Target New ArrivalsChristmasGift IdeasHoliday Kids CatalogHome & DecorToys & GamesElectronics & TechVideo GamesGift CardsClothing, Shoes & AccessoriesGroceryBabyBeautyTarget Beauty StudioPersonal CareHousehold EssentialsHealthWellnessBooks, Music & MoviesSports & OutdoorsPetsSchool & Office SuppliesParty SuppliesAutomotiveTarget OpticalClearanceNew ArrivalsChristmasGift IdeasTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Seed Daily Synbiotic Probiotic Capsules - 60ct - 2 of 4Seed Daily Synbiotic Probiotic Capsules - 60ct - 3 of 4Seed Daily Synbiotic Probiotic Capsules - 60ct - 4 of 4
Seed Daily Synbiotic Probiotic Capsules - 60ct - 1 of 4

Seed Daily Synbiotic Probiotic Capsules - 60ct

46 Questions
$44.99 reg $59.99
$15 off ends today

In Stock

Eligible for registries and wish lists
Save 5% every day
With Target Circle™ Card (restrictions apply)

At a glance

About this item

Highlights

  • DS-01® Daily Synbiotic is a 24-strain probiotic + prebiotic clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and strengthening the gut barrier.°
  • 60 vegan capsules (30 day supply). Take 2 capsules daily, with or without food. No refrigeration necessary. 53.6 billion AFU.
  • Proprietary ViaCap® technology safeguards probiotics through digestion to the colon for optimal results.°
  • 24 probiotic strains not found in most foods, yogurts, and beverages, and a polyphenol, non-fiber prebiotic from Indian pomegranate.
  • DS-01® has been validated in the largest clinical trial for a probiotic on bloating and gas in healthy adults°µ and studied in multiple randomized placebo control trials.
  • Extensively third-party tested for safety, strength, purity, heavy metals, pesticides, and allergens.
  • µAs of February 2026. In a randomized placebo-controlled trial on DS-01® Daily Synbiotic, n=350, Allegretti et. al, 2026.

Description

You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. The gut microbiome is connected to various organ systems and pathways throughout the body that are crucial for your health. In a healthy state, the gut microbiome carries out a multitude of functions like regulating digestion, enhancing nutrient absorption, and strengthening immune responses.

Seed’s flagship DS-01® Daily Synbiotic is a probiotic and prebiotic developed for whole body health, grounded in science with a deep understanding of the complex interactions within the microbiome. DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and strengthening the gut barrier.°

It contains 24 scientifically studied probiotic strains not commonly found in foods, yogurts, and beverages, and a polyphenolic, non-fiber prebiotic from pomegranate.

Proprietary capsule-in-capsule technology is intentionally engineered to safeguard probiotics through digestion, promoting survivability from stomach acid, digestive enzymes, moisture, and heat.*

Extensively third-party tested for safety, strength, purity, heavy metals, pesticides, and allergens.

Each jar contains 60 capsules, providing a 30-day supply of 53.6 billion AFU per dose with no refrigeration required.

*Based on a study conducted in SHIME®. Results may vary.
°These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Contains: Does Not Contain Any of the 9 Major Allergens
Suggested Age: 18 Years and Up
Product Warning: Consult a doctor if you are pregnant or nursing, keep out of reach of children
Product Form: Capsule
Package Quantity: 60
Colony forming units (billions): 0
Active fluorescent units (billions): 53.6
TCIN: 91816039
UPC: 860340001620
Item Number (DPCI): 094-02-5724
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Amount Amount Per Serving

% Daily Value*
Digestive Health Probiotic Blend 206mg
Micronutrient Synthesis Probiotic Blend 46mg
Dermatological Health Probiotic Blend 37mg
Cardiovascular Health Probiotic Blend 18mg
MAPP Microbiota-Accessible Polyphenolic Precursors 400mg
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

acid-resistant vegan outer [chlorophyllin] and inner [hypromellose, water] capsules, organic rice fiber, organic rice extract blend.

Allergens & Warnings:

If you are attempting to become, or are pregnant or nursing, consult your healthcare provider before use. Keep out of reach of children. Do not use if seal is broken.

