New ArrivalsHalloweenChristmasGift IdeasClothing, Shoes & AccessoriesHomeFurnitureElectronicsToysVideo GamesGroceryHousehold EssentialsBeautyBabyKitchen & DiningSchool & Office SuppliesMovies, Music & BooksCharacter ShopSports & OutdoorsBackpacks & LuggagePersonal CareHealthPetsUlta Beauty at TargetTarget OpticalParty SuppliesGift CardsBullseye’s PlaygroundDealsClearanceTarget New Arrivals Target Finds #TargetStyleDía de MuertosStore EventsAsian-Owned Brands at TargetBlack Beyond MeasureMás QueWomen-Owned Brands at TargetLGBTQIA+ ShopTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Anti-Diarrheal Softgels - 24ct - up&up™ - 2 of 4Anti-Diarrheal Softgels - 24ct - up&up™ - 3 of 4Anti-Diarrheal Softgels - 24ct - up&up™ - 4 of 4
Anti-Diarrheal Softgels - 24ct - up&up™ - 1 of 4

Anti-Diarrheal Softgels - 24ct - up&up™

$8.19

In Stock

Eligible for registries and wish lists

At a glance

Sponsored

About this item

Highlights

  • Packaging may vary. Same trusted quality
  • Anti-diarrheal softgels offer relief from diarrhea
  • Active ingredient loperamide hydrochloride helps relieve symptoms such as bloating, cramps or gas
  • Pack includes 24 anti-diarrheal softgels for lasting use
  • At first symptoms, take 2 capsules for relief from uncomfortable diarrhea

Description

Don't let diarrhea or stomach troubles stop you from taking on your day — simply take these Anti-Diarrheal Softgels from up&up™ These softgel anti-diarrheal capsules are formulated with the active ingredient loperamide hydrochloride to offer you relief from diarrhea symptoms including bloating, gas or cramps. Easy to swallow, these anti-diarrhea softgels are great to carry with you for on-the-go relief.

We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Suggested Age: 12 Years and Up
Product Warning: Use caution while operating machinery, not for children under the age of 12, do not use if you have bloody or black stool, consult a doctor if you have a fever, consult a doctor if you are pregnant or nursing, consult a doctor if you have liver disease
Product Form: Gelcap
TCIN: 78294075
UPC: 311673177129
Item Number (DPCI): 245-05-5384
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

loperamide hcl' '2.0mg

Purpose

Anti-diarrheal

Uses

controls symptoms of diarrhea, including Travelers' Diarrhea

Directions

not for use in children under 12 years of age, drink plenty of clear fluids to help prevent dehydration caused by diarrhea., adults and children 12 years and over: 2 capsules after the first loose stool; 1 capsule after each subsequent loose stool; but no more than 4 capsules in 24 hours

Other information

Protect from Light do not use if carton or blister unit is open or tom avoid excessive heat above 40°C (104°F) see side panel for lot number and expiration date, store at 20-25°C (68°-77°F)

Inactive ingredients

butylated hydroxyanisole, edible ink, fd&c blue #1, gelatin, glycerin, glyceryl caprylate, polyoxyl 40 hydrogenated castor oil, purified water' '

Shipping details

Estimated ship dimensions: 1.14 inches length x 3.28 inches width x 3.96 inches height
Estimated ship weight: 0.05 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Q: Is this product packaged in individual tear-away packets?

submitted by JGE - 2 years ago
  • A: Hello - We appreciate your interest in this Anti-Diarrheal Softgels. I'd like to let you know that, they aren’t really push though, the paper needs to be peeled back first. We hope this information proves useful to you. - Steve

    submitted bySteve - 2 years ago
    Target staff support

Q: Is this product gluten-free? Thanks.

submitted by Tess - 3 years ago
  • A: Hi Tess- Great question! Yes, these Anti-Diarrheal Softgels are gluten free. Thanks for stopping by!

