New ArrivalsHalloweenChristmasGift IdeasClothing, Shoes & AccessoriesHomeFurnitureElectronicsToysVideo GamesGroceryHousehold EssentialsBeautyBabyKitchen & DiningSchool & Office SuppliesMovies, Music & BooksCharacter ShopSports & OutdoorsBackpacks & LuggagePersonal CareHealthPetsUlta Beauty at TargetTarget OpticalParty SuppliesGift CardsBullseye’s PlaygroundDealsClearanceTarget New Arrivals Target Finds #TargetStyleCelebrate DiwaliDía de MuertosStore EventsAsian-Owned Brands at TargetBlack Beyond MeasureMás QueWomen-Owned Brands at TargetLGBTQIA+ ShopTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Arthritis Diclofenac Sodium (NSAID) Pain Reliever Gel - up&up™ - 2 of 4Arthritis Diclofenac Sodium (NSAID) Pain Reliever Gel - up&up™ - 3 of 4Arthritis Diclofenac Sodium (NSAID) Pain Reliever Gel - up&up™ - 4 of 4
Arthritis Diclofenac Sodium (NSAID) Pain Reliever Gel - up&up™ - 1 of 4

Arthritis Diclofenac Sodium (NSAID) Pain Reliever Gel - up&up™

$17.79

Size5.29oz

In Stock

Eligible for registries and wish lists

At a glance

Sponsored

About this item

Highlights

  • Compare to the active ingredient of Voltaren Arthritis Pain.
  • Arthritis pain relief for hand, wrist, elbow, foot, ankle, knee.
  • Significant pain relief within 7 days, used 4 times daily.
  • Non-steroidal anti-inflammatory drug relieves arthritis and joint pain.
  • Same strength and formula as original prescription strength.

Description

Compare to the active ingredient in Voltaren Arthritis Pain. Life doesn't stop for arthritis pain. Get moving with Up&Up Arthritis Pain Relieving Gel, with diclofenac sodium 1 Percent, a non-steroidal anti-inflammatory drug (NSAID), in original prescription strength. A topical arthritis pain reliever, this medicated gel penetrates skin at the application site for significant relief within 7 days with 4 times-per-day use. Apply to hand, wrist, elbow, foot, ankle or knee for daily treatment of arthritis pain. Clinically proven to relieve arthritis pain. Up&Up Arthritis Pain Relieving Gel reduces joint pain and inflammation so you can keep going strong.
Suggested Age: 18 Years and Up
Product Warning: Consult a doctor if you are pregnant or nursing, consult a doctor if you have a fever, skin irritant, do not use if you have a bleeding problem, consult a doctor if you have heart disease, consult a doctor if taking prescription drugs, consult a doctor if you have kidney disease, consult a doctor if you have a breathing problem, keep out of reach of children, consult a doctor if you have stomach problems
Product Form: Cream
Primary Active Ingredient: Diclofenac Sodium
Package Quantity: 1
Net weight: 5.29 Ounces
Battery: No Battery Used
TCIN: 81063093
UPC: 370030117789
Item Number (DPCI): 094-01-0153
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Ingredients:

carbomer homopolymer type c, cocoyl caprylocaprate fragrance, isopropyl alcohol, mineral oil, polyoxyl 20 cetostearyl ether, propylene glycol, purified water, strong ammonia solution' '

Allergens & Warnings:

Tamper evident statement: Do not use If safety seal on tube nozzle is broken or missing., For external use only, Warnings For external use only Allergy alert Diclofenac may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may Include: hives, asthma (wheezing), skin reddening, blisters, facial swelling, shock, rash, If an allergic reaction occurs, stop use and seek medical help right away. Liver warning This product contains diclofenac. Liver damage may occur if you apply more or for a longer time than directed, when using other drugs containing diclofenac Stomach bleeding warning This product contains an NSAID, which may cause severe stomach bleeding. The chance is small but higher if you are age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinning (anticoagulant) or steroidi drug, take other drugs containing prescription or nonprescription NSAIDs (aspirin, Ibuprofen, naproxen, or others), have 3 or more alcoholic drinks every day while using this product, m apply more or for longer than directed, Heart attack and stroke warning: NSAIDs, except aspirin, Increase the risk of heart attack, heart fallure, and stroke. These can be fatal. The risk is higher if you use more than directed or for longer than directed. Do not use m if you have ever had an allergic reaction to any other pain reliever or to a fever reducer, for strains, sprains, bruises or sports injuries. This product has not been shown to work for these types of injuries. right before or after heart surgery

