Fluticasone Propionate Allergy Relief Nasal Spray - 72 sprays/0.38 fl oz - up&up™
Only at target
$9.89 ($26.03/fluid ounce)
Pack Size0.38 fl oz
In Stock
Eligible for registries and wish lists
At a glance
About this item
Additional product information and recommendations
Discover more options
- Highly rated$17.49 - $46.99$5 Target GiftCard with 2 select allergy relief tablets4.7 out of 5 stars with 2525 ratings
- $14.19($24.89/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4.6 out of 5 stars with 247 ratings
- Highly rated$17.49 - $46.99$5 Target GiftCard with 2 select allergy relief tablets4.6 out of 5 stars with 2099 ratings
- $17.49($51.44/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4.8 out of 5 stars with 288 ratings
- $14.29$5 Target GiftCard with 2 select allergy relief tablets4.4 out of 5 stars with 242 ratings
- $9.49 - $16.49$5 Target GiftCard with 2 select allergy relief tablets on select items4.7 out of 5 stars with 874 ratings
- $15.29($41.32/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4 out of 5 stars with 4567 ratings
- $17.49($87.45/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4.8 out of 5 stars with 971 ratings
- $10.19($13.59/fluid ounce)Buy 1 get 1 20% off select Mucinex medicines4.3 out of 5 stars with 714 ratings
- $13.99($13.99/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4.8 out of 5 stars with 846 ratings
- Highly rated$13.99 - $29.99$5 Target GiftCard with 2 select allergy relief tablets4.6 out of 5 stars with 1875 ratings
- $24.49$5 Target GiftCard with 2 select allergy relief tablets4 out of 5 stars with 4497 ratings
- $9.99 - $16.99$5 Target GiftCard with 2 select allergy relief tablets4.6 out of 5 stars with 344 ratings
- $10.99($1.37/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4.8 out of 5 stars with 786 ratings
Frequently bought together
Guests also viewed
- Highly rated$17.49 - $46.99$5 Target GiftCard with 2 select allergy relief tablets4.7 out of 5 stars with 2525 ratings
- $15.29($41.32/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4 out of 5 stars with 4567 ratings
- $17.49($87.45/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4.8 out of 5 stars with 971 ratings
- $14.19($24.89/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4.6 out of 5 stars with 247 ratings
- $10.99($1.37/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4.8 out of 5 stars with 786 ratings
- Highly rated$17.49 - $46.99$5 Target GiftCard with 2 select allergy relief tablets4.6 out of 5 stars with 2099 ratings
- $17.49($51.44/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4.8 out of 5 stars with 288 ratings
- $13.99($13.99/fluid ounce)$5 Target GiftCard with 2 select allergy relief tablets4.8 out of 5 stars with 846 ratings
- Highly rated$13.99 - $29.99$5 Target GiftCard with 2 select allergy relief tablets4.6 out of 5 stars with 1875 ratings
- $14.29$5 Target GiftCard with 2 select allergy relief tablets4.4 out of 5 stars with 242 ratings
- $9.39($55.24/fluid ounce)4.5 out of 5 stars with 923 ratings
Related Categories
Guests are saying
This nasal spray offers effective relief for allergy sufferers, providing results comparable to the name brand at a more affordable price. Many guests appreciate its ability to clear nasal congestion and alleviate allergy symptoms, making it a daily essential for those with seasonal allergies. However, some guests have noted issues with the pump design and taste. Overall, it is a reliable choice for guests looking to save money without sacrificing quality.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.7 out of 5 stars with 2349 reviews
effectiveness: 4.61 out of 5
quality: 4.62 out of 5
value: 4.44 out of 5
85% would recommend
105 recommendations
5 out of 5 stars
15 April, 2026Verified purchase
(no review title)
This allergy spray works very well on nasal allergies.
5 out of 5 stars
29 March, 2026
Instruction sheet says doctors have prescribed for 20+ years
Excellent instruction sheet. Informative, and easy to read.
5 out of 5 stars
21 March, 2026Verified purchase
Works!
Easy to use works efficiently
5 out of 5 stars
Thumbs up graphic, would recommend
14 March, 2026Verified purchase
allergy helper
helps with breakthrough allergy stuffiness. It is not a total decongestant like Afrin, but does help in addition to allergy meds for mild stuffiness and itchiness. As good as Flonase
5 out of 5 stars
22 February, 2026Verified purchase
Target rocks
Good job Target
5 out of 5 stars
Thumbs up graphic, would recommend
18 January, 2026Verified purchase
Great Value
Great value especially if use regularly or have multiple family members.
5 out of 5 stars
Thumbs up graphic, would recommend
9 October, 2025Verified purchase
Great product!
I have bad allergies, been using this for 10+ years. Keeps me from itching my nose constantly.
1 out of 5 stars
Thumbs down graphic, would not recommend
2 October, 2025
Shameful Price Gauging of Generic Medicine
This store brand generic is overpriced by about 80%. I advise purchasing elsewhere. The savings is too much to overlook
1 out of 5 stars
Thumbs down graphic, would not recommend
30 September, 2025Verified purchase
Misleading
Not even half full!!!!
1 reply from the Product Manufacturer team - 8 months ago
We are sorry to hear about your experience with the Up & Up Nasal Spray. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2088187. We look forward to addressing your concerns and hearing from you!
5 out of 5 stars
Thumbs up graphic, would recommend
21 August, 2025
Same As Flonase
Same as Flonase but cheaper. I will continue to purchase.
5 out of 5 stars
Thumbs up graphic, would recommend
3 August, 2025
originally posted on Sozie

