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Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 2 of 4Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 3 of 4Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 4 of 4
Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 1 of 4

Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 4oz

6 Questions
New at  target 
$6.29
 
Size4oz

In Stock

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At a glance

About this item

Highlights

  • Desitin Daily Defense Diaper Rash Cream to soothe, treat & prevent baby diaper rash
  • The fast-acting formula of this infant diaper rash cream prevents diaper rash from the first use
  • #1 choice for diaper rash relief by Pediatricians & parents, it is both easy to apply and remove
  • It instantly forms a protective layer on your baby's skin for diaper rash relief and prevention
  • Made with 13% zinc oxide, it is hypoallergenic and specially formulated for babies' tender skin

Description

Use Desitin Daily Defense Diaper Rash Cream every day to soothe, treat and prevent baby diaper rash. This hypoallergenic and pediatrician-tested formula instantly forms a protective barrier on your baby's tender skin and is clinically shown to provide diaper rash relief. The daily diaper rash cream is designed to work at the first hint of diaper rash to help heal and soothe your baby's skin. Made with fast-acting formula containing 13% zinc oxide skin protectant, this barrier cream helps seal out wetness and provides protection from the first use. It is dermatologist-tested and free of parabens, phthalates, fragrances and dyes, so it's gentle enough to use at every diaper change. The #1 choice of pediatricians and parents, the creamy formula goes on smoothly and wipes off easily, making Desitin Daily Defense Diaper Rash Cream your trusted partner for treating diaper rash from the first signs.
Scent: Unscented
Suggested Age: Newborn and Up
Health Facts: Paraben-Free, Aluminum-Free, No Fragrance Added, Phthalate-Free, Dye-Free, Contains Zinc Oxide, Hypoallergenic
Active Ingredient Strength Value: 13
Product Form: Cream
Primary Active Ingredient: Zinc Oxide
Package Quantity: 1
Features: Soothing, Pediatrician Tested, Dermatologist Tested
TCIN: 13682489
UPC: 074300003016
Item Number (DPCI): 007-08-0484
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

zinc oxide' '13.0%

Purpose

Skin protectant

Uses

• helps treat and prevent diaper rash • protects chafed skin due to diaper rash and helps seal out wetness

Directions

Directions • change wet and soiled diapers promptly • cleanse the diaper area • allow to dry • apply cream liberally as often as necessary, with each diaper change, especially at bedtime or anytime when exposure to wet diapers may be prolonged

Other information

Sustainable Forestry Initiative (SFI) - Certified Chain of Custody At Least 10% Certified Forest Content - www.sfiprogram.org - SFI-00311, May stain clothing, © J&JCI 2018

Inactive ingredients

inactive ingredients: water, mineral oil, petrolatum, beeswax, dimethicone, sorbitan sesquioleate, microcrystalline wax, peg-30 dipolyhydroxystearate, aloe barbadensis leaf extract, glycerin, tropolone, tocopheryl acetate, 1,2-hexanediol, caprylyl glycol, magnesium sulfate, potassium hydroxide, phenoxyethanol

Ingredients:

inactive ingredients: water, mineral oil, petrolatum, beeswax, dimethicone, sorbitan sesquioleate, microcrystalline wax, peg-30 dipolyhydroxystearate, aloe barbadensis leaf extract, glycerin, tropolone, tocopheryl acetate, 1,2-hexanediol, caprylyl glycol, magnesium sulfate, potassium hydroxide, phenoxyethanol

Shipping details

Estimated ship dimensions: 1.93 inches length x 2.38 inches width x 6.21 inches height
Estimated ship weight: 0.31 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: Hi, is this product supposed to have a tamper seal.

submitted by Hellojello - 8 months ago

  • A: Hello. Yes this product has tamper seal included.

    submitted byKenvue - 8 months ago
    Brand expert

Q: Can it be used on toddlers as well?

submitted by Samantha - 2 years ago

  • A: Hi Samantha. This product can also be used by toddlers if you want to more about this you may go to our website https://www.desitin.com/diaper-rash-products/daily-defense-zinc-oxide-cream.

    submitted byKenvue - 2 years ago
    Brand expert

Q: Is it in a tube or in a jar?

submitted by CheapGuy - 2 years ago

  • A: Hello. Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 4oz is in a tube packaging. Thank you.

