New ArrivalsChristmasHoliday Hosting & EntertainingGift IdeasAI Gift FinderClothing, Shoes & AccessoriesToysElectronicsBeautyGift CardsHomeFurnitureCharacter ShopBabyKitchen & DiningGroceryHousehold EssentialsSchool & Office SuppliesVideo GamesMovies, Music & BooksSports & OutdoorsBackpacks & LuggagePersonal CareHealthPetsUlta Beauty at TargetTarget OpticalParty SuppliesClearanceTarget New Arrivals Target Finds #TargetStyleHanukkahStore EventsAsian-Owned Brands at TargetBlack-Owned or Founded Brands at TargetLatino-Owned Brands at TargetWomen-Owned Brands at TargetLGBTQIA+ ShopTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Enfamil Optimum Enspire Gentlease Powder Infant Formula - 19.5oz - 2 of 4Enfamil Optimum Enspire Gentlease Powder Infant Formula - 19.5oz - 3 of 4Enfamil Optimum Enspire Gentlease Powder Infant Formula - 19.5oz - 4 of 4
Enfamil Optimum Enspire Gentlease Powder Infant Formula - 19.5oz - 1 of 4

Enfamil Optimum Enspire Gentlease Powder Infant Formula - 19.5oz

$51.99 ($2.67/ounce)

In Stock

Eligible for registries and wish lists

Sponsored

About this item

Highlights

  • CONTAINS: 1 - 19.5 oz reusable tub of baby formula milk powder that has Lactoferrin (found in colostrum and breast milk)
  • ENFAMIL: #1 Trusted Infant Formula Brand of Pediatricians and Parents
  • FIRST AND ONLY FORMULA: With lactoferrin, also found in breast milk + colostrum, to support immune health
  • ALL IN ONE COMFORT: Enfamil Enspire Gentlease is scientifically formulated to help ease fussiness, crying, gas and spit-up in 24 hours
  • BRAIN BUILDING AND IMMUNE SUPPORT: DHA has been shown to support brain development and Lactoferrin is a protein found in Colostrum that supports the immune system
  • EASY-TO-DIGEST GENTLE PROTEINS: Designed to be easy for developing digestive systems to digest
  • NON-GMO: Enspire is a non-GMO baby formula that is designed to provide complete nutrition for babies through 12 months
  • #1 TRUSTED BRAND: Enfamil is the #1 Trusted Brand for Brain-building & Immune Support
  • PEDIATRICIAN RECOMMENDED: Enfamil is the #1 infant formula brand recommended by pediatricians
  • SNAP ELIGIBLE: Eligible to be purchased with Supplemental Nutrition Assistance Program (SNAP) benefits

Description

Enfamil Enspire Gentlease Infant Formula is an inspired way to nourish. Enspire Gentlease has MFGM and Lactoferrin, two key components found in breast milk, making it our closest formula ever to breast milk. Lactoferrin is a protein found in colostrum and breast milk that supports the immune system and intestinal development, and MFGM has been shown to support mental development. Enspire is a non-GMO† baby formula that is designed to provide complete nutrition for babies through 12 months. †Not made with genetically modified ingredients, but trace amounts of genetically engineered materials may be present in the product from manufacturing environments and process sources. *QuintilesIMS, using the ProVoice Survey fielded from Janurary 2017 to December 31, 2017.

Serving Size: 5 fl oz

Amount :

