago
Brand expert
Q: Does Seed cause gas and bloating as your system gets used to it?
submitted by SS - 21 days ago
A: When starting a new probiotic like DS-01®, some people notice mild digestive changes as the gut adjusts. This can include gas, bloating, GI discomfort, or changes to stool, which are generally mild and temporary—often subsiding with the first few weeks or so of consistent use.
Because each microbiome is distinct, each experience is as well. In fact, while some individuals may experience an adjustment, many others do not.
If you’re prone to digestive sensitivity or have any concerns, we’d encourage a discussion with your healthcare provider before introduction, so they can advise within the context of your health history.
submitted bySeed Team - 20 days ago
Brand expert
Q: What can I take along with this to help my constipation
submitted by nelle - 2 months ago
A: Probiotics are considered safe to take alongside most medications, but we always recommend checking with your prescribing provider before adding a new product to your routine.
submitted bySeed Team - 1 month ago
Brand expert
Q: I was taking lanural but stopped. I am starting seed to see if it works. Willthere be any effects
submitted by nelle - 2 months ago
A: When starting a new probiotic like DS-01®, some people notice mild digestive changes as the gut adjusts. This can include gas, bloating, GI discomfort, or changes to stool, which are generally mild and temporary—often subsiding with the first few weeks or so of consistent use.
Because each microbiome is distinct, each experience is as well. In fact, while some individuals may experience an adjustment, many others do not.
If you’re prone to digestive sensitivity or have any concerns, we’d encourage a discussion with your healthcare provider before introduction, so they can advise within the context of your health history.
submitted bySeed Team - 1 month ago
Brand expert
Q: What types of medicine should not be taken with these.?
submitted by Kbd - 2 months ago
A: Great question! Probiotics are considered safe to take alongside most medications, but we always recommend checking with your prescribing provider before adding a new product to your routine.
Guests have reported significant improvements in their digestive health after using this product for varying durations. Many have experienced reduced bloating, increased regularity, and overall better gut health. The product is praised for its ease of use and effectiveness, with some guests noting improvements in skin clarity and energy levels. While some guests have concerns about the price, the majority feel that the benefits outweigh the costs, making it a worthwhile addition to their daily routine.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.8
4.8 out of 5 stars
13485 star ratings
4.8 out of 5 stars with 13485 reviews
67% would recommend
56 recommendations
5 out of 5 stars
4 September, 2026
originally posted on Seed Health
On a GLP-1, this is
On a GLP-1, this is a MUST! No Constipation! No tummy aches! Second you wake up, take 2 and go on with the day! I can not imagine anyone not wanting to take this!
Dan
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5 out of 5 stars
4 September, 2026
originally posted on Seed Health
Seed changed my daily life.
Seed changed my daily life. I started taking it nearly 2 years ago and my body feels so much better. I’ve recommended it to all my friends and family!
Rebecca
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5 out of 5 stars
4 September, 2026
originally posted on Seed Health
My doctor recomended this to
My doctor recomended this to help with my painful gas and bloating, this actually has helped me a lot, I feel like most of my symptoms have gotten way way better.
Roniit
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5 out of 5 stars
4 September, 2026
originally posted on Seed Health
Seed has positively impacted my
Seed has positively impacted my gut health. I started taking it because I was frequently feeling gassy and this has really helped alleviate it.
Karen
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5 out of 5 stars
4 September, 2026
originally posted on Seed Health
I bought this for my
I bought this for my significant other, who has had ongoing bowel issues for years. After almost every meal, he'd need to rush to the bathroom, and his stools were rarely well-formed. Since taking Seed, he's reported a noticeable improvement in both consistency and overall digestion. We're impressed with the results so far and will be continuing with a monthly purchase
Jackie E.
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4 out of 5 stars
4 September, 2026
originally posted on Seed Health
Has really helped the noises
Has really helped the noises from my stomach. Makes everything more regular on a daily basis
Nancy
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5 out of 5 stars
4 September, 2026
originally posted on Seed Health
This is the best probiotic
This is the best probiotic I’ve ever tried. It is a bit pricey but worth it. I initially tried Seed after seeing an ad and liked the fact that the probiotic actually reaches the colon and doesn’t get eaten up by stomach acid before it has a chance to do anything. My bowel movements are very regular and I don’t have the bloating that I usually would have during my period. Try it. It may work for you!
Tye L.
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5 out of 5 stars
3 September, 2026
originally posted on Seed Health
Love love love, these made
Love love love, these made a world of difference. It’s hard to explain other than I just FEEL better since starting them.
Tabatha
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5 out of 5 stars
3 September, 2026
originally posted on Seed Health
I have been taking DS-01
I have been taking DS-01 for a short couple of week and already have an overall better feeling in my gut.
Robert H.
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5 out of 5 stars
3 September, 2026
originally posted on Seed Health
I’ve struggled with digestion issue
I’ve struggled with digestion issue for years. Started with elimination diets and just could not get to the bottom of what was causing my issues. Tried so many different pre, pro, and symbiotics but nothing seemed to help. Finally tried the DS-01 and I’ve felt so much better since! I’m having less bloating, gas, and nausea after every meal. I also feel like I can eat what I want without fear of being uncomfortable after. It’s also so easy to add to the day that I now can imagine not having it!
Carley
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5 out of 5 stars
3 September, 2026
originally posted on Seed Health
Since taking daily synbiotic, I've
Since taking daily synbiotic, I've been more regular than ever. This is my holy grail supplement.
Olivia
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5 out of 5 stars
2 September, 2026
originally posted on Seed Health
Amazing probiotic! Been taking it
Amazing probiotic! Been taking it for 7 years and can’t stop raving about it. I highly recommend to everyone.
Brenda C.
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5 out of 5 stars
2 September, 2026
originally posted on Seed Health
Incredible
This product delivers on its promises. Very grateful to have come across advertisements regarding the property of Seed DS-01. DS-01 has become a permanent element in my daily routine.
Monica P.
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5 out of 5 stars
2 September, 2026
originally posted on Seed Health
It really has helped me
It really has helped me feel better and less bloated while also keeping me regular. Love this stuff.
Robin W.
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5 out of 5 stars
2 September, 2026
originally posted on Seed Health
Excellent
I’ve taken probiotics all my adult life and this is first one that actually stops swelling and belly and intestinal pain.
Amy C.
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5 out of 5 stars
2 September, 2026
originally posted on Seed Health
i’ve been using now for
i’ve been using now for about 6 months. bloating is significantly better, and an added side benefits i wasn’t expecting is how good my skin looks
Danielle
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4 out of 5 stars
2 September, 2026
originally posted on Seed Health
Works well if consistent. Managed
Works well if consistent. Managed my IBS symptoms including bloating and constipation. But very pricey to be taking every day.
Peggy
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5 out of 5 stars
2 September, 2026
originally posted on Seed Health
DS-01 is amazing! I had
DS-01 is amazing! I had my gallbladder removed and have had issues with digestion. My bloat is gone now!
Kelsey M.
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5 out of 5 stars
2 September, 2026
originally posted on Seed Health
Seed has helped me with
Seed has helped me with my digestion and would recommend it
Stacy
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5 out of 5 stars
1 September, 2026
originally posted on Seed Health
High quality product that does
High quality product that does what it says it will in a highly safe way. Gently brings normalcy back to your digestive function.