    submitted byMonica - 3 years ago
    Target staff support

Guests also viewed

Loperamide Anti-Diarrheal Caplets - 24ct - up&up™

$3.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.6 out of 5 stars with 1750 ratings

Imodium A-D Diarrhea Softgels - 24ct

$14.79
Get a coupon, $10 off a $20 purchase with a flu shot
4.3 out of 5 stars with 412 ratings

Gas Extra Strength Softgel - 72ct - up&up™

$3.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.6 out of 5 stars with 836 ratings

Pepto-Bismol 5 Symptom Stomach Relief - Liquicaps

$5.99 - $19.89
Get a coupon, $10 off a $20 purchase with a flu shot
4.8 out of 5 stars with 328 ratings

Discover more options

Loperamide Anti-Diarrheal Caplets - 24ct - up&up™

$3.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.6 out of 5 stars with 1750 ratings

Imodium A-D Diarrhea Softgels - 24ct

$14.79
Get a coupon, $10 off a $20 purchase with a flu shot
4.3 out of 5 stars with 412 ratings

Imodium Anti-Diarrheal caplets - 24ct

$11.79
Get a coupon, $10 off a $20 purchase with a flu shot
3.8 out of 5 stars with 764 ratings

Imodium A-D Caplets - 12ct

$8.89
Get a coupon, $10 off a $20 purchase with a flu shot
3.6 out of 5 stars with 607 ratings

Related Categories

4.7 out of 5 stars with 546 reviews
effectiveness: 4.63 out of 5
quality: 4.5 out of 5
value: 4.21 out of 5
88% would recommend
35 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
4 August, 2025

Buy these

Holy cow, these work incredible.
Madisonnorthrup13
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
28 July, 2025Verified purchase

Does the job quickly

Works quickly. A little overpriced for generic brand. Love that it is soft gel coated. Easy to swallow.
Bronx gal
effectiveness: 5 out of 5
quality: 5 out of 5
value: 3 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
16 June, 2025Verified purchase

Helps with chronic tummy issues

I have chronic stomach issues and these save me every time I need to go out but am having a flare up. They work just as good, if not better, than the name brand.
Alicia
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
2 out of 5 stars
Thumbs down graphic, would not recommend
24 May, 2025Verified purchase

Worst Packaging Ever

I bought the Anti-Diarrheal capsules and had a very very difficult experience. The packaging is totally unacceptable. It takes a sharp object to get it open. The product itself is effective but opening it is frustrating to say the least.
Up and Up Anti Diarrheal
effectiveness: 5 out of 5
quality: 1 out of 5
value: 3 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
28 March, 2025Verified purchase

Works great

This medication works quickly and efficiently. Which is a good thing if you’re in the need for it. We’ve used the name brand stuff in the past, and this is just as good. Great value. We keep this on hand at home, for any just in case sickness.
PureMichelle
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
19 February, 2025Verified purchase

Poop happens... this helps.

Must have when you have a stomach that gets upset at the drop of a hat. It’s fast acting and makes traveling easier knowing that it will keep tummy troubles away.
Mel
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
6 December, 2024Verified purchase

Up and Up Anti-Diarrheal Softgels

These used to work great but since they changed packaging I am guessing ingredients and or sources of ingredients have changed drastically - they do not work well anymore whatsoever.
Kada
quality: 1 out of 5
effectiveness: 1 out of 5
value: 1 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
16 November, 2024Verified purchase

BUY THESE

I have IBS. These work perfectly!!!! Use them and I can work all day long
RBB
1 guest found this review helpful. Did you?
1 out of 5 stars
Thumbs up graphic, would recommend
21 September, 2024Verified purchase

NOT DELIVERED CORRECTLY

I am handicapped and can’t get deliveries left OUTSIDE on doorstep they should of waited till I buzzed them in because package will be stolen.
Dishmac
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
11 April, 2024Verified purchase

A need!