Calories: 100
% Daily Value*
Protein 2.3g
Total Fat 5.3g
Total Carbohydrate 10.8g
Water 133g
Omega-6 (linoleic acid LA) 780mg
Vitamin A 300IU
Vitamin D 70IU
Vitamin E 0.2IU
Vitamin K 0.9mcg
Thiamin 80mcg
Riboflavin 140mcg
Vitamin B6 60mcg
Vitamin B12 0.3mcg
Niacin 1000mcg
Folic Acid 16mcg
Pantothenic Acid 500mcg
Biotin 3mcg
Vitamin C 12mg
Choline 24mg
Inositol 24mg
Calcium 82mg
Phosphorus 46mg
Magnesium 8mg
Iron 1.8mg
Zinc 1mg
Manganese 15mcg
Copper 75mcg
Iodine 15mcg
Selenium 2.8mcg
Sodium 40mg
Potassium 108mg
Chloride 63mg
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

corn syrup solids, partially hydrolyzed nonfat milk and whey protein concentrate solids (soy)‡, vegetable oil (contains one or more of the following: palm olein oil, coconut oil, soy oil, high oleic sunflower oil), and less than 2%: lactoferrin, mortierella alpina oil*, schizochytrium sp. oil+, sodium citrate, calcium phosphate, potassium chloride, calcium carbonate, magnesium phosphate, ferrous sulfate, zinc sulfate, cupric sulfate, manganese sulfate, potassium iodide, sodium selenite, soy lecithin, choline chloride, inositol, ascorbic acid, niacinamide, calcium pantothenate, riboflavin, thiamin hydrochloride, vitamin d3, vitamin b6 hydrochloride, folic acid, vitamin k1, biotin, vitamin b12, vitamin e acetate, vitamin a palmitate, taurine, l-carnitine.' '[‡a source of mfgm (milk fat globule membrane composed of proteins and fats) components, *a source of arachidonic acid (ara), +a source of docosahexaenoic acid (dha)]

Allergens & Warnings:

WARNING: Do not use a microwave oven to warm formula. Serious burns may result. Failure to follow these instructions could result in severe harm. Once prepared, infant formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35-40°F (2-4°C) for no longer than 24 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use formula within one hour or discard.
Baby Formula Focus: Easy to Digest, Brain Development, Immune System Support
Base Ingredient: Milk
Form: Powdered
State of Readiness: Mix
Package Quantity: 1
Age Stage: Infant
Net weight: 19.5 Ounces
Beverage container material: Plastic
TCIN: 94051721
UPC: 300875123539
Item Number (DPCI): 007-09-3424
Origin: Made in the USA
Grocery Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers. Any additional pictures are suggested servings only.
If the item details aren’t accurate or complete, we want to know about it.

Shipping details

Estimated ship dimensions: 6.3 inches length x 5.5 inches width x 4.4 inches height
Estimated ship weight: 1.5 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup. If purchased online with SNAP EBT, this item must be returned within 90 days of the date it was shipped, delivered by a Shipt shopper, or made ready for pickup. This 90-day return window is required by SNAP.
See the return policy for complete information.

Q: What is the usual expiration dating to be expected at time of purchase?

submitted by NDB2222 - 1 month ago
  • A: To ensure the highest quality product, the shelf life of our products is reviewed on an ongoing basis. The shelf life for a specific product may vary from batch to batch.  Please refer to the Use By or Expiration date (EXP) printed on each product package to determine the remaining time available for use. Our powder cans have the USE BY date, product abbreviation or name, and batch code embossed into the bottom of our can. If you would like further assistance, feel free to contact us at 1800-222-9123. Karen - Enfamil Expert

    submitted byEnfamil Customer Care - 1 month ago
    Brand expert

Related Categories

Guests are saying

Enfamil Gentlease formula has been a transformative choice for many parents seeking relief for their babies from gas and fussiness. Guests report significant improvements in their infants' comfort, sleep, and overall happiness after switching to this formula. Its easy mixing, pleasant taste, and gentle formulation make it a preferred option for transitioning from breast milk. Many appreciate its nutritional benefits, which closely resemble those of breast milk, ensuring their little ones thrive without tummy troubles.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.8 out of 5 stars with 924 reviews
    easy on tummy: 3.4 out of 5
    easy to prepare: 4.2 out of 5
    quality: 3.6 out of 5
    value: 3.2 out of 5
    60% would recommend
    5 recommendations
    5 out of 5 stars
    27 November, 2025
    originally posted on Enfamil
    Image

    I love gentle ease!

