CLINICALLY TESTED 48 HOUR HYDRATION A multi-level, hydrating serum formulated with dual weight polyglutamic acid, glycerin, osmolytes and ectoin that provide excellent skin moisturization, improve the skin barrier, and support skin's Natural Moisturizing Factor. Great for dry skin.
CLINICALLY PROVEN RESULTS: After just one use: +93% noticed immediate improvement in hydration +96% agreed it gave them a glowy look After one week of daily use: +100% agreed it made their skin appear more youthful +100% agreed it made their skin more plump +96% agreed the product made their skin appear more radiant
To Use: Apply evenly to dry, cleansed skin. Follow with moisturizer and sun protection.
Scent: Unscented
Health Facts: No Fragrance Added
Product Form: Serum
Beauty Purpose: Plumping, Moisturizing
Recommended Skin Type: Combination, Dry, Normal
TCIN: 91781193
UPC: 810129110302
Item Number (DPCI): 037-14-3911
Origin: Made in the USA
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.
CAUTION: For external use only. Keep out of reach of children. Discontinue use if irritation occurs. Use only as directed.
Shipping details
Estimated ship dimensions: 5.31 inches length x 1.73 inches width x 1.49 inches height
Estimated ship weight: 0.42 pounds
Return details
This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
Q: Do you use multiclench serum in conjunction with multiclench spray or in place of? If you use together, which should come first?
submitted by AigeP - 5 months ago
A: Hi! We would recommend applying our Multi-Quench Serum before moisturizing and applying our Multi- Quench as needed throughout the day to refresh. We hope this helps.
submitted byPrequel - 3 months ago
Brand expert
Q: Should you use this before or after Vitamin C?
submitted by Abbey - 5 months ago
A: We recommend starting with Lucent C ( Vitamin C ) allow some dry time before applying Multi Quench Plumping Hydration.
submitted byPrequel - 5 months ago
Brand expert
Q: Would this be considered more of a moisturizer or hydrator?
submitted by detailsdetails - 6 months ago
A: Prequel Multi‑Quench Plumping Hydration is a hydrating serum designed to boost moisture in your skin. For best results, we recommend layering it under your favorite moisturizer to lock in hydration and maximize its benefits.
submitted byPrequel - 6 months ago
Brand expert
Q: How much do you apply per use and how often should you use this product?
submitted by Sj - 6 months ago
A: Hi there! We recommend applying 1 pump (or a small, pea-to-dime sized amount) per use. This should be enough to create a thin, even layer over the face and neck. A little goes a long way!
The serum can be used once or twice daily, depending on your routine and hydration needs. It’s best applied to clean, slightly damp skin after cleansing and before moisturizer. If using in the morning, be sure to follow with sunscreen.
submitted byPrequel - 6 months ago
Brand expert
Q: Can you use it over makeup when your makeup starts to feel dry towards the end of the day?
submitted by JennyBosak - 7 months ago
A: You can try using the Prequel Multi-Quench Hydration Face Mist instead, it’s designed to refresh and hydrate your skin over makeup without disturbing it, perfect for when your makeup starts to feel dry toward the end of the day.
submitted byPrequel - 7 months ago
Brand expert
Q: Does this have a fragrance
submitted by Mkp - 7 months ago
A: I read in details it’s unscented
submitted bySalPAL - 7 months ago
Q: How Similar Is This To hyaluronic acid?
submitted by B - 8 months ago
A: Polyglutamic Acid (PGA) and Hyaluronic Acid (HA) are both moisturizing acids used in skincare, but they have distinct differences and benefits. PGA (featured in our serum) has been shown to be a better hydrator than HA. It helps restore skin elasticity, smooth visual wrinkles, and increase production of the skin's Natural Moisturizing Factor (NMF).
submitted byPrequel - 8 months ago
Brand expert
Q: Is this product gluten free?
submitted by tayhungerford - 8 months ago
A: Yes, our Multi-Quench serum is gluten-free.
submitted byPrequel - 8 months ago
Brand expert
Q: Does this product leave the face feeling sticky after applying??
submitted by Nightengale - 8 months ago
A: Our Multi-Quench Serum shouldn't leave a sticky or tacky feeling after application, but we'd recommend layering a moisturizer like our Half & Half Fluid or AM/PM Moisturizer over top, if you are experiencing any stickiness.
submitted byPrequel - 8 months ago
Brand expert
Q: How long does this take to absorb into skin? How long do i need to wait to apply the next product?
submitted by Raytwn - 8 months ago
A: We recommend waiting 30 seconds to a minute for the product to fully absorb into the skin and then applying other products, over top.
This serum is a standout addition to any skincare routine, offering exceptional hydration and a lightweight feel that many guests appreciate. It effectively plumps and softens the skin, making it ideal for layering under other products. While some guests experienced irritation, the majority found it to be a reliable solution for dry skin, enhancing overall texture and moisture levels. Its versatility allows for use day and night, making it a must-try for anyone seeking a boost in hydration.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.5
4.5 out of 5 stars
770 star ratings
4.5 out of 5 stars with 770 reviews
62% would recommend
35 recommendations
4 out of 5 stars
25 August, 2026
originally posted on Prequel
Great Hydrator
Great first step to your skincare routine. Feels very hydrating and keeps your skin moisturized all day.
