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Avene Cicalfate+ Intensive Skin Restorative Face Serum: Paraben-Free, Deep Hydration, Unscented, 13.2 Net Weight - 2 of 4Avene Cicalfate+ Intensive Skin Restorative Face Serum: Paraben-Free, Deep Hydration, Unscented, 13.2 Net Weight - 3 of 4Avene Cicalfate+ Intensive Skin Restorative Face Serum: Paraben-Free, Deep Hydration, Unscented, 13.2 Net Weight - 4 of 4
Avene Cicalfate+ Intensive Skin Restorative Face Serum: Paraben-Free, Deep Hydration, Unscented, 13.2 Net Weight - 1 of 4

Avene Cicalfate+ Intensive Skin Restorative Face Serum: Paraben-Free, Deep Hydration, Unscented, 13.2 Net Weight

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At a glance

About this item

Highlights

  • Avène Cicalfate+ Intensive Restorative Serum is an innovative, barrier-strengthening formula that helps restore the skin’s natural barrier while protecting against daily external aggressors.
  • Suitable for all skin types including even the most sensitive skin.
  • A versatile serum with a lightweight texture that easily integrates into any skincare routine.
  • Immediately and durably soothes feelings of tightness and discomfort associated with dryness*.
  • Fragrance-free, paraben-free, sulfate-free, alcohol-free, silicone-free, mineral oil-free, ethoxylated agent-free, and silica-free.
  • Pair with Avène Cicalfate+ Restorative Protective Cream for a complete skin barrier routine.
  • 96% Ingredients of natural origin
  • *Footnote: Auto-evaluation immediately after application; 35 subjects; based on Sensitive scale, D1, D43.

Description

Avène Cicalfate+ Intensive Restorative Serum is a lightweight, fast-absorbing serum powered by two dermatologist-grade ingredients—TRP-Regulin™, clinically proven to reduce skin sensitivity and soothe discomfort, and Pro-Vitamin B5, known to strengthen and deeply hydrate the skin barrier. This advanced formula helps restore and fortify the skin’s natural defenses against daily external aggressors. Clinically proven to help restore the skin barrier in one day*. *Footnote: Pharmacological test on RHE under hydric stress.

Powered by Key Ingredients:
TRP-Regulin™: Helps reduce skin sensitivity and soothes sensations of discomfort.
Pro-Vitamin B5: Effectively strengthens and hydrates the skin barrier.
Avène Thermal Spring Water: Clinically shown by 150+ studies to soothe, soften and calm the skin.

How to Use:
Use the pipette to apply a few drops to the face, neck and eye area in the morning and evening before your usual skin care routine.

Brand Story:
Dermatologist Recommended Skincare. Rooted in dermatology and hydrotherapy, Avène has over 275 years of expertise in the management of sensitive skin with clinically proven efficacy. At the heart of every formula is Avène Thermal Spring Water, the power behind Avene's sensitive skin leadership and care for various skin conditions.
Scent: Unscented
Health Facts: Contains Vitamin B5, Alcohol-Free, Contains Glycerin, Paraben-Free, Silicone-Free, Aluminum-Free, No Fragrance Added, Sulfate-Free, Artificial Fragrance-Free, Talcum-Free
Product Warning: Eye irritant
Product Form: Gel
Beauty Purpose: Deep Hydration, Sensitive Skin, Skin Texture Improvement, Damage Repair, Soothing, Nourishing, Calming, Hydrating
Recommended Skin Type: Very Dry, Mature, Sensitive, Extra Sensitive, Oily, Normal, Dry, Acne-Prone, Combination
Features: Dermatologist Recommended, Non-Drying, Moisturizing, Dermatologist Tested
TCIN: 94582250
UPC: 3282770393620
Item Number (DPCI): 037-14-2688
Origin: Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Ingredients:

avene thermal spring water (avene aqua), glycerin, pentylene glycol, propanediol, 1,2-hexanediol, panthenol, 4-t-butylcyclohexanol, octyldodecanol, pantolactone, betaine, citric acid, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, polysorbate 60, sodium citrate, sorbitan isostearate, water (aqua), xanthan gum

Allergens & Warnings:

WARNINGS: For external use only. Avoid contact with eyes.

