Target New ArrivalsHalloweenClothing, Shoes & AccessoriesHome & DecorKitchen & DiningPatio, Lawn & GardenGroceryHousehold EssentialsBabyBeautyTarget Beauty StudioPersonal CareSports & OutdoorsPetsHealthWellnessSchool & Office SuppliesToys & GamesElectronics & TechVideo GamesBooks, Music & MoviesParty SuppliesGift IdeasGift CardsShop by CommunityTarget OpticalDealsClearanceNew ArrivalsBack to SchoolCollegeTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Puffs Plus Lotion Gentle & Soothing Facial Tissue - 2 of 4Puffs Plus Lotion Gentle & Soothing Facial Tissue - 3 of 4Puffs Plus Lotion Gentle & Soothing Facial Tissue - 4 of 4
Puffs Plus Lotion Gentle & Soothing Facial Tissue - 1 of 4

Puffs Plus Lotion Facial Tissue - 4pk/496ct

13 Questions
$6.79 ($1.37/100 count)

Box TypeRectangle
Pack Size4
Count Per Box124

In Stock

Eligible for registries and wish lists
Save 5% every day
With Target Circle™ Card (restrictions apply)

At a glance

About this item

Highlights

  • Puffs softest, most cushiony tissue, with a touch of lotion, to help protect your nose
  • Puffs Plus Lotion helps soothe irritated noses by locking in moisture better than regular tissues
  • Don't let your runny nose run out of Puffs. Sign up for automatic home delivery and save
  • Travel-size pocket tissues fit in small spaces like pockets and purses to defend runny noses anywhere
  • Be ready for cold & flu on-the-go with soft, soothing Puffs Plus Lotion

Description

Puffs Plus Lotion is the perfect tissue for when sore or runny noses need some extra softness for any cold, flu, or allergy. Puffs Plus Lotion facial tissues lock in moisture better, to help soothe irritated skin commonly caused from rough or thin tissues. It's no wonder that Puffs Plus Lotion is America's #1 selling Lotion Tissue brand. Dermatologist tested to be gentle on sensitive skin. Order with Drive Up and we'll bring it right out to your car. A nose in need deserves Puffs indeed!
Health Facts: Dye-Free, Non-Toxic
Sheets Per Roll: 124
Disposability: Do not flush
Package Quantity: 4
Container Shape: Rectangle
Industry or Government Certifications: Sustainable Forestry Initiative Certified
Ply: 2-Ply
Material: Wood Cellulose
Features: Dermatologist Tested, Lotion
TCIN: 78603906
UPC: 037000586005
Item Number (DPCI): 253-07-0275
Origin: Made in the USA and Imported
If the item details aren’t accurate or complete, we want to know about it.

Ingredients:

lotion contains: mineral oil, cetearyl alcohol, paraffin and steareth-2.

Shipping details

Estimated ship dimensions: 14.9 inches length x 8.9 inches width x 4.8 inches height
Estimated ship weight: 2.6 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: How do I know if this are the cube boxes

submitted by DontKnow - 9 years ago
  • A: Hi - thanks for your question! There's a helpful "Specifications" section which shows detailed information about this Puffs product. The shape of these are rectangular.

    submitted byPuffs - 6 years ago
    Brand expert
  • A: I have bought these before. They are the long boxes not the cube ones. The cubes thend to have less in them. This is they only type of tissues that I use. I have really bad allergies and these tissues keep my nose from drying out and getting red. Love them!

    submitted byLilly - 9 years ago
  • A: Also, there is a picture that shows the size of the box on the label. Enjoy!

    submitted byLilly - 9 years ago
  • A: They have both the cube, and rectangle option. They also have soft packs. I typically get the cubes for my van so they fit where I like them, and the rectangles for house.

    submitted byJannae - 3 years ago
  • A: Thank you!!!!!!!!!!!!!

    submitted byDontKnow - 9 years ago

Q: Is there eucalyptus or vicks vapor rub in the tissues? I bought an 8 pack and all smelled this way and I'm allergic. Didn't see it listed. Can't use any of them

submitted by Kelly - 1 year ago
  • A: I am absolutely getting that smell!!!! So annoying

    submitted bygummylover - 5 months ago
  • A: Oh they definitely have that smell. Has to stop buying them.

    submitted byKelly - 7 months ago
  • A: No, it contains soothing lotion with Aloe, Vitamin E, and Shea Butter.

    submitted byPuffs - 1 year ago
    Brand expert

Q: What are the dimentions of on rectangular box? I'm trying to see if I can find a way to mount a holder to the wall to save counter space.

submitted by SMM - 2 years ago
  • A: It will depend on the box size. For the cube box it's 4.370" L x 4.134" W x 5.000" H. For the regular box it's: 8.898" L x 3.110" W x 4.764" H. For the Family Box it's 8.900" L x 4.800" W x 13.300" H.

    submitted byPuffs - 2 years ago
    Brand expert

Q: Why is the 6-pack tissue box advertised as 744 total tissues if the count per box is 72?