    submitted byKenvue - 2 years ago
    Brand expert

Q: Is it odorless? I need it for an adult with a terrible tash but I've always hated the scent

submitted by Denise1954 - 2 years ago

  • A: No Fragrance Added.

    submitted byKenvue - 2 years ago
    Brand expert

Q: Does the jar have a protective seal? Mine arrived without a seal or foil protecting the cream. Just a target tape over the lid so it wouldn’t spill or pop open during shipping.

submitted by Curious - 2 years ago

  • A: Thank you so much for bringing this to our attention! We appreciate your review and would like to learn more about your experience. When you have a moment, please give us a call at 1-800-720-3843. Our team is available Monday-Friday, 9:00 am-5:30 pm EST. We hope to hear from you soon!

    submitted byKenvue - 2 years ago
    Brand expert

Q: does this stain Destin Diaper rash cream

submitted by YogaKat - 3 years ago

  • A: Great question! This product is not made with dyes. Zinc Oxide, although not a dye, imparts a white color to the formula, and when used on the skin.

    submitted byKenvue - 3 years ago
    Brand expert
See all questions (6)

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Guests are saying

Desitin Daily Defense Cream is a highly recommended solution for diaper rash, praised for its effectiveness in soothing and preventing irritation. Guests appreciate its smooth texture, easy application, and the fact that a little goes a long way, making it a cost-effective choice. The cream is gentle on sensitive skin, free from harsh ingredients, and comes in convenient packaging, making it a must-have for parents looking to keep their baby's skin healthy and protected.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.7 out of 5 stars with 4162 reviews
    89% would recommend
    128 recommendations
    5 out of 5 stars
    Thumbs up graphic, would recommend
    18 August, 2026Verified purchase

    Great diaper cream

    Baby had a rash and in 1-2 days was gone. Used overnight for extra protection. Great value as a little goes a long way.
    Dl
    Did you find this review helpful?
    5 out of 5 stars
    2 August, 2026
    originally posted on influenster.com
    Image

    Must have!

    A must have if you have a diaper wearing little human around. We use it with every diaper change. Great for price. I have tried other diaper creams but this was recommended by the pediatrician and I can see why.
    SusanF
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    28 July, 2026
    originally posted on influenster.com
    Image

    Effective diaper rash cream for daily use

    This Desitin diaper rash cream has been amazing. My child has used it every day since birth, and it always worked well to help protect and soothe their skin. The cream has a thick texture, so you only need to apply a small amount each time, which makes one tube last a long time. If i have another baby in the future, i will definitely continue using this product.
    AnhN
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    16 July, 2026
    originally posted on influenster.com
    Image

    A must have!

    A must have baby essential! Desitin always clears up my baby’s rash super quick! I recommend it for all baby shower gifts especially to new expecting parents!
    AshtonA
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    11 July, 2026
    originally posted on influenster.com
    Image

    Excellent product

    Its application is very easy. It has excellent effectiveness. Its ingredients are free of animal cruelty and are not harmful. Its texture is smooth. Her performance is excellent, as I use her frequently with my princesses. And no excessive amount is needed when using it.
    IveH
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    25 June, 2026
    originally posted on influenster.com
    Image

    Classic diaper cream, great for everyday!

    Solid diaper cream for everyday! I stock up on this to send to daycare. Easy to open and close the packaging with one hand. I only wish they made a bigger tube!
    TeresaE
    Did you find this review helpful?
    5 out of 5 stars
    8 June, 2026
    originally posted on influenster.com
    Image

    A reliable and effective cream.

    Excellent cream to protect and soothe the skin. It is soft, easy to apply and helps keep baby’s skin healthy. A reliable and effective cream. Protects the baby’s delicate skin and leaves a soft feeling.
    DarielaS
    Did you find this review helpful?
    5 out of 5 stars
    24 May, 2026
    originally posted on influenster.com
    Image

    Very effective

    I like it very much for the day it is easy to remove durable prevents burns by the diaper it has a soft feeling and easy to apply the quality is perfect I highly recommend it for babies and its value is not high therefore it is a very good option for babies
    ElisangelaB
    Did you find this review helpful?
    5 out of 5 stars
    20 May, 2026
    originally posted on influenster.com
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    Multi use

