Differin Retinoid Adapalene Gel 0.1% Acne Treatment for Face and Body - 45g: Unscented, 1-Pack
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Guests are saying
This product has received mixed reviews for its effectiveness in treating acne. Many guests have found it to be a game-changer for their skin, significantly reducing acne and improving skin texture. However, some guests with sensitive skin experienced irritation and chemical burns. Consistency and proper usage are key to achieving the best results.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.5 out of 5 stars with 2361 reviews
effectiveness: 4.37 out of 5
quality: 4.41 out of 5
value: 4.29 out of 5
84% would recommend
626 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
23 March, 2026
good product
works well but takes time
5 out of 5 stars
Thumbs up graphic, would recommend
19 March, 2026
Highly recommend !
It work so good highly recommend! Every time I see little bumps coming out or pimples I put it on and it takes them off
5 out of 5 stars
18 March, 2026
originally posted on influenster.com

Great stuff!
As a Master Esthetician, this is one of the best acne products. It’s many dermatologists favorite as well. It is so nice to get it over the counter now! It’s gentle enough to work for most skin types and is such a great resource for stubborn acne, without breaking the bank!
5 out of 5 stars
Thumbs up graphic, would recommend
15 March, 2026Verified purchase
Greatest yet.
This product helped me get rid of an ingrown acne bump on the back of my neck. It slowly started disappearing after using it for about three weeks. You don’t have to be too generous with it, but the affected area does need a good layer applied. It goes a long way. I’ve used very little, and see results already. It tames my acne and keeps it inactive for the most part. Don’t use it in the sun. Some minor irritation may occur, stop use for some days up to a week then reuse. Give this a chance. It works.
5 out of 5 stars
28 February, 2026
originally posted on differin.com
Shockingly Effective for Melasma
I've had a quarter-sized spot on my cheek for decades. I've tried so many different topicals (including prescription) as well as red-light therapy, and nothing has worked. I didn't want laser treatments, so I resigned myself to living with melasma. Two weeks ago, I saw Differin Gel being advertised for dark spots and thought I'd give it a try. After the first application, I thought I noticed a subtle lightening that continued over the next two days. By day 3, I knew it was definitely not my imagination. Now a week-and-a-half in, the spot is about 75% lighter, and I'm shocked! I may be rid of it after all!
4 out of 5 stars
27 February, 2026
originally posted on influenster.com

Great product!
I like differin! I mostly use it as a spot treatment. It works well but it does cause my skin to dry out if I use it repeatedly. The tube is convenient and it doesn’t have a scent.
5 out of 5 stars
25 February, 2026
originally posted on influenster.com

Dries out blemishes and renews the skin!
loveeee differn gel! Whenever I have a new pimple or blemishes I moisturize and then apply just a small amount, usually putting the tip and dispensing from that, over the area and re apply moisturizer! It has really helped get rid of my acne and it’s super helpful! It will dry you out and might make your makeup look weird but Just keep moisturizing! I’d also advise to not pick at the dryed skin or area because it will make your skin worse and red!! It has no scent and I’d be careful if you have sensitive skin because this can be heavy duty depending on how much you put on !! 🤍
5 out of 5 stars
Thumbs up graphic, would recommend
22 February, 2026Verified purchase
(no review title)
Love this product gets the job done
5 out of 5 stars
20 February, 2026
originally posted on influenster.com

Quick-absorbing, clears acne
I’ve been using it and the gel absorbs quickly without feeling greasy. After a while, my skin showed a noticeable reduction in breakouts and felt much smoother , so it’s definitely worth trying if you’re in a treatment phase.
4 out of 5 stars
20 February, 2026
originally posted on influenster.com

Effective yet gentle skincare
I’m 41 and have been using this off and on since i was a kid. I love that it is mild enough to not cause TOO much redness or irritation but still strong enough to be effective. When I use it regularly, I definitely notice a reduction in my hormonal acne and better clarity overall. I did take a star off because I wish it was just a little bit more powerful and yet I do also have a period of adjustment any time I stop using it for a period and have to start up again.
5 out of 5 stars
9 February, 2026
originally posted on influenster.com

Great for acne.
This treatment helped me so much with my acne, it doesn’t cause irritation or redness and it’s great for sensitive skin. The texture is not too thick and it’s lightweight.
1 out of 5 stars
Thumbs down graphic, would not recommend
6 February, 2026Verified purchase
(no review title)
No didn’t work
5 out of 5 stars
Thumbs up graphic, would recommend
5 February, 2026Verified purchase
(no review title)
excellent
5 out of 5 stars
1 February, 2026
originally posted on influenster.com

Perfect for hormonal acne
This product was my go to for my hormonal acne it worked amazing for my breakouts. Did not cause any Irritation on my skin. The frequency was about 1-2 times a month and was always empty for disposal.
5 out of 5 stars
30 January, 2026
originally posted on influenster.com

Acne treatment must have
I use Differin Gel for hormonal acne, and I noticed the redness of my acne was relieved after just one night. My skin feels calmer and less inflamed. I highly recommend using it at night only and, most importantly, being consistent. With regular use, you can really see a difference over time.
5 out of 5 stars
29 January, 2026
originally posted on influenster.com

THE BEST
That’s how good it is!!! It’s almost empty lol!! The most effective product. I put it on the pimple overnight and it workss but you need to put it multiple days.
5 out of 5 stars
28 January, 2026Verified purchase
(no review title)
Not too strong but has helped clear my acne
4 out of 5 stars
27 January, 2026
originally posted on influenster.com

Eliminates Stubborn Acne
This treatment is perfect for targeting stubborn breakouts. It’s a spot treatment so it is drying, a little goes a long way. Use with moisturizer.
3 out of 5 stars
26 January, 2026
originally posted on differin.com
Finally a nice cream that really helps
I like Differin because being a little older (74)it’s helping smooth my face!
5 out of 5 stars
22 January, 2026
originally posted on influenster.com

Strong on acne
This is a stronger acne treatment gel that I’ve used during a bad breakout. It definitely works faster than most and it’s strong. It’s important to moisturize right after as I did notice my skin was dried. I didn’t get any irritation and th container is easy to use.