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Systane Complete Lubricant Eye Drops - 2 of 4Systane Complete Lubricant Eye Drops - 3 of 4Systane Complete Lubricant Eye Drops - 4 of 4
Systane Complete Lubricant Eye Drops - 1 of 4

Systane Complete Eye Drops - 10ml/2ct

20 Questions
$22.49 ($33.57/fluid ounce)
Count10ml/2ct

In Stock

Eligible for registries and wish lists
Save 5% every day
With Target Circle™ Card (restrictions apply)

At a glance

About this item

Highlights

  • Our most advanced formula ever, designed to provide relief for all major types of dry eye (aqueous deficient, evaporative/lipid deficient and mixed)
  • 8 hours of long-lasting relief
  • Fast-acting hydration
  • Tear evaporation protection

Description

Systane Complete is the simple choice for every major type of dry eye, especially effective against evaporative dry eye. Get lasting and fast relief from dry-eye symptoms with these Complete Eye Drops from Systane. These lubricating eyedrops instantly provide soothing relief from inflammation, dryness, redness and itchiness, letting you go about your day more comfortably. These eyedrops for dry eyes help prevent tear evaporation, keeping your eyes moist to prevent further drying. With nano droplets for better coverage, these eyedrops will help you enjoy clearer vision by soothing heavy eyes, irritation and fatigue. Designed for mild to moderate dry eye sufferers, Systane Complete dry eye drops help provide up to 8 hours of relief in just one drop. It is safe for use with soft contact lenses, but it is not a rewetting drop, making it a convenient solution for everyday eye care.
Suggested Age: 18 Years and Up
Health Facts: Paraben-Free, Dye-Free
Product Form: Drops
Primary Active Ingredient: Propylene Glycol
Package Quantity: 2
Contact Lens Type: Silicone Hydrogel, Gas Permeable, Soft
TCIN: 75002751
UPC: 300650481113
Item Number (DPCI): 245-09-0182
Origin: Assem USA w/foreign/dom. parts
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

propylene glycol(0.6%).

Purpose

Lubricant..

When using this product

When using this product : do not touch tip of container to any surface to avoid contamination,replace cap after each use.

Stop use and ask a doctor if you experience any of the following:

Stop use and ask a doctor if you experience any of the following:: eye pain,changes in vision,continued redness or irritation of the eye,condition worsens or persists for more than 72 hours.

Directions

Shake well before using. Put 1 or 2 drops in the affected eye(s) as needed.

Other information

Store at room temperature.

Inactive ingredients

boric acid, dimyristoyl phosphatidylglycerol, edetate disodium, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate , polyquad (polyquaternium-1) 0.001% preservative, sorbitan tristearate, sorbitol and purified water, may contain hydrochloric acid and/or sodium hydroxide to adjust ph

Question or comments?

800-757-9195

Shipping details

Estimated ship dimensions: 4.48 inches length x 2.63 inches width x 1.29 inches height
Estimated ship weight: 0.09 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: Can you use this product on infants (10months) ?

submitted by Mariana - 3 years ago

  • A: We recommend consulting with a doctor for use younger than 3 years of age. Thank you for your interest in Systane!

    submitted byAlcon Product Expert - 3 years ago
    Brand expert

Q: Do they cause bleach like stains on your face where the drops run down on your face, and under your eye as Refresh brand drops do?

submitted by diane - 3 months ago

  • A: Systane Complete Lubricant Eye Drops are not known to cause bleach-like staining on the skin around the eyes or face. If any eye drop runs onto the skin, we recommend gently wiping away excess liquid and allowing the area to dry. If you experience discoloration, irritation, or any unexpected effects, please discontinue use and consult your eye care professional. Thanks for your interest in Systane!

    submitted byAlcon Product Expert - 3 months ago
    Brand expert

Q: how do these differ from Optive refresh eyedrops

submitted by DJ - 4 months ago

  • A: Systane® COMPLETE and Refresh Optive™ are both lubricant eye drops that help relieve dry eye symptoms, but they use different formulations. Systane® COMPLETE is designed to provide hydration and support all layers of the tear film, including the lipid (oil) layer, which can help reduce tear evaporation. Thanks for your interest in Systane Complete!

    submitted byAlcon Product Expert - 4 months ago
    Brand expert

Q: Are these drops Preservative Free?

submitted by bobo - 6 months ago

  • A: These specific drops are not Preservative-Free. Systane Complete is available in a Preservative-Free option in a multi-dose bottle or single use vials, stated in the product description or look for the blue strip at the top of the package. Thanks for your interest in Systane Complete!

    submitted byAlcon Product Expert - 6 months ago
    Brand expert

Q: I'm looking for systane with oil not water is this the right one?

submitted by KJ - 7 months ago

  • A: Yes, SYSTANE® Complete Eye Drops are the right one! This formula contains nano‑lipid (oil‑based) droplets designed to help stabilize the tear film and relieve dry eye symptoms, including those related to tear evaporation. Unlike water‑only drops, SYSTANE® Complete works across all layers of the tear film, making it a good option if you’re looking for a drop with oil‑based lubrication. Thanks for your interest in Systane Complete!

    submitted byAlcon Product Expert - 7 months ago
    Brand expert

Q: Are these preservative free?

submitted by Grandma Diane - 10 months ago

  • A: These particular drops are not preservative free, but if you search Systane Complete Preservative Free, there is a multi-dose bottle and single use vials that are both preservative free. Thanks for your interest in Systane!

