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Mucinex 12hr Cold & Fever Multi-Symptom Caplets - 16ct - 2 of 4Mucinex 12hr Cold & Fever Multi-Symptom Caplets - 16ct - 3 of 4Mucinex 12hr Cold & Fever Multi-Symptom Caplets - 16ct - 4 of 4
Mucinex 12hr Cold & Fever Multi-Symptom Caplets - 16ct - 1 of 4

Mucinex 12hr Cold & Fever Multi-Symptom Caplets - 16ct

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New at  target 
$14.99

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At a glance

About this item

Highlights

  • NEW MUCINEX 12 HOUR COLD & FEVER MULTI-SYMPTOM TABLETS: Introducing the first and only over-the-counter 12 hour cold and flu medicine for adults that reduces fever and relieves cough, chest congestion, and body pain
  • ALL DAY OR NIGHT MULTI-SYMPTOM RELIEF: One dose lasts 3x longer than most cold & flu medicines (compared to 1 dose of 4-hour medicine without re-dosing)
  • FEVER REDUCTION & HEADACHE RELIEF: Contains Naproxen Sodium which reduces fever and relieves headache & minor pains
  • COUGH SUPPRESSANT: Contains Dextromethorphan HBr which helps control cough
  • EXCESS MUCUS RELIEF: Contains Guaifenesin which thins & loosens mucus and relieves chest congestion
  • POWERFUL OVER-THE-COUNTER MEDICATION: Just 1 dose (2 tablets) in the morning and 1 dose (2 tablets) at night relieves symptoms for a full 24 hours, so you can say goodbye to re-dosing every 4 hours
  • INNOVATIVE MUCINEX TECHNOLOGY: Bi-layer tablet with immediate and extended-release technology controls your symptoms all day or night
  • TRUSTED BRAND: Mucinex is the #1 most trusted among physicians for cough & cold symptoms (IQVIA, ProVoice Survey, March 2026)

Description

Introducing Mucinex 12 Hour Cold & Fever Multi-Symptom Bi-Layer Tablets: The first and only over-the-counter cold and flu medicine that provides 12 hours of powerful multi-symptom relief from fever, headache, body pain, cough, and chest congestion. Thanks to our unique bi-layer tablet technology with an immediate-release layer and an extended-release layer, one dose lasts 3x longer than most cold and flu medicines.* Starts to release medicine immediately, while the extended-release layer keeps working for 12 hours.

Our one-of-a-kind formula contains powerful active ingredients that provide all day control of your worst cold and flu symptoms:
Naproxen Sodium reduces fever and helps relieve headache and minor pains.
Dextromethorphan HBr is a cough suppressant that helps control cough.
Guaifenesin is an expectorant that thins & loosens mucus and relieves chest congestion.

Say goodbye to re-dosing every 4 hours: just 1 dose (2 tablets) in the morning and 1 dose (2 tablets) at night keeps you covered for a full 24 hours.

*compared to 1 dose of 4-hour medicine without re-dosing.
Suggested Age: 12 Years and Up
Product Warning: Consult a doctor if you have high blood pressure, consult a doctor if you have thyroid disease, consult a doctor if you are pregnant or nursing, consult a doctor if you have heart disease, consult a doctor if you have diabetes, not for children under the age of 12
Product Form: Caplet
Primary Active Ingredient: Naproxen Sodium
Package Quantity: 16
TCIN: 91695030
UPC: 363824997759
Item Number (DPCI): 094-14-7013
Origin: Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

dextromethorphan hbr' '30.0mg guaifenesin' '600.0mg naproxen sodium (naproxen 100) (nsaid)¹' '110.0mg ' '

Purpose

Cough suppressant Expectorant Pain reliever / fever reducer

Uses

■ helps loosen phlegm (mucus) and thin bronchial secretions to clear mucus from the airways and make coughs more productive ■ temporarily relieves: ■ cough due to minor throat and bronchial irritation from the common cold or inhaled irritants ■ the intensity of coughing ■ the urge to cough to help you sleep ■ minor aches and pains due to headache and the common cold ■ temporarily reduces fever

Directions

Directions ■ do not crush, chew, or break extended-release tablet ■ do not take more than directed ■ take each dose with a full glass of water ■ adults and children 12 years and older: take 2 extended-release tablets every 12 hours; not more than 4 extended-release tablets in 24 hours ■ children under 12 years of age: do not use

Inactive ingredients

inactive ingredients: croscarmellose sodium, fd&c red no. 40, hydroxyethyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium bicarbonate, sodium lauryl sulfate