    [This review was collected as part of a promotion.] This formula has helped my baby with gas so much !
    1 reply from Customer Care team - 14 days ago
    Thanks so much for sharing your experience with us, MariN! — Abby, Enfamil Expert
    MariN
    Did you find this review helpful?
    4 out of 5 stars
    27 November, 2025
    originally posted on Enfamil
    Image

    Gentle ease

    Both babies struggled with the formula that was given in the hospital. Our pediatrician recommended gentle ease. Both have responded well with no issues
    1 reply from Customer Care team - 14 days ago
    Thank you for telling us about your experience, T & E. We are grateful for such a wonderful review! — Abby, Enfamil Expert
    T & E
    Did you find this review helpful?
    5 out of 5 stars
    26 November, 2025
    originally posted on Enfamil
    Image

    Great product

    We switched to Enfamil Gentlease because our baby was very gassy and fussy, and it made a noticeable difference. It’s gentler on his stomach, and he seems much more comfortable after feedings. Less crying and less gas overall. This formula has been a lifesaver for us.
    1 reply from Enfamil Customer Care team - 13 days ago
    Hello Fon S! We would love to speak with you directly about your experience with our Enfamil Optimum Gentlease! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7611451. We look forward to speaking with you and seeing how we can help! - Jude, Enfamil Expert
    Fon S
    Did you find this review helpful?
    4 out of 5 stars
    26 November, 2025
    originally posted on Enfamil
    Image

    Sensitive tummy

    [This review was collected as part of a promotion.] We switched to this from the regular neuropro formula and my baby tolerated it much better
    1 reply from Enfamil Customer Care team - 16 days ago
    Hello NateMommy! We would love to speak with you directly about your experience with our Enfamil® Optimum™ (Enspire) Gentlease® Infant! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7595933. We look forward to speaking with you and seeing how we can help! -Lovely, Enfamil Expert
    NateMommy
    Did you find this review helpful?
    3 out of 5 stars
    26 November, 2025
    originally posted on Enfamil
    Image

    Did not help my baby

    [This review was collected as part of a promotion.] Bought one time and Dr gave me some to try but baby did not benefit from what was promoted. At least my baby was having a hard time pooping and passing gas despite following instructions
    1 reply from Enfamil Customer Care team - 16 days ago
    Hi Mari! Thank you for choosing Enfamil Optimum Gentlease! We appreciate your feedback and would like to learn more about your child's experience using our formula. Please give us a call at 1-800-222-9123, choose option 1 and reference #7595605. Thanks! Ava- Enfamil Expert
    Mari
    Did you find this review helpful?
    5 out of 5 stars
    25 November, 2025
    originally posted on Enfamil
    Image

    Baby Loves

    [This review was collected as part of a promotion.] I cannot say enough good things about this baby formula. As a new mom, finding something that’s gentle on my baby’s stomach and helps him feel full and happy has been such a relief. Since switching to this formula, my little one has had zero tummy troubles—no gas, no fussiness, just a content baby who sleeps better and eats consistently.
    1 reply from Customer Care team - 17 days ago
    Thank you for telling us about your experience, Kaylene. We are grateful for such a wonderful review! — Abby, Enfamil Expert
    Kaylene
    Did you find this review helpful?
    3 out of 5 stars
    25 November, 2025
    originally posted on Enfamil
    Image

    My daughter enjoyed it

    [This review was collected as part of a promotion.] It helped with her being gassy and she seemed to enjoy it more than other kinds
    1 reply from Customer Care team - 16 days ago
    Thanks so much for sharing your experience with us, Xoxoenfamil! — Marcy, Enfamil Expert
    Xoxoenfamil
    Did you find this review helpful?
    5 out of 5 stars
    21 November, 2025
    originally posted on Enfamil
    Image

    Preemie/small newborn

    I used this when my baby girl first came home due to her being extra picky and not really eating/finishing her bottles, it honestly made feeding easier and she ate a lot more with less coming back out.
    1 reply from Enfamil Customer Care team - 21 days ago
    Hello! We are happy to hear our Enfamil Optimum (Enspire) Gentlease is working out well for your baby! We appreciate your feedback and would like to learn more about your child’s experience using our formula. Please give us a call at 1-800-222-9123, choose option 1, and reference #7574974. Thanks! Richard - Enfamil Expert
    Tea Sweat
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    20 November, 2025
    originally posted on Enfamil
    Image

    Love this product and company!