Jgnieves
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5 out of 5 stars
Thumbs up graphic, would recommendWould recommend
10 August, 2026Verified purchase
(no review title)
Really hydrating! Wonderful product.
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5 out of 5 stars
7 August, 2026Verified purchase
Best serum
I love it my skin looks like glass skin now
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5 out of 5 stars
Thumbs down graphic, would not recommendWould not recommend
6 August, 2026Verified purchase
Great Serum
I like the serum, super light weight, I can feel my skin getting more hydrating whenever I use it.
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5 out of 5 stars
5 August, 2026
originally posted on Prequel
Excellent hydrating serum
This serum is amazing! I’ve gotten many compliments on how excellent my skin looks while using this. My skin is no longer dry. It looks dewy and soft.
MeganS
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5 out of 5 stars
2 August, 2026
originally posted on Prequel
The BEST hydrating serum at all price points
I have gone through probably 10 of these serums. I've used it since it first came out. I like trying new products so I would go back and forth, but always come back to this so I just stopped buying anything else. I usually get at least 2 during a sale. I use it on my face next and chest, but I will use it after shaving and anywhere I am dry. Even though I slather it on the bottle lasts a long time. It's such a high quality serum for the price and I don't feel like I need to hoard it for my face. It feels immediately hydrating, and is a simple effective serum. I am almost done with my first month of accutane and this has been one of the best products in keeping the side effects at bay.
lnyyy
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1 out of 5 stars
Thumbs down graphic, would not recommendWould not recommend
2 August, 2026Verified purchase
(no review title)
I don’t know what it is about this serum but it burns my skin and causes break outs.
Caroline
1 guest found this review helpful. Did you?
3 out of 5 stars
31 July, 2026
originally posted on Prequel
Multi-Quench Serum
There is something in this serum that after applying my whole face turns completely red. It doesn't seem to break me out though. Feels a little sticky/tacky for awhile after. Out of this whole Prequel set this is my least favorite.I do have sensitive skin.
ndavidson068
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5 out of 5 stars
30 July, 2026
originally posted on Prequel
Moisture to the rescue!
Wonderful moisture! I’m 70 so of course I’m battling dry skin but the moisture quench along with the 1/2 and 1/2 are a perfect combo!
MicheleinCharlotte
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5 out of 5 stars
30 July, 2026
originally posted on Prequel
Repurchased countless times
I’ve repurchased this for years— it’s lovely, lightweight, and great for layering under my retinal. Keeps my skin hydrated in bitter Minnesota winters!
SCL85
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5 out of 5 stars
26 July, 2026
originally posted on Prequel
Looking for Super Hydration? Here it is...
Love, love, love this serum along with the Lucent-C. I was experiencing crepey cheek skin and nothing was helping. When I exfoliated with the Multi-Acid Milk Peel and applied the Multi-Quench and Lucent-C serum the next day, my face looked amazing. Highly recommend the Multi-Quench Serum along with Prequels other products for further hydration.
Diane Mackintosh
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5 out of 5 stars
26 July, 2026
originally posted on Prequel
Very hydrating
My skin feels plumper. It’s a little sticky but I assume that’s because it’s so hydroscopic. I’ve noticed that my wrinkles aren’t as noticeable when my skin is hydrated.
Redengbldr
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2 out of 5 stars
25 July, 2026
Fix the pump!!
I have bought this product twice, and both times the pump has stopped functioning correctly. First, the amount of product that would dispense was greatly reduced and just sprayed unevenly. This time, when pressed down, the pump will remain in the down position. Very annoying. Both times this happened within a few weeks of using the product. The product itself is lightweight which I appreciate and isn’t as sticky as other folks mention in the reviews.
Mt917
2 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommendWould recommend
24 July, 2026Verified purchase
(no review title)
I've been using this multi quench for several months. It's a good way to build up to retinol, which hyper sensitive face skin couldn't tolerate before.
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5 out of 5 stars
23 July, 2026
originally posted on Prequel
Wonderful texture
Goes on smoothly and plumps my skin. I really like it!
Irene T-S
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5 out of 5 stars
23 July, 2026
originally posted on Prequel
Perfection
Perfect texture was easy to apply and absorbs nicely
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5 out of 5 stars
18 July, 2026
originally posted on Prequel
Great Product
Surprisingly good. Very refreshing and great to layer with.
CalamityJane
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5 out of 5 stars
14 July, 2026
originally posted on Prequel
Wow!
At 68 I have tried many products but none as effective as the Multi-Quench Serum. My skin loves this product and leaves me glowing. Not sticky..my skin looks plump and healthy. I have recommended this product to all my friends and I will reorder. Highly recommend!
Sharon M
3 guests found this review helpful. Did you?
5 out of 5 stars
11 July, 2026
originally posted on Prequel
My skins drinks up this quenching serum xo
I'm a bit obsessed with this hydration serum. I apply it each morning specifically to my forehead which often gets neglected. My skin immediately plumps and softens, especially with summertime ritual of swim caps and drying effect of chlorine.
Teresa K.
1 guest found this review helpful. Did you?
3 out of 5 stars
9 July, 2026
originally posted on Prequel
Very hydrating
Very hydrating but stings my face every time. Won’t repurchase for that reason.