Shipping details

Estimated ship dimensions: 5.03 inches length x 3.5 inches width x 1.14 inches height
Estimated ship weight: 0.09 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: Does it make you tired

submitted by Anonymous - 1 month ago
  • A: Thank you for your question about our Mucinex® 12 HR Cold & Fever Multi-Symptom extended release tablets! The active ingredient dextromethorphan has been shown to produce drowsiness in some patients. We recommend that you speak with your healthcare provider to determine if this product is best for you. Hope this helps!

    submitted byMucinex Team - 1 month ago
    Brand expert

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Guests are saying

Mucinex 12 Hour Cold and Fever Multi-Symptom tablets are a reliable choice for guests seeking effective relief from various cold symptoms. Many guests appreciate the long-lasting effects, with relief lasting up to 12 hours. The product is praised for its ability to tackle headaches, body aches, cough, and chest congestion, making it a convenient all-in-one solution. Its easy-to-swallow tablets and fast-acting formula make it a must-have during cold and flu season.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.8 out of 5 stars with 1978 reviews
    quality: 5 out of 5
    value: 5 out of 5
    100% would recommend
    1 recommendations
    5 out of 5 stars
    21 October, 2026
    originally posted on Mucinex
    Image

    Very helpful!!

    [This review was collected as part of a promotion.] My husband was hesitant to try this but we took it first sign of his cold. He’s usually a baby about his cold symptoms but felt better that day and it cleared his cold up in two days!! Love it!
    Did you find this review helpful?
    5 out of 5 stars
    21 October, 2026
    originally posted on Mucinex
    Image

    Fast acting

    [This review was collected as part of a promotion.] I stock up on this medication every year in preparation for the cold and flu season. I have yet to need to use it this year but I know when I do it will work quickly
    Did you find this review helpful?
    5 out of 5 stars
    21 October, 2026
    originally posted on Mucinex
    Image

    Great

    [This review was collected as part of a promotion.] It work meeti la for me when I got covid and was trying to recover . The formulation was great. It was accessible to me when I needed it the most. Lasted a good 12 hours and had no issues taking it I just disliked the taste of it but it still was good. It was easy to absorb when taking
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    20 October, 2026

    The cold and flu magic pill.

    My new holy grail. I used to bean avid believer in the Sudafed that you had to get from the pharmacist but due to an issue with selling them I opted to try this Mucinex and boy was I relieved in just a matter of minutes it seemed. It not only tackled what the Sudafed couldn’t it made me feel so much better and I could feel all the mucus being “broken” up. This is going to be a staple in my medicine cabinet going forward.
    Kalani916
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    4 out of 5 stars
    20 October, 2026
    originally posted on Mucinex
    Image

    They work very well

    [This review was collected as part of a promotion.] Mucinex 12 HR cold & fever multi symptom pills have been a life savior. I’ve always struggled with finding the right medication for cold like symptoms but these have worked perfectly well. After using them for several days, I could really see a difference in my symptoms and how much my health had improved after a short amount of time. I would highly recommend this brand when suffering from cold like symptoms.
    SILVIAB
    Did you find this review helpful?
    5 out of 5 stars
    20 October, 2026
    originally posted on Mucinex
    Image

    Effective

    [This review was collected as part of a promotion.] Was feeling under the weather not too long ago and tried this product. It definitely helped relieve my symptoms and I was able to sleep in peace. The 12 hour effectiveness had me ready to go in the morning.
    TomS
    Did you find this review helpful?
    5 out of 5 stars
    20 October, 2026
    originally posted on Mucinex
    Image

    Great relief in minutes

    [This review was collected as part of a promotion.] I’m really happy with this product because it works really well and helps relive cold and fever symptoms in just a few minutes after taking it. I gotta say that the taste is a little bit weird but I don’t really care since it is still effective. Overall I think it’s a great product to have a home, specially during these cold and flu season
    LauraA
    Did you find this review helpful?
    5 out of 5 stars
    20 October, 2026
    originally posted on Mucinex
    Image

    Cold or fever

    [This review was collected as part of a promotion.] If you have a colder fever, this Mucinex multisymptom pill will relieve your fever, headache and body pain. You’re coughing, chest, congestion, and thins and loosens mucus. I highly recommend!
    TiyennaS
    Did you find this review helpful?
    5 out of 5 stars
    20 October, 2026
    originally posted on Mucinex
    Image

    easy and effective

    [This review was collected as part of a promotion.] i felt almost instant relief! these meds helped my symptoms and it was so easy! i’ve always loved mucinex but these will be a repurchase for sure!
    carlyG
    Did you find this review helpful?
    5 out of 5 stars
    19 October, 2026
    originally posted on Mucinex
    Image

    Works great.