submitted by Anna - 9 months ago
  • A: Hi! Thank you for your question. We appreciate your interest in our products. To clarify, each box of Puffs Plus Lotion Mega Cubes contains 72 tissues. If you have a 6-box pack, that would total 432 tissues (72 tissues x 6 boxes = 432 tissues). However, if you have the Family Size, each box contains 124 tissues, which would total 744 tissues for a 6-box pack (124 tissues x 6 boxes = 744 tissues). We apologize for any confusion this may have caused! If you have any more questions, feel free to ask!

    submitted byPuffs - 9 months ago
    Brand expert
  • A: I've been buying the six pack thinking it was a better deal. I just looked at the bottom of my box and it only has 72 tissues in it. I've been duped. As of now, the four pack is the better deal.

    submitted byDee - 6 months ago

Q: How are there 744 tissues total when each box only contains 72 tissues for the 6 box pack.

submitted by Vs - 11 months ago
  • A: Hi! Thank you for your question. We appreciate your interest in our products. To clarify, each box of Puffs Plus Lotion Mega Cubes contains 72 tissues. If you have a 6-box pack, that would total 432 tissues (72 tissues x 6 boxes = 432 tissues). On the other hand, the Family size has 124 sheets each, which is 744 in total if you have a 6-box pack. It seems there may have been a misunderstanding regarding the total count of 744 tissues. We apologize for any confusion this may have caused! If you have any more questions, feel free to ask!

    submitted byPuffs - 9 months ago
    Brand expert
  • A: I've been buying the six pack thinking it was a better deal. I just looked at the bottom of my box and it only has 72 tissues in it. I've been duped. As of now, the four pack is the better deal.

    submitted byDee - 6 months ago

Q: What is the measurement of the new mega cube?

submitted by Evelyn - 4 months ago
  • A: Thank you for reaching out and asking your question. We don’t have the measurements details for this Mega Cube available on our end. Some retailers, such as Amazon, may list those measurements on their product pages, so we recommend checking with the retailer of your choice for the most complete information.

    submitted byPuffs - 3 months ago
    Brand expert

Q: How many ply are these

submitted by Puffs plus - 6 months ago
  • A: Hi there! Thank you for reaching out and for your question. Our Puffs Plus Lotion are 2-Ply! You can find this information printed on the bottom of the package.

    submitted byPuffs - 5 months ago
    Brand expert

Q: Are they folded to pop up?

submitted by Harriett - 7 months ago
  • A: Thank you for your question! Our small boxes are designed so that the tissues pop up one after the other for convenient dispensing. However, our Family Boxes are designed for a reach-in, meaning the tissues do not pop up sequentially in those larger boxes. Hope this clarifies how our different box sizes are designed! Best regards,

    submitted byPuffs - 6 months ago
    Brand expert

Q: Kleenex is FSC certified (Forest Stewardship Council), supporting responsible forestry. Kleenex is made with 100% of its paper sourced from responsibly managed forests. Is Puffs FSC certified?

submitted by Hobbesmum - 1 year ago
  • A: We only use pulp certified by the Forest Stewardship Council® and support FSC® in their work to increase adoption of FSC products. These standards ensure that we are protecting wildlife and contributing to thriving local communities.

    submitted byPuffs - 1 year ago
    Brand expert

Q: Is tissue 2 or 3 ply?

submitted by Pauli - 1 year ago
  • A: All Puffs are 2 Ply.

    submitted byPuffs - 1 year ago
    Brand expert

Additional product information and recommendations

Guests also viewed

Skip to next section

Guests are saying

Puffs Plus Lotion tissues are highly praised for their exceptional softness and soothing qualities, making them a favorite among guests, especially during allergy season or when feeling under the weather. The lotion-infused tissues help prevent irritation and dryness, providing comfort for sensitive skin. Many guests appreciate the durability and absorbency, making these tissues a reliable choice for everyday use. However, some concerns have been raised about quality consistency and packaging issues.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.6 out of 5 stars with 19548 reviews
    quality: 4.49 out of 5
    softness: 4.58 out of 5
    value: 4.34 out of 5
    85% would recommend
    554 recommendations
    3 out of 5 stars
    9 September, 2026Verified purchase

    (no review title)

    Too thin.
    Lynn
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    6 September, 2026Verified purchase

    Great for the skin!

    Good as it gets! If necessary, I’ll opt for the Vicks style when I have a cold but always the Kleenex brand.
    Lindsay18
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    30 August, 2026
    originally posted on puffs.com
    Image

    I love these tissues.

    Love the softness and strength of these tissues. Perfect for my family. I’m just sad that I can’t find them in travel size anywhere. I used to buy them and always had them with me.
    Orchydia
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    28 August, 2026Verified purchase

    Soothing to touch

    my grandson loves the softness and the soothing touch as I do and the lotion in the tissue helps avoid the skin under the nose from chafing.
    1 reply from Puffs team - 9 days ago
    Hi, thank you for your wonderful feedback! We're thrilled to hear you love our Puffs Tissues. Your positive experience means a lot to us!
    Shuriel
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    26 August, 2026Verified purchase

    Soft and gentle

    A must in our house during allergy season. Super soft and the lotion helps keep our noses from drying out and becoming irritated.
    aj
    quality: 5 out of 5
    softness: 5 out of 5
    value: 4 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    25 August, 2026Verified purchase

    Puffs Plus Lotion

    I love Puffs Plus Lotion. It is very soft and smooth. I even use it on my face to clean. I make sure to keep plenty in stock.
    Joann
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    16 August, 2026Verified purchase

    Amazing!

