Target New ArrivalsHalloweenChristmasGift IdeasClothing, Shoes & AccessoriesHome & DecorKitchen & DiningPatio, Lawn & GardenGroceryHousehold EssentialsBabyBeautyTarget Beauty StudioPersonal CareSports & OutdoorsPetsHealthWellnessSchool & Office SuppliesToys & GamesElectronics & TechVideo GamesBooks, Music & MoviesParty SuppliesGift CardsShop by CommunityTarget OpticalDealsClearanceNew ArrivalsBack to SchoolCollegeTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Seed Daily Synbiotic Probiotic Capsules - 60ct - 2 of 4Seed Daily Synbiotic Probiotic Capsules - 60ct - 3 of 4Seed Daily Synbiotic Probiotic Capsules - 60ct - 4 of 4
Seed Daily Synbiotic Probiotic Capsules - 60ct - 1 of 4

Seed Daily Synbiotic Probiotic Capsules - 60ct

44 Questions
$59.99
 

In Stock

Eligible for registries and wish lists
Save 5% every day
With Target Circle™ Card (restrictions apply)

At a glance

About this item

Highlights

  • DS-01® Daily Synbiotic is a 24-strain probiotic + prebiotic clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and strengthening the gut barrier.°
  • 60 vegan capsules (30 day supply). Take 2 capsules daily, with or without food. No refrigeration necessary. 53.6 billion AFU.
  • Proprietary ViaCap® technology safeguards probiotics through digestion to the colon for optimal results.°
  • 24 probiotic strains not found in most foods, yogurts, and beverages, and a polyphenol, non-fiber prebiotic from Indian pomegranate.
  • DS-01® has been validated in the largest clinical trial for a probiotic on bloating and gas in healthy adults°µ and studied in multiple randomized placebo control trials.
  • Extensively third-party tested for safety, strength, purity, heavy metals, pesticides, and allergens.
  • µAs of February 2026. In a randomized placebo-controlled trial on DS-01® Daily Synbiotic, n=350, Allegretti et. al, 2026.

Description

You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. The gut microbiome is connected to various organ systems and pathways throughout the body that are crucial for your health. In a healthy state, the gut microbiome carries out a multitude of functions like regulating digestion, enhancing nutrient absorption, and strengthening immune responses.

Seed’s flagship DS-01® Daily Synbiotic is a probiotic and prebiotic developed for whole body health, grounded in science with a deep understanding of the complex interactions within the microbiome. DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and strengthening the gut barrier.°

It contains 24 scientifically studied probiotic strains not commonly found in foods, yogurts, and beverages, and a polyphenolic, non-fiber prebiotic from pomegranate.

Proprietary capsule-in-capsule technology is intentionally engineered to safeguard probiotics through digestion, promoting survivability from stomach acid, digestive enzymes, moisture, and heat.*

Extensively third-party tested for safety, strength, purity, heavy metals, pesticides, and allergens.

Each jar contains 60 capsules, providing a 30-day supply of 53.6 billion AFU per dose with no refrigeration required.

*Based on a study conducted in SHIME®. Results may vary.
°These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Contains: Does Not Contain Any of the 9 Major Allergens
Suggested Age: 18 Years and Up
Product Warning: Consult a doctor if you are pregnant or nursing, keep out of reach of children
Product Form: Capsule
Package Quantity: 60
Colony forming units (billions): 0
Active fluorescent units (billions): 53.6
TCIN: 91816039
UPC: 860340001620
Item Number (DPCI): 094-02-5724
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Amount Amount Per Serving

% Daily Value*
Digestive Health Probiotic Blend 206mg
Micronutrient Synthesis Probiotic Blend 46mg
Dermatological Health Probiotic Blend 37mg
Cardiovascular Health Probiotic Blend 18mg
MAPP Microbiota-Accessible Polyphenolic Precursors 400mg
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

acid-resistant vegan outer [chlorophyllin] and inner [hypromellose, water] capsules, organic rice fiber, organic rice extract blend.

Allergens & Warnings:

If you are attempting to become, or are pregnant or nursing, consult your healthcare provider before use. Keep out of reach of children. Do not use if seal is broken.

