New ArrivalsEasterClothing, Shoes & AccessoriesHomeKitchen & DiningOutdoor Living & GardenFurnitureGroceryHousehold EssentialsBabyBeautyPersonal CareHealthWellnessBackpacks & LuggageSports & OutdoorsToysElectronicsVideo GamesMovies, Music & BooksSchool & Office SuppliesParty SuppliesGift IdeasGift CardsPetsUlta Beauty at TargetShop by CommunityTarget OpticalDealsClearanceTarget New ArrivalsHome Decor Ideas & TrendsTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Target Circle™Target Circle™ CardTarget Circle 360™Registry & Wish ListWeekly AdFind Stores
Cortizone-10 Intensive Healing Hydrocortisone Anti-Itch Cream - 2 of 4Cortizone-10 Intensive Healing Hydrocortisone Anti-Itch Cream - 3 of 4Cortizone-10 Intensive Healing Hydrocortisone Anti-Itch Cream - 4 of 4
Cortizone-10 Intensive Healing Hydrocortisone Anti-Itch Cream - 1 of 4

Cortizone-10 Intensive Healing Hydrocortisone Itch Relief Cream - 1oz

$5.49
Count1oz

In Stock

Eligible for registries and wish lists

Save 5% every day

With Target Circle™ Card

At a glance

About this item

Highlights

  • INCLUDES: One (1) 1 oz. tube of Cortizone-10 Maximum Strength* Intensive Healing Itch Relief Cream (*Among topical anti-itch OTCs)
  • RELIEVES ITCH: Cortizone-10 helps relieve itch associated with minor skin irritations, inflammation, and rashes due to eczema, psoriasis, insect bites, seborrheic dermatitis, poison ivy, oak, sumac, and more
  • MOISTURIZES & RESTORES: Includes 10 moisturizers, plus vitamins A, C, and E to nourish skin and help restore skin's moisture barrier
  • ACTIVE INGREDIENT: Formulated with 1% hydrocortisone for maximum-strength itch relief without a prescription
  • TRAVEL ESSENTIALS: The perfect addition to first aid kits, camping essentials and travel bags for anytime you need on-the-go relief
  • FAST ACTING: Relieves itch in five minutes with 24-hour moisture that's gentle on skin, fragrance free, and dye free
  • DOCTOR RECOMMENDED: Cortizone-10 is the No. 1 doctor-recommended OTC anti-itch brand* and is suitable for adults and children ages 2+ (*2024 IQVIA Study)

Description

Stop the itchsanity with Cortizone-10 Maximum Strength* Intensive Healing Itch Relief Cream. Formulated with 1% hydrocortisone, this anti-itch cream starts working fast to relieve itch associated with minor skin irritations, inflammation, and rashes due to eczema, psoriasis, insect bites, seborrheic dermatitis, poison ivy, oak, sumac, detergents, jewelry, cosmetics and soap. Cortizone-10 Intensive Healing Itch Relief Cream uses 10 moisturizers and vitamins A, C, and E to nourish and hydrate skin in a fragrance-free and dye-free formula. It's the perfect addition to first aid kits, camping gear and travel essentials, so itching from pesky mosquito bites doesn't ruin your time outdoors. No wonder it's the No. 1 doctor-recommended OTC anti-itch brand**.
*Among Topical Anti-Itch OTCs
**2024 IQVIA Study
Trial/Mini/Travel Size: Yes
Health Facts: Dye-Free
Treats and/or Prevents Against: Fire Ants, Mosquitoes
Product Form: Cream
Active Ingredient(s): Hydrocortisone 1%
Net weight: 1 Ounces
TCIN: 11146925
UPC: 041167003503
Item Number (DPCI): 245-07-0537
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

hydrocortisone(1%).

Purpose

Anti-Itch..

Uses

eczema, psoriasis, poison ivy, oak, sumac, insect bites, detergents, jewelry, cosmetics, soaps, seborrheic dermatitis.

When using this product

When using this product: avoid contact with eyes,do not use more than directed unless told to do so by a doctor,do not put directly into the rectum by using fingers or any mechanical device or applicator.

Stop use and ask a doctor if

Stop use and ask a doctor if: condition worsens, symptoms persist for more than 7 days or clear up and occur again within a few days, and do not begin use of any other hydrocortisone product unless you have asked a doctor,rectal bleeding occurs.

For Itching of Skin Irritation, Inflammation, and Rashes: Adults and Children 2 Years of Age and Older

Apply to affected area not more than 3 to 4 times daily.

For Itching of Skin Irritation, Inflammation, and Rashes: Children Under 2 Years of Age

Ask a doctor.

For External Anal and Genital Itching, Adults

When practical, clean the affected area with mild soap and warm water and rinse thoroughly. Gently dry by patting or blotting with toilet tissue or a soft cloth before applying. Apply to affected area not more than 3 to 4 times daily.

For External Anal and Genital Itching: Children Under 12 Years of Age

Ask a doctor.

