Similac NeoSure Powder Infant Formula - 13.1oz: Brain Development, Growth Support, Prematurity, Gluten-Free
$32.99 ($2.52/ounce)
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- $12.79($0.40/fluid ounce)4.1 out of 5 stars with 483 ratings
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- $12.79($0.40/fluid ounce)4.1 out of 5 stars with 483 ratings
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- $12.79($0.40/fluid ounce)4.1 out of 5 stars with 483 ratings
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Guests are saying
This formula is highly regarded for its effectiveness in promoting weight gain in premature infants, with many guests noting significant improvements in their baby's growth and health. While it has been beneficial for many, some guests have reported issues with gas and constipation. Overall, it is a popular choice among parents looking to support their baby's nutritional needs, especially for those who were born prematurely.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.0 out of 5 stars with 451 reviews
easy on tummy: 2.31 out of 5
easy to prepare: 3.97 out of 5
quality: 3.06 out of 5
value: 2.62 out of 5
34% would recommend
35 recommendations
5 out of 5 stars
10 July, 2026
originally posted on similac.com

Diaper bag must!
[This review was collected as part of a promotion.] These were a lifesaver with a newborn! They’re a great back up to keep in the diaper bag for on the go needs as well.
5 out of 5 stars
9 July, 2026
originally posted on similac.com

GREAT FOR WEIGHT GAIN
[This review was collected as part of a promotion.] my kids were so tiny when they were born now they’re so big🥹
5 out of 5 stars
8 July, 2026
originally posted on similac.com

Great product
[This review was collected as part of a promotion.] Buy this regularly and my daughter loves it and so do I! Makes going shopping so much easier!
5 out of 5 stars
7 July, 2026
originally posted on similac.com

Weight gain
[This review was collected as part of a promotion.] This is the formula my twins were given in the NICU, so it's what I trusted once we brought them home. Most importantly, they were able to gain the weight they needed quickly, which gave us so much peace of mind. I'm thankful we found a formula that worked so well for them.
5 out of 5 stars
7 July, 2026
originally posted on similac.com

Helped our babies grow
[This review was collected as part of a promotion.] The only formula I would trust for my 4lb newborn twin boys. We used this product and the powdered formula version to help our boys gain weight and after 3 months, we switched to the Pro-Total Comfort Gentle (replaced with the 360 Total Care Gentle now) to be easier on our babies’ sensitive stomachs.
1 reply from Consumer Relations team - 14 days ago
We would like to learn more about your experience and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 05017518 when you call.
5 out of 5 stars
14 January, 2026
originally posted on similac.com

Great Formula
Best bang for your buck by buying the larger can. Love this formula and all the benefits it has for my baby.
5 out of 5 stars
11 November, 2025
originally posted on similac.com

GREAT BRAND !
Love this brand , helps my baby weight and she loves it n she don’t spit up
4 out of 5 stars
23 September, 2025
originally posted on similac.com

grandson news
My grandson has adjusted to the formula great. he doesn't get upset stomachs nor spits up
5 out of 5 stars
20 September, 2025
originally posted on similac.com

N/a
My baby’s milk and is been amazing for him. Since birth
5 out of 5 stars
21 August, 2025
originally posted on similac.com

Perfect for prematures
My daughter has grown healthy and happy. This formula helped to achieve her milestones and has been very gentle to her stomach,however mild gassy.
1 reply from Consumer Relations team - 11 months ago
We would like to learn more about your baby's experience with NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04869767 when you call.
5 out of 5 stars
3 March, 2025
originally posted on similac.com

Similac Neosure milk and Similac slow flow nipples
My son was born prematurely and had to stay in the NICU. While I developed my milk supply, I supplemented multiple feedings with Similac Neosure Ready-to-feed 2oz bottles. I purchased two 48 count cases and the single use similac slow flow nipples to continue familiarity in feedings at home. He has tripled his weight and I’m happy with this brand. I am struggling to find the 2oz bottles and would love if a representative reached out and assisted with my purchase. Traveling with those individual bottles and nipples has made traveling a breeze. Multiple fit in the diaper bag and I can carry around many days worth of feedings without the need for a refrigerator.
5 out of 5 stars
8 February, 2025
originally posted on similac.com