Amazing value - an allergy family's must have!
[This review was collected as part of a promotion.] I was thrilled that this four pack was offered! There are three of us in the house who suffer from allergies and name brand products become expensive. My son used this and didn't notice a difference from his other name brand medication. It's easy to open and easy to close, and had the same medication as his other name brand pump at a fraction of the cost. Great purchase! I received an incentive to write this review.
5 out of 5 stars
Thumbs up graphic, would recommend
1 August, 2025
originally posted on Sozie

Perfect nasal spray for allergy relief!
[This review was collected as part of a promotion.] I purchased this for my household because we all suffer from seasonal allergies. I typically will use an allergy pill along with a nasal spray. This spray definitely provided relief. It is very easy to use and comparable to a well known name brand product. I love that it comes with 4 bottles so everyone in my family can each have their own. This nasal spray is non drowsy and at full prescription strength! I received an incentive to write this review.
5 out of 5 stars
Thumbs up graphic, would recommend
22 July, 2025
originally posted on Sozie

Effective and affordable nasal spray
[This review was collected as part of a promotion.] I’ve been using this product for a couple of years based on when my allergies hit. I really see no difference between this and what a doctor would prescribe. I’ve never questioned. It’s effectiveness and it’s ability to do the job that it’s prescribed to do I did like that. It came in a four pack because it made price more affordable versus just buying one at a time. I received an incentive to write this review.
5 out of 5 stars
Thumbs up graphic, would recommend
19 July, 2025
originally posted on Sozie

Have allergies? You need this!
[This review was collected as part of a promotion.] The Up and Up full prescription strength Fluticasone nasal spray is the go to in our family when it’s allergy season in the south, which pretty means year round. We like the 4 pack because it’s a little more inexpensive than buying individual bottles and because we have a big family, this helps. We stopped using the name brand because the up and up version works the same for us. I received an incentive to write this review.
5 out of 5 stars
Thumbs up graphic, would recommend
17 July, 2025
originally posted on Sozie

Allergy Relief Nasal Spray Box of Four
[This review was collected as part of a promotion.] This allergy spray by up&up is an excellent value. It has four bottles in the box and up to 576 sprays. This will last me a really long time. My doctor always recommends doing an allergy nasal spray for my seasonal allergies along with a pill and I think it really does help with my congestion. The bottles are easy to use and the spray is really strong. I would highly recommend this product if you need a nasal spray. I received an incentive to write this review.
5 out of 5 stars
Thumbs up graphic, would recommend
11 July, 2025Verified purchase
Worked better than the name brand
This works as well as the name brand and costs much less. I also have no side effects from this generic brand, however, I do from the name brand.
5 out of 5 stars
Thumbs up graphic, would recommend
6 July, 2025Verified purchase
Good deal
Seems to work just as well as the name brand Flonase. Good price.
4 out of 5 stars
Thumbs up graphic, would recommend
27 June, 2025Verified purchase
works well
Medication is same ingredient as flonase. The pump needs to be primed often when running low so I'm not sure it's contains the number of sprays as advertised but it's a more affordable option than the brand name per spray
5 out of 5 stars
Thumbs up graphic, would recommend
8 June, 2025Verified purchase
Breath again!
Does the job! Better than name brand products
5 out of 5 stars
Thumbs up graphic, would recommend
6 April, 2025Verified purchase
It works
This helps so much with my allergies and breathing