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Enfamil Optimum Enspire Ready to Feed Infant Formula - 32 fl oz: Brain Development, Growth Support, Immune System Support - 2 of 4Enfamil Optimum Enspire Ready to Feed Infant Formula - 32 fl oz: Brain Development, Growth Support, Immune System Support - 3 of 4Enfamil Optimum Enspire Ready to Feed Infant Formula - 32 fl oz: Brain Development, Growth Support, Immune System Support - 4 of 4
Enfamil Optimum Enspire Ready to Feed Infant Formula - 32 fl oz: Brain Development, Growth Support, Immune System Support - 1 of 4

Enfamil Optimum Enspire Ready to Feed Infant Formula - 32 fl oz: Brain Development, Growth Support, Immune System Support

$15.99 ($0.50/fluid ounce)

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About this item

Highlights

  • NEW LOOK, SAME PREMIUM NUTRITION: Previously known as Enspire Optimum, Enfamil Optimum Baby Formula now has a refreshed look and name while offering the same trusted infant nutrition parents rely on.
  • OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum Ready-to-Feed includes two of the most abundant human milk oligosaccharides (HMOs)—2’-FL and LnNT.
  • SUPPORTS IMMUNE & BRAIN DEVELOPMENT: This ready-to-feed formula provides brain-building DHA and dual HMOs (2’-FL & LnNT) to nourish both cognitive and immune development in your growing baby.
  • TRUSTED NUTRITION FOR COMBO FEEDING: With key nutrients for growing babies, Enfamil Optimum gives parents the flexibility to supplement breastfeeding with our closest formula to breast milk.
  • NO MIXING, READY-TO-FEED: Enfamil Optimum ready-to-feed offers complete infant nutrition in a convenient, no-prep format—ideal for supplementing breast milk or feeding late at night, while traveling, and or on-the-go!
  • NO ARTIFICIAL ADDITIVES & NON-GMO: Has clinically-tested, non-GMO ingredients. Free from artificial growth hormones, colors, and flavors. Enfamil Optimum does not contain high fructose corn syrup and is made with milk sourced from the United States. Optimum is premium baby formula for infants through 12 months of age.
  • PEDIATRICIAN & PARENT TRUSTED: Enfamil is the #1 trusted infant formula brand by pediatricians* and parents of those who have a preference.
  • JOIN ENFAMIL FAMILY BEGINNINGS® & EARN REWARDS: Sign up for Enfamil Family Beginnings® to enjoy exclusive savings, expert tips, and personalized support—plus earn rewards with every eligible purchase.
  • CHOOSE A CASE PACK FOR ADDED CONVENIENCE: Stock up with a case pack of Enfamil formula to help ensure you’re always prepared—ideal for regular feedings and busy routines.

Description

Give your baby the best start with Enfamil Optimum Ready-to-Feed—our most advanced formula designed to support immune health and brain development, inspired by the composition of breast milk.

Enfamil Optimum includes a dual prebiotic blend—2'-FL and LnNT—two of the most abundant human milk oligosaccharides (HMOs) naturally found in breast milk, to help nourish your baby’s developing immune system. It also contains brain-building DHA to support early cognitive development.

Made without artificial growth hormones*, artificial colors, or flavors, Enfamil Optimum is a non-GMO† formula offering premium nutrition through 12 months of age.

Whether you're combo feeding or transitioning from breastfeeding, this ready-to-feed format offers both peace of mind and on-the-go convenience—no mixing or prep required.

Join Enfamil Family Beginnings® to earn rewards with every purchase and access exclusive benefits and support. Details: https://www.enfamil.com/baby-formula-coupons-samples/

SNAP eligible.

