Target New ArrivalsHalloweenClothing, Shoes & AccessoriesHome & DecorKitchen & DiningPatio, Lawn & GardenGroceryHousehold EssentialsBabyBeautyTarget Beauty StudioPersonal CareSports & OutdoorsPetsHealthWellnessSchool & Office SuppliesToys & GamesElectronics & TechVideo GamesBooks, Music & MoviesParty SuppliesGift IdeasGift CardsShop by CommunityTarget OpticalDealsClearanceNew ArrivalsBack to SchoolCollegeTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Aspercreme Lidocaine with No Mess Applicator - 2.5 fl oz - 2 of 4Aspercreme Lidocaine with No Mess Applicator - 2.5 fl oz - 3 of 4Aspercreme Lidocaine with No Mess Applicator - 2.5 fl oz - 4 of 4
Aspercreme Lidocaine with No Mess Applicator - 2.5 fl oz - 1 of 4

Aspercreme Lidocaine with No Mess Applicator - 2.5 fl oz

9 Questions
$8.99

In Stock

Eligible for registries and wish lists
Save 5% every day
With Target Circle™ Card (restrictions apply)

At a glance

About this item

Highlights

  • Contains one (1) 2.5-oz. roll-on bottle of Aspercreme Lidocaine Pain Relief Liquid With No-Mess Roll-On Applicator
  • Fast-Acting Relief: Max-strength 4% lidocaine topical numbing liquid targets nerves, numbs away pain and lasts
  • No-Mess Application: Convenient roll-on applicator offers targeted relief and keeps hands clean
  • Non-greasy Formula: Fragrance-free Aspercreme doesn't leave behind greasy residue or strong odor
  • Maximum-Strength Lidocaine: OTC Aspercreme offers the maximum-strength lidocaine pain relief available without a prescription and is FSA/HSA eligible
  • Travel-Size: Take your pain relief solution on the go in a compact and portable bottle
  • Aspercreme is the #1 topical lidocaine brand in the U.S.*

Description

Experience fast and long-lasting relief with Aspercreme Lidocaine Pain Relief Roll-On. This non-irritating topical analgesic numbs away pain with targeted precision. OTC Aspercreme pain relief liquid contains 4% lidocaine, the maximum allowed without a prescription. The non-greasy, fragrance-free formula with moisturizing aloe applies without greasy residue or odor. Aspercreme’s convenient no-mess roll-on applicator keeps hands clean while you apply it to your arm, back, foot, hand, leg or neck. Compact and travel friendly, it's the perfect pain-relief solution after a workout or on the go. Say goodbye to minor pain with Aspercreme, the No. 1 topical lidocaine brand in the U.S.* *Among OTC topical analgesics
Trial/Mini/Travel Size: Yes
Suggested Age: 12 Years and Up
Product Warning: Keep out of reach of children, consult a doctor if you are pregnant or nursing
Product Form: Roll On
Package Quantity: 1
Features: Nongreasy
Battery: No Battery Used
TCIN: 51447862
UPC: 041167058107
Item Number (DPCI): 245-07-0565
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

lidocaine hci 4%.

Purpose

Topical Anesthetic..

When using this product

When using this product : Use only as directed. Read and follow all directions and warnings on this carton,Do not allow contact with eyes and mucus membranes,Do not bandage or apply local heat (such as heating pads) or a medicated patch to the area of use,Do not use at the same time as other topical analgesics.

Stop use and ask a doctor if

Stop use and ask a doctor if : Condition worsens,Redness is present,Irritation develops,Symptoms persist for more than 7 days or clear up and occur again within a few days.

Flammable

Flammable: Keep away from fire or flame.

Adults and Children Over 12 Years

Apply a thin layer to affected area every 6 to 8 hours, not to exceed 3 applications in a 24 hour period.

Children 12 Years or Younger

Ask a doctor.