    [This review was collected as part of a promotion.] I buy this product every time my baby needs some formula. She loves it absolutely.
    1 reply from Customer Care team - 21 days ago
    We are so happy your little one is loving Enfamil, Nelly. Thank you for taking time to let us know! — Marcy, Enfamil Expert
    Nelly
    Did you find this review helpful?
    5 out of 5 stars
    19 November, 2025
    originally posted on Enfamil
    Image

    Great!

    This formula really helps with my baby's tummy issues.
    1 reply from Enfamil Customer Care team - 23 days ago
    Hi Mama! Thank you for choosing Enfamil® Optimum™ (Enspire) Gentlease®! We appreciate your feedback and would like to learn more about your child's experience using our formula. Please give us a call at 1-800-222-9123, choose option 1 and reference #7562234. Thanks! Baldwin -Enfamil Expert
    Mama
    Did you find this review helpful?
    5 out of 5 stars
    17 November, 2025
    originally posted on Enfamil
    Image

    Love this formula

    [This review was collected as part of a promotion.] This is the best formula we’ve tried and my baby loves it!
    1 reply from Customer Care team - 24 days ago
    We are so happy your little one is loving Enfamil, Grace01. Thank you for taking time to let us know! — Marcy, Enfamil Expert
    Grace01
    Did you find this review helpful?
    5 out of 5 stars
    16 November, 2025
    originally posted on Enfamil
    Image

    They came in clutch after the Byheart Recall

    [This review was collected as part of a promotion.] My baby was on byheart, I breastfeed and supplement so it was really important to find a formula that was similar to breastmilk as possible. After the recall, I felt defeated and didn't know what to try. However, I saw that Enfamil came out with its own formula that was as close to breastmilk as possible. My baby girl loved it immediately, and is doing so well. I wish I would have found this before Byheart. It makes me feel so comforted with the quality and safety standards endamil has with their products, and my baby is doing well / growing well. I will continue to use this formula and love it for my baby
    1 reply from Customer Care team - 25 days ago
    Thank you for telling us about your experience, Linaa. We are grateful for such a wonderful review! — Marcy, Enfamil Expert
    Linaa
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    16 November, 2025
    originally posted on Enfamil
    Image

    Best formula

    For my previous 2 Littles when they were infants, this specific one was our go to formula. Not sure if it was because I did breast and formula but they tummies couldn’t handle the regular yellow label and once we switched over to gentle ease, they stopped spitting/throwing up the formula.
    1 reply from Customer Care team - 25 days ago
    Thanks so much for sharing your experience with us, Dlr2025! — Tasha, Enfamil Expert
    Dlr2025
    Did you find this review helpful?
    5 out of 5 stars
    16 November, 2025
    originally posted on Enfamil
    Image

    Great transition

    I used this for my bandy when we switched from another brand formula and it helped my daughter tummy with the transition.
    1 reply from Customer Care team - 25 days ago
    Thank you for sharing your experience using our product, Alce! We appreciate your feedback! — Marcy, Enfamil Expert
    Alce
    Did you find this review helpful?
    4 out of 5 stars
    15 November, 2025
    originally posted on Enfamil
    Image

