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Murad Biome-Balancing Acne Serum - Ulta Beauty: Paraben-Free, Sulfate-Free, Alcohol-Free, For Normal, Oily & Combination Skin - 2 of 4Murad Biome-Balancing Acne Serum - Ulta Beauty: Paraben-Free, Sulfate-Free, Alcohol-Free, For Normal, Oily & Combination Skin - 3 of 4Murad Biome-Balancing Acne Serum - Ulta Beauty: Paraben-Free, Sulfate-Free, Alcohol-Free, For Normal, Oily & Combination Skin - 4 of 4
Murad Biome-Balancing Acne Serum - Ulta Beauty: Paraben-Free, Sulfate-Free, Alcohol-Free, For Normal, Oily & Combination Skin - 1 of 4

Murad Biome-Balancing Acne Serum - Ulta Beauty: Paraben-Free, Sulfate-Free, Alcohol-Free, For Normal, Oily & Combination Skin

$45.00

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At a glance

About this item

Highlights

  • Clinically proven to help clear active breakouts starting in just 3 days
  • Biome-Sensing Tech encourages a healthier, more balanced microbiome that's naturally more resistant to future breakouts
  • Clears all types of acne, including whiteheads, blackheads, and hormonal breakouts
  • Non-comedogenic, non-drying, non-irritating, layers well under makeup, no pilling or flaking, gentle enough for daily use
  • Cruelty-free

Description

Murad's Biome-Balancing Clear & Prevent Acne Treatment Serum starts to clear acne in just 3 days, helps prevent breakouts and empowers your biome to thrive for healthier-looking skin.

Key Ingredients:
• Mandelic Acid: an alpha-hydroxy acid (AHA) used to smooth and even the complexion
• Biome-Sensing Tech: encourages a healthier, more balanced microbiome that's naturally more resistant to future breakouts
• Medicated Salicylic Acid: clears and prevents acne, and penetrates deep to decongest clogged pores
• Glutamic Acid: "feeds" the skin's microbiome so it produces GABA, a protective amino acid for healthier-looking, smoother skin

Clinical Results:
• Clearer skin starts in just 3 days*
• Clinically proven to reduce active breakouts, and improve skin health and clarity*
• 92% agree: no unwanted side effects* including peeling, flaking, redness, and irritation
• *Consumer testing on 26 subjects in a 4-week study
• *Expert grading of photos on 26 subjects in a 4-week study

How To Use:
AM and PM. Cleanse, tone, then apply 1-2 pumps to face and neck, allowing serum to fully absorb before applying moisturizer or SPF during the day. Deep acne bump or breakout? Alternate by applying Biome-Balancing Clear & Prevent Acne Treatment Serum during the day, and spot-treating with Deep Relief Acne Treatment at night.
Scent: Unscented
Health Facts: Mineral Oil-Free, Sulfate-Free, Gluten-Free, Formaldehyde-Free, Oxybenzone-Free, Alcohol-Free, Paraben-Free, Sodium Lauryl Sulfate-Free, Phthalate-Free
Product Warning: Keep out of reach of children
Product Form: Serum
Beauty Purpose: Pore Cleansing, Smoothing, Anti-Acne, Skin Tone Improvement
Recommended Skin Type: Combination, Oily, Normal, Acne-Prone
TCIN: 94736784
UPC: 767332150369
Item Number (DPCI): 342-01-8408
Origin: Made in the USA
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

salicylic acid' '1.0%

Purpose

Acne Treatment

Uses

Use for the management of acne

Directions

Directions clean the skin thoroughly before applying product, cover the entire affected area with a thin layer one to three times daily, because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor, if bothersome dryness or peeling occurs, reduce application to once a day or every other day

Other information

Other information store at room temperature, avoid high temperatures, protect from freezing, keep away from flame, fire and heat

Inactive ingredients

water (aqua), propanediol, mandelic acid, glycerin, erythritol, pentylene glycol, sodium polyacryloyldimethyl taurate, dimethicone, sodium hydroxide, saccharide isomerate, glutamic acid, allantoin, punica granatum pericarp extract, nelumbo nucifera flower extract, nymphaea caerulea flower extract, urea, yeast amino acids, trehalose, inositol, taurine, betaine, melia azadirachta leaf extract, melia azadirachta flower extract, corallina officinalis extract, coccinia indica fruit extract, aloe barbadensis flower extract, solanum melongena (eggplant) fruit extract, ocimum basilicum (basil) flower/leaf extract, curcuma longa (turmeric) root extract, ocimum sanctum leaf extract, maltodextrin, glyceryl polyacrylate, polysilicone-11, butylene glycol, decyl glucoside, tetrasodium glutamate diacetate, citric acid, sodium citrate, 1,2-hexanediol, leuconostoc/radish root ferment filtrate, caprylyl glycol, chlorphenesin

