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Similac NeoSure Powder Infant Formula - 13.1oz: Brain Development, Growth Support, Prematurity, Gluten-Free - 2 of 4Similac NeoSure Powder Infant Formula - 13.1oz: Brain Development, Growth Support, Prematurity, Gluten-Free - 3 of 4Similac NeoSure Powder Infant Formula - 13.1oz: Brain Development, Growth Support, Prematurity, Gluten-Free - 4 of 4
Similac NeoSure Powder Infant Formula - 13.1oz: Brain Development, Growth Support, Prematurity, Gluten-Free - 1 of 4

Similac NeoSure Powder Infant Formula - 13.1oz: Brain Development, Growth Support, Prematurity, Gluten-Free

$32.99 ($2.52/ounce)

In Stock

Eligible for registries and wish lists

At a glance

About this item

Highlights

  • NEOSURE IS THE #1 SELLING PRETERM POST-DISCHARGE INFANT FORMULA
  • FROM THE MAKER OF THE #1 BRAND FED IN THE NICU
  • EXCELLENT CATCH-UP GROWTH: Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula
  • HELPS SUPPORT BRAIN & EYES: Has DHA and lutein, important components found in breast milk
  • ALSO AVAILABLE IN CONVENIENT READY TO FEED: Great for on-the-go and late-night feeding; no mixing required
  • HELPS SUPPORT BONE GROWTH: Our formula has calcium and phosphorus for baby’s growing bones

Description

Similac NeoSure* premature post-discharge baby formula promotes excellent catch-up growth1 during a premature baby’s first 12 months of life. It has enriched nutrition increased protein, vitamins, and minerals for growth compared to term infant formula—as well as calcium and phosphorus for baby’s growing bones. It has DHA and lutein to help support baby’s brain and eye development, and it has no artificial growth hormones.†
* Not for infants or children with galactosemia.
† Milk ingredients are derived from milk of non-rbST-treated cows, which is not different from milk of rbST-treated cows.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107(4):683-689.

Serving Size: 4.5 fl oz

Amount Per Serving

Calories: 100
% Daily Value*
Sodium 33mg
Chloride 75mg
Selenium 2.3mcg
Iodine 15mcg33%
Zinc 1.2mg24%
Phosphorus 62mg12%
Magnesium 9mg13%
Potassium 142mg
Iron 1.8mg12%
Calcium 105mg18%
Choline 16mg
Vitamin C 15mg43%
Biotin 9mcg18%
Folic Acid 25mcg25%
Vitamin B12 0.4mcg20%
Vitamin K 11mcg
Protein 2.8g
Total Fat 5.5g
Total Carbohydrate 10.1g
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

ingredients: nonfat milk, corn syrup solids, lactose, soy oil, high oleic safflower oil, whey protein concentrate, medium chain triglycerides, coconut oil; less than 2% of: c. cohni oil, m., alpina oil, beta-carotene, lutein, potassium citrate, calcium phosphate, inositol, ascorbic acid, magnesium chloride, soy lecithin, calcium carbonate, taurine, ferrous sulfate, choline bitartrate, choline chloride, ascorbyl palmitate, l-carnitine, potassium chloride, salt, zinc sulfate, mixed tocopherols, d-alpha-tocopheryl acetate, sodium citrate, niacinamide, potassium phosphate, calcium pantothenate, copper sulfate, vitamin a palmitate, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, folic acid, manganese sulfate, phylloquinone, biotin, sodium selenate, vitamin d3, vitamin b12, potassium hydroxide, and nucleotides (adenosine 5'-monophosphate, cytidine 5'-monophosphate, disodium guanosine 5'-monophosphate, disodium uridine 5'-monophosphate)

Allergens & Warnings:

., Warning powdered infant formulas are not sterile and may be fed to prematureinfants or infants who might have immune problems only as directed by your baby's doctor. never use a microwave to warm formula. serious burns can result
Dietary Needs: Gluten-Free, Halal, Kosher
Baby Formula Focus: Brain Development, Low Birth Weight, Eye Development, Prematurity, Growth Support
Base Ingredient: Milk
State of Readiness: Mix
Form: Powdered
Package Quantity: 1
Age Stage: Infant
TCIN: 11056281
UPC: 070074574318
Item Number (DPCI): 007-09-0037
Origin: Made in the USA or Imported
Grocery Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers. Any additional pictures are suggested servings only.
If the item details aren’t accurate or complete, we want to know about it.

Shipping details

Estimated ship dimensions: 4.69 inches length x 4.14 inches width x 4.06 inches height
Estimated ship weight: 0.981 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest. If purchased online with SNAP EBT, this item must be returned within 90 days of the date it was shipped, delivered by a Shipt shopper, or made ready for pickup. This 90-day return window is required by SNAP.
See the return policy for complete information.