Inactive ingredients

acrylates/c10-30 alkyl acrylate crosspolymer, alcohol denat. (15%), aloe barbadensis leaf juice, aminomethyl propanol, c30-45 alkyl cetearyl dimethicone crosspolymer, caprylyl methicone, cetearyl alcohol, ceteth-20 phosphate, dicetyl phosphate, dimethicone, disodium edta, ethylhexylglycerin, glyceryl stearate, hydroxyethyl acrylate/sodium acryloydimethyl taurate copolymer, isohexadecane, methylparaben, polysorbate 60, steareth-2, steareth-21, water

Shipping details

Estimated ship dimensions: 1.73 inches length x 3.08 inches width x 5.87 inches height
Estimated ship weight: 0.27 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: Is this effective on mosquito bites?

submitted by ScapeXplorer - 6 months ago

  • A: Thank you for your inquiry. Please use the Aspercreme Lidocaine with No Mess Applicator as directed on the drug facts label. This product is indicated for temporary relief of pain, including insect bites. Do not use on wounds or on irritated or damaged skin.

    submitted byAspercreme - 6 months ago
    Brand expert

  • A: Thank you for your inquiry. Please use the Aspercreme Lidocaine with No Mess Applicator as directed on the drug facts label. This product is indicated for temporary relief of pain, including insect bites. Do not use on wounds or on irritated or damaged skin.

    submitted byMarket Performance Group - 6 months ago
    Brand expert

Q: Can I apply this before my ingrown toenail removal? I have to get injected with anesthetic and I'm scared of needles and I don't want to feel the pain of the needle to numb my toenail.

submitted by Pris - 10 months ago

  • A: Thank you for your inquiry. Aspercreme Lidocaine with No Mess Applicator is for external use only and is intended for temporary relief of pain. Do not use on wounds or on irritated or damaged skin. Please discuss with your healthcare professional if this is suitable to use in this case.

    submitted byAspercreme - 10 months ago
    Brand expert

  • A: Thank you for your inquiry. Aspercreme Lidocaine with No Mess Applicator is for external use only and is intended for temporary relief of pain. Do not use on wounds or on irritated or damaged skin. Please discuss with your healthcare professional if this is suitable to use in this case.

    submitted byMarket Performance Group - 10 months ago
    Brand expert

Q: After checking the ingredients, I just want to make sure this has no menthol. Thank you :)

submitted by tnt - 1 year ago

  • A: Thank you for your inquiry. While Aspercreme with Lidocaine No Mess Applicator is not formulated with menthol, this product is processed in a facility that also processes menthol. If you are asking due to an allergy or sensitivity to menthol, please note this product is not specifically tested to confirm the total absence of menthol.

    submitted byAspercreme - 1 year ago
    Brand expert

  • A: Thank you for your inquiry. While Aspercreme with Lidocaine No Mess Applicator is not formulated with menthol, this product is processed in a facility that also processes menthol. If you are asking due to an allergy or sensitivity to menthol, please note this product is not specifically tested to confirm the total absence of menthol.

    submitted byMarket Performance Group - 1 year ago
    Brand expert

Q: Can I use this before getting a tattoo?

submitted by s - 1 year ago

  • A: Thank you for your inquiry. No, you should not use Aspercreme Lidocaine with No Mess Applicator for numbing purposes before a tattoo, as this is an off-label use. The product should only be used to temporarily relieve minor pain after the pain presents itself, and the product is not permitted to be used on a preventative basis in this manner. Do not use in large quantities or on irritated or damaged skin. Please use Aspercreme Lidocaine with No Mess Applicator as directed on the drug facts label and consult with your healthcare professionals for additional guidance.

    submitted byAspercreme - 1 year ago
    Brand expert

  • A: Thank you for your inquiry. No, you should not use Aspercreme Lidocaine with No Mess Applicator for numbing purposes before a tattoo, as this is an off-label use. The product should only be used to temporarily relieve minor pain after the pain presents itself, and the product is not permitted to be used on a preventative basis in this manner. Do not use in large quantities or on irritated or damaged skin. Please use Aspercreme Lidocaine with No Mess Applicator as directed on the drug facts label and consult with your healthcare professionals for additional guidance.

    submitted byMarket Performance Group - 1 year ago
    Brand expert

Q: How long does it take to work

submitted by Luffy - 5 years ago

  • A: All consumers may feel the effects of the product at different levels and/or duration of time. We do not have any further information regarding the time of onset of action.

    submitted byMarket Performance Group - 5 years ago
    Brand expert

Q: Does this work for laser hair removal? It’s painful and I am looking for a cream that can numb the area before the treatment but I don’t want it to have secondary effects. Hope to get an answer soon

submitted by Laser hair removal - 5 years ago

  • A: Sanofi does not have any information on the use of Aspercreme with Lidocaine No Mess Applicator before or after laser hair removal. Sanofi recommends speaking to your healthcare provider to determine if Aspercreme with Lidocaine No Mess Applicator is appropriate for you.