Shipping details

Estimated ship dimensions: 2.87 inches length x 2.91 inches width x 3.45 inches height
Estimated ship weight: 0.54 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: is it possible for men to pop this pill?

submitted by Ktwo - 2 years ago
  • A: What are you talking about a man a blogger turned everybody on to this

    submitted byLinda - 2 years ago
  • A: Thanks so much for reaching out! DS-01® Daily Synbiotic is a 2-in-1 probiotic and prebiotic, formulated for adults ages 18+. The DS-01® formula contains 24 clinically and scientifically studied probiotic strains and a polyphenol-based prebiotic, for benefits in and beyond the gut. The probiotic strains in the DS-01® formula have been backed by 16 strain-specific, published human studies as well as 13 in vitro/ex vivo mechanistic studies to indicate benefits for gastrointestinal function, gut barrier integrity, cardiovascular health, gut immune function, micronutrient synthesis, and dermatological health.

    submitted bySeed Team - 2 years ago
    Brand expert

Q: I have diverticulosis would this help?

submitted by Yvette - 2 years ago
  • A: DS-01® Daily Synbiotic isn’t intended to treat, diagnose, prevent or cure any condition or disease, including diverticulosis. Therefore, we’re unable to comment on its safety, suitability, or efficacy in this specific context. For those with pre-existing conditions, we always suggest an informed conversation with a healthcare provider who may advise on the addition of DS-01® given your health history. For context, DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and supporting the gut barrier. If you’d like to learn more, you can check out our website or reach out directly.

    submitted bySeed Team - 4 months ago
    Brand expert

Q: Hard to swallow? I have problems with large caps and these look large.

submitted by Nansky - 2 years ago
  • A: Yes this is a big concern for me too hope you will show size of pill.

    submitted bystoragelessshopper - 1 year ago
  • A: I only swallow with food and these are not bad. Pretty standard size.

    submitted byFmz - 2 years ago
  • A: Thanks so much for your question! Our DS-01® Daily Synbiotic capsule is size 00—that’s 0.917 inches long with a diameter of 0.322 inches, to be exact. We wouldn't recommend opening or tampering with the DS-01® Daily Synbiotic capsules in any way, as our ViaCap® is especially designed to ensure the bacteria stay alive through digestion and make it to the colon. That said, you may certainly try experimenting with how you may be able to tolerate the capsules—any method in which you can preserve the 2-in-1 ViaCap® capsule would be perfectly fine. Please reach out to care@seed.com with any additional questions!

    submitted bySeed Team - 2 years ago
    Brand expert

Q: How many pills per day are recommended?

submitted by Judy - 8 months ago
  • A: The daily dosage for DS-01® is two capsules per day (which includes 53.6B AFU + 400mg Indian Pomegranate). DS-01® can be taken any time of day—consistent daily intake is most important. We generally recommend taking the capsules together, but feel free to space it out if that works better for your routine.

    submitted bySeed Team - 8 months ago
    Brand expert
  • A: The directions inside the package say to take 1 pill a day for 3 days and then 2 pills a day thereafter.

    submitted byJaycee - 8 months ago

Q: Are these safe for people with shellfish allergies

submitted by Kooka - 2 years ago
  • A: DS-01® is not formulated with shellfish. Seed conducts comprehensive allergen testing on all of our products, including all 14 classes of allergens defined by the European Food Safety Authority (EFSA). That said, we always encourage a discussion with an allergist or healthcare provider to confirm the appropriateness of our product for those with concerns, sensitivities, or allergies. You can view the full product label with all ingredients here: https://seed.com/reference/syn-wk

    submitted bySeed Team - 4 months ago
    Brand expert

Q: I see you take 2 capsules a day, but what is the best way to take them? With food? Without food? AM/PM? With water or juice? Thanks!

submitted by AigeP - 2 years ago
  • A: You didn't read the directions it says the first three days take one and after that start taking two to see if your stomach in the a.m. and you don't have to have food on your stomach. You can take it with whatever you want to drink it with

    submitted byLinda - 2 years ago
  • A: Thank you for your question! The daily dosage for DS-01® is 2 capsules per day. We suggest taking the capsules on an empty stomach to limit exposure to digestive enzymes and bile salts, but if it’s more comfortable for you to take DS-01® before/after a meal or alongside food, we encourage you to choose the best method for you. Taking the capsules with water or juice is also absolutely fine. There is no best time of day to take them— we recommend whatever fits best into your routine!