Shipping details

Estimated ship dimensions: 1.531 inches length x 1.531 inches width x 4.563 inches height
Estimated ship weight: 0.185 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Additional product information and recommendations

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Guests are saying

This serum is highly praised for its effectiveness in treating acne and preventing breakouts, making it a valuable addition to any skincare routine. Guests appreciate its lightweight, gel-like texture that absorbs quickly without leaving a sticky residue. The combination of salicylic and mandelic acids helps clear clogged pores while being gentle on the skin. Many guests report visible improvements in their skin's clarity and texture within days of use, making it a reliable choice for those with acne-prone skin.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.7 out of 5 stars with 177 reviews
    5 out of 5 stars
    4 April, 2026
    originally posted on http://www.ulta.com
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    love it!

    this is the only serum that helps me with my closed comodones/ whiteheads. My cheeks usually are covered in them but once I incorporated this into my routine they disappeared after 3 days! I just wish it was cheaper to buy.
    rye
    Did you find this review helpful?
    5 out of 5 stars
    14 March, 2026
    originally posted on http://www.ulta.com
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    Saved me MULTIPLE times

    I run to this product whenever I start to feel a breakout coming or even if one has already started and even though it has actives it calms down my extremely reactive skin. I suffer from getting breakouts during my luteal phase and this has saved me multiple times. The only thing I will say is that if you get post-inflammatory erythema, which I do, I would add a brightening serum or something else since this has helped with clearing my skin but it takes a VERY long time to help PIE. Overall, I have bought countless bottles, and will continue to as backups!
    Mary
    Did you find this review helpful?
    5 out of 5 stars
    9 March, 2026
    originally posted on http://www.ulta.com
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    Great for acne-prone skin

    [I received this product in exchange for my honest review] This is a nice serum for those with acne-prone skin who wish to have a little more control over their breakouts. It's not a miracle serum, since acne can occur for multiple reasons, but it's very helpful. The ingredients are great. This serum has a gel-like consistency and no scent. It doesn't sting or irritate the skin in any way, which is surprising for an acne product. I like that it has a pump, but the plastic packaging feels cheap for a $45 product.
    Agnes
    Did you find this review helpful?
    5 out of 5 stars
    19 February, 2026
    originally posted on http://www.ulta.com
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    Acne control without harsh irritation

    I really like this serum. It's lightweight, absorbs quickly, and doesn't feel sticky. It helps calm breakouts without drying out my skin. My skin feels more balanced and smoother overall. Great option if you want acne control without harsh irritation. I would repurchase.
    Dia
    Did you find this review helpful?
    5 out of 5 stars
    15 February, 2026
    originally posted on http://www.ulta.com
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    Please buy this!

    Okay I have never written a review before but I feel like I need to for this product/brand. I was struggling with inflammed, painful, acne under my skin that never came to the surface for a whole year. Since i started using Murad, it has stopped. Idk what they put in their products but i'll never go back to anyone else. I did a lot of research and everything told me that i need to heal my gut. My new daily routine is taking Olly's womens multi (for gut health) then the biome balancing acne treatment serum and their environmental shield rapid dark spot correcting serum. Ive been doing this for the last 4-6 months and my acne is gone.
    Liv
    Did you find this review helpful?
    5 out of 5 stars
    15 January, 2026
    originally posted on http://www.ulta.com
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    holy grail ??

    i swear this stuff cleared up my stubborn closed comedones especially on my forehead. now my forehead is so smooth after dealing with the comedones for years FINALLY. as for active pimples, it does clear them up but don't expect overnight results. it also helps with the redness and bumpyness of pimples too. overall a good product!
    alexandra
    Did you find this review helpful?
    3 out of 5 stars
    2 January, 2026
    originally posted on http://www.ulta.com
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    Not so great

    [I received this product in exchange for my honest review] It only worked a lil bit while I was using it. Go this serum and I had my sister trying it out. Once she ran out of the serum she immediately started breaking out again, she's not so sure she will be giving this serum another try .
    Lucero V
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    17 October, 2025
    originally posted on http://www.ulta.com
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    Amazinggg

    [I received this product in exchange for my honest review] This brand has given me much better results than others I've tried. I personally love this packaging and I love the ease of use that it has. This is something I've bought for my family before and I give to them on holidays because everyone deserves beautiful skin.
    Jill
    Did you find this review helpful?
    5 out of 5 stars
    7 October, 2025
    originally posted on http://www.ulta.com
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    Great

    [I received this product in exchange for my honest review] This acne spot treatment saves the day every time! I didn't know what to expect was it the product itself but let me say it works wonders! I put the treatment on at night and by morning it has cleared most of the way. I know because of the clean ingredients! What i see it does is it dries the acne spot out and heals the barrier of the skin! Gets rid of redness also! It does not have a smell. The packaging is top notch!
    Blakely
    Did you find this review helpful?
    5 out of 5 stars
    27 September, 2025
    originally posted on http://www.ulta.com
    Image

    A must!!

