Mucus Relief Extended Release Tablets - 20ct - up&up™: Gluten-Free, Cold, Cough or Flu Treatment, 600mg Guaifenesin
Only at target
$8.99
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Guests are saying
This product has garnered mixed feedback from guests, with many praising its effectiveness in relieving congestion and sinus pressure at a lower price compared to name brands. However, recent changes in formulation and packaging have caused frustration among guests, particularly regarding the addition of coloring and difficulty in accessing the pills. Despite these concerns, many guests appreciate the value and effectiveness of the product, making it a popular choice for managing cold and allergy symptoms.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.6 out of 5 stars with 549 reviews
effectiveness: 4.3 out of 5
quality: 4.03 out of 5
value: 4.17 out of 5
70% would recommend
40 recommendations
1 out of 5 stars
Thumbs down graphic, would not recommend
15 May, 2026Verified purchase
Target you can and should do better.
poor delivery this is the condition of boxes when I opened the plastic mailer they were sent in. The pills inside seem to be okay, but its a wonder!
1 out of 5 stars
Thumbs down graphic, would not recommend
17 March, 2026Verified purchase
pills are blue
ingredients are now different. pills are BLUE
1 reply from the Product Manufacturer team - 2 months ago
We are sorry to hear about your experience with the Mucus Relief Extended Release Tablets - 20ct - up&up. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 800-719-9260 or via email by going to www.perrigo.com/contact-us and reference case number 2142351. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
Thumbs down graphic, would not recommend
15 March, 2026Verified purchase
Now has added coloring!
I have purchased this product in the past and it worked well. I mainly picked this one because it didn’t have added coloring. The recent box I purchased now has FD&C Blue #1 Aluminum Lake. Really frustrating because the listed product in the site still shows a white pill and the old ingredients list. If you are going to change the product, at least make sure the correct ingredients are listed so customers can decide to go with a different product if they are unable to consume added coloring. Very frustrating.
1 reply from the Product Manufacturer team - 2 months ago
We are sorry to hear about your experience with the Up & Up Mucus Relief Extended Release Tablets product. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 1-800-719-9260 or via email by going to www.perrigo.com/contact-us and reference case number 2141179. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
30 December, 2025
False representation in product listing - contains dye
I selected this specific product when placing an order because the item listing on the Target app showed photos of white tablets and a box where the ingredients list did not contain any dye. However, the product I received is blue tablets and the box lists an inactive ingredient of FD&C blue #1 aluminum lake.
1 reply from the Product Manufacturer team - 5 months ago
We are sorry to hear about your experience with the Up & Up Mucus Relief. As the manufacturer, we cannot control the product listing on Target's site but understand your concerns with the ingredients. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2116193. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
17 December, 2025Verified purchase
(no review title)
Tried them out three times while I’ve been sick hasn’t done anything for my congestion at all
1 reply from the Product Manufacturer team - 5 months ago
We are sorry to hear about your experience with the Up & Up Mucus Relief. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2113218. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
21 November, 2025Verified purchase
Added blue coloring
I used to like this stuff. Just got a new box and the white pills now have Blue lake aluminum #1 for no reason. I bought them before because they didn’t have the added chemical and now they do. So disappointing. I am returning.
1 reply from the Product Manufacturer team - 6 months ago
We are sorry to hear about your experience with the Up & Up Mucus Relief Tablets. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2105015. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
Thumbs down graphic, would not recommend
2 November, 2025Verified purchase
Blister Packaging is a Problem.
The product is good, but the packaging is a problem. I cannot get the pills out of the blister packs, so I had to throw them away and get the brand-name Mucinex. Very disappointed as the Up&Up brand is less expensive.
1 reply from the Product Manufacturer team - 7 months ago
We are sorry to hear about your experience with the packaging of the Up & Up Mucus Relief. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2098265. We look forward to addressing your concerns and hearing from you!
5 out of 5 stars
Thumbs up graphic, would recommend
26 March, 2025Verified purchase
Medicine cabinet staple!
Great value and effective!
4 out of 5 stars
Thumbs up graphic, would recommend
3 March, 2025Verified purchase
Cant live without!
these help congestion and sinus headaches.
1 out of 5 stars
Thumbs down graphic, would not recommend
3 February, 2025Verified purchase
Doesn’t. Explain. Ineffectiveness.
Poor quality product. Not effective.
3 out of 5 stars
Thumbs down graphic, would not recommend
13 January, 2025
Try vicks sinex spray instead
It didn't clear up my congestion completely, but also didn't give me any weird side effects like the extra strength does. I will use up the rest important my next flu/cold but I won't be purchasing again. Vicks sinex spray did the job for me.
1 out of 5 stars
Thumbs down graphic, would not recommend
31 October, 2024Verified purchase
Concerning inactive ingredient
I believe this contains the carcinogen “carbomer”, so we threw ours out. See https://www.npr.org/2024/08/16/nx-s1-5077764/millions-of-americans-may-be-getting-cancer-causing-chemical-in-generic-cold-medicine.
5 out of 5 stars
Thumbs up graphic, would recommend
11 October, 2024
Works great
Great generic brand compared to name brand.
1 out of 5 stars
Thumbs down graphic, would not recommend
10 October, 2024Verified purchase
Difficult bubble srap
I have been getting this product for years. My original review concerned the wasteful product container. I could get (easily) two bottles into one. Now my issue is the bubble wrap of the pills, I am almost 70 years old and this product is very difficult to push through! I am considering a different product that is more user friendly😔😔
1 out of 5 stars
Thumbs down graphic, would not recommend
30 September, 2024Verified purchase
New box but does not work
New formulation doesn’t work! The pills that came in the bottle were great, as all of these reviews state, prior to September 2024. Now, same brand, same generic, same price, but in a blister pack with a different color pill. Doesn’t work at all. Please bring back the prior pills in a bottle.
5 out of 5 stars
Thumbs up graphic, would recommend
5 August, 2024Verified purchase
Very good for sticky sinuses
These work well but drink the recommended water.
1 out of 5 stars
Thumbs down graphic, would not recommend
26 July, 2024Verified purchase
Mucus relief
This item did not relieve any pressure or release the mucus buildup.
4 out of 5 stars
Thumbs up graphic, would recommend
5 June, 2024Verified purchase
Good generic alternative
Don't buy the name brand stuff if you don't have to. This is the same! This recently helped me knock out a case of sinusitits before it required antibiotics. I always buy this one or the one with the cough suppressant as well. If you are prone to sinus infections and your doctor recommends the name brand use this instead. The only downside is it tastes awful when you swallow it and the pill is pretty large.
5 out of 5 stars
Thumbs up graphic, would recommend
9 April, 2024Verified purchase
Helped me a lot
I couldn’t get phlegm out of my throat for weeks until I started taking this daily. Helped me a lot!
5 out of 5 stars
Thumbs up graphic, would recommend
6 April, 2024Verified purchase
Better than other big store brand
Better than competition store brand in freshness and effectiveness