Shipping details

Estimated ship dimensions: 4.09 inches length x 1.61 inches width x 1.61 inches height
Estimated ship weight: 0.26 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: Can I apply this to damp or dry skin?

submitted by Ms1124 - 5 months ago
  • A: Hello MS1124, thank you for your question about our Avene Cicalfate+ Intensive Skin Restorative Face Serum- 13.2 fl oz @ Target. We would greatly appreciate the opportunity to speak with you directly. Please email our customer care team at info@aveneusa.com so we can assist you further. Be sure to include TGTPR26 in the subject line of your email. Kind Regards, The Avène Customer Care Team

    submitted byPierre Fabre - 4 months ago
    Brand expert

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Guests are saying

This serum is highly praised for its soothing and hydrating properties, making it ideal for sensitive and reactive skin types. Many guests have found it effective in calming conditions like rosacea and dermatitis, while also enhancing skin texture and moisture retention. However, concerns about the packaging and some ingredient changes have been noted. Overall, it serves as a valuable addition to skincare routines, especially for post-procedure recovery.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.6 out of 5 stars with 449 reviews
    effectiveness: 4.25 out of 5
    quality: 4.25 out of 5
    value: 3.5 out of 5
    60% would recommend
    5 recommendations
    3 out of 5 stars
    26 July, 2026
    originally posted on Avene USA
    Image

    Good product, horrible packaging

    I’ve used this product for awhile and it’s great for keeping my rosacea flares under control/soothing my skin. However, the newer packaging makes this product impossible to travel with or keep closed. The dropper top will not stay screwed down, so you have to be careful when picking up the product because it isn’t secure. This also means you can’t travel with the product because it spills. Worst, this means your product is exposed to air and potentially not as effective. Please, please, please change packaging again.
    1 reply from Avene Customer Care team - 22 days ago
    Hello Nicole, We're sorry to hear about your experience with the Cicalfate+ Intensive Restorative Serum. We would greatly appreciate the opportunity to speak with you directly. Please email our customer care team at info@aveneusa.com so we can assist you further. Be sure to include AVUSA26 in the subject line of your email.
    Nicole7245
    1 guest found this review helpful. Did you?
    2 out of 5 stars
    Thumbs down graphic, would not recommend
    7 July, 2026Verified purchase

    Ok. Not great.

    Not enough moisture compared to the cream.
    1 reply from Pierre Fabre team - 1 month ago
    Hello Jes, We're sorry to hear about your experience with our Avene Cicalfate+ Intensive Skin Restorative Face Serum @ Target. We would greatly appreciate the opportunity to speak with you directly. Please email our customer care team at info@aveneusa.com so we can assist you further. Be sure to include TGT26 in the subject line of your email. Kind Regards, The Avène Customer Care Team
    effectiveness: 2 out of 5
    quality: 2 out of 5
    value: 2 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    3 July, 2026

    Hurt

    Should be good for sensitive compromised skin. Currently I have that so ran to the store to get this and the cream. Nothing but burning and stinging so bringing it back.
    1 reply from Pierre Fabre team - 1 month ago
    Hello Victoria, We're sorry to hear about your experience with our Avene Cicalfate+ Intensive Skin Restorative Face Serum @ Target. We would greatly appreciate the opportunity to speak with you directly. Please email our customer care team at info@aveneusa.com so we can assist you further. Be sure to include TGT26 in the subject line of your email. Kind Regards, The Avène Customer Care Team
    Did you find this review helpful?
    1 out of 5 stars
    23 June, 2026
    originally posted on Avene USA
    Image

    (no review title)

    The ingredients did change so please read. It now contains propanediol, an ingredient that I am allergic to. The previous version did not.
    1 reply from Avene Customer Care team - 2 months ago
    Hello IKO82, We're sorry to hear about your experience with the Cicalfate+ Intensive Restorative Serum. We would greatly appreciate the opportunity to speak with you directly. Please email our customer care team at info@aveneusa.com so we can assist you further. Be sure to include AVUSA26 in the subject line of your email.
    IK082
    Did you find this review helpful?
    1 out of 5 stars
    14 June, 2026
    originally posted on Avene USA
    Image

