Systane Hydration Multi-Dose Preservative Free Dry Eye Drops - 0.34 fl oz
$16.89 ($49.68/fluid ounce)See 1 deal for this item
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$5 Target GiftCard with 2 select allergy relief tablets
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Related Categories
4.5 out of 5 stars with 243 reviews
quality: 3.77 out of 5
value: 3.27 out of 5
56% would recommend
25 recommendations
2 out of 5 stars
Thumbs down graphic, would not recommend
19 April, 2026
Too thick, Not hydrating, make my eyes itch, and cause a weird film
I find these specific Systane drops too thick, they don't stay in the eye, don't provide any hydration for me. I was also disappointed that it is to be used within 90 days. No mention of it on in the details on the website but the box only. I need it only a few times a month, so the bottle will go to waste. I will go back to the vials, more useful, economical and long lasting.
5 out of 5 stars
11 January, 2026Verified purchase
(no review title)
Great for my dry eyes due to my allergies
1 out of 5 stars
Thumbs down graphic, would not recommend
12 November, 2025Verified purchase
(no review title)
This bottle is a horrible design. Somehow it leaks but then when you go to put drops in your eye, it'll either bubble or drop a massive messy drop.
5 out of 5 stars
Thumbs up graphic, would recommend
10 October, 2025Verified purchase
Systane Hydration Preservative Free Eye Drops.
I've been purchasing these eye drops for a while and daily use has greatly improved my dry eye condition.
5 out of 5 stars
Thumbs up graphic, would recommend
9 July, 2025Verified purchase
Very good product. I highly recommend it!
Quality product. works great to relieve dry eyes.
2 out of 5 stars
Thumbs down graphic, would not recommend
20 March, 2025
Bottle Sucks
We can't stand the new bottle and want a different brand with a normal dropper. What to pick?? We have used Systane forever but cant stand the new bottle.
3 out of 5 stars
Thumbs down graphic, would not recommend
26 May, 2024Verified purchase
Not much help
I have had very dry eyes from allergies and this was recommended to help. Been using them for almost a month with no significant improvement. I put drops in and feel like i need it again less than an hour later.
4 out of 5 stars
Thumbs up graphic, would recommend
20 March, 2024Verified purchase
Bottle sucks drops are great
I got ICL surgery and this was a doctor recommend for healing and dry eyes. The bottle isn’t great air gets trapped after one use and it’s annoying but the drops are good. Wish the bottle was better for how spendy they are I have noticed it helps with red eyes from dryness too!
5 out of 5 stars
Thumbs up graphic, would recommend
26 December, 2023Verified purchase
Helps Dry Eyes
Systane hydration is a great product. Really helps dry eyes. I like that the extra moisture this product provides. I also like that it is a #1 doctor recommended brand. Also, it's preservative free!
3 out of 5 stars
Thumbs down graphic, would not recommend
2 November, 2023Verified purchase
I prefer the vials
I found the bottle difficult to work with. Air left the bottle permanently after one squish and I felt like I had to touch it to my eye to make sure the drops would land in the correct spot.
1 out of 5 stars
15 October, 2023
Not helping but worse !
I usually use Refresh brand and got this from the eye doctor office as sample to try. First time I tried it, I woke up with swollen, itchy red eyes. I thought it was something else. I used a second time and it gave me the same problem. I went to eye doctor to treat my swollen eyes and she told me to stop using it which I did of course. I went back to Refresh brand since then.
3 out of 5 stars
8 July, 2023
originally posted on https://www.myalcon.com/consumer/

Dry eyes
This product is okay. I think it would be better if it was also for red itching eyes
5 out of 5 stars
7 July, 2023
originally posted on https://www.myalcon.com/consumer/

Refreshing
These eye drops are great. They felt very refreshing and took any redness or itchiness out of my eyes. I would definitely recommend please eye drops
4 out of 5 stars
7 July, 2023
originally posted on https://www.myalcon.com/consumer/

Does the job
The product is good but I find myself needing to apply more frequently than other brands purchased in the past.
4 out of 5 stars
7 July, 2023
originally posted on https://www.myalcon.com/consumer/

Feels good in my eyes
This product does feel like it soothes and hydrated my eyes! My eyes have a tendency to feel dry and red, and these drops bring a sense of cooling to my eyes. I'm not sure about how they dispense because it's hard to be accurate with them, so that's the only negative I can say about it.
5 out of 5 stars
6 July, 2023
originally posted on https://www.myalcon.com/consumer/

Works great
This years allergies have been really hard on my eyes. These drops have definitely helped my dry eyes.
5 out of 5 stars
4 July, 2023
originally posted on https://www.myalcon.com/consumer/

HYDRATION Preservative-Free Dry Eye Drop
HYDRATION Preservative-Free Dry Eye Drop effectively relieves dry eyes
5 out of 5 stars
4 July, 2023
originally posted on https://www.myalcon.com/consumer/

Hydrating!
These systane hydration eye drops are where its at! I had pink eye about 2 weeks ago and have suffered from severe dry eye since, I was waking up and my eyes were literally stuck shut, these drops have saved my eyes! I put drops in before bed and I wake up with just regular dry eyes now!
5 out of 5 stars
3 July, 2023
originally posted on https://www.myalcon.com/consumer/

Review for sustained drops
These eye drops work great. My eyes are sensitive to most eye drops I've tried, which often burn and still leave my eyes feeling dry. Systane eye drop actually leave my eyes feeling lubricated without the burn. I will definitely use these from now on.
5 out of 5 stars
2 July, 2023
originally posted on https://www.myalcon.com/consumer/

Very impressed!!
Out of all of the eye wetting drops I have tried, this one did the trick! I only had to put one drop in both eyes, and they stayed moist for hours! These weren't red eye relief, which would have been the cherry on top, but they definitely did what they were intended to do. So keep in mind, if you're looking for something to get rid of red eyes, this wouldn't be for you, but for all other purposes, I approve! I had something stuck in my eye that, for the life of me, I just couldn't find or remove. I flushed my eye with this and voila! It was instantly relieved. Will definitely purchase in the near future!