    submitted byMarket Performance Group - 5 years ago
    Brand expert

Q: Why does it only work on some spots? I put it on my hand/wrist and it numbed my hand/wrist but when I put it on my forearm, it didn’t numb anything.

submitted by AB - 6 years ago

  • A: The duration of the effect can vary by individual, the area being treated, and the amount of product applied. Please reach out to your healthcare provider if you have any additional questions or concerns.

    submitted byMarket Performance Group - 5 years ago
    Brand expert

Q: Does this work on neurological pain?

submitted by Jo - 6 years ago

  • A: Sanofi does not have any evidence to support the use of Aspercreme with Lidocaine No Mess Applicator for neurological pain. Sanofi recommends speaking to your healthcare provide to determine if Aspercreme with Lidocaine No Mess Applicator is appropriate for you.

    submitted bySanofi - 6 years ago

Q: Can this be used before facial threading and waxing to relieve pain?

submitted by Debby - 7 years ago

  • A: We have not tested this product for preventative facial threading and waxing pain relief, therefore we cannot recommend using this product in that manner. Please refer to the labeling instructions for intended usage and instructions.

    submitted bySanofi - 7 years ago
See all questions (9)

Additional product information and recommendations

Discover more options

Skip to next section

Frequently bought together

Skip to next section

Guests also viewed

Skip to next section
4.4 out of 5 stars with 565 reviews
quality: 3.94 out of 5
value: 3.8 out of 5
72% would recommend
59 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
18 September, 2026Verified purchase

Love this roll on applicator

This is the best. I can apply it myself without any help. Takes away the pain almost instantly.
Nicole
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
16 September, 2026
originally posted on influenster.com
Image

Best application !

This is my favorite way to apply aspercreme! The no-mess rollerball application is amazing. I love being able to put it on my lower back by myself without getting my hands covered in numbing cream.
RyleeK
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
12 September, 2026Verified purchase

Aspercreme

I found this roll-0n works for me. If you don't like a strong scent, this is the one for you. Love it.
June
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
7 September, 2026

Works great!

Daughter has some unexplained (what appears to be) nerve pain, as well as her being an athlete. It took both pains away- nerve and muscular. It also applies really cleanly.
JosieGrossie
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
1 out of 5 stars
25 August, 2026
originally posted on aspercreme.com

Cannot get the cap off.

IMPOSSIBLE to get the cap off! Packaging was obviously designed by someone under age 30. My husband, myself and a pair of pliers working together could not get this cap off. Do they realize people with arthritis purchase this?
1 reply from Opella Consumer Care team - 26 days ago
We’re sorry to hear that your experience wasn’t what you hoped. We’d really like to learn more and see how we can help. Give us a call at 866-844-2798, option 1, or reach out to us here: https://www.opella.com/our-countries/en-us.
minday09
Did you find this review helpful?
1 out of 5 stars
7 July, 2026
originally posted on aspercreme.com

Nothing after applied

I don't feel anything going on (numbness expected)
1 reply from Opella Consumer Care team - 3 months ago
We’re sorry to hear that your experience wasn’t what you hoped. We’d really like to learn more and see how we can help. Give us a call at 866-844-2798, option 1, or reach out to us here: https://www.opella.com/our-countries/en-us.
Still in pain in NC
1 guest found this review helpful. Did you?
2 out of 5 stars
Thumbs down graphic, would not recommend
13 June, 2026Verified purchase

CANNOT GET THE CAP OFF!!!

I am having to return this because no matter how hard I squeeze on those tabs, it will not budge. Maybe dynamite or a jack saw would help, but I don’t have any on hand. This is really disappointing and frustrating.
Pepper
Did you find this review helpful?
5 out of 5 stars
11 June, 2026
originally posted on influenster.com
Image

Great pain relief!

I am a busy nurse who is on her feet all day. My body aches after a 12 hour shift. This is super easy to apply and is not scented which helps since I work at the hospital. I notice immediate pain relief!
ChrisL
2 guests found this review helpful. Did you?
5 out of 5 stars
11 June, 2026
originally posted on influenster.com
Image

Great pain relief!