    Stinging, and burning

    I’m so frustrated with what Avène is doing lately. First they ruined the original Extremely Gentle Cleansing Lotion; Tolerance Emulsion, Fragrance free Facial gel wash,, and now this "Recovery" serum is a nightmare if your barrier is actually compromised or if you use Retin-A.They packed this with a synthetic gel thickener (Sodium Acryloyldimethyl Taurate Copolymer) and heavy glycols. If your skin is raw or thinned out at all, those glycols drag that taurate polymer deep into your skin way too fast.The second it hit my chin, it triggered intense, fiery chemical burning, stinging, and bright red flushing. It literally shocks your nerve endings. I had to rush to the sink to wash it. Avène used to be trusted because their formulas were bare-bones, inert, and safe. Now, they are ruining their brand just to chase trendy, lightweight gel textures. If your skin is genuinely reactive, skip this completely. Avène, please go back to the safe, simple chemistry that actually made you famous!
    1 reply from Avene Customer Care team - 2 months ago
    Hello Rihanna, We're sorry to hear about your experience with the Cicalfate+ Intensive Restorative Serum. We would greatly appreciate the opportunity to speak with you directly. Please email our customer care team at info@aveneusa.com so we can assist you further. Be sure to include AVUSA26 in the subject line of your email.
    Rihanna
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    24 May, 2026
    originally posted on Avene USA
    Image

    Great for Aging Skin

    I tried this because my daughter loves the Cicalfate cream. I like the restorative skin barrier properties. It is lightweight and absorbs well.
    CherylF
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    12 May, 2026Verified purchase

    Maybe The Best Product Ever

    I never write reviews, but this product deserves one. My facial skin is very odd in that products that generally work for most people do not work for me. The usual suggestion of using a thick ceramide cream/moisturizer to repair the skin barrier does not work for me, and those moisturizers just sit on the top of my skin causing my skin to become irritated, especially in the perioral region. Hyaluronic acid and niacinamide do not work for me either. Even gentle skin cleaners or even cleansing with just water causes my face to dry out and become irritated. I used this at night and the irritated feeling around my mouth region stopped right away. I have been using this in the AM and PM just to keep my skin relieved.
    J S
    effectiveness: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    8 May, 2026
    originally posted on Avene USA
    Image

    amazing repair

    This serum has become an essential part of my post‑procedure and recovery routine. It delivers instant soothing and deep hydration while absorbing quickly into the skin. I especially love using it after laser treatments or when my barrier feels fragile. Paired with the Cicalfate Restorative Protective Cream, it creates an incredibly effective repair system that leaves my skin calm, comfortable, and visibly healthier.
    michellesskinnotes
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    12 April, 2026
    originally posted on Avene USA
    Image

    So gentle!

    Love this for my skin barrier! Avene products are the only ones that don’t irritate my skin.
    Brenda S
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    7 April, 2026
    originally posted on Avene USA
    Image

    OUTSTANDING & cleared my dermatitis

    This quite literally saved my skin and a few hundred dollars at a dermatologist. I unfortunately used a toner all over my face that I had not patched, tested and broke out with contact dermatitis on my face and neck. Having reactive skin, everything that was recommended to put on such as, calming, barrier creams, mild cleansers, barrier, protectant ointment, etc., absolutely made my skin sting and react worse. Something I learned was that when you have a reactive skin type, anything that traps he makes it worse. I went two full days with nothing on my face, not being able to do anything except splash water. So I went and asked my trusted friend ChatGPT…. This was one of the products that was recommended. It was recommended because it wasn’t humectant heavy. Wouldn’t sit on top of my skin barrier and trap heat, and didn’t contain anything irritating but would help help. Build my barrier back up while also calming down the dermatitis….. well as somebody who dislikes, serums and humectant heavy products like most serums are, I could’ve poured this whole bottle on my entire face. It was so soothing, silky, like nothing I had felt before, did not feel sticky, tacky or anything of that nature. It glided across my entire face and neck where the dermatitis was, and sunk right into my skin within a few minutes. My face instantly felt calm and unbothered. Aside from washing my face with simply water, for 40s I only applied this morning and night and everything disappeared. I wish they would make a lightweight version moisturizer of this same product that doesn’t trap heat, because this product is absolutely a 10 out of 10 out of 10 out of 10.
    Jenni’s
    3 guests found this review helpful. Did you?
    4 out of 5 stars
    31 March, 2026Verified purchase

    Packaging

    I love this product but the tubing of it is not manageable. The dropper pulled apart from the lid. My partner is in engineering and construction and said to never buy a product from the company again due to the packaging. It was halfway full when the dropper broke which led to air getting into the container and it not being fully concealed again. I wish the packaging would be better for the long term
    Gabby
    Did you find this review helpful?
    5 out of 5 stars
    28 March, 2026
    originally posted on Avene USA
    Image