    submitted bySeed Team - 2 years ago
    Brand expert

Q: Is this eligible for OTC benefit ?

submitted by Ow - 22 days ago
  • A: Great question! We don’t currently accept FSA/HSA cards directly for that product. However, we partner with TrueMed to support reimbursement. Here’s how it works: 1. Complete TrueMed’s quick evaluation [https://app.truemed.com/qualify/tm_qual_juyb1w4lmo] ($12 fee, FSA/HSA eligible). 2. If eligible, TrueMed will email you a Letter of Medical Necessity. 3. Submit your LMN and Seed receipt(s) to your FSA/HSA provider for reimbursement. Receipts can be downloaded anytime in your Seed Account under Order History. Please don't hesitate to send our Care team an email at care@seed.com with any other questions, and we'll be happy to help!

    submitted bySeed Team - 21 days ago
    Brand expert

Q: What strains of probiotics does this contain and how much of each?

submitted by Manteca Man - 1 month ago
  • A: Great questions! You can find our complete strain list and included ingredients here: https://seed.com/reference/syn-wk#label-101

    submitted bySeed Team - 1 month ago
    Brand expert

Q: What are the ingredients?

submitted by Lijon - 1 month ago
  • A: Thanks for reaching out! DS-01® is a 2-in-1 prebiotic and probiotic that combines 24 select bacterial strains and a non-fiber polyphenol prebiotic compound: punicalagins, which is sourced from Indian Pomegranate. You can find our complete strain list and included ingredients here: https://seed.com/reference/syn-wk#label-101

    submitted bySeed Team - 1 month ago
    Brand expert

Q: Does Seed cause gas and bloating as your system gets used to it?

submitted by SS - 2 months ago
  • A: When starting a new probiotic like DS-01®, some people notice mild digestive changes as the gut adjusts. This can include gas, bloating, GI discomfort, or changes to stool, which are generally mild and temporary—often subsiding with the first few weeks or so of consistent use. Because each microbiome is distinct, each experience is as well. In fact, while some individuals may experience an adjustment, many others do not. If you’re prone to digestive sensitivity or have any concerns, we’d encourage a discussion with your healthcare provider before introduction, so they can advise within the context of your health history.

    submitted bySeed Team - 2 months ago
    Brand expert

Additional product information and recommendations

Discover more options

Skip to next section

Frequently bought together

Skip to next section

Guests also viewed

Skip to next section

Guests are saying

Guests have found this probiotic to be a transformative addition to their daily routines, significantly improving gut health, regularity, and overall well-being. Many have reported noticeable reductions in bloating and digestive discomfort, with some experiencing enhanced energy levels and clearer skin. The product is praised for its easy-to-take capsules and premium packaging, making it a convenient choice for those seeking reliable digestive support. Overall, it has earned a loyal following among guests who appreciate its effectiveness and quality.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.8 out of 5 stars with 14347 reviews
    66% would recommend
    60 recommendations
    5 out of 5 stars
    6 October, 2026
    originally posted on Seed Health
    Image

    I started taking DS-01 a

    I started taking DS-01 a couple year ago an my gut and wellness has never felt better. My bowl movements are consistent and it helps me empty all digested food at once. It is such a relief. My thoughts are clear and I don't get tired after meals. Keep it coming!
    Greg W.
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    6 October, 2026
    originally posted on Seed Health
    Image

    When I got it I

    When I got it I was very skeptical, it too a few days. I feel so much better weight wise, less lethargic, and mentally focus.
    Desiree
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    6 October, 2026
    originally posted on Seed Health
    Image

    I’ve been taking DS-01 daily

    I’ve been taking DS-01 daily synbiotic for several months and have noticed an overall improvement in not only my digestion, but my skin and hair health as well. My energy level seems more even throughout the day as well. Great stuff!
    James S.
    Did you find this review helpful?
    4 out of 5 stars
    6 October, 2026
    originally posted on Seed Health
    Image

    Started this for immune support

    Started this for immune support and regularity. I noticed a difference after the first month. I started with 1 for the first week and increased to 2 after. I take 2 every night before bed now. I used to take 2 in the morning but it made me really nauseous. I can definitely tell a difference when I don't take it.
    Linda
    Did you find this review helpful?
    5 out of 5 stars
    6 October, 2026
    originally posted on Seed Health
    Image