Shipping details

Estimated ship dimensions: 2.87 inches length x 2.91 inches width x 3.45 inches height
Estimated ship weight: 0.54 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: is it possible for men to pop this pill?

submitted by Ktwo - 2 years ago
  • A: Thanks so much for reaching out! DS-01® Daily Synbiotic is a 2-in-1 probiotic and prebiotic, formulated for adults ages 18+. The DS-01® formula contains 24 clinically and scientifically studied probiotic strains and a polyphenol-based prebiotic, for benefits in and beyond the gut. The probiotic strains in the DS-01® formula have been backed by 16 strain-specific, published human studies as well as 13 in vitro/ex vivo mechanistic studies to indicate benefits for gastrointestinal function, gut barrier integrity, cardiovascular health, gut immune function, micronutrient synthesis, and dermatological health.

    submitted bySeed Team - 2 years ago
    Brand expert

Q: I have diverticulosis would this help?

submitted by Yvette - 2 years ago
  • A: DS-01® Daily Synbiotic isn’t intended to treat, diagnose, prevent or cure any condition or disease, including diverticulosis. Therefore, we’re unable to comment on its safety, suitability, or efficacy in this specific context. For those with pre-existing conditions, we always suggest an informed conversation with a healthcare provider who may advise on the addition of DS-01® given your health history. For context, DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and supporting the gut barrier. If you’d like to learn more, you can check out our website or reach out directly.

    submitted bySeed Team - 5 months ago
    Brand expert

Q: Hard to swallow? I have problems with large caps and these look large.

submitted by Nansky - 2 years ago
  • A: Yes this is a big concern for me too hope you will show size of pill.

    submitted bystoragelessshopper - 1 year ago
  • A: I only swallow with food and these are not bad. Pretty standard size.

    submitted byFmz - 2 years ago
  • A: Thanks so much for your question! Our DS-01® Daily Synbiotic capsule is size 00—that’s 0.917 inches long with a diameter of 0.322 inches, to be exact. We wouldn't recommend opening or tampering with the DS-01® Daily Synbiotic capsules in any way, as our ViaCap® is especially designed to ensure the bacteria stay alive through digestion and make it to the colon. That said, you may certainly try experimenting with how you may be able to tolerate the capsules—any method in which you can preserve the 2-in-1 ViaCap® capsule would be perfectly fine. Please reach out to care@seed.com with any additional questions!

    submitted bySeed Team - 2 years ago
    Brand expert

Q: How many pills per day are recommended?

submitted by Judy - 9 months ago
  • A: The daily dosage for DS-01® is two capsules per day (which includes 53.6B AFU + 400mg Indian Pomegranate). DS-01® can be taken any time of day—consistent daily intake is most important. We generally recommend taking the capsules together, but feel free to space it out if that works better for your routine.

    submitted bySeed Team - 9 months ago
    Brand expert
  • A: The directions inside the package say to take 1 pill a day for 3 days and then 2 pills a day thereafter.

    submitted byJaycee - 9 months ago

Q: Are these safe for people with shellfish allergies

submitted by Kooka - 2 years ago
  • A: DS-01® is not formulated with shellfish. Seed conducts comprehensive allergen testing on all of our products, including all 14 classes of allergens defined by the European Food Safety Authority (EFSA). That said, we always encourage a discussion with an allergist or healthcare provider to confirm the appropriateness of our product for those with concerns, sensitivities, or allergies. You can view the full product label with all ingredients here: https://seed.com/reference/syn-wk

    submitted bySeed Team - 5 months ago
    Brand expert

Q: Is this helpful for microscopic colitis

submitted by Mo - 11 days ago
  • A: Great question! DS-01® Daily Synbiotic isn’t intended to treat, diagnose, prevent or cure any condition or disease, including microscopic colitis. Therefore, we’re unable to comment on its safety, suitability, or efficacy in this specific context. For those with pre-existing conditions, we always suggest an informed conversation with a healthcare provider who may advise on the addition of DS-01® given your health history. For context, DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and supporting the gut barrier. If you’d like to learn more, you can check out our website or reach out directly.

    submitted bySeed Team - 10 days ago
    Brand expert

Q: Does this help with skin issues

submitted by Sad - 24 days ago
  • A: While DS-01® Daily Synbiotic is formulated with a prebiotic that is clinically studied to improve visible signs of skin aging, it is not specifically intended to treat, prevent, or cure any pre-existing skin conditions. Given this, we’re unable to comment on its suitability or efficacy in that regard. For context, DS-01® is clinically validated to improve regularity, reduce bloating, and alleviate gas by transforming the gut microbiome and supporting the gut barrier. If you’d like to learn more, you can explore the research behind DS-01® here: https://seed.com/reference/syn-wk If you have any questions, we always suggest an informed conversation with a healthcare provider, who can advise on the addition of any new supplement given your health history.