I have a lot of bone and muscle pain as I am on my feet for 14 hours at least a day. This had been a life saver and instantly relieves my pain. There is not an odor which helps as I work in a hospital. Great product!
JoannB
2 guests found this review helpful. Did you?
2 out of 5 stars
10 June, 2026
originally posted on aspercreme.com

Cannot open cap

Well, I don't know if the product is any good because I cannot open the cap. What in the world makes people think someone who needs this product is going to have the strength to open the cap.
1 reply from Opella Consumer Care team - 4 months ago
Thank you for sharing your feedback. We’re sorry to hear about your experience and would love the opportunity to assist you. Please reach out to us at 866-844-2798, option 1, or visit this link to contact us: https://www.opella.com/our-countries/en-us.
Old gal
Did you find this review helpful?
5 out of 5 stars
18 April, 2026
originally posted on influenster.com
Image

Must have for pain!

Amazing!! I always have in my golf bag, absolute must!! The versatility of roller is great and easy to apply wherever the pan is! The texture is nice and smooth and absorbs super quick!!
JessicaS
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
5 April, 2026Verified purchase

(no review title)

Work good to help with back pain and rubs on easily
Abby
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
2 out of 5 stars
3 April, 2026
originally posted on aspercreme.com

Pain in the butt

Could you make the cap harder to remove? If so, I would skip the channel lock pliers and go right to the vise in my workshop to make it easier on my arthritic hands.
Rick
2 guests found this review helpful. Did you?
4 out of 5 stars
10 March, 2026
originally posted on influenster.com
Image

It's always kept on hand.

Having active children keeping this in our bag is amazing. With the soothing ingredients it helps ease their aches. With the easy application its great for making no mess.
JamieF
1 guest found this review helpful. Did you?
5 out of 5 stars
5 March, 2026
originally posted on influenster.com
Image

Great product

Easy to apply with mess free application. Super effective when applied directly to the area that needs attention. Long lasting relief. Does not stain your clothes or smell bad.
JennB
2 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
2 March, 2026Verified purchase

Roll on reliever!

Great product. Does exactly what it advertises. Eases pain, non greasy, fast acting....etc. Love the convenience and easiness of a roll on. No mess and works great!
Bretsmom
quality: 5 out of 5
value: 5 out of 5
2 guests found this review helpful. Did you?
5 out of 5 stars
12 February, 2026
originally posted on influenster.com
Image

Easy no-mess-roll-on that provides fast, long-last

The roll- on applicator makes it easy to apply without getting product on my hands, which I really like. It provides a cooling sensation at first and then helps numb the pain within minutes. I use it on my back, shoulders, and knees after long workdays, and the relief lasts for several hours. It’s lightweight, dries quickly,and doesn’t leave a strong smell. Great option for quick, mess- free pain relief on the go.
danielac1038_1679
1 guest found this review helpful. Did you?
5 out of 5 stars
28 January, 2026
originally posted on influenster.com
Image

Affordable Relief

This works! It's not perfect and doesn't take away all of the pain but it's effective for lessening much of it. I bought the one in a lotion type form and I feel it works a little better. Maybe that is because I rub it in more with my fingers. It's the same brand. I am pleased with this. This is my go to roll on pain reliver and it doesn't even come close to leaving a mess, it only take a minute or two and I can fell it working, and keeps on working for hours.
duyd88_9384
1 guest found this review helpful. Did you?
5 out of 5 stars
6 December, 2025
originally posted on influenster.com
Image

No mess instant relief

Aspercreme Lidocaine No-Mess has become a staple in our house. The applicator is exactly what it says — no mess, no sticky hands, no strong medicine smell. You just roll it on and within minutes that numbing relief kicks in. It’s perfect for sore muscles, tight shoulders, lower-back pain, or those random aches that show up out of nowhere.
angelac72a2_7020
1 guest found this review helpful. Did you?
5 out of 5 stars
25 November, 2025
originally posted on influenster.com
Image

Easy application

Way application especially on the back areas that are harder to reach. Leaves no residue and absorption is quick providing instant relief. Not too strong smelling.
prathap2_4883
Did you find this review helpful?

Get top deals, latest trends, and more.

Privacy policy
Terms