Inactive ingredients

water, glycerine, dimethicone, petrolatum, jojoba esters, cetyl alcohol, aloe barbadensis leaf juice, stearyl alcohol, distearyldimonium chloride, cetearyl alcohol, steareth-21, steareth-2, polysorbate 60, stearamidopropyl pg-dimonium chloride phosphate, methyl gluceth-20, propylene glycol, chamomilla recutita (matricaria) flower extract, tocopheryl acetate, magnesium ascorbyl phosphate, hydrolyzed collagen, hydrolyzed elastin, retinyl palmitate, hydrolyzed jojoba esters, glyceryl stearate, edta, ppg-12/smdi copolymer, potassium hydroxide, beta glucan, menthyl lactate, diazolidinyl urea, benzyl alcohol, methylparaben, bht, propylparaben (283-124)

Shipping details

Estimated ship dimensions: 5.3 inches length x 2.7 inches width x 1.1 inches height
Estimated ship weight: 0.1 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: Has anyone felt burning from this product?

submitted by Upset mom - 1 year ago

  • A: Thank you for your inquiry. Cortizone-10 Intensive Healing Anti-Itch Crème is safe if used as described on the drug facts label. It is recommended to stop this product if burning continues and consult with your healthcare professional.

    submitted byCortizone 10 - 1 year ago
    Brand expert

Q: After I apply cortizone-10 cream on my face in the night, can I use band-aid to cover it to sleep?

submitted by Steven K - 4 years ago

  • A: When I use it on my face, it generally soaks in pretty well and isn’t very greasy. But I suppose if you want to really lay it on, you could use a patch bandaid. And to others, it ok helps the inflammation on pimples, not the actual blackheads or whiteheads.

    submitted byJamesdusoleil - 1 year ago

  • A: Hi I’m just wondering why you put it on your face ? I’m interested in if it helps pimples

    submitted byPamela - 4 years ago

Q: Could this be used on my scalp??

submitted by Er - 7 months ago

  • A: Thank you for your inquiry. Please use Cortizone-10 Intensive Healing Eczema Relief Lotion as described on the drug facts label. It is intended for external use only. It comes in lotion form and can be used on the scalp to temporarily relieve the itching and discomfort associated with minor skin irritations, rashes, and inflammation due to eczema. When using this product, avoid contact with eyes. Please consult with your healthcare professional for further guidance on how to use Cortizone-10 Intensive Healing Eczema Relief Lotion for your specific needs.

    submitted byCortizone 10 - 5 months ago
    Brand expert

Q: Could this be used on children under 2 years old?

submitted by Norma - 10 months ago

  • A: Thank you for your inquiry. It is recommended to use the Cortizone 10 Intensive Healing Anti-Itch Crème as described on the drug facts label. Please consult with your healthcare professional before using on children under 2 years of age.

    submitted byCortizone 10 - 9 months ago
    Brand expert

Q: Is this product supposed to come with a seal?

submitted by Brenda - 2 years ago

  • A: Our Cortizone-10 products do not come with tamper-evident seals. Rest assured, they are safe to use as packaged. If you have any other questions or concerns, feel free to reach out. We're always here to help you get fast, effective itch relief! #StoptheItchsanity

    submitted byCortizone 10 - 2 years ago
    Brand expert

Q: Does this help with insect bites?

submitted by Tee - 2 years ago

  • A: Yes, Cortizone-10 is highly effective for relieving the itch and irritation from insect bites! Its 1% hydrocortisone formula helps stop the itch fast and provides lasting relief, so you can get back to enjoying life without the annoying itch. #StoptheItchsanity #BugBiteRelief

    submitted byCortizone 10 - 2 years ago
    Brand expert

Q: Looking at the ingredients list it's unclear whether this product contains palm oil derivatives. Are ingredients derived from palm oil used to make this product, and, if so, is it sustainably sourced?

submitted by Bebe - 6 years ago

  • A: Cortizone 10 Intensive Healing Anti-Itch Creme does contain ingredients sourced from palm oil. Due to the numerous suppliers of raw material Sanofi cannot guarantee the palm oil in Cortizone 10 Intensive Healing Anti-Itch Creme is sustainable.

    submitted bySanofi - 6 years ago
See all questions (7)

Additional product information and recommendations

Discover more options

Frequently bought together

Guests also viewed

4.7 out of 5 stars with 1462 reviews
quality: 4.59 out of 5
value: 4.52 out of 5
88% would recommend
96 recommendations
4 out of 5 stars
26 March, 2026
originally posted on influenster.com
Image

Helps my child

My son has struggled with eczema since birth. This product has made his skin feel better and is pretty thing but does the trick. We apply it when he is having an issue and the flare up goes away quickly.
ElizabethH
Did you find this review helpful?
5 out of 5 stars
19 March, 2026
originally posted on influenster.com
Image

It definitely helps

Cortizone 10 has been a lifetime saver for my eczema. I used to deal with nonstop itching and painful flareups but after using the lotion, my skin has finally started to heal up.
OlgaM
Did you find this review helpful?
5 out of 5 stars
13 March, 2026
originally posted on influenster.com
Image