    Amazing!
    Sarah
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    15 August, 2026Verified purchase

    Best tissue

    Love the softness and gentleness
    Gloria
    quality: 5 out of 5
    softness: 5 out of 5
    value: 4 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    15 August, 2026Verified purchase

    nest one ever

    these are al3aye my go to when im sick. nothing comepar3s. they ar3 so soft and help me breath vetter
    SandraR86
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    12 August, 2026Verified purchase

    (no review title)

    The scent is wonderful for opening passageways
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    11 August, 2026Verified purchase

    (no review title)

    love Puffs plus
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    11 August, 2026Verified purchase

    No raw noses here

    Sending my kid to college and puffs with lotion is the only tissue we use for the sniffles!!
    1 reply from Puffs team - 1 month ago
    Hi, thank you for your wonderful feedback! We're thrilled to hear you love our Puffs Tissues. Your positive experience means a lot to us!
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    11 August, 2026Verified purchase

    Cute Design!

    The product has a nice design and the tissues are a good quality.
    CQ
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    10 August, 2026Verified purchase

    (no review title)

    The best tissues! These tissues are great and more gentle on a sore nose than other tissues.
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    9 August, 2026Verified purchase

    Keeping Away Soreness

    The softness against my nose. Reliable and keeps my nose from getting sore. A must have when sick
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    1 August, 2026Verified purchase

    Didnt get

    Didn’t receive my 360 order and they aren’t doing anything about it!
    Lalaschwany
    quality: 1 out of 5
    softness: 1 out of 5
    value: 1 out of 5
    Did you find this review helpful?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    26 July, 2026Verified purchase

    Down sizing again !!!!

    Where's the 8 pack?
    quality: 3 out of 5
    softness: 4 out of 5
    value: 3 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    26 July, 2026Verified purchase

    My favorite tissue for allergy season.

    My favorite facial tissue ever. I have bad allergies and sensitive skin. Puffs Plus is soft, durable for a tissue, doesn't irritate my skin, and has a reasonable price.
    1 reply from Puffs team - 2 months ago
    Hi, thank you for your wonderful feedback! We're thrilled to hear you love our Puffs Tissues. Your positive experience means a lot to us!
    quality: 5 out of 5
    softness: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    4 out of 5 stars
    24 July, 2026
    originally posted on puffs.com
    Image

    Overpackaged.

    I like these in the cube box. But I wish the company would quit overwrapping them in heavy plastic. So unnecessary and not environmentally responsible.
    1 reply from Customer Care team - 1 month ago
    Thank you for sharing your feedback with us, Ginny. We appreciate you letting us know how you feel about Puffs Plus Lotion, especially regarding the heavy plastic overwrap. While we’re glad you enjoy the cube box format, we understand your concern about unnecessary packaging. For context, the plastic overwrap is 100% recyclable, but we hear you — even recyclable materials can feel excessive when you’re trying to make environmentally responsible choices. Feedback like yours helps us evaluate how we can balance product protection with sustainability.
    1 reply from Customer Care team - 1 month ago
    Thank you for sharing your feedback with us, Ginny. We appreciate you letting us know how you feel about Puffs Plus Lotion, especially regarding the heavy plastic overwrap. While we’re glad you enjoy the cube box format, we understand your concern about unnecessary packaging. For context, the plastic overwrap is 100% recyclable, but we hear you — even recyclable materials can feel excessive when you’re trying to make environmentally responsible choices. Feedback like yours helps us evaluate how we can balance product protection with sustainability.
    GinnyQ
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    24 July, 2026

    Hurts your nose. leaves behind residue. has no lotion at all. Kleenex is by far superior. First and last time buying these.

    Dry
    1 reply from Puffs team - 1 month ago
    Thank you for sharing your feedback with us, Ariana. We’re sorry to hear that your Puffs Plus Lotion tissues felt dry, left residue, and even hurt your nose. That’s definitely not the experience we want you to have — and it’s frustrating, especially when you expected a lotion‑enhanced tissue and instead got something that felt rough. Puffs Plus Lotion is designed to be soothing and gentle, so if your box felt dry or lacked lotion, that usually points to a production or batch issue. Residue on the skin can also happen when the tissue layers aren’t bonded correctly, and we appreciate you calling that out. We’d like to look into this further and help make it right. Please reach out to our Puffs team at 1‑800‑777‑8337 so we can gather more details from your specific box.
    Ariana
    quality: 1 out of 5
    softness: 1 out of 5
    value: 1 out of 5
    Did you find this review helpful?

    Get top deals, latest trends, and more.