    Repurchase

    I use the cicablast cream at night and just started to use this serum during the day. It is hydrating and soothing to my skin. Friendly under makeup and no need for extra hydration.
    RASSY
    Did you find this review helpful?
    3 out of 5 stars
    23 March, 2026
    originally posted on Avene USA
    Image

    First time using it

    It’s a little sticky which I hope is just because it hasn’t soaked in it. Excited to see the results
    1 reply from Avene Customer Care team - 5 months ago
    Hello Margot, We're sorry to hear about your experience with the Cicalfate+ Intensive Skin Restorative Serum. We would greatly appreciate the opportunity to speak with you directly. Please email our customer care team at info@aveneusa.com so we can assist you further. Be sure to include AVUSA26 in the subject line of your email.
    Mms1124
    Did you find this review helpful?
    5 out of 5 stars
    23 March, 2026
    originally posted on Avene USA
    Image

    Best barrier repair serum

    This is by far the best barrier repair serum Iv ever used . Iv used many serums and nothing compares to this . Immediately it soothes and restores my skin . It does not sting and it calms my skin and soothes redness . Perfect serum for sensitive skin
    Jes Lyne
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    21 March, 2026Verified purchase

    Great hydrating serum

    LOVE IT!
    Marie
    effectiveness: 5 out of 5
    quality: 5 out of 5
    value: 3 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    21 March, 2026
    originally posted on Avene USA
    Image

    NOT THE SAME AS THE OLD PACKAGING

    I've used the product for a long time, the product in the new packaging is NOT the same. It has a much stronger scent, it is sticky and it causes my rosacea to flair.
    1 reply from Avene Customer Care team - 5 months ago
    Hello Terri, We're sorry to hear about your experience with the Cicalfate+ Intensive Skin Restorative Serum. We would greatly appreciate the opportunity to speak with you directly. Please email our customer care team at info@aveneusa.com so we can assist you further. Be sure to include AVUSA26 in the subject line of your email.
    terriB
    1 guest found this review helpful. Did you?
    2 out of 5 stars
    16 March, 2026
    originally posted on Avene USA
    Image

    Defective bottle

    As another user said, defective bottle / packaging - cap does not fully screw shut and thus spills everywhere if you bring it when traveling. This is the second bottle I've bought that this has happened with
    1 reply from Avene Customer Care team - 5 months ago
    Hello Lily, We're sorry to hear about your experience with Cicalfate+ Intensive Skin Restorative Serum. We would greatly appreciate the opportunity to speak with you directly. Please email our customer care team at info@aveneusa.com so we can assist you further. Be sure to include AVUSA26 in the subject line of your email.
    1234
    Did you find this review helpful?
    5 out of 5 stars
    8 March, 2026
    originally posted on Avene USA
    Image

    Calming

    Very calming to my red and irritated rosacea skin.
    Annewink
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    8 March, 2026Verified purchase

    PD & Rosacea girls buy this now

    It really does make a huge difference after one use. Helped my PD and rosacea OVERNIGHT. I am using this with the sinsiru watery sulfur serum, peach slices azelaic acid, and topical ivermectin (lice treatment).
    Arnold Layne
    effectiveness: 5 out of 5
    quality: 5 out of 5
    value: 4 out of 5
    3 guests found this review helpful. Did you?
    2 out of 5 stars
    5 March, 2026
    originally posted on Avene USA
    Image

    Defective bottle

    The serum itself is fine, after a week of use I haven’t seen a noticeable difference but it does feel and smell nice. My issue is with the bottle. The dropper top will not stay closed. Even after tightening multiple times it has unwound itself and caused leaking and product loss. I’m a flight attendant and I bought this specifically to use when I’m on trips and now I’ve lost so much product and can’t even bring it with me to work unless I want to lose more. Really disappointed especially for the price.
    1 reply from Avene Customer Care team - 5 months ago
    Hello Kels, We're sorry to hear about your experience with the Cicalfate+ Intensive Skin Restorative Serum. We would greatly appreciate the opportunity to speak with you directly. Please email our customer care team at info@aveneusa.com so we can assist you further. Be sure to include AVUSA26 in the subject line of your email.
    Kels M
    Did you find this review helpful?

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