    Good stuff

    Has been on it for a few days now. Seems a lot less bloated and gassy after eating.
    1 reply from Enfamil Costumer Care team - 25 days ago
    Hello! We would love to speak with you directly about your experience with our Enfamil Optimum Gentlease! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7549993. We look forward to speaking with you and seeing how we can help! -Hazel, Enfamil Expert
    Howe
    Did you find this review helpful?
    5 out of 5 stars
    13 November, 2025
    originally posted on influenster.com
    Image

    Little one love it

    Honestly i do not see the difference between this and the other enfamil gentlease. Bothe works well for my little one. She has this since she was born and we never have to change to different formula.
    1 reply from Customer Care team - 28 days ago
    Thank you for telling us about your experience, lhb2_528. We are grateful for such a wonderful review! — Marcy, Enfamil Expert
    lhb2_528
    Did you find this review helpful?
    5 out of 5 stars
    13 November, 2025
    originally posted on Enfamil
    Image

    Best Formula!

    I bought this for my almost 7 week old baby boy because I will be going back to work soon and am struggling to pump between his feeds. He has not had any issues with the transition of having the formula and breastmilk. He is sleeping better and less fussy.
    1 reply from Enfamil Costumer Care team - 28 days ago
    Hello Josh! We would love to speak with you directly about your experience with our Enfamil® Optimum™ Gentlease®! One of our team members will be reaching out to you via email, but if you would like to speak with us immediately, please give us a call at 1-800-222-9123, select option 1 and reference #7535265. We look forward to speaking with you and seeing how we can help! -Hazel, Enfamil Expert
    Josh
    Did you find this review helpful?
    5 out of 5 stars
    13 November, 2025
    originally posted on Enfamil
    Image

    Love this product!

    [This review was collected as part of a promotion.] I switched from similac to this brand and absolutely love it! My baby stomach problems went away within the first week!
    1 reply from Customer Care team - 29 days ago
    We at Enfamil are so glad you're a part of our family, Lee Lee! Thanks for taking time to leave a review! — Abby, Enfamil Expert
    Lee Lee
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    12 November, 2025

    Baby hates the taste!

    By baby is exclusively breastfed and I was looking to supplement with formula. My baby hates the taste and refuses to drink even an ounce of it.
    1 reply from Enfamil Team team - 29 days ago
    Hi Evelyn! We’re sorry to hear your little one’s experience on our Enfamil® Enspire™ Gentlease®. We appreciate your feedback and would like to get a little more information about your baby’s experience on our formula. Please give us a call at 1-800-222-9123, choose option 1, and reference #7532359. Thanks! Andrea -Enfamil Expert
    Evelyn
    easy on tummy: 1 out of 5
    easy to prepare: 5 out of 5
    quality: 3 out of 5
    value: 1 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    9 November, 2025
    originally posted on Enfamil
    Image

    Amazing nutrients

    [This review was collected as part of a promotion.] I buy this product every time my baby needs formula. I can never switch to a different brand.
    1 reply from Customer Care team - 1 month ago
    We have the best customers and we thank you for being one of them, Jenelle. We appreciate you taking the time to leave us a review! — Abby, Enfamil Expert
    Jenelle
    Did you find this review helpful?

    Get top deals, latest trends, and more.

    Privacy policy

    Footer

    About Us

    About TargetCareersNews & BlogTarget BrandsBullseye ShopSustainability & GovernancePress CenterAdvertise with UsInvestorsAffiliates & PartnersSuppliersTargetPlus

    Help

    Target HelpReturnsTrack OrdersRecallsContact UsFeedbackAccessibilitySecurity & FraudTeam Member ServicesLegal & Privacy

    Stores

    Find a StoreClinicPharmacyTarget OpticalMore In-Store Services

    Services

    Target Circle™Target Circle™ CardTarget Circle 360™Target AppRegistrySame Day DeliveryOrder PickupDrive UpFree 2-Day ShippingShipping & DeliveryMore Services
    PinterestFacebookInstagramXYoutubeTiktokTermsCA Supply ChainPrivacy PolicyCA Privacy RightsYour Privacy ChoicesInterest Based AdsHealth Privacy Policy