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Tylenol 8 Hour Arthritis Pain Reliever Extended-Release Caplets - Acetaminophen
$12.99 ($0.13/count)
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About this item
Highlights
- Temporarily relieves minor arthritis pain as well as other aches and pains
- 650 milligrams of acetaminophen per caplet
- Fast-acting relief lasts up to eight hours
- Bi-layer caplet design
Description
TYLENOL 8 HR Arthritis Pain Extended Release Caplets temporarily relieves the minor pain of arthritis. With 650 milligrams of acetaminophen per caplet, this pain medicine also temporarily relieves aches and pains associated with muscular aches, backache, premenstrual and menstrual cramps, the common cold, headache, and toothache. From TYLENOL, the #1 doctor-recommended brand of pain relievers, these caplets also temporarily reduce fever. The bi-layer design delivers fast-acting relief that lasts up to eight hours.
Suggested Age: 18 Years and Up
Health Facts: Contains Acetaminophen
Active Ingredient Strength Value: 650 Milligrams
Product Warning: Contains Acetaminophen
Product Form: Caplet
Primary Active Ingredient: Acetaminophen
Package Quantity: 100
Net weight: .27 Pounds
TCIN: 47944784
UPC: 300450838216
Item Number (DPCI): 094-01-0943
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
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Active ingredients
acetaminophen' '650.0mg
Purpose
Pain reliever/fever reducerUses
■ temporarily relieves minor aches and pains due to: ■ minor pain of arthritis ■ muscular aches ■ backache ■ premenstrual and menstrual cramps ■ the common cold ■ headache ■ toothache ■ temporarily reduces feverDirections
Directions ■ do not take more than directed (see overdose warning) Adults ■ take 2 caplets every 8 hours with water ■ swallow whole; do not crush, chew, split or dissolve ■ do not take more than 6 caplets in 24 hours ■ do not use for more than 10 days unless directed by a doctor Under 18 years of age ■ ask a doctorOther information
NDC 50850-783-32Inactive ingredients
inactive ingredients: carnauba wax, hydroxyethyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, modified starch, povidone, powdered cellulose, pregelatinized starch, sodium starch glycolate, titanium dioxide, triacetin' '
Shipping details
Estimated ship dimensions: 2.17 inches length x 2.52 inches width x 4.19 inches height
Estimated ship weight: 0.25 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.
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Guests are saying
This product is highly regarded for its effectiveness in relieving arthritis pain, providing up to 8 hours of relief. Many guests appreciate its fast-acting formula and the absence of significant side effects. The compact packaging makes it convenient for on-the-go use, and it is trusted by many for managing chronic pain. However, some guests have raised concerns about the difficulty in opening the bottle, which can be challenging for those with arthritis.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.7 out of 5 stars with 1117 reviews
quality: 4.73 out of 5
value: 4.52 out of 5
100% would recommend
40 recommendations
4 out of 5 stars
14 November, 2025
originally posted on influenster.com

Helps with joint pain
These really seem to help with aching joints. I have tried other OTC for arthritis pain and this seems to work for me the best. Packaging is fine with no problems.
4 out of 5 stars
30 September, 2025
originally posted on influenster.com

Good pain relief
This really helps manage my joint pain throughout the day. I don’t have to keep reaching for more pills every few hours, which is a big relief. It’s gentle on my stomach compared to some other pain meds and kicks in fairly quickly. The caplets are a bit large, but manageable with water. Overall, it’s reliable, effective, and makes daily aches a lot easier to handle.
4 out of 5 stars
6 September, 2025
originally posted on tylenol.com
(no review title)
Why do you not show safe dosage on label ie: how many pills can be safely taken per 24 hrs.
5 out of 5 stars
24 August, 2025
originally posted on influenster.com

Over the counter relief
This is a great over the counter medicine to help ease the pain in your joints and arthritis. It comes in a box with a bottle inside. When you take 2 tablets it helps relieve your pain up to 8 hrs.
5 out of 5 stars
12 August, 2025
originally posted on influenster.com

Good items
Show a person taking TYLENOL® 8 HR Arthritis Pain in the morning with sunrise in the background. Capture a person peacefully sleeping with a bottle of TYLENOL® 8 HR Arthritis Pain on the nightstand.
4 out of 5 stars
1 June, 2025
originally posted on influenster.com