    Lately my skin it's been very clear but a few days ago I had a few pimples on my cheeks and I used a little bit of this serum and helped me a lot with that!! It was very impress cause it didn't irritate me at all or make me dry patches… it's a very gentle and functional quick treatment for acne (at least a very mild acne) the packaging it's very ergonomic and works really great!
    Dayana
    Did you find this review helpful?
    5 out of 5 stars
    10 August, 2025
    originally posted on http://www.ulta.com
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    My new skincare 🤍

    I received this product in exchange for my honest review. I've been trying out the Murad Biome Balancing Clear & Prevent Acne Treatment Serum and I'm so impressed. With 1% salicylic acid and mandelic acid, it's gentle yet effective, smoothing texture, calming breakouts, and keeping my skin balanced without over-drying. The lightweight formula absorbs instantly, making it perfect for both AM & PM routines. If you're looking for clearer, healthier-looking skin, this one's worth the hype⭐️
    Kristine
    Did you find this review helpful?
    5 out of 5 stars
    8 August, 2025
    originally posted on http://www.ulta.com
    Image

    Super hydrating!!

    [I received this product in exchange for my honest review] This treatment is very a very gentle way to get my skin hydrated without my acne flaring up or getting new acne spots. It doesn't have a scent and has ingredients that will keep my skin hydrated without damaging it.
    Amanda
    Did you find this review helpful?
    5 out of 5 stars
    1 August, 2025
    originally posted on http://www.ulta.com
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    Must have

    [I received this product in exchange for my honest review] I used a couple days i will keep update but when i check the ingredients looks good. Packaging was good and arrived safe. Smells good I love Murad already
    Cindy
    Did you find this review helpful?
    5 out of 5 stars
    30 July, 2025
    originally posted on http://www.ulta.com
    Image

    Great serum

    [I received this product in exchange for my honest review] This serum is great for acne prone skin! I tend to have hormonal acne and this is great at keeping the acne less inflamed. I love that it apples easy on the skin and doesn't have a scent. I highly recommend it! The packing is in pump form and dispenses a good amount of product!
    Rocio R
    Did you find this review helpful?
    3 out of 5 stars
    23 July, 2025
    originally posted on http://www.ulta.com
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    Sinks into the skin fast! And no scent!

    [I received this product in exchange for my honest review] The texture is like a water gel that sinks into the skin pretty fast. I haven't noticed a scent so that's a plus! I can't say that it has done much for my skin but I haven't had it very long.
    Jordan
    Did you find this review helpful?
    5 out of 5 stars
    14 July, 2025
    originally posted on http://www.ulta.com
    Image

    Love it

    I've been using the Murad Biome-Balancing Clear & Prevent Acne Treatment Serum for a couple of weeks now, and I'm honestly impressed. The texture is lightweight and gel-like — it absorbs quickly and doesn't leave any sticky residue. One of the best things about it is that it treats breakouts without drying out my skin, which is rare for acne products. I noticed that active pimples calm down faster, and my skin looks less inflamed and red. It didn't cause any purging or new breakouts, and over time, my skin feels more balanced — less oily in the T-zone, but still hydrated.
    Daniela
    Did you find this review helpful?
    5 out of 5 stars
    14 July, 2025
    originally posted on http://www.ulta.com
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    Finally, A Product That Works

    This product is the first effective treatment I have found for my problem: blocked pores. I had bumps that would sit for months, mainly on my chin and around my mouth, and whatever I tried dried out and often irritated my skin but the bumps remained. The serum empties clogged pores but is also kind to your skin.
    Dusty
    Did you find this review helpful?
    5 out of 5 stars
    12 July, 2025
    originally posted on http://www.ulta.com
    Image

    Highly recommend

    [I received this product in exchange for my honest review] This product is amazing. Not a strong scent and natural ingredients. Not a gritty or thick texture. Leaves no residue and I love the blue color packaging. Highly recommend
    Did you find this review helpful?
    5 out of 5 stars
    12 July, 2025
    originally posted on http://www.ulta.com
    Image

    Lightweight & Effective

    [I received this product in exchange for my honest review] I've been using this for over a month now and I can say I feel like apart from being a solution afterwards it also supports in deterring breakouts. I've had very minimal break outs since using this, the formula is very smooth and it's lightweight so I can be layered with other skincare products.
    Blackbeautyfifi
    Did you find this review helpful?
    5 out of 5 stars
    11 July, 2025
    originally posted on http://www.ulta.com
    Image

    Love it

    [I received this product in exchange for my honest review] I've been using the this for a few weeks and really like how lightweight and non-drying it is. It absorbs quickly, feels calming on my skin, and hasn't caused irritation like some harsher acne products. My breakouts look less inflamed, and my skin feels more balanced overall. It's pricey but worth it for how gentle yet effective it is. I love that it supports the skin barrier too, not just fights acne.
    Mar
    Did you find this review helpful?

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