Max. Strength Acne Medication - 1oz - up&up™
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$5.89
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4.2 out of 5 stars with 1051 ratings
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4.1 out of 5 stars with 1451 ratings
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4.2 out of 5 stars with 879 ratings
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4.6 out of 5 stars with 4895 ratings
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Bestseller
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$4.99($0.06/count)
$4.49 with Target Circle
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Guests are saying
This acne treatment cream has garnered positive feedback for its effectiveness in clearing breakouts and improving skin texture. Many guests have reported significant improvements in their acne within days of use, making it a go-to solution for spot treatment. However, some guests have experienced dryness and irritation, suggesting that it may not be suitable for sensitive skin. Overall, it is praised for its affordability and potency, making it a valuable addition to any skincare routine.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.3 out of 5 stars with 2138 reviews
effectiveness: 4.13 out of 5
quality: 4.03 out of 5
value: 4.24 out of 5
76% would recommend
506 recommendations
1 out of 5 stars
13 March, 2026Verified purchase
Worst item I have ever purchased
DO NOT BUY!!! where ever you put it on your face. It will leave you with red irritated spots. I put it on my cheeks and I woke up the next morning with redness everywhere I put it on ! do not buy the generic brand buy the real thing!!!
1 out of 5 stars
Thumbs down graphic, would not recommend
27 February, 2026Verified purchase
NEVER AGAIN!
Like another commenter this and other different Target brand skincare products have made my eyes swell up and itch and cause severe reactions. Never buying target brand skincare again.
1 out of 5 stars
Thumbs down graphic, would not recommend
24 February, 2026Verified purchase
Horrible!
Bought this product for my acne and my skin broke out in a rash and swelled my eye shut!
3 out of 5 stars
21 February, 2026Verified purchase
(no review title)
It works but very strong makes my skin peal unfortunately but the pimple does get smaller price is a very cheap alternative for acne
5 out of 5 stars
Thumbs up graphic, would recommend
19 February, 2026Verified purchase
Great for acne
I’ve been using the green and white one before they released the new design and it lasted me geniunely forever and worked so well for my acne/my skin. I love the new design I’m so excited to use this.
4 out of 5 stars
Thumbs up graphic, would recommend
15 February, 2026
Awesome
Acne went away!
2 out of 5 stars
Thumbs down graphic, would not recommend
1 February, 2026
(no review title)
I used it for my face, but got a red rash after using it.
5 out of 5 stars
Thumbs up graphic, would recommend
30 January, 2026Verified purchase
Holy grail product!
I absolutely love this product!! A little goes a long way and it makes pimples disappear. Make sure to read the warnings on the back before you use. I only use it at night and it’s great. I started using smaller amounts until my skin got used to it.
5 out of 5 stars
Thumbs up graphic, would recommend
27 January, 2026Verified purchase
Clearing up my face!!
I was previously using PanOxyl face wash but I needed a cream vs a face wash and decided to give this a shot since it’s cheaper than PanOxyl. I have a problem with closed comedones and this little tube of magic has almost cleared them all up!! I don’t have super sensitive skin so I’m able to apply it 2-3x daily and just use beef tallow once a day to moisturize. This stuff has done more for me than my prescription acne medication from my dermatologist
1 out of 5 stars
Thumbs down graphic, would not recommend
22 January, 2026Verified purchase
Avoid at all costs!
This used to my holy grail solution for acne, but when I received a new shipment with the updated color and design, I was immediately disturbed by the change in smell- nevertheless, I used it as part of my regular skincare routine. Shortly after, I was going through what I thought was a bout of hormonal acne- I may have a few pimples during my luteal phase- but it lasted OVER A MONTH, with deep, scarring pimples that are unlike anything I’ve EVER had IN MY LIFE. New ones cropped up nearly every day. I stopped using this after realizing it wasn’t even helping like it usually would in this kind of acne situation over the last TEN YEARS that I have used it, and GASP! My acne cleared up in a couple days. My skin looks great with no new breakouts (even during my luteal & menstrual phase!) no thanks to this change in formula which has now resulted in pitted acne scars. Absolutely appalling! I should have known not to use it by the smell. Such a sad development. It literally smells like mildew and strong chemicals, and my skin is still recovering. Some of the pitting and hyperpigmentation looks like it will never go away :( I almost feel entitled to financial compensation, lol. PLEASE DON’T TRY THIS. Target, please go back to the old formula, this one is crap!
5 out of 5 stars
Thumbs up graphic, would recommend
18 January, 2026Verified purchase
Would buy again
I see many reviews saying how strong it is, and it is. I think I accidentally got it somewhere it wasn’t needed, and it became very itchy. However the four pimples I had three days ago are either gone completely, or became post acne marks already. To me, this is a win. Without any product, my pimples will last nearly a week before becoming a post acne mark. I think the takeaway for me is that it’s extremely effective, but also very strong, so I will proceed with caution.
1 out of 5 stars
Thumbs down graphic, would not recommend
16 January, 2026Verified purchase
Allergic reaction
Having used Clearsil invisible cream w 10% benzyl peroxide before, I tried this because they no lo ger make it. After use, the next day I noticed redness and tenderness on my face. It started to burn and it, and I couldn't take it anymore and washed it off. My eyes are still puffy and dry after 2 days. Terrible formulation.
1 out of 5 stars
14 January, 2026
New tube color is not the same formula
Really disappointed. I used this for years and raved about it, but the new purple tube is different. Smells different, feels different, does not work the same. I will be seeking out a different brand.
5 out of 5 stars
Thumbs up graphic, would recommend
11 January, 2026
Exactly what I was looking for
I needed some medication for acne and this product worked on my skin
5 out of 5 stars
Thumbs up graphic, would recommend
9 January, 2026Verified purchase
Backacne / cystic acne
I really like this for back acne and spot treatment !! It also affordable
5 out of 5 stars
Thumbs up graphic, would recommend
6 January, 2026Verified purchase
It Works - Others Cause Allergic Reactions
This works very well with my skin. I have a dialated pore on my forehead and when I pick at it, sometimes it flares up and cases acne. This knocks it right out! I recently tried another brand that had the same ingredients listed, but that brand caused an allergic reaction for me, while this one has not. I will stick with up&up!
1 out of 5 stars
27 December, 2025Verified purchase
(no review title)
Burned my skin. Do not recommend.
1 out of 5 stars
Thumbs down graphic, would not recommend
21 December, 2025Verified purchase
BURNS
This item is too sensitive for my skin, it burned so much! If you do use it only put it on the pimple not anywhere else around it. I love the other benzo peroxide that is less concentrated (right next to it)
1 out of 5 stars
20 December, 2025Verified purchase
(no review title)
My skin was too sensitive to use this product.
1 out of 5 stars
Thumbs down graphic, would not recommend
17 December, 2025Verified purchase
Watch out what you put on your skin
I bought this product for my acne, I’ve used other acids such as glycolic acid, salicylic acid, and other stuffs for my sling pro acne, and nothing has burned or damaged my skin, until now. I used this product for few days, and now my skin is really bad and burned, like if I was allergic to it. My recommendation is to watch out if you have a sensitive skin or you are allergic. I’ve had my skin in this way for 3 days!!