Shipping details

Estimated ship dimensions: 2.32 inches length x 2.58 inches width x 6.83 inches height
Estimated ship weight: 0.43 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Related Categories

Guests are saying

The arthritis pain reliever gel is praised for its effectiveness in alleviating joint pain, comparable to name-brand products but at a more affordable price. Guests appreciate its fast-acting relief, non-greasy texture, and ease of use. However, many have noted a strong, unpleasant fragrance that can be off-putting. Despite this, the product remains a popular choice for managing arthritis pain.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.5 out of 5 stars with 632 reviews
    quality: 3.54 out of 5
    value: 3.87 out of 5
    60% would recommend
    46 recommendations
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    5 September, 2025Verified purchase

    Gross

    I tried this as a replacement for lidocaine patches and, while also seemingly providing no comparative relief, it was so sticky even after allowing time to dry before dressing that my loose pants were attached to my knee all day. Even after pulling them away from the injury, it kept sticking again. I had to literally wash my leg in the middle of my work day with little help because of how much it seeped into the clothes.
    1 reply from the Product Manufacturer team - 1 month ago
    We are sorry to hear about your experience with the Up & Up Pain Reliever Gel. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2080780. We look forward to addressing your concerns and hearing from you!
    JJ
    quality: 1 out of 5
    value: 1 out of 5
    Did you find this review helpful?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    30 August, 2025Verified purchase

    Not so good as the name brand

    Mom uses with a neck brace for therapy. She says it doesn't work as well as the name brand (Voltarin).
    1 reply from the Product Manufacturer team - 2 months ago
    We are sorry to hear that the Pain Reliever Gel did not work well. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2079080. We look forward to addressing your concerns and hearing from you!
    MsT
    quality: 3 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    2 out of 5 stars
    24 August, 2025Verified purchase

    Disappointing

    My doctor recommended Voltaren for pain in my shoulder. I have usually been very happy with Target brands, but in this case, this was a disappointment. It was very runny and didn’t seem to bring much relief.
    1 reply from the Product Manufacturer team - 2 months ago
    We are sorry to hear about your experience with the Arthritis Diclofenac Sodium (NSAID) Pain Reliever Gel product. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 1-800-719-9260 or via email by going to www.perrigo.com/contact-us and reference case number 2076367. We look forward to addressing your concerns and hearing from you!
    SW
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    16 November, 2024Verified purchase

    Great pain relief, and cheaper

    Works just as well as the brand medication for a much better price.
    Jessica
    quality: 5 out of 5
    value: 5 out of 5
    7 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    6 November, 2024Verified purchase

    Target brand

    This works just like the brand name and its much cheaper. Keep up the good work Target.
    Dimples
    7 guests found this review helpful. Did you?
    2 out of 5 stars
    Thumbs down graphic, would not recommend
    20 September, 2024Verified purchase

    Don't think it really does anything

    I honestly don’t think that this does too much. I wish that it was a roll-on as well because with it being a squeeze tube, it definitely gets messy and all over your fingers.
    Chanellezee
    quality: 2 out of 5
    value: 4 out of 5
    6 guests found this review helpful. Did you?
    2 out of 5 stars
    Thumbs down graphic, would not recommend
    10 May, 2024Verified purchase

    Weirdly stinky

    It probably works, considering it has the same active ingredient as the brand name. But it smells terrible, like cheap cologne worn by old men. Lingers after I was my hands. The brand name and other store brands don't have this odor. I bought this thinking I was getting a deal - now I know why it's so cheap. And they only sell huge tubes. Shop elsewhere or buy the brand name.
    Cologne Hands
    11 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    22 January, 2024Verified purchase

