First Aid Antibiotic Pain Relieving Cream - 0.5oz - up&up™
$2.29
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4.8 out of 5 stars with 306 reviews
quality: 4.33 out of 5
value: 4.25 out of 5
90% would recommend
20 recommendations
1 out of 5 stars
Thumbs down graphic, would not recommend
15 February, 2026
Made my wound worse
My wound refused to heal when using this. When I switched to another brand (with bacitracin), it healed in a day. Also, didn't help with the pain for more than 10 minutes.
2 out of 5 stars
27 January, 2026
impossible to open
impossible to open… i literally haven’t even tried it yet but i’ve spent 15 minutes trying to get it open….
1 out of 5 stars
Thumbs down graphic, would not recommend
17 January, 2026Verified purchase
Gave me a rash
Gave me a rash on my face after using it for a burn that I got. Now the entire area of the burn looks red and bumpy and inflamed. I put that on to help it to heal and instead it made it worse. 😢
5 out of 5 stars
Thumbs up graphic, would recommend
19 July, 2025Verified purchase
Creamy white soothing antibacterial cream
Injured my arm a week ago. It's still healing. Was a bit swollen but this cream has seemed to take that down a notch. Also have been wrapping my arm in gauze which made my arm itch like crazy and this definitely helped that. Just FYI, it's a creamy white cream when spreading. Not clear or invisible. I don't care because I just want my arm to heal minus a doctor's visit!
5 out of 5 stars
Thumbs up graphic, would recommend
16 February, 2025Verified purchase
Works better than the name brands!
We always purchase Up&Up products to compare then to other name brands. This is a staple in our home now. It works!
5 out of 5 stars
Thumbs up graphic, would recommend
29 December, 2024Verified purchase
Good item
Affordable and good quality.
5 out of 5 stars
Thumbs up graphic, would recommend
4 October, 2024Verified purchase
Just like the name brand
I feel like this product works just like the "name Brand".
5 out of 5 stars
Thumbs up graphic, would recommend
18 September, 2024Verified purchase
Works great.
I bought this for my first aid kit to keep in my car & it is great! I found it while looking for the brand name Neosporin & used it on a cut on my thumb that was sore & getting swollen. By the end of the day it was totally cleared up, no longer sore, and healing well!
5 out of 5 stars
Thumbs up graphic, would recommend
7 August, 2024Verified purchase
Works better than the name brand
Better than expected 10/10. No smell, no greasy residue, just put on the cut or burn and you feel it working instantly. I pruned the palm of my hand cooking and it was throbbing and stinging really bad afterwards that no amount of icing helped. I bought this and put it on the burn and it worked instantly and the redness has gone down tremendously and no more pain.
5 out of 5 stars
Thumbs up graphic, would recommend
30 July, 2024Verified purchase
Love This!!
This prevented scarring, and quickly! Can't wait to repurchase! Better than name-brand ointment style. I promise.
5 out of 5 stars
Thumbs up graphic, would recommend
27 July, 2024
First Aid Staple!
This cream worked just as well as the name brand cream out there. The applicator is the same you would fine on any other - making it east to apply to the area you want. It is odorless. Easy to store in any first aid nag, purse, etc.
5 out of 5 stars
Thumbs up graphic, would recommend
27 June, 2024Verified purchase
would recommend just as good as namebrand
I used this for a little cut on my pinky toe that may have been athletes foot. It healed the cut with no problem in about four days. The applicators really nice and a little goes a long way. Highly recommend.
5 out of 5 stars
Thumbs up graphic, would recommend
20 June, 2024Verified purchase
Antibiotic ointment
I’ve purchased this product previously and it worked just as it should so I’ve purchased it again.
5 out of 5 stars
Thumbs up graphic, would recommend
9 June, 2024
Soothing and pain relieving. - As expected
This cream is easy to apply and a little goes a long way with this. It provides a good soothing feeling and helps to relieve pain or all those scraps and cuts. This is odorless as well. The tube is easy to store and bring along as needed.
5 out of 5 stars
Thumbs up graphic, would recommend
9 June, 2024
Great product
This product works well at a fraction of the cost of a brand name. I like that this includes a pain reliever in addition to the antibiotic, sometimes you need that for bad cuts and scrapes. A must have in my medicine cabinet!
4 out of 5 stars
Thumbs up graphic, would recommend
6 June, 2024
Great ointment
We have grown to love this over the leading brands. It’s very healing and a little goes a long way. Was it being summertime there will be a lot of playing for the kids and getting hurt is definitely number one on the list. Having this in my purse at all times definitely keeps me prepared
5 out of 5 stars
Thumbs up graphic, would recommend
26 May, 2024Verified purchase
Glad to have it
Effective, better than an ointment, and a really good price at under $3! Very happy with Up & Up version of neosporin cream (the name brand is over $9 now?!)
5 out of 5 stars
Thumbs up graphic, would recommend
24 May, 2024
Summer staple!
We use this medication so many times especially thru the summer. It treats cuts and scrapes plus it has a built-in pain relief product and infection protection, what else could you ask for. We keep several tubes of this.
5 out of 5 stars
Thumbs up graphic, would recommend
23 May, 2024
Soothing Relief and Protection in Every Application
I received these products for free from the Hey, Bullseye™ sampling program in exchange for my honest review. I’ve found the perfect ally for my family’s first aid kit: the First Aid Antibiotic Pain Relieving Cream by up & up. This 0.5oz tube is a compact yet powerful solution for those unexpected minor injuries that need immediate attention. The cream’s maximum-strength pain relief is evident from the first application, thanks to the neomycin and pramoxine hydrochloride in its formula. It not only soothes the pain but also significantly reduces the discomfort associated with minor cuts, scrapes, and burns. What I love most about this product is its dual-action capability. It doesn’t just offer pain relief; it also helps prevent infections. The neomycin works as a first aid antibiotic, ensuring that my minor wounds are protected against bacteria, which is essential for a speedy recovery. The cream is easy to apply, and its non-greasy formula means it absorbs quickly without leaving any residue. I can apply a small amount and be confident that it’s working to heal and protect my skin. Moreover, the up & up brand continues to impress me with its commitment to quality and affordability. This cream is a testament to their promise of providing healthcare solutions that are accessible to everyone. In conclusion, the First Aid Antibiotic Pain Relieving Cream by up & up is a standout product that delivers on its promises. It’s the peace of mind in a tube that I trust for myself and my family. I highly recommend it to anyone looking for an effective and reliable first aid solution.
5 out of 5 stars
Thumbs up graphic, would recommend
20 May, 2024
A staple in my first aid kit! Great quality, doesn’t break the bank and provides the same relief as the competitor.
The Up&Up Maximum Strength Pain Relieving & Infection Protection surpasses the name brand version. Both quality and affordability, makes it a top pick for my first aid kit. The cream goes on smooth and doesn’t make a mess. Doesn’t burn when applied to a scrape and offers immediate pain relief.