Differin Adapalene Gel 0.1% Acne Treatment - 15g

Differin Adapalene Gel 0.1% Acne Treatment - 15g - image 1 of 4Differin Adapalene Gel 0.1% Acne Treatment - 15g - image 2 of 4Differin Adapalene Gel 0.1% Acne Treatment - 15g - image 3 of 4Differin Adapalene Gel 0.1% Acne Treatment - 15g - image 4 of 4
Differin Adapalene Gel 0.1% Acne Treatment - 15g - image 1 of 4
$14.99When purchased online

About this item

At a glance

No Synthetic Fragrance
No Synthetic Fragrance
HSA/FSA Eligible
HSA/FSA Eligible
Oily Skin
Oily Skin
Dermatologist Tested
Dermatologist Tested
Combination Skin
Combination Skin
Acne-Prone Skin
Acne-Prone Skin

Highlights

  • Clear and prevent acne with an Rx-strength retinoid
  • Fights the main causes of acne by regulating skin cell turnover & reducing inflammation deep in the skin to clear and prevent pimples, blackheads and clogged pores
  • Differin Gel can reduce up to 87% of acne in just 12 weeks (Cunliffe et al 1998, Galderma Laboratories)
  • Effectively treats acne to restore your skin's natural tone & texture
  • The retinoid in Differin heals current acne and stops new acne from forming

Specifications

Scent: Unscented

Health Facts: Dye-Free, Contains Retinoids, Phthalate-Free, Aluminum-Free, No Fragrance Added

Product Form: Gel

Beauty Purpose: Spot Treatment

Recommended Skin Type: Oily, Acne-Prone, Combination

Net weight: 15 Grams

Features: Dermatologist Recommended, Dermatologist Tested

TCIN: 51346324
UPC: 302994920303
Item Number (DPCI): 037-12-0197
Origin: Assem USA w/foreign/dom. parts
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.

Description

Unlike other acne treatments you can buy in stores, Differin contains the first OTC Rx-strength acne-fighting retinoid. Retinoids play a crucial role in the treatment of acne by regulating skin cell turnover & reducing inflammation deep in the skin to clear & prevent pimples. What makes the retinoid in Differin (Adapalene) so cool is that, unlike other topical prescription retinoids, Differin is gentler on your skin, while still effective — and you don’t have to do things like completely avoid sunlight forever!

Then apply a thin layer of Differin Gel once every day all over your face — even when you’re not breaking out. Differin Gel might take a few weeks to start to work, and during this time, you could experience some dryness and irritation while your skin gets ready for gorgeous. The retinoid in Differin Gel may take a few weeks to work, and it may seem like it’s getting a little worse before it gets better. But, like your old track coach used to say, “You just gotta push through it!”

When used every single day, Differin Gel can reduce up to 87% of acne in just 12 weeks. That’s about the time it would take to leisurely binge-watch your favorite old TV series.

No Synthetic Fragrance
A product that either makes an on-pack statement indicating that it does not contain synthetic fragrance, or carries an unqualified on-pack statement "no fragrance".
HSA/FSA Eligible
Restrictions apply; contact your insurance provider about plan allowances and requirements
Oily Skin
Recommended for Oily Skin.
Dermatologist Tested
Dermatologist tested product.
Combination Skin
Recommended for Combination Skin.
Acne-Prone Skin
Recommended for Acne-Prone Skin.
See how we make shopping for wellness even easier.
If the item details above aren’t accurate or complete, we want to know about it.

Active ingredients

adapalene (retinoid)* 0.1%

Purpose

Acne treatment

Uses

Use For the treatment of acne

Directions

Directions Adults and children 12 years of age and older: use once daily clean the skin gently and pat dry before applying the product cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. do not use more than one time a day. Applying more than directed will not provide faster or better results, but may worsen skin irritation. Children under 12 years of age: ask a doctor

Other information

Other information store at room temperature 68°-77°F protect from freezing

Inactive ingredients

carbomer 940, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water and sodium hydroxide. may contain hydrochloric acid to adjust ph.

Shipping details

Estimated ship dimensions: 6.4 inches length x 2.7 inches width x 1.93 inches height
Estimated ship weight: 0.08 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup. If purchased online with SNAP EBT, this item must be returned within 90 days of the date it was shipped, delivered by a Shipt shopper, or made ready for pickup. This 90-day return window is required by SNAP.
See the return policy for complete information.