Helps
I'm an artist and I use my hands a lot to create knitted, woven, sculpted, painted, and/or drawn items. Though I do not have arthritis, thankfully, my hands still ache sometimes. This helps on those days.
5 out of 5 stars
18 April, 2025
originally posted on tylenol.com
Easy to swallow and no side effects.
[This review was collected as part of a promotion.] This Tylenol is the best yet reduces pain very fast with no side effects I give give it a ten.
5 out of 5 stars
Thumbs up graphic, would recommend
23 March, 2025Verified purchase
Lifesaver
I am allergic to aspirin, NSAIDs and codeine. The 8 hour Tylenol Arthritis works for me amazingly. Also, this was the only thing I could take when I had a fractured sacrum. This and a heating pad saved me.
4 out of 5 stars
14 March, 2025
originally posted on tylenol.com
Great product
I thought this about a month ago and it does kind of work
2 out of 5 stars
11 March, 2025
originally posted on tylenol.com
Not as Good as I thought it would be
I bought this product recently for arthritis pain in knees. It did seem to be helping with my pain. However, I began to experience redness and itching over my entire face and eye lids. I had an appointment with my doctor for my annual physical already scheduled. She told me to stop taking Tylenol 8 HR Arthritis immediately. As soon as I stopped taking the Tylenol, the skin irritation cleared up. I've never had a reaction to regular Tylenol or anything else before. Use with caution.
5 out of 5 stars
25 February, 2025
originally posted on influenster.com

Excellent for arthritis pain. 🦴💊
The packaging is small and easy to carry, affordable price, it is very effective because it soothes the pain for a while, the effect lasts a long time, and its ingredients are good.
5 out of 5 stars
22 January, 2025
originally posted on tylenol.com
Great product
It’s great! It works so well on my arthritis in my neck and back!
3 out of 5 stars
19 November, 2024
originally posted on tylenol.com
Bottle is hard to open for arthritis sufferers
The medicine works fine, but why is an arthritis medication in a hard to open bottle!?! Please do better!
1 reply from Consumer Care Center team - 1 year ago
Thank you so much for bringing this to our attention! We appreciate your review and would like to learn more about your experience. When you have a moment, please give us a call at 1-877-489-5366. Our team is available Monday-Friday, 9:00 am-5:30 pm EST. We hope to hear from you soon!
5 out of 5 stars
11 November, 2024
originally posted on tylenol.com
(no review title)
I have only been taking this for 2 days but I am already feeling better. Still have some pain but not as severe. I will continue to use this pain medication until it no longer works. Hopefully it will continue to work for a long time.
5 out of 5 stars
10 August, 2024
originally posted on tylenol.com
this is a great pain now for arthritis
I’m hospice nurse and I find my older patients seem to have arthritis almost universally. I have never found Tylenol arthritis to not help. It’s wonderful.
3 out of 5 stars
5 August, 2024
originally posted on tylenol.com
Mixed feelings on my first and only use
With a Hurricane in the area or on blustery rainy days the joints in my hands & feet throb, with pain, due to the weather pressure. I took 2 caplets & it didn’t help the throbbing pain until 4 hours later but I was thankful it was finally working. The pain didn’t completely go away but it was lots less & the throbbing had stopped, which was a huge relief. I do have to say that after the 4 hours I did feel nauseated, a bit achey in my tummy, some lightheadedness & not quite right. I don’t think the pain relief is quite worth the side effects, for me. I was hopeful but I won’t be using it again.
5 out of 5 stars
25 July, 2024
originally posted on tylenol.com
Give it Try
It definitely worked as a game-changing hip arthritis treatment for me. Look it depends on the person and the etiology of your chronic health issues, as well as what you're currently doing about those issues as far as medications you're taking and health/nutrition protocols your on. For me, my condition has improved steadily with faith, cleansing, juicing and, food eliminations. That's a long process, but God ( in the universal sense) helped me stick to it and after a loooong time, it all began to pay off. In a sense, I feel I healed my body to an extent that the meds, including otc pharmaceuticals like Tylenol Arthritis, can work better than they did at a more dire point in my chronic conditions in the past. Time and faith go hand-in-hand with the body getting healed enough to truly benefit from the help of targeted pharmaceuticals like Tylenol Arthritis. So give it try, but know if it's not quite right now, pray about it and be patient as YOU grow to understand how it all works together for your good.
1 out of 5 stars
10 July, 2024
originally posted on tylenol.com
Too hard for me to open the bottle!
I am really concerned that a person with arthritis buys the product and then can't even open it to use... why can't I push down the lid to open the bottle? Crazy.... that is cruel.
1 reply from Consumer Care Center team - 1 year ago
Thank you so much for bringing this to our attention! We appreciate your review and would like to learn more about your experience. When you have a moment, please give us a call at 1-877-489-5366. Our team is available Monday-Friday, 9:00 am-5:30 pm EST. We hope to hear from you soon!
5 out of 5 stars
28 June, 2024
originally posted on tylenol.com
Dr. Recommended it
I depend on it as the pain subsides and gradually goes away so that I can get to sleep
5 out of 5 stars
20 June, 2024
originally posted on tylenol.com
I start to feel relief in 15 minutes!
I am so pleased with this for knee arthritis. Goes to work fast and keeps me covered every 8 hours. Noticeable difference without it. My 3 friends now take it and they are glad I shared info with them. I am 67.