Works well for Preemie Growth
My baby has been on neosure since birth. She was born at 33 weeks and is now caught up at 5 months. She does seem to have some trouble with gas and spits up a good bit. But overall I'm happy with her development.
1 reply from The Consumer Relations Team team - 1 year ago
We're glad your little one is a fan of Similac NeoSure and we would like to learn more about her experience. Please give our team a call at 800-850-7677, M-F from 8:30am-5pm, ET & reference customer# 04777804. We hope to hear from you soon!
5 out of 5 stars
8 February, 2025
originally posted on similac.com

Great item
My child loves it she is not gassey or spitting up since i switched her to the powder
3 out of 5 stars
6 February, 2025
originally posted on similac.com

For my Premie
My baby was on neosure for a short while when we came home from the hospital. We switched to 360 sensitive because neosure left him very gassy.
1 reply from The Consumer Relations Team team - 1 year ago
Thanks for your review!. We're glad your little one is doing well on Similac 360 Total Care Sensitive and we would like to learn more about his troubles with Similac NeoSure. Feel free to give us a call when you have a few minutes to spare: 800-850-7677, M-F from 8:30am-5pm, ET & reference customer# 04777651.
4 out of 5 stars
5 February, 2025
originally posted on similac.com

Satisfied
The NICU started my baby on this formula. I wanted to switch to a cheaper competitor, but two pediatricians advised to stick with Similac Neosure because my baby was doing so well on it and doubled his weight! He does seem to have a lot of gas, but I will live with it since we are relieved to hear that has grown so much and went from the 27 percentile to 49 percentile for his age group.
1 reply from The Consumer Relations Team team - 1 year ago
Thanks for your review! We would like to learn more about your baby's experience with Similac NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04777195 when you call.
5 out of 5 stars
Thumbs up graphic, would recommend
28 January, 2025Verified purchase
Pediatrician recommended!
My infant tolerates this milk and has no digestion issues whatsoever I love it!
1 out of 5 stars
Thumbs down graphic, would not recommend
1 November, 2024Verified purchase
Dont use this formula
Don’t give this to your baby. My baby was born premature and this formula was given to her at NICU. We were sent home with the ready to feed bottles and those were good. But after that I used these cans and baby has been very fussy, vomiting, and really constipated. She even cries very loud out of nowhere and pushes a-lot. I feel so bad for her. Tomorrow I will be going to her pediatric because I cant see her in pain anymore. It’s been days since she last pooped.
1 reply from Abbott Nutrition Team team - 2 years ago
We would like to learn more about your baby's experience with Similac NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04736571 when you call. -The Similac Team
1 out of 5 stars
Thumbs down graphic, would not recommend
10 October, 2024
Caused major fussiness and reflux symptoms
First, let me lead with this formula is great for rapid weight gain for a preemie. My baby gained around 9oz a week, give or take, and caught up to a relatively “normal” newborn size around 1 month on it. But now on to the ugly. In NICU, they were using the premixed liquid Neosure, which she seemed to tolerate well, and we were sent home with the powder formula with a 24 calorie formulation (5.5oz of water to 3 scoops of formula.) For the first week or so, things were pretty good, but then I noticed that she started to sound congested, but I couldn’t get anything out of her nose. Fast forward a few weeks, we’ve had increased gassiness, fussing and refusing to sleep, and some pretty evident signs of reflux, such as several episodes of nasal reflux. We give mylicon drops like they’re going out of style and suction her nose to clear it of the backup, but overall it has not been a good experience for us as NICU/preemie parents.
1 reply from Abbott Nutrition Team team - 2 years ago
We would like to learn more about your baby's experience with Similac NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04724561 when you call. -The Similac Team
1 out of 5 stars
Thumbs down graphic, would not recommend
21 May, 2024
Caused fussiness and constipation
My baby was born at 34 weeks. Sent home with this formula. About a week later, he was constipated and very fussy all the time. When I switched his formula to Emfamil premie version, he was back to normal with regular bowels. I do not recommend this.
1 reply from Abbott Nutrition Team team - 2 years ago
We would like to learn more about your baby's experience with Similac NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04672941 when you call. -The Similac Team
4 out of 5 stars
20 April, 2024
originally posted on similac.com

Great formula
My baby was born at 34 weeks 2 days and this the only formula that has helped her gain weight she went from 4lbs to 8 in about a month