    (NSAID) pain reliever

    It works fast and easy to use.
    glennm916
    value: 5 out of 5
    quality: 5 out of 5
    6 guests found this review helpful. Did you?
    2 out of 5 stars
    12 December, 2023Verified purchase

    Smelly

    This has a disgusting floral fragrance. I returned it. If it was unscented I would use it.
    Liz
    11 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    8 October, 2023Verified purchase

    Great for arthritus

    Works well. Just like name brand, more affordabe!
    lynnewinne
    5 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    12 September, 2023Verified purchase

    Fail, garbage

    Not a single difference
    Cyn
    quality: 1 out of 5
    value: 1 out of 5
    2 guests found this review helpful. Did you?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    7 August, 2023Verified purchase

    Stinky

    Effective but stinky like cheap perfume! Apparently the name brand does not have the same problem….I’ll spend the extra $$ next time
    Kdaw
    value: 3 out of 5
    quality: 3 out of 5
    3 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    10 June, 2023Verified purchase

    OTC and ready for your knee!

    I used to only be able to get this via the pharmacy. It’s so nice to have it OTC. It works well for the bursitis in my hip.
    JessUrbs
    value: 5 out of 5
    quality: 5 out of 5
    11 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    27 April, 2023Verified purchase

    Great Arthritis Pain Releiver

    This gel.ua wonderful for arthritis pain! Not greasy and only sticky until dried. Really helped after rotator cuff surgery.
    Lou
    6 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    15 April, 2023Verified purchase

    Works well for me and costs $$ less than brand name

    I liked the smell- a hint of alcohol- not like others with strong menthol scents. I used this on my knee while while I was Waiting for my surgery to be scheduled and it helped. I also use it on my neck/shoulders after sitting at a computer all day at work .
    LuvN that Makeup
    quality: 5 out of 5
    value: 5 out of 5
    6 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    9 April, 2023Verified purchase

    Miracle for joint pain

    My doctor wanted to prescribe this for me years ago because I couldn't handle side effects from the Diclofenac oral, but he said it was cost prohibitive. So glad you can now buy this for a reasonable price OTC. Works like nothing else on joint pain. Target brand has a scent I don't like but it goes away quickly.
    LOB
    9 guests found this review helpful. Did you?
    5 out of 5 stars
    16 March, 2023Verified purchase

    Use daily for osteoarthritis

    I have osteoarthritis in both hands, thanks to decades of working on a computer for 8+ hours a day. I use this daily and it really helps! Just as good as the prescription I used to pay hundreds of dollars for, and just as good as the name brand OTC now.
    mpayne
    12 guests found this review helpful. Did you?
    5 out of 5 stars
    18 December, 2022Verified purchase

    Good pain reliver.

    Gets rid of arthritis pain for a while.
    bewalt330
    6 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    15 December, 2022Verified purchase

    Floral very strong smell

    Unpleasant smell. It works but only if you can put up with the smell
    JenRo
    quality: 1 out of 5
    value: 1 out of 5
    8 guests found this review helpful. Did you?
    5 out of 5 stars
    22 November, 2022Verified purchase

    Great generic option

    This works equally well to the name brand version of the same product. Why pay more?
    Nope
    7 guests found this review helpful. Did you?

    Get top deals, latest trends, and more.

    Privacy policy

    Footer

    About Us

    About TargetCareersNews & BlogTarget BrandsBullseye ShopSustainability & GovernancePress CenterAdvertise with UsInvestorsAffiliates & PartnersSuppliersTargetPlus

    Help

    Target HelpReturnsTrack OrdersRecallsContact UsFeedbackAccessibilitySecurity & FraudTeam Member ServicesLegal & Privacy

    Stores

    Find a StoreClinicPharmacyTarget OpticalMore In-Store Services

    Services

    Target Circle™Target Circle™ CardTarget Circle 360™Target AppRegistrySame Day DeliveryOrder PickupDrive UpFree 2-Day ShippingShipping & DeliveryMore Services
    PinterestFacebookInstagramXYoutubeTiktokTermsCA Supply ChainPrivacy PolicyCA Privacy RightsYour Privacy ChoicesInterest Based AdsHealth Privacy Policy