    I have been on this

    I have been on this for 2 years now and I can definitely tell there’s a change in my digestion and elimination for the better
    Jolene
    Did you find this review helpful?
    5 out of 5 stars
    6 October, 2026
    originally posted on Seed Health
    Image

    Here's a detailed accounting of

    Here's a detailed accounting of my experience on DS-01. Symptoms: I have clinically diagnosed acid reflux and take omeprazole for it daily. It is managed but have the expected triggers like eating too much, tomatoes, spicy food and more. Additionally, I have self diagnosed lactose intolerance. That said, I eat cheese and yogurt on a regular basis, and depending on the quantity it is not an issue. But a fast food milkshake or a double scoop of ice cream and I'll be running for the bathroom within hours. I don't know if there is any clinical term for the unpleasant gurgly and reflux type feelings I frequently get eating too much sugar, but I don't listen to my body on that one as I love cake, pie, cookies and more. Finally, my stomach always seems to be doing something irritating. It is either hungry or full or gurgling or somewhere in between. I couldn't tell you the last time my stomach was in a neutral state. Plus, the constant and loud gas all day and night. It could get challenging and uncomfortable with significant bloating being in places like a theater or conference for work. What I've tried: At one point or another, I've tried all the over the counter stuff from Tums to anti-gas pills to lactose aiding tablets. For a while I was using Zypan and that helped digestion for a short while. Every time I try a probiotic I think, why did I buy this, it isn't doing anything except maybe the first day I felt better. Nothing I've tried has helped that much or would be considered a long term solution (except the probiotic). The best I have ever felt was for 20 minutes immediately after my colonoscopy last year. So Why Seed? At first I was skeptical because it is another probiotic & expensive, but I've never tried one that is a double capsule that claims to get all the way to the colon. It worked in Seed's favor that I had a promo through Capital One for significant cash back that persuaded me to try it (although that hasn't paid out yet). The First 10 days: That was different. My body felt sensations, sometimes moderate pain, and "bubbles" for a lack of a better term throughout my torso. During the first 2-3 days I thought about stopping for these feelings and the fact that really, really smelly poop was a side effect. But I stuck through it. Days 11-90: I'm at the tail end of this period right now and have reached a point to renew. What I've observed is less bloating discomfort. For me, that hasn't meant no gas, but it's been more manageable and more concentrated to the early morning and late night. There have been exceptions, but it has mostly been reliable that within 2-3 hours of taking my Seed in the morning I am ready to poop. Sometimes it's tiny, but I always feel better afterwards. There were a few weeks in here that I'd eat breakfast, feel uncomfortable and close to painful digestive feelings, then poop and feel great. Nearly every time after my morning poop I get hungry. During occasions in which I ate too much, in the past I would easily not be hungry until late morning or even lunch. On Seed I've found much better overnight digestion and have woken up hungry on many mornings where that was not previously the case. Another side benefit has been better lactose tolerance, although I've not pushed the limits and eaten things from my past which have caused major issues. A couple of unadvertised surprises for you. I'm using less toilet paper as ejections are pretty clean and I'm finding my poop to not be smelly. Final Thoughts: It's not magic. I have not gained 80% stomach neutrality which would be a dream, but it has made working out a bit easier due to less food based stomach agitation. I used to always have to exercise on a near empty stomach to avoid major cramps. Most days pooping requires a fair bit of effort, but once done, there is a sense of relief. Foods that are naturally constipating, will still be, like rice, but I've found my body tolerates that better and I get something out the next day. What I don't like: -The size of the pills. They are large but do swallow easier than expected in water. -I feel like I'm hungry more often and have possibly gained weight as a result. It is hard to say as there have been other circumstances likely contributing to possible weight gain since I began my Seed regimen, but I'm keeping an eye on this. -It is unclear if the product will continue working for me or if its effectiveness will fade over time. For now, good luck to anyone else whose stomach is their least favorite organ and I hope Seed helps you too.
    Alan W.
    Did you find this review helpful?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    5 October, 2026Verified purchase