Serving Size: 5 fl oz

Amount :

Calories: 100
% Daily Value*
Protein 2.1g
Total Fat 5.3g
Total Carbohydrate 11.1g
Water 133g
Omega-6 (linoleic acid LA) 780mg
Vitamin A 300IU
Vitamin D 70IU
Vitamin E 2IU
Vitamin K 9mcg
Thiamin 80mcg
Riboflavin 140mcg
Vitamin B6 60mcg
Vitamin B12 0.3mcg
Niacin 1000mcg
Folic Acid 16mcg
Pantothenic Acid 500mcg
Biotin 3mcg
Vitamin C 12mg
Choline 24mg
Inositol 24mg
Calcium 78mg
Phosphorus 43mg
Magnesium 8mg
Iron 1.8mg
Zinc 1mg
Manganese 15mcg
Copper 75mcg
Iodine 15mcg
Selenium 2.8mcg
Sodium 27mg
Potassium 108mg
Chloride 63mg
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

water, nonfat milk, lactose, vegetable oil (contains one or more of the following: palm olein oil, coconut oil, soy oil, high oleic sunflower oil), and less than 2%: lacto-n-neotetraose#, 2'-fucosyllactose#, whey protein concentrate**, mortierella alpina oil††, schizochytrium sp. oil‡‡, potassium citrate, calcium carbonate, calcium chloride, magnesium phosphate, sodium chloride, calcium phosphate, ferrous sulfate, zinc sulfate, cupric sulfate, manganese sulfate, sodium selenite, potassium iodide, mono- and diglycerides, soy lecithin, ascorbic acid, sodium ascorbate, vitamin e acetate, niacinamide, calcium pantothenate, vitamin a palmitate, thiamin hydrochloride, riboflavin, vitamin b6 hydrochloride, folic acid, vitamin k1, biotin, vitamin b12, carrageenan, choline chloride, inositol, vitamin d3, taurine, l-carnitine. #a source of hmo (2'-fl & lnnt human milk oligosaccharides) **a source of mfgm (milk fat globule membrane composed of proteins and fats) components ††a source of arachidonic acid (ara) ‡‡a source of docosahexaenoic acid (dha)

Allergens & Warnings:

DO NOT USE IF PROTECTIVE SEAL AROUND CAP, OR IF FOIL SEAL UNDER CAP, IS DAMAGED OR MISSING., WARNING: Do not use a microwave oven to warm formula. Serious burns may result.
Features: No Artificial Colors
Dietary Needs: Naturally Flavored
Baby Formula Focus: Immune System Support, Brain Development, Growth Support
Base Ingredient: Milk
State of Readiness: Ready to Use
Form: Liquid
Package Quantity: 1
Age Stage: Infant
Net weight: 32 fl oz (US)
TCIN: 94051720
UPC: 300875135464
Item Number (DPCI): 007-09-0091
Origin: Made in the USA
Grocery Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers. Any additional pictures are suggested servings only.
If the item details aren’t accurate or complete, we want to know about it.

Shipping details

Estimated ship dimensions: 3.2 inches length x 3.5 inches width x 9.57 inches height
Estimated ship weight: 2.33 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest. If purchased online with SNAP EBT, this item must be returned within 90 days of the date it was shipped, delivered by a Shipt shopper, or made ready for pickup. This 90-day return window is required by SNAP.
See the return policy for complete information.

Q: Is the liquid version more potent than the powder? For some reasons my baby prefers the liquid premade ones. Also the liquid ones look darker than the powder version. Am I wrong?

submitted by Baby boy - 9 months ago

  • A: Hello Baby boy! Thank you for choosing Enfamil Optimum! We are sorry you had that experience and would like to get a little more information from you. Please give us a call at 1-800-222-9123, choose option 1, and reference #6906162. Thanks! Bev, Enfamil Expert

    submitted byEnfamil Customer Care - 9 months ago
    Brand expert

Q: Do you have to store this In the fridge after opening?

submitted by Lacy - 11 months ago

  • A: Hello, Lacy! Our opened or prepared liquid infant formulas can be kept covered in the refrigerator for up to 48 hours. -Katelin, Enfamil Expert

    submitted byEnfamil Customer Care - 11 months ago
    Brand expert

Q: Since this is missing the lactoferrin, what would be the difference with this and nueropro?

