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Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 4oz - 2 of 4Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 4oz - 3 of 4Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 4oz - 4 of 4
Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 4oz - 1 of 4

Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 4oz

$6.29

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At a glance

About this item

Highlights

  • Desitin Daily Defense Diaper Rash Cream to soothe, treat & prevent baby diaper rash
  • The fast-acting formula of this infant diaper rash cream prevents diaper rash from the first use
  • #1 choice for diaper rash relief by Pediatricians & parents, it is both easy to apply and remove
  • It instantly forms a protective layer on your baby's skin for diaper rash relief and prevention
  • Made with 13% zinc oxide, it is hypoallergenic and specially formulated for babies' tender skin

Description

Use Desitin Daily Defense Diaper Rash Cream every day to soothe, treat and prevent baby diaper rash. This hypoallergenic and pediatrician-tested formula instantly forms a protective barrier on your baby's tender skin and is clinically shown to provide diaper rash relief. The daily diaper rash cream is designed to work at the first hint of diaper rash to help heal and soothe your baby's skin. Made with fast-acting formula containing 13% zinc oxide skin protectant, this barrier cream helps seal out wetness and provides protection from the first use. It is dermatologist-tested and free of parabens, phthalates, fragrances and dyes, so it's gentle enough to use at every diaper change. The #1 choice of pediatricians and parents, the creamy formula goes on smoothly and wipes off easily, making Desitin Daily Defense Diaper Rash Cream your trusted partner for treating diaper rash from the first signs.
Scent: Unscented
Suggested Age: Newborn and Up
Health Facts: Dye-Free, Contains Zinc Oxide, Paraben-Free, Phthalate-Free, Hypoallergenic, No Fragrance Added, Aluminum-Free
Active Ingredient Strength Value: 13
Product Form: Cream
Primary Active Ingredient: Zinc Oxide
Package Quantity: 1
Net weight: 4 Ounces
Features: Pediatrician Tested, Soothing, Dermatologist Tested
TCIN: 13682489
UPC: 074300003016
Item Number (DPCI): 007-08-0484
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

zinc oxide' '13.0%

Purpose

Skin protectant

Uses

• helps treat and prevent diaper rash • protects chafed skin due to diaper rash and helps seal out wetness

Directions

Directions • change wet and soiled diapers promptly • cleanse the diaper area • allow to dry • apply cream liberally as often as necessary, with each diaper change, especially at bedtime or anytime when exposure to wet diapers may be prolonged

Other information

Sustainable Forestry Initiative (SFI) - Certified Chain of Custody At Least 10% Certified Forest Content - www.sfiprogram.org - SFI-00311, May stain clothing, © J&JCI 2018

Inactive ingredients

inactive ingredients: water, mineral oil, petrolatum, beeswax, dimethicone, sorbitan sesquioleate, microcrystalline wax, peg-30 dipolyhydroxystearate, aloe barbadensis leaf extract, glycerin, tropolone, tocopheryl acetate, 1,2-hexanediol, caprylyl glycol, magnesium sulfate, potassium hydroxide, phenoxyethanol

Ingredients:

inactive ingredients: water, mineral oil, petrolatum, beeswax, dimethicone, sorbitan sesquioleate, microcrystalline wax, peg-30 dipolyhydroxystearate, aloe barbadensis leaf extract, glycerin, tropolone, tocopheryl acetate, 1,2-hexanediol, caprylyl glycol, magnesium sulfate, potassium hydroxide, phenoxyethanol

Shipping details

Estimated ship dimensions: 6.18 inches length x 2.36 inches width x 1.92 inches height
Estimated ship weight: 0.33 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: How often can this diaper rash cream be used?

submitted by AI Shopping Assistant - 1 month ago

  • A: The cream is safe for daily use during every diaper change to prevent rash.

    submitted byAI Shopping Assistant - 1 month ago
    Ai generated

Q: Does this cream contain any fragrances or dyes?

submitted by AI Shopping Assistant - 1 month ago

  • A: No, the cream is dye-free, fragrance-free, and gentle on sensitive skin.

    submitted byAI Shopping Assistant - 1 month ago
    Ai generated

Q: Is this product dermatologist tested?

submitted by AI Shopping Assistant - 1 month ago

  • A: Yes, it has been dermatologist-tested and is also pediatrician-approved for safety.

    submitted byAI Shopping Assistant - 1 month ago
    Ai generated

Q: Is this product suitable for newborns and older?

submitted by AI Shopping Assistant - 1 month ago

  • A: Yes, the cream is suitable for use on newborns and up, providing gentle care.

    submitted byAI Shopping Assistant - 1 month ago
    Ai generated

Q: What is the primary active ingredient in this diaper cream?

submitted by AI Shopping Assistant - 1 month ago

  • A: The primary active ingredient is 13% zinc oxide, which helps form a protective barrier.

