EasterBlack-owned or founded brands at TargetGroceryClothing, Shoes & AccessoriesBabyHomeFurnitureKitchen & DiningOutdoor Living & GardenToysElectronicsVideo GamesMovies, Music & BooksSports & OutdoorsBeautyPersonal CareHealthPetsHousehold EssentialsArts, Crafts & SewingSchool & Office SuppliesParty SuppliesLuggageGift IdeasGift CardsClearanceTarget New ArrivalsTarget Finds#TargetStyleTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores

Sponsored

Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™

Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™ - image 1 of 4
Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™ - image 2 of 4
Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™ - image 3 of 4
Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™ - image 4 of 4
Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™ - image 1 of 4
$6.79 when purchased online
Target Online store #3991

About this item

Highlights

  • Packaging may vary. Same trusted quality
  • Pain reliever caplets contain acetaminophen, aspirin and caffeine
  • Helps to relieve headache and migraine pain, as well as muscle aches and other pain
  • Compare to the active ingredients in Excedrin Extra Strength

Description

Go through your day with relief from headaches and other pains with the help of the Acetaminophen and Aspirin Added-Strength Pain Reliever Caplets from up&up™. With a combination of acetaminophen, aspirin and caffeine, you'll find quick relief from throbbing headaches or migraines. With each pain relief caplet, you can relieve the pain caused by muscle aches and menstrual cramps as well headache pain. The added caffeine helps to relax muscle contractions and improve mental altertness as you head off to work or spend time with loved ones.


We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Suggested Age: 12 Years and Up
Health Facts: Contains Acetaminophen, Contains Aspirin, Contains Caffeine
Product Warning: Consult a doctor if you have heart disease, Contains Acetaminophen, do not use if you have a bleeding problem, not for children under the age of 12, consult a doctor if you have high blood pressure, do not use if you have kidney disease, Contains Caffeine, do not use if you are pregnant
Active Ingredient Strength Value: 250 Milligrams
Product Form: Caplet
Primary Active Ingredient: Acetaminophen
Package Quantity: 275
TCIN: 11004687
UPC: 349483370720
Item Number (DPCI): 094-01-0124
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details above aren’t accurate or complete, we want to know about it.

Ingredients:

active ingredients: in each tablet: acetaminophen (250 mg), aspirin (250 mg) (nsaid), caffeine (65 mg). purpose: pain reliever; pain reliever, nonsteroidal anti-inflammatory drug; pain reliever aid. inactive ingredients: corn starch, crospovidone, hypromellose, microcrystalline cellulose, povidone, propylene glycol, sodium lauryl sulfate, sodium starch glycolate, stearic acid, titanium dioxide.

Shipping details

Estimated ship dimensions: 5.4331 inches length x 3.7795 inches width x 2.6772 inches height
Estimated ship weight: 0.5291 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Summary of reviews

Guests find this headache relief medication to be an effective and affordable alternative to name brands like Excedrin. It works well for migraines, toothaches, and general pain relief. However, some guests have reported issues with the taste and smell of the pills, as well as occasional stomach discomfort.
  • Thumbs up graphic, effective
  • Thumbs up graphic, affordable
  • Thumbs up graphic, same ingredients
  • Thumbs up graphic, fast-acting
  • Thumbs up graphic, versatile
  • Thumbs down graphic, bad taste
  • Thumbs down graphic, stomach discomfort
  • Thumbs down graphic, chlorine smell
Generated by AI from the text of guest reviews (includes incentivized reviews)
4.7 out of 5 stars with 1220 reviews
value: 4.65 out of 5
quality: 4.4 out of 5
83% would recommend
125 recommendations

Great bargrain alternative

5 out of 5 stars
Thumbs up graphic, would recommend
Karen T - 1 month ago, Verified purchaser
Works just as well as the name brand.
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

Migraine Relief

5 out of 5 stars
Thumbs up graphic, would recommend
Bee - 2 months ago, Verified purchaser
I suffer from chronic migraines and this always knocks my migraine out within 30 minutes and is a fraction of the price of the name brand competitors. I have one on my desk, my car, home and my purse.
quality: 5 out of 5
value: 5 out of 5
3 guests found this review helpful. Did you?

instant relief!

5 out of 5 stars
Thumbs up graphic, would recommend
Rre23 - 2 months ago
Affordable and work very fast. My migraine had me feeling like I was gonna vomit and pass out. I took a dose at 7:30 pm and was able to eat my dinner and put my kids to bed by 8pm. Headache still lingered for about an hour but my right eye didn’t feel like it was going to pop out of my head.
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

DO NOT reccomend !

1 out of 5 stars
Thumbs down graphic, would not recommend
anonymous - 2 months ago, Verified purchaser
Bought these as an alternative vs name brand however, I gave this to my mom to elevate her headache and she had sharp stomach pains in her abdomen and experienced a bad reaction. Caused an emergency room visit.
value: 1 out of 5
quality: 1 out of 5
Did you find this review helpful?

Perfect excedrin dupe!