    submitted bySeed Team - 24 days ago
    Brand expert

Q: Is this eligible for OTC benefit ?

submitted by Ow - 2 months ago
  • A: Great question! We don’t currently accept FSA/HSA cards directly for that product. However, we partner with TrueMed to support reimbursement. Here’s how it works: 1. Complete TrueMed’s quick evaluation [https://app.truemed.com/qualify/tm_qual_juyb1w4lmo] ($12 fee, FSA/HSA eligible). 2. If eligible, TrueMed will email you a Letter of Medical Necessity. 3. Submit your LMN and Seed receipt(s) to your FSA/HSA provider for reimbursement. Receipts can be downloaded anytime in your Seed Account under Order History. Please don't hesitate to send our Care team an email at care@seed.com with any other questions, and we'll be happy to help!

    submitted bySeed Team - 2 months ago
    Brand expert

Q: What strains of probiotics does this contain and how much of each?

submitted by Manteca Man - 2 months ago
  • A: Great questions! You can find our complete strain list and included ingredients here: https://seed.com/reference/syn-wk#label-101

    submitted bySeed Team - 2 months ago
    Brand expert

Q: What are the ingredients?

submitted by Lijon - 2 months ago
  • A: Thanks for reaching out! DS-01® is a 2-in-1 prebiotic and probiotic that combines 24 select bacterial strains and a non-fiber polyphenol prebiotic compound: punicalagins, which is sourced from Indian Pomegranate. You can find our complete strain list and included ingredients here: https://seed.com/reference/syn-wk#label-101

    submitted bySeed Team - 2 months ago
    Brand expert

Additional product information and recommendations

Discover more options

Skip to next section

Frequently bought together

Skip to next section

This item is featured in

Guests also viewed

Skip to next section

Guests are saying

Guests have experienced significant improvements in their gut health and overall well-being after using this daily synbiotic. Many have noted enhanced digestion, reduced bloating, and increased energy levels. The product is praised for its high quality, effective formulation, and beautiful packaging. Guests appreciate the convenience of the travel container and the positive changes they have observed in their skin and immune system. Overall, it has become an essential part of their daily wellness routine.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.8 out of 5 stars with 29377 reviews
    67% would recommend
    62 recommendations
    5 out of 5 stars
    31 October, 2026
    originally posted on Seed Health
    Image

    This really is one of

    This really is one of the best probiotic supplements on the market. I love that it comes packaged in a glass bottle and with recyclable everything else. I love that there are a good variety of clinically studied strains of probiotics along with prebiotics. Even some higher end probiotics out there don't include the number and actually verified clinically studied strains that this one does. It is also reasonably priced for what you get and I seemed to handle it okay even with a sensitive system. Definitely something I want to use on the regular, budget accommodating.
    GP
    Did you find this review helpful?
    5 out of 5 stars
    31 October, 2026
    originally posted on Seed Health
    Image

    Significant reduction of bloating and

    Significant reduction of bloating and discomfort after prolonged use of Seed.
    Natalie
    Did you find this review helpful?
    5 out of 5 stars
    31 October, 2026
    originally posted on Seed Health
    Image

    Guaranteed to go to the

    Guaranteed to go to the bathroom when you take this.
    AZ
    Did you find this review helpful?
    5 out of 5 stars
    31 October, 2026
    originally posted on Seed Health
    Image

    I have always had an

    I have always had an issue with bloating and being very irregular. Laxatives were the only thing that helped. I decided to try Seed. I didn’t make a huge difference till around the third month. It works great! I am glad I stuck with it and it has made a huge difference.
    Mary
    Did you find this review helpful?
    5 out of 5 stars
    31 October, 2026
    originally posted on Seed Health
    Image

    I have been taking this

    I have been taking this for a while now and it works great for my system. I turned my hubby on to it now, and he is doing great on it as well. Great product!
    KImberly D.
    Did you find this review helpful?
    5 out of 5 stars
    30 October, 2026
    originally posted on Seed Health
    Image

    The first month my bm

    The first month my bm were more frequent and experienced a lot less bloating. After months of using I felt better and better! I highly recommend it if you have IBS-C.
    Julia
    Did you find this review helpful?
    4 out of 5 stars
    30 October, 2026
    originally posted on Seed Health
    Image

