Desitin Maximum Strength Baby Diaper Rash Cream with Zinc Oxide - 4oz
New at target
$6.99
In Stock
Eligible for registries and wish lists
At a glance
About this item
Additional product information and recommendations
Discover more options
- $4.79was $5.99 New lower price4.8 out of 5 stars with 65 ratings
Frequently bought together
- $8.49 - $56.99Select items on clearance4.7 out of 5 stars with 19751 ratings
More to consider
Related Categories
Guests are saying
Desitin Maximum Strength Original Zinc Oxide Paste is a highly effective solution for diaper rash, praised for its thick texture that creates a protective barrier. Guests appreciate its fast-acting relief, often seeing improvements within one or two diaper changes. The formula contains 40 zinc oxide, making it suitable for sensitive skin. Many guests highlight its convenience and the fact that a little goes a long way, making it a staple in their baby care routine.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.7 out of 5 stars with 5161 reviews
81% would recommend
310 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
28 September, 2026Verified purchase
Works great
I use this for my face ironically. It’s a great barrier booster and has anti inflammatory properties! I have destroyed mine from using to many harsh products, so this has been very helpful. I only use it once a week as a face mask or as a spot treatment on other days. I am no dermatologist lol so use at your own risk!
5 out of 5 stars
25 September, 2026
originally posted on influenster.com

10/10
Desitin paste works really well for diaper rash. It has a thick texture and a little goes a long way. It soothes and protects the skin. I would definitely recommend it for babies with diaper rash.
5 out of 5 stars
Thumbs up graphic, would recommend
13 September, 2026Verified purchase
The Only Cure for Diaper Rash
The Desitin Maximum Strenth Paste is the cure all for diaper rash. Whenever my son’s bottom is irritated, the desitin helps to soothe and relief the irritation immediately unlike other brands we’ve tried. The texture is thick but it absorbs well on the skin. I recommend applying with a diaper cream applicator so the cream doesn’t stick to your hands. This is a great value and always use it to the last drop. Overall a highly recommended product for diaper rash and sensitive skin.
5 out of 5 stars
13 September, 2026
originally posted on influenster.com

The Only Cure for Diaper Rash
The Desitin Maximum Strenth Paste is the cure all for diaper rash. Whenever my son’s bottom is irritated, the desitin helps to soothe and relief the irritation immediately unlike other brands we’ve tried. The texture is thick but it absorbs well on the skin. I recommend applying with a diaper cream applicator so the cream doesn’t stick to your hands. This is a great value and always use it to the last drop. Overall a highly recommended product for diaper rash and sensitive skin.
1 out of 5 stars
12 September, 2026
originally posted on influenster.com

NO
Our son was in the NICU and had a persistent diaper rash the entire time. Every time we used this product, the diaper rash would get worse and get so raw that it would start bleeding. Initially we thought it was just because he was not being changed enough, so when we got home, we tried again. His bottom was hurting so bad and again, started bleeding even though we were doing frequent diaper changes. Once we discontinued use of this product, his butt started to get better.
5 out of 5 stars
Thumbs up graphic, would recommend
6 September, 2026Verified purchase
Beat diaper rash with Desitin
We kept going round and round with diaper rash until this cream. Highly recommend. We were using aquaphor for a while, but the diaper rash kept coming back and we were having to treat with nystatin every couple weeks. Since switching to Desitin we haven’t been back to the nystatin once! Woohoo!
5 out of 5 stars
3 September, 2026
originally posted on influenster.com

Skin Care
I squeezed every last bit out of this tube, we love it that much! I use it for my babies when they have rashes or even just every diaper change to prevent skin breakdown of any type. I’ve used it to dredge my skin and it makes it so so hydrated and plump overnight! It’s easy to clean off and doesn’t leave a bad residue.
4 out of 5 stars
Thumbs up graphic, would recommend
3 September, 2026Verified purchase
(no review title)
Quite a bit thicker than other butt pastes. A little goes a long way!
5 out of 5 stars
2 September, 2026
originally posted on influenster.com

Quick solution to diaper chafing
When choosing a product to use on your baby’s skin, do not choose any one. You should know that you are choosing this cream. It worked so much for me that from one day to the next you can see the results. My baby escalded too much and this helped him. The chafing because of the diaper disappeared.
5 out of 5 stars
30 August, 2026
originally posted on influenster.com

Works great
My poor daughter is prone to diaper rashes but this paste works great and quickly to ease her discomfort! The smell is a little weird and strong but worth it
5 out of 5 stars
27 August, 2026
originally posted on influenster.com

Repairs, protects and soothes rashes quickly
This is the the the #1 product I reach for whenever it comes to my boys having a rash. It has that thick barrier protection texture that will definitely keep your little ones rash sealed from messes in the diaper. I love that it has 40% zinc oxide, along with the petroleum and lanolin. It seriously clears rashes so fast.
5 out of 5 stars
Thumbs up graphic, would recommend
21 August, 2026Verified purchase
(no review title)
Gave my son relief from his diaper rash and cleared it very quickly. Started working from the first application and so on. A little goes a long way!
1 out of 5 stars
21 August, 2026
(no review title)
This product STINKS. We bought Triple Paste instead and that one is odorless.
5 out of 5 stars
16 August, 2026
originally posted on influenster.com

Excelente producto
It is an excellent cream; I highly recommend it. It provided my baby with very quick relief, and best of all, a little goes a long way. The packaging makes application very convenient and ensures it stays securely closed.
5 out of 5 stars
Thumbs up graphic, would recommend
15 August, 2026Verified purchase
Perfect for babies!
Worked better than any other brand! Definitely will continue to buy.
5 out of 5 stars
12 August, 2026Verified purchase
(no review title)
Thick and effective. Worked well.
5 out of 5 stars
12 August, 2026
originally posted on influenster.com

A thick, protective diaper rash paste that soothes irritation and helps protect baby’s skin from moisture.
I’ve been really happy with the DESITIN Maximum Strength Original Zinc Oxide Paste. It has a thick, rich texture that creates a protective barrier and helps keep moisture away from the skin. I like using it when my baby’s skin looks irritated because it feels soothing and provides extra protection, especially overnight. A little goes a long way, and I appreciate that it contains 40% zinc oxide. Overall, it’s a great product to have on hand for diaper rash and sensitive skin.
5 out of 5 stars
11 August, 2026Verified purchase
(no review title)
Amazing stuff
5 out of 5 stars
Thumbs up graphic, would recommend
10 August, 2026Verified purchase
Diaper rash is gone
Helped tremendously with the diaper rash Has a smell but not horrible I like how it spreads very easily And the diaper rash is gone
5 out of 5 stars
9 August, 2026
originally posted on influenster.com

Powerful fast acting diaper rash cream!
Have gotten a number of times and will continue to. This works so well and and I’m still impressed with how quick it helps to relieve my babies pain and heal a rash!