    NOT Histamine Friendly

    I've taken many probiotics and never had issues. I started these at a low dose (1 daily) before going to two daily. Even just on one, I started breaking out in hives any time I got hot (working out became a nightmare). I didn't connect it to this at first until it hit me. I stopped taking these and within 48 hours no more issues. While this may not be an issue for everyone, just want others to be aware.
    B
    Did you find this review helpful?
    5 out of 5 stars
    5 October, 2026
    originally posted on Seed Health
    Image

    the best supplement for gut

    the best supplement for gut health! it helps so much with my bloating, digestion, and bowel health. I definitely feel a difference if I miss a few doses
    shania
    Did you find this review helpful?
    5 out of 5 stars
    5 October, 2026
    originally posted on Seed Health
    Image

    Seed is one of the

    Seed is one of the best products I’ve ever found to help support my microbiome. I do all I can to avoid antibiotics. After having to take one almost a year ago, I used Seed to get me back to balance. I immediately saw results, the best being regularity. I love the quality and consistency of this product. It delivers on their promise. Practice self care by taking Seed, you’ll be glad you did.
    Susan F.
    Did you find this review helpful?
    5 out of 5 stars
    5 October, 2026
    originally posted on Seed Health
    Image

    I’ve definitely noticed changes since

    I’ve definitely noticed changes since taking Seed Probiotic and multivitamin. The most noticeable change has been with bloating. The constant bloating has significantly reduced by A LOT! and bowels seem to be a bit more regulated, still no great but definitely seeing changes. It’s only been two months since taking them consistently so I look forward to seeing more results!
    Adriana
    Did you find this review helpful?
    1 out of 5 stars
    5 October, 2026
    originally posted on Seed Health
    Image

    Stopped subscription and shipments still

    Stopped subscription and shipments still continued
    Catherine M.
    Did you find this review helpful?
    5 out of 5 stars
    5 October, 2026
    originally posted on Seed Health
    Image

    The best - I feel

    The best - I feel it when I don’t take it! This helps so much
    Joselin L.
    Did you find this review helpful?
    5 out of 5 stars
    4 October, 2026
    originally posted on Seed Health
    Image

    Love

    I wasn’t sure how I would react to these but no issues and I got compliments on my complexion as well , did not realize that these capsules also had that added benefit ? I’m sold and am on my second month . Wonderful product
    Michelle B.
    Did you find this review helpful?
    5 out of 5 stars
    4 October, 2026
    originally posted on Seed Health
    Image

    I've used almost a month

    I've used almost a month and my bowl movements have become a little more consistent.
    Rebecca
    Did you find this review helpful?
    5 out of 5 stars
    4 October, 2026
    originally posted on Seed Health
    Image

    I am obsessed. Ive referred

    I am obsessed. Ive referred so many people to this probiotic. Its worth every penny. Its the only thing that's helped me.
    Holly D.
    Did you find this review helpful?
    5 out of 5 stars
    4 October, 2026
    originally posted on Seed Health
    Image

    So good for the gut.

    So good for the gut. I love this. No bloating, keeps you regular and is gentle.
    Shana
    Did you find this review helpful?
    5 out of 5 stars
    4 October, 2026
    originally posted on Seed Health
    Image

    The only probiotics I’ve noticed

    The only probiotics I’ve noticed that make a difference! Help keep me regular, but if taken first thing in the morning I will get a stomachache so I do make sure to take 20 minutes before or 3 hours after eating
    Chloe
    Did you find this review helpful?
    5 out of 5 stars
    3 October, 2026
    originally posted on Seed Health
    Image

    Finally! I'm a clean eater

    Finally! I'm a clean eater and focus on whole foods, including daily fiber and protein intake, and also exercise 5-6 days a week. In addition, I drink plenty of water. Despite all my efforts, I still was having a hard time producing regular Ideal bowel movements. Seed's DS-01 has been a game changer. Unfortunately, with daily use, the cost adds up. Wish there was a less expensive alternative.
    K. M.
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    3 October, 2026
    originally posted on Seed Health
    Image

    Absolute game changer - gut

    Absolute game changer - gut normalizes, eczema challenges stabilize and more easily resolve, and body feels more in tune with itself. Try it, it's worth the trial to appreciate becoming a member is worth it!
    Avi
    Did you find this review helpful?
    5 out of 5 stars
    3 October, 2026
    originally posted on Seed Health
    Image

    I love this supplement! If

    I love this supplement! If I forget to take it I can definitely tell a difference. It’s been a game changer!
    Mattie
    Did you find this review helpful?

    Get top deals, latest trends, and more.