    submitted byAlcon Product Expert - 9 months ago
    Brand expert

Q: What’s the difference between ULTRA and COMPLETE?

submitted by DryI - 10 months ago

  • A: Systane Ultra is excellent for quick dry eye relief, while Systane Complete is a more advanced formula to address all types of dry eye, including dry eye caused by tear evaporation or low tear production. Systane Complete also lasts longer, up to 8 hours. Thanks for your interest in Systane!

    submitted byAlcon Product Expert - 10 months ago
    Brand expert

Q: can you use with contact lenses?

submitted by Learned - 11 months ago

  • A: We recommend inserting the drops before or after contact lens usage to allow the eye drop to properly coat your eye. One drop will last 8 hours! Thank you for your interest in Systane!

    submitted byAlcon Product Expert - 11 months ago
    Brand expert

Q: Is Systane Complete optimal dry eye relief lunricant eye drops preservitive free?

submitted by Tom c - 11 months ago

  • A: Systane Complete is available in both Preserved or Preservative Free. This particular SKU is the preserved item. Thanks for your interest in Systane!

    submitted byAlcon Product Expert - 11 months ago
    Brand expert

Q: Today is Oct 10, 2024. What's the expiration date of this product?

submitted by Adia - 2 years ago

  • A: Each item is shipped to Target with a 24-month shelf life. The individual unit's expiration date is unique to the item and when it was made, it is normally located on the bottom of the box. In the rare case that you receive an expired product, please accept our apology, and return it to the customer service desk for a refund. Thank you for your interest in Systane!

    submitted byAlcon Product Expert - 2 years ago
    Brand expert
See all questions (20)

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Amazing relief

These are the best eye drops I have ever used, I have been visiting family and got sick, so I have been staying in a house with smokers, my eyes were so dry and irritated and the dry eye drops that I was using were not working, it only took 2 days for me to get relief using these drops, they are amazing.
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The packaging is horrible.I can never get the bottle to dispense drops.Shouldnt be this difficult .Waste of money.

squeeze bottle
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Helpful Hydration For My Eyes

These eye drops hydrate my eyes all day and all night. I use them twice daily.
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21 July, 2026Verified purchase

Recommended by specialist

I have extremely dry uncomfortable eyes and my eye specialist suggested Systane Complete Lubricant eye drops. It’s supposed to work on several causes of dry eyes. I use the drops throughout the day and keep bottles of it in different places. While it doesn’t cure or eliminate my extreme dry eyes, it does help me get through the day. It is expensive for such a small bottle, so I try to get it when it’s on sale or a Target Circle deal.
Gramma932
quality: 5 out of 5
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18 June, 2026Verified purchase

Great Smaller Drops

I love the Systane nano drips. The smaller drops are night to keep my eyes moist for many hours.
Marilyn W
quality: 1 out of 5
value: 1 out of 5
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5 out of 5 stars
25 April, 2026Verified purchase

(no review title)

Great, less dry eye symptoms
Sharyn
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4 out of 5 stars
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3 April, 2026

(no review title)

Works well for my dry eyes
Broken Box
quality: 4 out of 5
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1 out of 5 stars
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22 March, 2026Verified purchase

(no review title)

Item came completely open
Katie
quality: 1 out of 5
value: 1 out of 5
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1 out of 5 stars
17 March, 2026

(no review title)

Dried my eyes out. Very disappointed Going to try the preservatives free one
Mom
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1 out of 5 stars
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26 February, 2026Verified purchase

(no review title)

Not that great. I don't feel any difference while using for dry eyes. within minutes I could reapply. The worst part of the product is the application dropper, it's no different than the one used for nail glue. I fear it near my eyes and double check the label even though I know I don't have nail glue in my house. I cannot believe they deem this safe for use! I've gone back to Blink 3 in 1, much better product and better applicator.
Rach33
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3 out of 5 stars
14 February, 2026Verified purchase

(no review title)

Ok but I still have blurring and stinging eyes 30 min later.
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23 January, 2026Verified purchase

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These drops may be OK for some, but they irritated my eyes and we’re actually painful. I ended up ordering preservative free drops and those are much better.
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Just what I needed

My new eye doctor recommeded this and in just one week I can feel the difference in comfort and clarity of vision. Target had the best price and fast delivery.
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28 September, 2025Verified purchase

comfortable eyes

These were recommended by my opthamologist. They work quite well. If you use a computer screen or just have dry eyes, this product is excellent to help soothe the irrittion.
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24 July, 2025Verified purchase

Good solution for dry eyes

Really helps with my dry eyes
Heather S
quality: 5 out of 5
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5 out of 5 stars
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15 July, 2025Verified purchase

Must Buy

After lasik my eyes became very dry. These help tremendously out of all I've tried.
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3 out of 5 stars
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13 March, 2025Verified purchase

Just ok

Decided to try a different eye drop out of curiosity and chose this one because of the reviews. Unfortunately, it's not working out as well as I'd hoped. It works only very temporarily for me so far after trying it out for a few days. My biggest issue with it is using it at night, because I wake up with red eyes feeling like it's doing the opposite effect. During the day, however, it seems to be ok. I typically use the BioTrue Hydration Boost eye drops, and those work great for me. Was curious if there was anything better out there, but these drops just aren't doing it for me.
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Great for red dry eyes

These were recommended by my doctor because my eyes were always feeling dry and uncomfortable. A bit pricey but they definitely have helped. I use it about twice a day. One or two drops will do.
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Well in eyes!

It works well keeping me from dry eye.
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