    submitted byAI Shopping Assistant - 1 month ago
    Ai generated

Q: Hi, is this product supposed to have a tamper seal.

submitted by Hellojello - 4 months ago

  • A: Hello. Yes this product has tamper seal included.

    submitted byKenvue - 4 months ago
    Brand expert

Q: Can it be used on toddlers as well?

submitted by Samantha - 1 year ago

  • A: Hi Samantha. This product can also be used by toddlers if you want to more about this you may go to our website https://www.desitin.com/diaper-rash-products/daily-defense-zinc-oxide-cream.

    submitted byKenvue - 1 year ago
    Brand expert

Q: Is it in a tube or in a jar?

submitted by CheapGuy - 1 year ago

  • A: Hello. Desitin Daily Defense Baby Diaper Rash Cream with Zinc Oxide - 4oz is in a tube packaging. Thank you.

    submitted byKenvue - 1 year ago
    Brand expert

Q: Is it odorless? I need it for an adult with a terrible tash but I've always hated the scent

submitted by Denise1954 - 2 years ago

  • A: No Fragrance Added.

    submitted byKenvue - 2 years ago
    Brand expert

Q: does this stain Destin Diaper rash cream

submitted by YogaKat - 3 years ago

  • A: Great question! This product is not made with dyes. Zinc Oxide, although not a dye, imparts a white color to the formula, and when used on the skin.

    submitted byKenvue - 3 years ago
    Brand expert
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Guests are saying

Desitin Daily Defense Cream is a highly effective solution for preventing and treating diaper rash, making it a staple for parents. Its smooth texture allows for easy application, while the gentle formula is safe for sensitive skin. The cream creates a protective barrier that lasts, ensuring your baby's skin remains healthy and irritation-free. With its compact packaging, it's perfect for on-the-go use, making it a must-have in any diaper bag.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.7 out of 5 stars with 4890 reviews
    quality: 4.48 out of 5
    value: 4.53 out of 5
    87% would recommend
    85 recommendations
    5 out of 5 stars
    20 May, 2026
    originally posted on influenster.com
    Image

    Multi use

    Unlike the thick white paste this petroleum version goes on smooth and clear without the messy residue or heavy medicinal smell. It works wonder for standby soothing diaper rash and irritated skin on the kids, but just is amazing for adults dealing with severely dry hands cracked heels or friction chafing.
    MadelineR
    Did you find this review helpful?
    5 out of 5 stars
    18 May, 2026
    originally posted on influenster.com
    Image

    The most effective diaper rash Cream

    I been using Desitin for years starting with my first son. This is most effective for treating and preventing diaper rashes and great for sensitive skin. I highly raise the zinc oxide formula ability to clear up irritation and redness so fast.
    ShanaeS
    Did you find this review helpful?
    5 out of 5 stars
    15 May, 2026
    originally posted on influenster.com
    Image

    Very portable

    Very easy to use. Its very easy to store. Very easy to bring on the go with you and its very efficient at preventing diaper rashes. Very good to keep in the diaper bag.
    MeganC
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    14 May, 2026
    originally posted on influenster.com
    Image

    It is very effective when it comes to diaper pink,

    I come to recommend this cream for its effectiveness and performance to my babies, it has helped them a lot right now that they have been pink, I love its functionality and its smell.
    KatherineR
    Did you find this review helpful?
    5 out of 5 stars
    29 April, 2026
    originally posted on influenster.com
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    Best daily use

    Desitin Daily Defense is the best way to go. If you have a baby that's sensitive to rashes, the daily defense is the perfect product for every diaper change. We use it day and night and the difference it makes is night and day!! We love the 16Oz tub because we use so much of it but always keep a tube handy in the diaper bag. The one downside is, like most effective creams, it is very difficult to remove from fabrics :(
    MottyA
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    29 April, 2026
    originally posted on influenster.com
    Image

    A Must have in diaper bag!

    I have been using desitin diaper rash crram since day one for my baby and it did the job pretty well. My baby never had any rash issues. Infact pediatrician said she has the cleanest bumb, lol! Definitely recommended.
    ShifaliM
    Did you find this review helpful?
    5 out of 5 stars
    19 April, 2026
    originally posted on influenster.com
    Image

    Good .producto ..

    excellent product to combat burns .produced by diapers ..it can be used in any type of puel of babies and other people as well..its .color is white and good testure .it has such a good paking.
    DialenaS
    Did you find this review helpful?
    5 out of 5 stars
    17 April, 2026
    originally posted on influenster.com
    Image

    The best

    I recommend this cream. I use it on my baby daily; it lasts a very long time, absorbs very easily, and doesn't bother my baby. It's the perfect size to be stored anywhere. Its performance is 100/10.
    PaulovaO
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    14 April, 2026Verified purchase