submitted by Ash - 1 year ago

  • A: Hello, Ash! Enfamil Optimum has naturally occurring MFGM (Milk Fat Globule Membrane) components and well as LnNT (Lacto-N-tetraose) HMO, components also found in breast milk. Enfamil NeuroPro Infant has naturally occurring MFGM components, however, it does not contain LnNT (Lacto-N-tetraose) HMO. LnNt primarily functions as a prebiotic, meaning it selectively nourishes beneficial bacteria in the infant's gut, promoting healthy gut development and potentially supports immune function. -Katelin, Enfamil Expert

    submitted byEnfamil Customer Care - 1 year ago
    Brand expert
See all questions (3)

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Guests are saying

This formula is highly praised by guests for its close resemblance to breast milk, making it an excellent choice for supplementing or transitioning from breastfeeding. Many guests appreciate its easy digestibility and the nutritional benefits it offers, including essential components like lactoferrin. The convenience of ready-to-use options is also highlighted, making it a practical choice for busy parents. Overall, it has been a reliable solution for many families seeking quality nutrition for their infants.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.8 out of 5 stars with 3472 reviews
    easy on tummy: 4 out of 5
    easy to prepare: 5 out of 5
    quality: 4.5 out of 5
    value: 4.5 out of 5
    66% would recommend
    3 recommendations
    5 out of 5 stars
    20 March, 2026
    originally posted on Enfamil
    Image

    Love the ingredients

    [This review was collected as part of a promotion.] This formula has worked great so far for my baby who had constipation on other formulas
    1 reply from Customer Care team - 11 days ago
    We appreciate your feedback regarding our product, Ah4000! Thank you for choosing Enfamil to help give your little one the best start in life! — Tasha, Enfamil Expert
    Ah4000
    Did you find this review helpful?
    5 out of 5 stars
    17 March, 2026
    originally posted on Enfamil
    Image

    Baby has adjusted after exclusive breast fed

    [This review was collected as part of a promotion.] Tried a generic substitute & baby had gas & constipation. Went back to Enfamil Optimum
    1 reply from Customer Care team - 15 days ago
    We at Enfamil are so glad you're a part of our family, Grammy Jo! Thanks for taking time to leave a review! — Abby, Enfamil Expert
    Grammy Jo
    Did you find this review helpful?
    5 out of 5 stars
    15 March, 2026
    originally posted on Enfamil
    Image

    My baby loves this formula

    [This review was collected as part of a promotion.] We went through multiple formulas in order to find one my baby liked and that didn’t upset her stomach. We tried similac 360 it was too harsh for her stomach. Then we switched to regular enfamil still too harsh. Finally we tried gentlease and that worked for about a month before she started refusing because of the taste. After some research we tried the enfamil optimum and my baby gulped it down. She has been eating it ever since.
    1 reply from Enfamil Customer Care team - 17 days ago
    Hello! We are happy to hear our Enfamil® Optimum™ is working out well for your little one! We appreciate your feedback and would like to learn more about your child’s experience using our formula. Please give us a call at 1-800-222-9123, choose option 1, and reference #8106261. Thanks! - Ayn
    Nish1991
    Did you find this review helpful?
    5 out of 5 stars
    13 March, 2026
    originally posted on Enfamil
    Image

    Great for on the go

    [This review was collected as part of a promotion.] Such an amazing option for all the go when I can’t make a bottle that is heated up
    1 reply from Customer Care team - 21 days ago
    We work hard to bring you the very best products. Thanks for leaving us a great review, Kristen! — Abby, Enfamil Expert
    Kristen
    Did you find this review helpful?
    5 out of 5 stars
    13 March, 2026
    originally posted on Enfamil
    Image