Perfect to have these on hand incase of upset stomach / emergency
Natalie
value: 5 out of 5
quality: 5 out of 5
effectiveness: 5 out of 5
1 guest found this review helpful. Did you?
3 out of 5 stars
14 January, 2024Verified purchase

Witness Protection Pills

They act like these pills are in witness protection because the plastic packaging is impossible to get off without cutting open.
Io
34 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
27 November, 2023Verified purchase

The Best

It works just as well even though it is generic. Took care of my problem
2 Yorkies
quality: 5 out of 5
effectiveness: 5 out of 5
value: 5 out of 5
3 guests found this review helpful. Did you?
2 out of 5 stars
Thumbs down graphic, would not recommend
3 September, 2023

Didn't work

Didn’t work, I had a terrible time, these were not useful
Missing pieces
effectiveness: 1 out of 5
quality: 1 out of 5
value: 1 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
14 July, 2023Verified purchase

EASY & NECESSARY

EASY ON THE STOMACH FOR ME AND A NECESSARY MEDICINE AS ONE AGES OR HAS SUDDEN UPSET FREQUENTLY. SEEMS TO WORK JUST AS GOOD AS NAME BRAND AND MUCH BETTER THAN PEPTO.
BIRDIE
effectiveness: 5 out of 5
quality: 5 out of 5
value: 4 out of 5
6 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
27 May, 2023Verified purchase

Life savers lol

They work just as well as the name brand
Heather
effectiveness: 5 out of 5
value: 5 out of 5
quality: 5 out of 5
4 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
3 May, 2023Verified purchase

Horrible packaging

These softgels are effective, but I won't be buying them again. The packaging is awful! You need a pair of scissors to get the pills out of the blister packaging, and even then it's difficult and you'll probably cut yourself on the super-sharp plastic edges. It makes no sense. If I carry these in my purse to use when I'm away from home, I guess I'm supposed to carry scissors, too? I'm happy to pay more for Imodium tablets that come in a BOTTLE.
Squeakalicious
effectiveness: 5 out of 5
value: 1 out of 5
quality: 4 out of 5
23 guests found this review helpful. Did you?
5 out of 5 stars
19 April, 2023Verified purchase

Gel is better

Works and goes down better.
JM
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
12 April, 2023Verified purchase

These are better than the name brand

The up & up anti-diarrheal soft gels are a lot better than the Imodium soft gels, and they cost about half as much. The up&up are cheaper than the I only have two complaints – that have nothing to do with the quality of this product – is that they no longer carry them in the bottles of 48 and 72 counts; and they seem to be out of stock frequently.
shopaholicaz81
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
3 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
21 March, 2023Verified purchase

Affordable anti diarrhea

I appreciate how well this product works and the price is so much better! I promise it is just as good as the name brand, but affordable!
ssheby
3 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
21 January, 2023Verified purchase

Relief fast

Helps stop diarrheal quickly. I highly recommend the soft gels.
HeatherSH
effectiveness: 5 out of 5
quality: 5 out of 5
value: 5 out of 5
2 guests found this review helpful. Did you?

Get top deals, latest trends, and more.

Privacy policy

Footer

About Us

About TargetCareersNews & BlogTarget BrandsBullseye ShopSustainability & GovernancePress CenterAdvertise with UsInvestorsAffiliates & PartnersSuppliersTargetPlus

Help

Target HelpReturnsTrack OrdersRecallsContact UsFeedbackAccessibilitySecurity & FraudTeam Member ServicesLegal & Privacy

Stores

Find a StoreClinicPharmacyTarget OpticalMore In-Store Services

Services

Target Circle™Target Circle™ CardTarget Circle 360™Target AppRegistrySame Day DeliveryOrder PickupDrive UpFree 2-Day ShippingShipping & DeliveryMore Services
PinterestFacebookInstagramXYoutubeTiktokTermsCA Supply ChainPrivacy PolicyCA Privacy RightsYour Privacy ChoicesInterest Based AdsHealth Privacy Policy