Q: Can this be mixed with niacinamide or benzoyl peroxide?

submitted by - 2 years ago
  • A: While tretinoin is unstable and cannot be used with benzoyl peroxide, adapalene is stable and can be used with benzoyl peroxide. A combination medication is actually available by prescription (Epiduo). While they can be combined, sometimes benzoyl peroxide is too irritating when used with Differin. Because benzoyl peroxide can bleach pillowcases, some people apply Differin at night and benzoyl peroxide in the mornings. Benzoyl peroxide is available in different strengths, so ask your physician or start with one of the lower concentrations to reduce the chances of irritation.

    submitted byAnonymous - 2 years ago
  • A: I was told by my dermatologist that benzoyl peroxide and retinoids basically cancel each other out.

    submitted byIlovetarget - 2 years ago
  • A: Hi @tropical. Thanks for your question. Generally we do not recommend mixing Differin Gel with other active ingredients, however we would recommend checking in with your dermatologist who can provide guidance for your unique skin! Hope this helps. Thanks

    submitted byGalderma Team Member - 2 years ago
    Brand expert

Q: I currently use a salicylic acid cleanser, benzoyl peroxide gel (5%), and a moisturizer day and night for light/moderate acne. How do I add this to my current routine?

submitted by tmg - 5 years ago
  • A: I agree with the other responses, and I'd like to add that if you're currently using AHA or BHA or benzyl peroxide products currently, give your skin a break for about a week before using any retinoid product such as Differin. And I would also not recommend using any other chemical or physical exfoliant products while you use a retinoid if you have sensitive skin, otherwise you run the risk of burning your skin or really irritating it and causing redness.

    submitted byavkayes - 2 years ago
  • A: According to the manufacturer of this drug they do not recommend that you use any type of other active ingredients that contain AHA or BHA or Glycolic acids while using Differn Gel. In my opinion, I would let your skin acclimate to Differn for at least 2-3 months and maybe do a few test patches with your favorite products before jumping in full throttle. I can sympathize with you, I just started Differn 2 weeks ago and I hated to give up my favorite gylcolic acid toner and BHA serum, but so far I am seeing far superior results with Differn alone on my stubborn blackheads that have pestered me since my teens and I’m in my mid 40’s. My complexion is also improving in tone and texture as well. Hope this helps!

    submitted byBeachbride322 - 4 years ago
  • A: Hi, tmg. Differin Gel is more than just a spot treatment so we recommend applying this product daily to stop new acne from forming.To limit skin irritation or flakiness, try switching to hydrating cleansers every other day to keep skin moisturized during treatment. Hope this helps!

    submitted byTarget Beauty Concierge - 5 years ago
    Brand expert

Q: Would this work as a spot treatment?

submitted by bb1342 - 2 years ago
  • A: Actually, retinoids are not to be used as spot treatments. They take time to work and are most effective when consistently used over periods of time. More appropriate spot treatments would be benzoyl peroxide or salicylic acid.

    submitted byAnonymous - 2 years ago
  • A: Hi bb1342! This is a fantastic spot treatment. Hope this helps!

    submitted byTarget Beauty Concierge - 2 years ago
    Brand expert

Q: is this good for normal to dry sensitive skin?

submitted by Briana - 2 years ago
  • A: Differin OTC is the lowest concentration available, and Differin is considered to be the gentlest retinoid. A cream version is available by prescription that some people find more suitable for dry skin. You could also try layering Differin with a gentle moisturizer, whether under or over the Differin. It may be a matter of trial and error.

    submitted byAnonymous - 2 years ago
  • A: Hi Briana! This Acne Treatment works well with all skin types, including dry, sensitive skin types! Adapalene is a gentle acne treatment. Hope this is helpful!

    submitted byTarget Beauty Concierge - 2 years ago
    Brand expert

Q: What comes in the container because I think something is missing out of it?

submitted by Keya - 4 years ago
  • A: the box is weird, it looks likes something is missing because of all the extra space inside, but its just the bottle, its not missing anything...

    submitted bygoodkine - 2 years ago
  • A: Hi Keya! This will contain a 15mg tube of the Different Acne Treatment Gel. Hope this helps!