Q: Why is this discontinued??

submitted by Kt852 - 7 years ago
  • A: It's not a lot of times they are just out!

    submitted byAshley566 - 6 years ago
  • A: Similac NeoSure was not discontinued, but it's possible it may have been in high demand in your area. If you don't see it on your local store shelf, you may want to ask the store manager to special order it for you. -The Similac Team

    submitted byAbbott Nutrition Team - 5 years ago
    Brand expert

Q: Does it come with measure scoop ? Is it in can?

submitted by Vir - 2 years ago
  • A: Yes! If you have additional questions please feel free to reach out to our Similac at 800-850-7677, Monday-Friday from 8:30am-5pm, ET. -The Similac Team

    submitted byAbbott Nutrition Team - 2 years ago
    Brand expert

Additional product information and recommendations

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Guests are saying

This formula is highly regarded for its effectiveness in promoting weight gain in premature infants, with many guests noting significant improvements in their baby's growth and health. While it has been beneficial for many, some guests have reported issues with gas and constipation. Overall, it is a popular choice among parents looking to support their baby's nutritional needs, especially for those who were born prematurely.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.0 out of 5 stars with 451 reviews
    easy on tummy: 2.31 out of 5
    easy to prepare: 3.97 out of 5
    quality: 3.06 out of 5
    value: 2.62 out of 5
    34% would recommend
    35 recommendations
    5 out of 5 stars
    10 July, 2026
    originally posted on similac.com
    Image

    Diaper bag must!

    [This review was collected as part of a promotion.] These were a lifesaver with a newborn! They’re a great back up to keep in the diaper bag for on the go needs as well.
    And0124
    Did you find this review helpful?
    5 out of 5 stars
    9 July, 2026
    originally posted on similac.com
    Image

    GREAT FOR WEIGHT GAIN

    [This review was collected as part of a promotion.] my kids were so tiny when they were born now they’re so big🥹
    kota06
    Did you find this review helpful?
    5 out of 5 stars
    8 July, 2026
    originally posted on similac.com
    Image

    Great product

    [This review was collected as part of a promotion.] Buy this regularly and my daughter loves it and so do I! Makes going shopping so much easier!
    Jc2703
    Did you find this review helpful?
    5 out of 5 stars
    7 July, 2026
    originally posted on similac.com
    Image

    Weight gain

    [This review was collected as part of a promotion.] This is the formula my twins were given in the NICU, so it's what I trusted once we brought them home. Most importantly, they were able to gain the weight they needed quickly, which gave us so much peace of mind. I'm thankful we found a formula that worked so well for them.
    Alex18
    Did you find this review helpful?
    5 out of 5 stars
    7 July, 2026
    originally posted on similac.com
    Image

    Helped our babies grow

    [This review was collected as part of a promotion.] The only formula I would trust for my 4lb newborn twin boys. We used this product and the powdered formula version to help our boys gain weight and after 3 months, we switched to the Pro-Total Comfort Gentle (replaced with the 360 Total Care Gentle now) to be easier on our babies’ sensitive stomachs.
    1 reply from Consumer Relations team - 14 days ago
    We would like to learn more about your experience and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 05017518 when you call.
    Twinboymom
    Did you find this review helpful?
    5 out of 5 stars
    14 January, 2026
    originally posted on similac.com
    Image

    Great Formula

    Best bang for your buck by buying the larger can. Love this formula and all the benefits it has for my baby.
    formula review
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    11 November, 2025
    originally posted on similac.com
    Image

    GREAT BRAND !

    Love this brand , helps my baby weight and she loves it n she don’t spit up
    Shawntel
    Did you find this review helpful?
    4 out of 5 stars
    23 September, 2025
    originally posted on similac.com
    Image

    grandson news

    My grandson has adjusted to the formula great. he doesn't get upset stomachs nor spits up
    formulas for small tummy
    Did you find this review helpful?
    5 out of 5 stars
    20 September, 2025
    originally posted on similac.com
    Image

    N/a

    My baby’s milk and is been amazing for him. Since birth
    JR24
    Did you find this review helpful?
    5 out of 5 stars
    21 August, 2025
    originally posted on similac.com
    Image

    Perfect for prematures

    My daughter has grown healthy and happy. This formula helped to achieve her milestones and has been very gentle to her stomach,however mild gassy.
    1 reply from Consumer Relations team - 11 months ago
    We would like to learn more about your baby's experience with NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04869767 when you call.
    Dianna
    Did you find this review helpful?
    5 out of 5 stars
    3 March, 2025
    originally posted on similac.com
    Image

    Similac Neosure milk and Similac slow flow nipples

    My son was born prematurely and had to stay in the NICU. While I developed my milk supply, I supplemented multiple feedings with Similac Neosure Ready-to-feed 2oz bottles. I purchased two 48 count cases and the single use similac slow flow nipples to continue familiarity in feedings at home. He has tripled his weight and I’m happy with this brand. I am struggling to find the 2oz bottles and would love if a representative reached out and assisted with my purchase. Traveling with those individual bottles and nipples has made traveling a breeze. Multiple fit in the diaper bag and I can carry around many days worth of feedings without the need for a refrigerator.
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    8 February, 2025
    originally posted on similac.com
    Image