    Great product

    [This review was collected as part of a promotion.] I’ve been buying this for a few months and my babies has been enjoying it with very little spit up
    1 reply from Consumer Care Nutrition team - 18 days ago
    Hello Kristen! We are glad to hear that you have been enjoying using our Enfamil Optimum (Enspire)! If you have any further questions, please give us a call at 1-800-222-9123, choose option 1, and reference #8100611. Thanks! Maria, Enfamil Expert.
    Kristen
    Did you find this review helpful?
    5 out of 5 stars
    12 March, 2026
    originally posted on Enfamil
    Image

    Breast milk like formula

    [This review was collected as part of a promotion.] my baby was breastfeeding majority of his infant months and when we decided to switch i wanted something similar to breast milk and this is that!
    1 reply from Customer Care team - 22 days ago
    Thanks so much for sharing your experience with us, Kaye! — Abby, Enfamil Expert
    kaye
    Did you find this review helpful?
    5 out of 5 stars
    12 March, 2026
    originally posted on Enfamil
    Image

    Enfamil Enspire Formula

    [This review was collected as part of a promotion.] My coworker recommend Enfamil enspire formula so I decided to give my baby when my breastfeeding not enough and she still hungry. She likes it and stop crying.
    1 reply from Customer Care team - 22 days ago
    Thank you for sharing your experience using our product, Sarah! We appreciate your feedback! — Marcy, Enfamil Expert
    Sarah
    Did you find this review helpful?
    5 out of 5 stars
    6 March, 2026
    originally posted on Enfamil
    Image

    Easy on baby’s tummy

    [This review was collected as part of a promotion.] Bought as replacement to Similac total care baby had at the hospital and didn’t have tummy issue. Also, the convenience that I can just pour as little or as much I think he will need each feeding is a plus!
    1 reply from Customer Care team - 28 days ago
    We work hard to bring you the very best products. Thanks for leaving us a review, Lee! — Abby, Enfamil Expert
    Lee May
    Did you find this review helpful?
    5 out of 5 stars
    4 March, 2026
    originally posted on influenster.com
    Image

    The best investment for my baby's health.

    Great formula with premium ingredients like Lactoferrin. It's gentle on my baby's tummy and mixes easily without clumps. I feel confident knowing it supports brain development and immunity.
    1 reply from Customer Care team - 29 days ago
    We at Enfamil are so glad you're a part of our family, AnhT! Thanks for taking time to leave a review! — Tasha, Enfamil Expert
    AnhT
    Did you find this review helpful?
    4 out of 5 stars
    3 March, 2026
    originally posted on Enfamil
    Image

    Better ingredients

    [This review was collected as part of a promotion.] Has better ingredients than some. Gentle release doesn't have good ingredients
    1 reply from Consumer Care Nutrition team - 29 days ago
    Hello Bby1256! We are glad to hear that you have been enjoying using our Enfamil Enspire Optimum! If you have any further questions, please give us a call at 1-800-222-9123, choose option 1, and reference #8051178. Thanks! - Cess, Enfamil Expert
    Bby1256
    Did you find this review helpful?
    5 out of 5 stars
    28 February, 2026
    originally posted on Enfamil
    Image

    Absolutely love!

    [This review was collected as part of a promotion.] My supply started to dry up so I had to switch to formula. This is the closest I could get to breastmilk and it has been amazing. She loves it!
    1 reply from Customer Care team - 1 month ago
    We are so happy your little one is loving Enfamil, Steph617. Thank you for taking time to let us know! — Abby, Enfamil Expert
    Steph617
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    25 February, 2026
    originally posted on Enfamil
    Image

    Baby loves

    [This review was collected as part of a promotion.] Baby boy has been on this since he came home from the hospital, and loves it. I chose this one for its claims to have a key protein that’s found in breast milk. So I felt comfortable giving this to my son since I was unable to breastfeed. He’s now 6 weeks old, happy and thriving.
    1 reply from Customer Care team - 1 month ago
    We are thrilled that your son is doing well on our formula, Britt! Thanks for taking the time to let us know.- Tasha, Enfamil Expert
    Britt
    Did you find this review helpful?
    5 out of 5 stars
    23 February, 2026
    originally posted on Enfamil
    Image