5 out of 5 stars
Thumbs up graphic, would recommend
Katie - 3 months ago, Verified purchaser
Just like Excedrin for a tenth of the price! Thank goodness, such a money saver!
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

Migraine miracle

5 out of 5 stars
Thumbs up graphic, would recommend
Noahs Mom - 3 months ago, Verified purchaser
These are the only thing that treats my migraines. They work fast and are such a great price !
value: 5 out of 5
quality: 5 out of 5
Did you find this review helpful?

Awesome

5 out of 5 stars
Thumbs up graphic, would recommend
A - 4 months ago, Verified purchaser
I bought these when I last ran out of excedrin and they work miracles. Works just as great for my migraines.
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

I recommend

5 out of 5 stars
Thumbs up graphic, would recommend
FlaMich - 4 months ago, Verified purchaser
Works fast and last thru my 8hr day. One pill takes care of my toothache.
Did you find this review helpful?

Great value

5 out of 5 stars
Thumbs up graphic, would recommend
Mbuz - 4 months ago, Verified purchaser
I tend to get a lot of headaches, and these definitely do the trick! Much less expensive than Execedrin, with the same ingredients.
value: 5 out of 5
quality: 5 out of 5
Did you find this review helpful?

Migraine relief

5 out of 5 stars
Thumbs up graphic, would recommend
Toyreview12 - 5 months ago, Verified purchaser
I get migraines often. This is my go to medicine to relieve them.
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

Nsaid

5 out of 5 stars
Thumbs up graphic, would recommend
Lisa - 5 months ago, Verified purchaser
Gets the job done with the store brand. nsaid is still nsaid Jsut without the fancy well known name but cheaper.
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

Get these

5 out of 5 stars
Thumbs up graphic, would recommend
Great soap - 5 months ago, Verified purchaser
These have absolutely saved me and you can’t beat the price!
value: 5 out of 5
quality: 5 out of 5
Did you find this review helpful?

It works

5 out of 5 stars
Thumbs up graphic, would recommend
Amk - 5 months ago, Verified purchaser
This works just as good as the name brand, for a fraction of the cost. Good to have on hand for headaches that Tylenol just won't touch.
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?

Just get acetaminophen

2 out of 5 stars
Thumbs down graphic, would not recommend
Benice - 6 months ago, Verified purchaser
The caffeine is counterproductive. It would just give me a worse headache
Did you find this review helpful?

Good

5 out of 5 stars
Thumbs up graphic, would recommend
Mrs R - 6 months ago, Verified purchaser
I buy this in lieu of the name brand one. It works just as well and much cheaper.
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

Super helpful! Day saved

5 out of 5 stars
Thumbs up graphic, would recommend
Jadyb - 6 months ago
best OTC headache relief, loved the price too 👍🏽
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?

Grear Product

5 out of 5 stars
Thumbs up graphic, would recommend
TyIda - 6 months ago, Verified purchaser
This 100% works as well as excedrin
1 guest found this review helpful. Did you?

Pass On This Generic

1 out of 5 stars
Thumbs down graphic, would not recommend
TC - 6 months ago, Verified purchaser
Migraine sufferer for decades and typically use Excerdrin. Picked up Up & Up headache relief because of cost but states same ingredients. Headache returned within 4 hours (not uncommon if I am having a bad day) but every time I took it. I experienced extreme sharp stomach pains within hour of each use. I thought it was another item I was taking but once removed, it was clear this headache reliever was tearing my stomach up. I did not read reviews until after I isolated the product. Did not smell or taste bad. I took one dose of Excedrin, headache and stomach ache gone. Price is right but pass on this generic headache relief. You will only add to the pain.
quality: 1 out of 5
value: 1 out of 5
1 guest found this review helpful. Did you?

Same as Excedrin but for the fraction of a cost

5 out of 5 stars
Thumbs up graphic, would recommend
Joshua - 7 months ago, Verified purchaser
Love the price and it has the same ingredients as excedrin
Did you find this review helpful?

Repeat purchase

5 out of 5 stars
Thumbs up graphic, would recommend
D3lewis8 - 7 months ago, Verified purchaser
Works just like the name brands
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?

Get top deals, latest trends, and more.

Privacy policy

Footer

About Us

About TargetCareersNews & BlogTarget BrandsBullseye ShopSustainability & GovernancePress CenterAdvertise with UsInvestorsAffiliates & PartnersSuppliersTargetPlus

Help

Target HelpReturnsTrack OrdersRecallsContact UsFeedbackAccessibilitySecurity & FraudTeam Member Services

Stores

Find a StoreClinicPharmacyOpticalMore In-Store Services

Services

Target Circle™Target Circle™ CardTarget Circle 360™Target AppRegistrySame Day DeliveryOrder PickupDrive UpFree 2-Day ShippingShipping & DeliveryMore Services
PinterestFacebookInstagramXYoutubeTiktokTermsCA Supply ChainPrivacyCA Privacy RightsYour Privacy ChoicesInterest Based AdsHealth Privacy Policy