    [This review was collected as part of a promotion.] Love that it works with multi symptoms, and I highly recommend this Mucinex multi symptoms medicine. Any brand from Mucinex is always in my cabinet anytime it's needed. This company makes great medication that works and works fast.
    HellenA
    Did you find this review helpful?
    5 out of 5 stars
    19 October, 2026
    originally posted on Mucinex
    Image

    Love it

    [This review was collected as part of a promotion.] It delivers dependable. Sustained relief when dealing with heavy congestion and seasonal cold systems. The extended release formula stands out because it keeps working throughout a full work shift or overnight without having to redose every 4-6 hours. It effectively thins out stubborn chest mucus to make coughs more productive while easing mild fevers and body aches. Best to have it.
    NolanT
    Did you find this review helpful?
    5 out of 5 stars
    19 October, 2026
    originally posted on Mucinex
    Image

    Effective Cold & Flu Relief that Lasts!

    [This review was collected as part of a promotion.] Mucinex 12 Hr Cold & Fever Multi-Symptom is a great product to have on hand during cold and flu season. I love that it provides up to 12 hours of release, so I don’t have to take medication throughout the day constantly. It helps relieve coughing, chest congestion, headaches, body aches, and fever while loosening mucus to make breathing more comfortable. The multisymptom formula is convenient because it addresses several symptoms in one product. I would definitely recommend Mucinex to anyone looking for reliable, long-lasting codeine and flu relief. 
    LaDonnaT
    Did you find this review helpful?
    5 out of 5 stars
    19 October, 2026
    originally posted on Mucinex
    Image

    Definitely recommend it.

    [This review was collected as part of a promotion.] Love mucinex I've always got it in my medicine cabinets because it works so well. I came down with a cold this last week with a slight fever and took this and my fever went away as well as my cold. I can't say enough good things about this. I will always recommend it it.
    Did you find this review helpful?
    5 out of 5 stars
    19 October, 2026
    originally posted on Mucinex
    Image

    Works quickly

    [This review was collected as part of a promotion.] Woke up sick so glad I had this I was worried because I have never used this medicine before but it worked amazingly. There was no foul smell or taste to it easy pill to take not to bug I washed it down with juice or water. I definitely recommend this if sick.
    Did you find this review helpful?
    5 out of 5 stars
    19 October, 2026
    originally posted on Mucinex
    Image

    Love that it lasts up to 12 hours!

    [This review was collected as part of a promotion.] Works really well for me when I have a bad cold. Helps with coughing, congestion and body aches. And it lasts up to 12 hours so I don’t have to keep taking medicine throughout the day.
    Did you find this review helpful?
    5 out of 5 stars
    19 October, 2026
    originally posted on Mucinex
    Image

    The release last long

    [This review was collected as part of a promotion.] The extended release is great. I only needed morning an night helped me with thin the mucus and stop the coughing so I could sleep. I like that it handles fever and cough in one plill and last 1w hours.
    Did you find this review helpful?
    5 out of 5 stars
    18 October, 2026
    originally posted on Mucinex
    Image

    Loosened mucus and made cough more productive.

    [This review was collected as part of a promotion.] This worked for me when I was sick! It helped reduce my symptoms and I was able to get through work without coughing every 5 minutes, and when I did cough it was more productive. I’m grateful, my coworkers are grateful, and I would buy this again!
    BrianneM
    Did you find this review helpful?
    5 out of 5 stars
    18 October, 2026
    originally posted on Mucinex
    Image

    Lasts 12 hours so less time spent taking medicine, and more time feeling better

    [This review was collected as part of a promotion.] This is my go-to when a cold hits hard. One dose covers the whole lineup — fever, headache, body aches, cough, and chest congestion — for a full 12 hours, so I'm not re-dosing every few hours or juggling three different bottles.Easy 5 stars from me.
    NimatD
    Did you find this review helpful?
    5 out of 5 stars
    18 October, 2026
    originally posted on Mucinex
    Image

    Loosens up mucous

    [This review was collected as part of a promotion.] Mucinex 12hr cold and fever loosened up the mucous I felt building up in my chest and it made it much easier to expel. Also helped reduce my achey symptoms
    KassidyS
    Did you find this review helpful?
    5 out of 5 stars
    18 October, 2026
    originally posted on Mucinex
    Image

    Cold relief!

    [This review was collected as part of a promotion.] Provides effective relief of cold and fever symptoms! It helps control coughs and loosens mucus. Definitely a product that a recommended and one that my girlfriend swears by!
    JayD
    Did you find this review helpful?

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