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Day and Night Severe Cold & Flu Medicine Liquid - Honey - 24 fl oz - up&up™ - 2 of 4Day and Night Severe Cold & Flu Medicine Liquid - Honey - 24 fl oz - up&up™ - 3 of 4Day and Night Severe Cold & Flu Medicine Liquid - Honey - 24 fl oz - up&up™ - 4 of 4
Day and Night Severe Cold & Flu Medicine Liquid - Honey - 24 fl oz - up&up™ - 1 of 4

Day and Night Severe Cold & Flu Medicine Liquid - Honey - 24 fl oz - up&up™

$11.69 ($0.49/fluid ounce)

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At a glance

About this item

Highlights

  • Honey-flavor day and night medicine for severe cold and flu
  • Active ingredient acetaminophen
  • Suggested for 12+ years
  • 24fl oz

Description

Provide your family with relief from cold and flu symptoms with the Day and Night Severe Cold and Flu Medicine from up&up™. This day and night medicine for severe cold and flu has a honey flavor for a great taste. Made with acetaminophen as the active ingredient, it helps provide relief from fever, congestion and other cold and flu symptoms.

up&up™: We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Suggested Age: 12 Years and Up
Health Facts: Contains Doxylamine Succinate, Contains Acetaminophen, Contains Dextromethorphan, Contains Guaifenesin, Contains Phenylephrine HCI
Product Warning: Keep out of reach of children, Contains Acetaminophen, not for children under the age of 12, consult a doctor if you have glaucoma, ask a doctor if you have prostate issues, do not use if you are taking an MAOI, consult a doctor if you have urination issues
Active Ingredient Strength Value: 325 Milligrams
Product Form: Liquid
Primary Active Ingredient: Acetaminophen
Package Quantity: 1
Net weight: 24 fl oz (US)
Features: Daytime and Nighttime Use
TCIN: 90515918
UPC: 311673328026
Item Number (DPCI): 094-14-0929
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Shipping details

Estimated ship dimensions: 5.3 inches length x 2.2 inches width x 6.8 inches height
Estimated ship weight: 1.9 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Additional product information and recommendations

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Guests are saying

This cold and flu medicine offers a convenient day and night solution, making it easier for guests to manage their symptoms effectively. The daytime formula helps maintain productivity while feeling unwell, and the nighttime version promotes restful sleep. Many guests appreciate the smooth flavor and fast-acting relief, although some have noted taste and effectiveness issues. Overall, it is a practical choice for those battling seasonal illnesses.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.5 out of 5 stars with 58 reviews
    66% would recommend
    6 recommendations
    5 out of 5 stars
    14 January, 2026Verified purchase

    (no review title)

    This cold and flu season has been going on and these two products are the only reason I can function!
    Karla
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    28 November, 2025Verified purchase

    worked great

    It worked great! The night time made me sleep thru the night. Going to go buy more for my family they are all sick.
    AJ
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    2 out of 5 stars
    14 November, 2025

    Not compared to nyquil

    The nighttime cold and flu one is literally nondrowsy and does nothing for me. It doesn’t help with any of my symptoms and doesn’t help put me to sleep.
    Lauren
    Did you find this review helpful?
    3 out of 5 stars
    Thumbs up graphic, would recommend
    24 December, 2024Verified purchase

    Where's the Honey?

    Does the job but wow does it taste nothing at all like honey. Same old cold medicine taste.
    Jay
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    19 December, 2024

    Nope

    It tastes nothing like honey. My throat burns after taking it and it seems to tricker an acid reflux. This product is made in India, compared to the other brands that are made in Canada or the US. My symptoms did not improve after taking it.
    WHATT
    1 guest found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    12 December, 2024

    Did not work for me

    This medicine actually gave me a headache and made me want to vomit right after. I’m not sure why that is but definitely will not be using again.
    Thankmelater
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    24 November, 2024

    Day & Night Relief

    The Day and Night Severe Cold & Flu Medicine Liquid - Honey flavored is the perfect combination of day and night cold and flu medicine. The main ingredient is acetaminophen, so this is not recommended for kids under the age of 12. I use the daytime formula during the days when I need to get things done, even though I don't feel well. The nighttime formula is perfect when you need to get a good night's sleep. This helps with nasal congestion, sinus pressure, cough, and more. The flavor is tasteful and smooth, and this is fast acting. I highly recommend this cold and flu medicine!
    ksb38020
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    22 November, 2024

    Excellent

    This stuff is great. I love how there are 2 bottles. One for day time and one for night. Even for an off brand, it works excellent. It doesnt taste bad at all. The liquid option is perfect for anyone. It definitely is worth the price.
    Mommabear04
    Did you find this review helpful?

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