    Works well for Preemie Growth

    My baby has been on neosure since birth. She was born at 33 weeks and is now caught up at 5 months. She does seem to have some trouble with gas and spits up a good bit. But overall I'm happy with her development.
    1 reply from The Consumer Relations Team team - 1 year ago
    We're glad your little one is a fan of Similac NeoSure and we would like to learn more about her experience. Please give our team a call at 800-850-7677, M-F from 8:30am-5pm, ET & reference customer# 04777804. We hope to hear from you soon!
    Audrey86
    Did you find this review helpful?
    5 out of 5 stars
    8 February, 2025
    originally posted on similac.com
    Image

    Great item

    My child loves it she is not gassey or spitting up since i switched her to the powder
    Msmeah
    Did you find this review helpful?
    3 out of 5 stars
    6 February, 2025
    originally posted on similac.com
    Image

    For my Premie

    My baby was on neosure for a short while when we came home from the hospital. We switched to 360 sensitive because neosure left him very gassy.
    1 reply from The Consumer Relations Team team - 1 year ago
    Thanks for your review!. We're glad your little one is doing well on Similac 360 Total Care Sensitive and we would like to learn more about his troubles with Similac NeoSure. Feel free to give us a call when you have a few minutes to spare: 800-850-7677, M-F from 8:30am-5pm, ET & reference customer# 04777651.
    Elle
    Did you find this review helpful?
    4 out of 5 stars
    5 February, 2025
    originally posted on similac.com
    Image

    Satisfied

    The NICU started my baby on this formula. I wanted to switch to a cheaper competitor, but two pediatricians advised to stick with Similac Neosure because my baby was doing so well on it and doubled his weight! He does seem to have a lot of gas, but I will live with it since we are relieved to hear that has grown so much and went from the 27 percentile to 49 percentile for his age group.
    1 reply from The Consumer Relations Team team - 1 year ago
    Thanks for your review! We would like to learn more about your baby's experience with Similac NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04777195 when you call.
    Anonymous1
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    28 January, 2025Verified purchase

    Pediatrician recommended!

    My infant tolerates this milk and has no digestion issues whatsoever I love it!
    Taysmommy0925
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    1 November, 2024Verified purchase

    Dont use this formula

    Don’t give this to your baby. My baby was born premature and this formula was given to her at NICU. We were sent home with the ready to feed bottles and those were good. But after that I used these cans and baby has been very fussy, vomiting, and really constipated. She even cries very loud out of nowhere and pushes a-lot. I feel so bad for her. Tomorrow I will be going to her pediatric because I cant see her in pain anymore. It’s been days since she last pooped.
    1 reply from Abbott Nutrition Team team - 2 years ago
    We would like to learn more about your baby's experience with Similac NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04736571 when you call. -The Similac Team
    Dont use
    easy on tummy: 1 out of 5
    quality: 1 out of 5
    easy to prepare: 3 out of 5
    value: 1 out of 5
    2 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    10 October, 2024

    Caused major fussiness and reflux symptoms

    First, let me lead with this formula is great for rapid weight gain for a preemie. My baby gained around 9oz a week, give or take, and caught up to a relatively “normal” newborn size around 1 month on it. But now on to the ugly. In NICU, they were using the premixed liquid Neosure, which she seemed to tolerate well, and we were sent home with the powder formula with a 24 calorie formulation (5.5oz of water to 3 scoops of formula.) For the first week or so, things were pretty good, but then I noticed that she started to sound congested, but I couldn’t get anything out of her nose. Fast forward a few weeks, we’ve had increased gassiness, fussing and refusing to sleep, and some pretty evident signs of reflux, such as several episodes of nasal reflux. We give mylicon drops like they’re going out of style and suction her nose to clear it of the backup, but overall it has not been a good experience for us as NICU/preemie parents.
    1 reply from Abbott Nutrition Team team - 2 years ago
    We would like to learn more about your baby's experience with Similac NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04724561 when you call. -The Similac Team
    Rebekah B
    quality: 3 out of 5
    value: 3 out of 5
    easy to prepare: 5 out of 5
    easy on tummy: 1 out of 5
    5 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    21 May, 2024

    Caused fussiness and constipation

    My baby was born at 34 weeks. Sent home with this formula. About a week later, he was constipated and very fussy all the time. When I switched his formula to Emfamil premie version, he was back to normal with regular bowels. I do not recommend this.
    1 reply from Abbott Nutrition Team team - 2 years ago
    We would like to learn more about your baby's experience with Similac NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04672941 when you call. -The Similac Team
    Nilda Daniela
    3 guests found this review helpful. Did you?
    4 out of 5 stars
    20 April, 2024
    originally posted on similac.com
    Image

    Great formula

    My baby was born at 34 weeks 2 days and this the only formula that has helped her gain weight she went from 4lbs to 8 in about a month
    CassieC
    6 guests found this review helpful. Did you?

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