    When I first started taking

    When I first started taking these I noticed a difference as to how I was feeling. I recognized less bloating feeling and I've had less stomach issues since taking these DS-01 pills. I've been taking them for a little while and don't really see/feel a lot of differences now but maybe I'm just feeling the new normal so I don't notice too much differences at this point. I wish it helped more with more frequent/easier bowl movements but it hasn't affected me in that way unfortunately.
    Cheryl
    Did you find this review helpful?
    5 out of 5 stars
    30 October, 2026
    originally posted on Seed Health
    Image

    I started with this produce

    I started with this produce several months back , my daughter introduced me to it, I tried it for a month, and I saw results. I went to my GI Dr, I have always had issues in that area. He had turned me toward a prescription probiotic instead; which I have been on for 4months as of today, it seems to have made things worse, and slowed things down . So I have decided to stop the prescription, and I have order Seed again.
    LA
    Did you find this review helpful?
    5 out of 5 stars
    30 October, 2026
    originally posted on Seed Health
    Image

    I tend to have a

    I tend to have a sensitive gut and decided to give these a try. They have made me regular plus they didn’t bother my stomach once I adjusted!
    Colette
    Did you find this review helpful?
    5 out of 5 stars
    30 October, 2026
    originally posted on Seed Health
    Image

    I found this to be

    I found this to be quite gentle and effective. Definitely worth trying to decide if it works for your routine.
    Jane
    Did you find this review helpful?
    4 out of 5 stars
    30 October, 2026
    originally posted on Seed Health
    Image

    This is great! I love

    This is great! I love that it comes in refills and that the glass jar can be reused. The subscription makes it easy to keep up the refills.
    April
    Did you find this review helpful?
    5 out of 5 stars
    30 October, 2026
    originally posted on Seed Health
    Image

    I have been on seed

    I have been on seed for 3 months now and overall my digestion and bloating have gone down significantly.
    Mandy
    Did you find this review helpful?
    5 out of 5 stars
    30 October, 2026
    originally posted on Seed Health
    Image

    been taking this for a

    been taking this for a year now. after 2 months of taking it, i definitely felt the difference in how i was going to the bathroom
    Nicole
    Did you find this review helpful?
    5 out of 5 stars
    30 October, 2026
    originally posted on Seed Health
    Image

    Amazing for the Gut, it’s

    Amazing for the Gut, it’s the only probiotic and prebiotic I will use! It has made my skin more clear and my digestive system on a routine. clean ingredients and just overall the best.
    Natalie N.
    Did you find this review helpful?
    5 out of 5 stars
    30 October, 2026
    originally posted on Seed Health
    Image

    It took me a week

    It took me a week to acclimate from my former raw probiotic to this one but once I did my body has consistently responded well.
    Mona
    Did you find this review helpful?
    1 out of 5 stars
    29 October, 2026
    originally posted on Seed Health
    Image

    I could not swallow the

    I could not swallow the capsules, I am accumulating more every month and I cannot find a way to cancel a subscription I didn’t agree with in the first place.
    Daniela W.
    Did you find this review helpful?
    5 out of 5 stars
    29 October, 2026
    originally posted on Seed Health
    Image

    SEED has been a game

    SEED has been a game changer for me! After years of dealing with bloating, stomach pain, and constipation, I’m finally feeling relief. It took about a month to really notice the difference, but now my bloating and stomach pain are gone, and I’m having daily bowel movements instead of only once every 5–7 days. This has been a tremendous improvement in my quality of life, and I’m so glad I gave it time to work!
    Linton
    Did you find this review helpful?
    5 out of 5 stars
    29 October, 2026
    originally posted on Seed Health
    Image

    I am thinking this probiotic

    I am thinking this probiotic is already taking effect because I have not had a bm in approx. 8 days and as soon as I receive these, I took one and then one more the next day and I was going to the bathroom and then again the next morning !
    Debbie
    Did you find this review helpful?
    5 out of 5 stars
    29 October, 2026
    originally posted on Seed Health
    Image

    I have been taking Daily

    I have been taking Daily Synbiotic for about 4 years and I plan on continuing. I have made referrals to 3 friends and they all have shared similar feedback: better digestion, no acid reflux and overall get sick less with stronger immune system.
    Alison
    Did you find this review helpful?
    5 out of 5 stars
    29 October, 2026
    originally posted on Seed Health
    Image

    This product has completely changed

    This product has completely changed my life. I used to have a hard time going to the bathroom and get constipated. I am regular and go every day now!
    Laura
    Did you find this review helpful?

    Get top deals, latest trends, and more.