    Unlike the thick white paste this petroleum version goes on smooth and clear without the messy residue or heavy medicinal smell. It works wonder for standby soothing diaper rash and irritated skin on the kids, but just is amazing for adults dealing with severely dry hands cracked heels or friction chafing.
    MadelineR
    Did you find this review helpful?
    5 out of 5 stars
    18 May, 2026
    originally posted on influenster.com
    Image

    The most effective diaper rash Cream

    I been using Desitin for years starting with my first son. This is most effective for treating and preventing diaper rashes and great for sensitive skin. I highly raise the zinc oxide formula ability to clear up irritation and redness so fast.
    ShanaeS
    Did you find this review helpful?
    5 out of 5 stars
    15 May, 2026
    originally posted on influenster.com
    Image

    Very portable

    Very easy to use. Its very easy to store. Very easy to bring on the go with you and its very efficient at preventing diaper rashes. Very good to keep in the diaper bag.
    MeganC
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    14 May, 2026
    originally posted on influenster.com
    Image

    It is very effective when it comes to diaper pink,

    I come to recommend this cream for its effectiveness and performance to my babies, it has helped them a lot right now that they have been pink, I love its functionality and its smell.
    KatherineR
    Did you find this review helpful?
    5 out of 5 stars
    29 April, 2026
    originally posted on influenster.com
    Image

    Best daily use

    Desitin Daily Defense is the best way to go. If you have a baby that's sensitive to rashes, the daily defense is the perfect product for every diaper change. We use it day and night and the difference it makes is night and day!! We love the 16Oz tub because we use so much of it but always keep a tube handy in the diaper bag. The one downside is, like most effective creams, it is very difficult to remove from fabrics :(
    MottyA
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    29 April, 2026
    originally posted on influenster.com
    Image

    A Must have in diaper bag!

    I have been using desitin diaper rash crram since day one for my baby and it did the job pretty well. My baby never had any rash issues. Infact pediatrician said she has the cleanest bumb, lol! Definitely recommended.
    ShifaliM
    Did you find this review helpful?
    5 out of 5 stars
    19 April, 2026
    originally posted on influenster.com
    Image

    Good .producto ..

    excellent product to combat burns .produced by diapers ..it can be used in any type of puel of babies and other people as well..its .color is white and good testure .it has such a good paking.
    DialenaS
    Did you find this review helpful?
    5 out of 5 stars
    17 April, 2026
    originally posted on influenster.com
    Image

    The best

    I recommend this cream. I use it on my baby daily; it lasts a very long time, absorbs very easily, and doesn't bother my baby. It's the perfect size to be stored anywhere. Its performance is 100/10.
    PaulovaO
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    14 April, 2026Verified purchase

    Better than aquaphor diaper cream

    I like this better than aquaphor diaper cream bc it’s thicker, aquaphor is runny almost and doesn’t keep a thick layer for protection
    Ava
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    4 April, 2026
    originally posted on influenster.com
    Image

    Clears diaper rash SO fast

    This stuff works!!! Since my toddler was a baby and he had started to get a diaper rash, I put this on and it’s typically either better or gone by the next diaper change or morning. It’s thick so it stays out and protects his skin, especially overnight. A little goes a long ways. I always have this on hand
    CarlyS
    Did you find this review helpful?
    5 out of 5 stars
    1 April, 2026
    originally posted on influenster.com
    Image

    Diaper rash cream

    I love using this for toddler especially because it helps soothes his skin keeping him rash free and when he has a rash it ittmedjally works I try using every time I see redness appearing helps him feel better and the residue afterwards you feel a lil bit but not much does its job easy to dipsense and easy to store anywhere.
    JenniferH
    Did you find this review helpful?
    5 out of 5 stars
    25 March, 2026
    originally posted on influenster.com
    Image

    A little goes a long way - protects and soothes sk

    I’ve been using this cream for a while and honestly. It works so well! It’s super gentle on the skin and perfect for daily use. I love that it helps prevent and soothe irritation right way. The texture is smooth and easy to apply, not too thick like other diaper creams. It creates a protected, thanks to the zinc oxide. I also like that it’s hypoallergenic and safe for sensitive skin, which gives me peace of minds
    AnaliiiiL
    Did you find this review helpful?

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