    submitted byTarget Beauty Concierge - 4 years ago
    Brand expert

Q: Does this help teens also or only adults

submitted by I need help acne - 5 years ago
  • A: Hi there. Differin Gel has been approved for anyone 12 years and older with mild to moderate acne. If you have severe acne, we recommend speaking with your doctor before using. Hope this helps!

    submitted byTarget Beauty Concierge - 5 years ago
    Brand expert
  • A: I would certainly give this a go before going to see a dermatologist for your teen. Chances are it will help improve the acne, and if it doesn't, you're only out $14 and your teen's skin will have ready had time to acclimate to using prescription strength retioniods. Retin A/ Tretinoin is much stronger and the side effects are brutal in the beginning, some people give up because of the peeling and irritation.

    submitted byBeachbride322 - 4 years ago

Q: Although I have an occasional pimple, acne is not a main concern of mine. I have dark spots from sun damage... will this product help if I apply vitamin C serum over it?

submitted by artful - 5 years ago
  • A: I'm in my mid 40’s and have the same issues with my skin as you but add a million blackheads to it and so far, I am loving the results! Just after two weeks my blackheads and whiteheads are disappearing rapidly, sunspots are fading, and the all over improvement of texture is unbelievable! I will continue using for at least 6 more months before I make a decision on whether or not it is effective on deeper wrinkles, as these medications take time to see full results. But so far, I am blown away!

    submitted byBeachbride322 - 4 years ago
  • A: Hi, Artful. This product is a prescription strength acne medication that specifically targets pimples, blackheads, and whiteheads. Since your main concern is dark spots, we recommend opting for a serum that contains retinol, which will improve skin texture and fade dark spots over time. Hope this helps!

    submitted byTarget Beauty Concierge - 5 years ago
    Brand expert

Q: Does this also help with black spots on your face due from acne?

submitted by Lala - 6 years ago
  • A: If you're speaking of blackheads, yes! I have had very stubborn blackheads that completely cover my nose, chin and a some scattered throughout my cheeks. I also have whiteheads that nothing else works on. This is a miracle product on blackheads! Only 2.5 weeks since initial application and I can see a visible difference. They are finally giving way little by little and are waaay less visible!

    submitted byBeachbride322 - 4 years ago
  • A: Yes, the active ingredient in Differin also targets dark spots and scars left behind from acne (post-inflammatory hyperpigmentation).

    submitted byskingenie - 6 years ago

Q: Can anyone tell me if this is vegan? Thank you.

submitted by JudyBeauty - 12 days ago
  • A: Hello Judy, the Differin Adapalene Gel 0.1% Acne Treatment is considered vegan but is dye-Free, contains Retinoids, Phthalate-Free, Aluminum-Free, and has no fragrance added. For all your future beauty questions, get real-time answers using the “Chat with a Virtual Beauty Consultant” button, found on every product page :)

    submitted byTarget Beauty Consulting - 12 days ago
    Brand expert

Q: can Organic Jojoba Oil balancing face oil for oil skin types be used as a moisturizer when using the Differin Adapalene Gel 0.1% acne treatment 15g?

submitted by DJ - 11 months ago
  • A: Hello DJ! If you have oily skin, try using it every other day or mix it in with your favorite Differin moisturizer to avoid overdrying.

    submitted byTarget Beauty Consulting - 11 months ago
    Brand expert
4.7 out of 5 stars with 2805 reviews
90% would recommend
243 recommendations
Treats Spots: 4.91 out of 5
Improves Skin Texture: 4.85 out of 5
Accurate Scent: 4.77 out of 5

Works Great!

5 out of 5 stars
Would recommend
AutumnDee - 9 days ago, Verified purchaser
I’ve been using this product for the past 2 weeks and the difference in my skin is night and day. My pimples are almost fully gone and I have no more protruding bumps! I use this along with the Differin dark spot correcting serum and the results have been fantastic! It’s become apart of my nightly skin care routine!
Accurate Scent: 3 out of 5
Treats Spots: 5 out of 5
Improves Skin Texture: 5 out of 5
1 guest found this review helpful. Did you?

