Most formulas list acetone as the primary active ingredient. Some removers also include denatonium benzoate alongside acetone.
Some formulas add conditioning agents such as Vitamin E and grapeseed oil. Other removers list botanical extracts like eucalyptus, peach and green tea.
Manufacturers sometimes advertise activation in about 2–3 minutes, and reviewers report that certain fast-acting removers can begin lifting polish in as little as a minute.
Some product notes and reviewers mention possible tingling or a burning sensation if the remover contacts skin. Labels typically advise wiping off and rinsing with water if skin contact occurs.
Labels commonly warn to keep products out of reach of children and to avoid contact with skin, eyes and mouth. They often note flammability and potential eye irritation, state the product is for nail use only, advise rinsing with water if contact occurs and contacting a doctor if symptoms worsen, and recommend storing away from heat and sunlight.
Some removers are formulated for a specific gel system and explicitly state they are not compatible with other gel products. Other removers and reviewer reports describe formulas that work across many coatings (gels, acrylics, dips, press-ons, glitter and lacquer).