    Better than aquaphor diaper cream

    I like this better than aquaphor diaper cream bc it’s thicker, aquaphor is runny almost and doesn’t keep a thick layer for protection
    Ava
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    4 April, 2026
    originally posted on influenster.com
    Image

    Clears diaper rash SO fast

    This stuff works!!! Since my toddler was a baby and he had started to get a diaper rash, I put this on and it’s typically either better or gone by the next diaper change or morning. It’s thick so it stays out and protects his skin, especially overnight. A little goes a long ways. I always have this on hand
    CarlyS
    Did you find this review helpful?
    5 out of 5 stars
    1 April, 2026
    originally posted on influenster.com
    Image

    Diaper rash cream

    I love using this for toddler especially because it helps soothes his skin keeping him rash free and when he has a rash it ittmedjally works I try using every time I see redness appearing helps him feel better and the residue afterwards you feel a lil bit but not much does its job easy to dipsense and easy to store anywhere.
    JenniferH
    Did you find this review helpful?
    5 out of 5 stars
    25 March, 2026
    originally posted on influenster.com
    Image

    A little goes a long way - protects and soothes sk

    I’ve been using this cream for a while and honestly. It works so well! It’s super gentle on the skin and perfect for daily use. I love that it helps prevent and soothe irritation right way. The texture is smooth and easy to apply, not too thick like other diaper creams. It creates a protected, thanks to the zinc oxide. I also like that it’s hypoallergenic and safe for sensitive skin, which gives me peace of minds
    AnaliiiiL
    Did you find this review helpful?
    5 out of 5 stars
    25 March, 2026
    originally posted on influenster.com
    Image

    Gentle, protective, and perfect for daily diaper c

    DESITIN® Daily Defense Cream is an essential for everyday diaper care. It creates a light, breathable barrier that helps protect your baby’s skin from moisture and irritation before diaper rash even begins. The formula is gentle, easy to apply, and doesn’t feel too thick or greasy. I love that it’s perfect for daily use and keeps my baby’s skin soft, smooth, and healthy. Definitely a trusted staple for parents!
    YimilaMaitteB
    Did you find this review helpful?
    5 out of 5 stars
    24 March, 2026
    originally posted on influenster.com
    Image

    Diaper rash fix!

    Desitin daily defense diaper rash cream comes in 2 oz tube. It’s #1 pediatricians recommended. I use it on my grandson everytime he gets a diaper rash and it works really well. It’s very affordable. You can find it and all most all stores.
    SusanS
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    21 March, 2026
    originally posted on influenster.com
    Image

    A gentle diaper cream with a smooth texture, soft

    I really pay attention to texture, ingredients, and how a product feels on my baby’s skin. Desitin Daily Defense has a smooth, creamy texture that spreads easily and creates a protective layer without feeling too heavy. It has a soft, clean scent that isn’t overwhelming, which I appreciate for daily use. I also like that the zinc oxide helps protect and soothe delicate skin. It absorbs well while still leaving that protective barrier, and it’s definitely a product I would keep using and recommending to other moms.
    LisneyVanessaF
    Did you find this review helpful?
    5 out of 5 stars
    15 March, 2026
    originally posted on influenster.com
    Image

    Good

    This baby cream si very good It helps keep my baby skin dry and moisturized i Love the texture the cream lasts me quite a While I like ist smell and fragance the packaging is very pratical
    DanielaM
    Did you find this review helpful?
    5 out of 5 stars
    9 March, 2026
    originally posted on influenster.com
    Image

    Great daily protection for sensitive baby skin.

    Great cream for everyday protection. It helps keep my baby’s skin healthy and prevents irritation before it starts. The scent is mild and not overpowering which I really appreciate for a baby product. The packaging is also convenient and easy to use. I recommend it.
    NataliiaK
    Did you find this review helpful?
    5 out of 5 stars
    6 March, 2026
    originally posted on influenster.com
    Image

    Buy it

    This cream has really been my salvation since my baby is very sensitive and helps him whenever he has any irritation I love it because everything it says in his box is effective and its texture is perfect because it leaves no residue
    EliannisV
    Did you find this review helpful?
    5 out of 5 stars
    6 March, 2026
    originally posted on influenster.com
    Image

    I love this Cream

    I have two babies and I love this Cream It’s The Only one i’ve used Because i love the smell and it heals súper fast my baby starts healing as soon as i apply it i love this Cream
    MaríaU
    Did you find this review helpful?
    5 out of 5 stars
    5 March, 2026
    originally posted on influenster.com
    Image

    Time tested. Time trusted

    A trusted brand that’s been around for decades. Used for my kids, my grandkids and will probably be using for my great grandkids and it’s not just for kids. I’ve used it on adults too.
    ESueS
    Did you find this review helpful?

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