Works but requires PATIENCE

5 out of 5 stars
Would recommend
Bees - 10 days ago, Verified purchaser
This works but you have to be patient. It takes at least a few weeks, it took several for me, and you need to put it on your whole face, not just where you have a breakout. I’m on week 10, I normally break out horribly before my period, but last month I only had one pimple. This also helped clear a couple really deep stubborn blackheads. I’ve used retin-a before, which works faster but also made me super peel-y and dry. This works a lot slower but is much gentler on your skin. Combining it with niacinamide and vitamin c products has finally made a difference with old acne scars and texture too, though maybe not quite as much as I had hoped. I might need to see an esthetician for more dramatic results with that. But my breakouts are pretty much totally under control now. Just give it time to work and do it’s thing and you’ll be pleasantly surprised.
Treats Spots: 5 out of 5
Accurate Scent: 5 out of 5
Improves Skin Texture: 4 out of 5
2 guests found this review helpful. Did you?

It's a miracle!

5 out of 5 stars
Avda - 13 days ago
originally posted on differin.com
Been using the gel 5 months. Suffered from adult painful cystic acne. After 1 month of nightly use 50% improvement, after 2 month 75% improvement, after 3 months 100% clear skin. I now use it every other night because it has also made the texture of my skin smooth as a baby's behind & the pores on my nose & face are a lot smaller. If I feel even one cyst starting I go back to every night application until it is gone. If you suffer from acne make the 3 month commitment to try it & don't give up!
3 guests found this review helpful. Did you?

Works great

5 out of 5 stars
Would recommend
Hina - 14 days ago, Verified purchaser
This stuff is effective for my oily skin and this really helps clear up my pimples & tiny bumps and it has now become a daily part of my sensitive skin routine. Definitely worth buying
Treats Spots: 5 out of 5
1 guest found this review helpful. Did you?

One of the best over the counter

4 out of 5 stars
laurenm623 - 17 days ago
originally posted on influenster.com
This is one of the best over the counter treatments. I have hormonal acne and this helped. It does dry out your skin so make sure you moisturize it.
Did you find this review helpful?

Good

4 out of 5 stars
avag74 - 27 days ago
originally posted on influenster.com
Just started using this and on the first day I already notice a change to my acne. I’m hoping to use this more and I’m looking forward to clearing my skin up
Did you find this review helpful?

Game changer

5 out of 5 stars
sommerr4 - 29 days ago
originally posted on influenster.com
This helped cleared my complexion within two months! I am super happy with the results it gave me, & this is going to become a staple in my skincare routine from now on. Give this a try!
3 guests found this review helpful. Did you?

I feel like my

5 out of 5 stars
sarahchungmalmstrom - 1 month ago
originally posted on influenster.com
I feel like my skin is improved the morning after using it the previous night. I use a pea sized amount about twice a week, and I love that it helps with anti aging as well as my minor acne that pop up now and again. One tube lasts a long time and it spreads well also.
7 guests found this review helpful. Did you?

holy grail acne product

5 out of 5 stars
Would recommend
candacel97 - 1 month ago, Verified purchaser
I never write reviews but this stuff is amazing! i was using tretinoin and my skin was just getting worse, but after using differin two nights in a row i now have almost clear skin. (one or two left that are still under the skin) get it!!!
Improves Skin Texture: 5 out of 5
Accurate Scent: 5 out of 5
Treats Spots: 5 out of 5
10 guests found this review helpful. Did you?

Differin Combo

5 out of 5 stars
vickyg46 - 1 month ago
originally posted on influenster.com
I use the Differin daily refreshing cleanser and then apply my Differin gel. I use a light moisturizer and this combo keeps breakouts minimal. I used to have to buy a membership to an expensive brand and I’m so thankful for Differins price and availability.
4 guests found this review helpful. Did you?

The best for stubborn acne

5 out of 5 stars
ashtonk2 - 2 months ago
originally posted on influenster.com
I love this product. It can be harsh. Definitely not for sensitive skin. Beats acne the best, even back acne. I highly recommend for anyone with recurring acne. Any Differin product rocks
7 guests found this review helpful. Did you?

Get it !

5 out of 5 stars
Would recommend
emmc - 2 months ago, Verified purchaser
If you have mild acne this is the stuff ! But ask a docotor if your skin is sensitive
Improves Skin Texture: 5 out of 5
Accurate Scent: 5 out of 5
Treats Spots: 5 out of 5
6 guests found this review helpful. Did you?