    Tried and loved

    Bought this on a whim to try and my son loved this This and the infant formula and neuro pro are his favs
    1 reply from Customer Care team - 1 month ago
    We at Enfamil are so glad you're a part of our family, Shannen! Thanks for taking time to leave a review! — Abby, Enfamil Expert
    Shannen
    Did you find this review helpful?
    5 out of 5 stars
    19 February, 2026
    originally posted on Enfamil
    Image

    Perfect for combo feeding

    I bought this the other day to introduce formula with my breast milk and my little one hasn't had any issues as of yet! I love the ready to feed option, saves so much time!
    1 reply from Customer Care team - 1 month ago
    We are thrilled that you are enjoying the convenience of our products. Thanks for such a great review, JNW413! — Tasha, Enfamil Expert
    JNW413
    Did you find this review helpful?
    5 out of 5 stars
    19 February, 2026
    originally posted on Enfamil
    Image

    Love!

    [This review was collected as part of a promotion.] We love this formula and that it is closest to breast milk since we dual feed. It is also the third formula we tried and the one that agreed with our son.
    1 reply from Customer Care team - 1 month ago
    We appreciate your feedback regarding our product, Dani07! Thank you for choosing Enfamil to help give your little guy the best start in life! — Tasha, Enfamil Expert
    Dani07
    Did you find this review helpful?
    5 out of 5 stars
    18 February, 2026
    originally posted on Enfamil
    Image

    Perfect to my new born

    I gave this formula to my new born and this was amazing, he don’t have tummy problems , it was very good for his stomach
    1 reply from Customer Care team - 1 month ago
    What a great review, Idalia! Thanks! — Marcy, Enfamil Expert
    Idalia
    Did you find this review helpful?
    2 out of 5 stars
    13 February, 2026
    originally posted on Enfamil
    Image

    Love the optimum formula

    [This review was collected as part of a promotion.] I bought this a week ago for my baby because it's the closest one to breastmilk it says and sense I breastfeed and do formula feed it has gave me no issues and no worries and I'm happy to see that is fits well into my babies diet because although I can breast feed but sometimes I worry he's not getting enough nutrients and supplements so I combo feed for a little extra support and because also my milk supply isn't that great as others
    1 reply from Customer Care team - 2 months ago
    We always strive to put you and your family first. When you have a minute, please give us a call at 1-800-222-9123 so that we can gather more information. Thank you. — Marcy, Enfamil Expert
    Babyfeedings
    Did you find this review helpful?
    5 out of 5 stars
    12 February, 2026
    originally posted on Enfamil
    Image

    The best

    Love this formula both my babies have been combination fed.
    1 reply from Customer Care team - 2 months ago
    We appreciate you using Enfamil with each of your babies and are happy that you continue to be a part of the Enfamil family! — Tasha, Enfamil Expert
    Vani
    Did you find this review helpful?
    5 out of 5 stars
    11 February, 2026
    originally posted on Enfamil
    Image

    Beyond expectations!

    Was gifted some for our baby shower, and my baby Loved it!! had no issues getting her to try it. Very content with the unexpected hit.
    1 reply from Customer Care team - 2 months ago
    We work hard to bring you the very best products. Thanks for leaving us a review, Alv992! — Tasha, Enfamil Expert
    alv992
    Did you find this review helpful?
    5 out of 5 stars
    9 February, 2026
    originally posted on Enfamil
    Image

    My favorite kind of enfamil

    [This review was collected as part of a promotion.] I love this in powder form after the first month. Its my favorite to use on my baby's
    1 reply from Customer Care team - 2 months ago
    We work hard to bring you the very best products. Thanks for leaving us a review, Hummingbirdmommy2021! — Tasha, Enfamil Expert
    Hummingbirdmommy2021
    Did you find this review helpful?

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