Love

5 out of 5 stars
brandim105 - 2 months ago
originally posted on influenster.com
This differin gel is nothing short of Amazing when it comes to clearing acne. I have very sensitive oily skin and tend to get hormonal acne with occasional cystic acne. When I feel a pimple coming on I put some of the gel on it before bed and by morning it is already going away. This gel has saved me from actually getting a “pimple pimple” in over a year since I stumbled upon it. It has also helped my teenagers tame their breakouts. Fragrance free. Would repurchase
7 guests found this review helpful. Did you?

Worked Better for My Acne than Tretinoin!

5 out of 5 stars
Would recommend
MissBanksy - 2 months ago, Verified purchaser
I love Tretinoin for anti-aging benefits but Differin Gel was what cleared up my acne. This stuff is AMAZING. Like, I'm shook lol. My skin is super accustomed to strong products so I didn't experience the side effects some folks did (dryness, etc). I do feel it "working" but it's not uncomfortable as long as I exfoliate, tone (alcohol-free), drink lots of water, and moisturize well day and night. I'm pretty shocked how well it worked - my skin looks incredible.
Accurate Scent: 5 out of 5
Treats Spots: 5 out of 5
Improves Skin Texture: 4 out of 5
8 guests found this review helpful. Did you?

Acne under control

5 out of 5 stars
Would recommend
Grace - 2 months ago, Verified purchaser
Works if you use it consistently but I notice an improvement first day
Improves Skin Texture: 5 out of 5
Accurate Scent: 5 out of 5
Treats Spots: 5 out of 5
2 guests found this review helpful. Did you?

Good stuff

5 out of 5 stars
- 2 months ago
originally posted on influenster.com
Our family swears by Differin. Once our oldest saw a dermatologist to get his acne under control with lots of medications, we were able to use this instead. My daughter is now going through pop up acne and loves how quickly it works.
2 guests found this review helpful. Did you?

I love this product

5 out of 5 stars
yens5 - 2 months ago
originally posted on influenster.com
I have been using this product, this is the 2nd tube that I’m using now. I used the lot of stuff, they’re all expensive stuff but they didn’t help me with the acne. But DIFFERENT does help me a lot. My skin got a lot better now. I’m glad that I found it, I wish that I found it sooner.
1 guest found this review helpful. Did you?

love love

5 out of 5 stars
dizzyi - 2 months ago
originally posted on influenster.com
i use this once a day and only in the morning, i use it after i wash my face and put on my moisturizer. i love this product, but sometimes it gets sticky and doesnt dry out like it usually does.
1 guest found this review helpful. Did you?

Great Buy!

5 out of 5 stars
Would recommend
Star Commentor - 2 months ago, Verified purchaser
Helped my daughter get rid of most of her acne spots and marks. It does take time to work, so please DO NOT EXPECT OVERNIGHT RESULTS! I bought this a second time because of how well it worked the first time.
Accurate Scent: 5 out of 5
Treats Spots: 5 out of 5
Improves Skin Texture: 5 out of 5
8 guests found this review helpful. Did you?

This is one of

5 out of 5 stars
miar29 - 2 months ago
originally posted on influenster.com
This is one of the only things thats helped my hormonal acne, I tried a variety of different things and have very sensitive skin but this was my saving grace of a product.
7 guests found this review helpful. Did you?

Get top deals, latest trends, and more.

Privacy policy

Footer

About Us

About TargetCareersNews & BlogTarget BrandsBullseye ShopTarget's Coronavirus ResponseSustainability & ESGPress CenterAdvertise with UsInvestorsAffiliates & PartnersSuppliersTargetPlus

Help

Target HelpReturnsTrack OrdersRecallsContact UsFeedbackAccessibilitySecurity & FraudTeam Member Services

Stores

Find a StoreClinicPharmacyOpticalMore In-Store Services

Services

Target CircleRedCardTarget AppRegistrySame Day DeliveryOrder PickupDrive UpFree 2-Day ShippingShipping & DeliveryMore Services
PinterestFacebookInstagramTwitterYoutubeTiktokTermsCA Supply ChainPrivacyCA Privacy RightsDo Not Sell My Personal InformationInterest Based Ads