Great for itching and/or sensitive dry skin

A actual go to product! I have tested multiple anti-itching creams and this is one of the few that I keep coming back to. You get a great amount for the price and everything holds well. I use this almost daily and like it states, it helps with more than just itching. Even at my work place, I have been somewhat sensitive to some of the chemicals that are being used but after applying this, I feel much more blessed that this product exists.
JeffreyT
Did you find this review helpful?
5 out of 5 stars
27 February, 2026
originally posted on influenster.com
Image

Skin cream

I love this product . I love use it whenever I have ent skin irritation it’s very practical and effective it has a good texture and your skin absorbs it well good packaging , it’s soft
RachelA
Did you find this review helpful?
5 out of 5 stars
25 February, 2026
originally posted on influenster.com
Image

I love it for my skin

Is absorbs easy and helps with irritation and doesn't feel dry or caked. I've used it multiples consistently with no issues, no residue either.
SayvonW
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
25 February, 2026Verified purchase

(no review title)

Works fast and no sticky residue.
April
quality: 5 out of 5
value: 4 out of 5
Did you find this review helpful?
5 out of 5 stars
23 February, 2026
originally posted on influenster.com
Image

Good product!

This is a good product. The cream goes on smoothly, absorbs quickly and stops the itching right away. It also lasts a long time, plus leaves the skin feeling soft.
GayleF
1 guest found this review helpful. Did you?
5 out of 5 stars
20 February, 2026
originally posted on Cortizone 10

(no review title)

I've been using this for about the last 4 months. We buy it quite often and use it a few times a day or whenever the eczema flares up. It really does work quickly and takes the itch away within a minute or two.
Josephine
Did you find this review helpful?
1 out of 5 stars
Thumbs down graphic, would not recommend
13 February, 2026Verified purchase

Arrived open without non-tampering seal

I've been experiencing opened/used/tampered products in the past few months whenever I order online (or even in-store). This is also why I’m honestly using Target less and less. This time, the product arrived outside of its box, a bit squeezed, and without the seal that new products (specially those medically related) have. At this point, not even the discounts or coupons they offer make buying there worth it.
Vic
1 guest found this review helpful. Did you?
5 out of 5 stars
11 February, 2026
originally posted on influenster.com
Image

Works well

This helps me with the rash I get on my chest, and it works wonderfully. In just a few hours, it's gone. I love it so much, and it makes my skin so soft.
dayannarab_9578
1 guest found this review helpful. Did you?
5 out of 5 stars
8 February, 2026
originally posted on influenster.com
Image

ideal

Highly effective in controlling skin redness and irritation with a pleasant smell I recommend it 100%. At home, all members of the family use it. .........
Yudeisy M
Did you find this review helpful?
5 out of 5 stars
7 February, 2026
originally posted on influenster.com
Image

Soothing cream, works fast

This cream really helped calm my eczema irritation. It absorbs well, doesn’t sting, and keeps my skin hydrated for hours. Definitely something I keep at home when my skin flares up.
Rosabel F
1 guest found this review helpful. Did you?
1 out of 5 stars
6 February, 2026Verified purchase

Opened and damaged item

This is as a gift. The box came with no insert and upon opening the tube was already punctured and opened. It’s obviously a used cream which was probably returned by another customer. Target do better with your quality control.
Flgrandma
quality: 1 out of 5
value: 1 out of 5
Did you find this review helpful?
5 out of 5 stars
6 February, 2026
originally posted on influenster.com
Image

Stops even the most gnarliest of itches

I was doing some yard work not too long ago and to my dismay I ended up with poison ivy!! The itch was unbelievable and this lil tube of goodness was the only thing that could give me relief enough so that I didn't scratch the unbearable itch!! Thank you Cortizone 10...you're a life saver
Audrey L
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
5 February, 2026Verified purchase

(no review title)

Excellent, thank you.
Trinity
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
30 January, 2026Verified purchase

(no review title)

Must-have for eczema parents! This cream has been a lifesaver for my son’s flare-ups. It clears up dry, red patches faster than anything else we’ve used. It’s gentle (burns a bit but mixed with aquaphor) and effective!
Nicky
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
29 January, 2026
originally posted on influenster.com
Image

Eczema Relief!

This cream is a life saver !!! My 6 year old suffers from dry skin and itchy and redness due to eczema! I apply this cream every morning and night ! And the eczema is almost fully cleared overnight! The package is also amazing well packed !
tutoxica_9182
Did you find this review helpful?
5 out of 5 stars
28 January, 2026
originally posted on influenster.com
Image

Provides fast relief from itching and redness whil

Works great for eczema and itching. It provides fast relief, reduces redness, and keeps my skin feeling calm and moisturized. Lightweight, non greasy, and very effective. Highly recommended.
melanyb50_7236
Did you find this review helpful?
5 out of 5 stars
27 January, 2026
originally posted on influenster.com
Image

Relieves Winter Eczema!

Proof in my picture that I use this every day - it’s all gone and I need more! I’ve always struggled with Eczema on my hands and this starts working as soon as I use it. It’s my favorite go-to hand lotion! Highly Recommend!
dominiquem164_8690
1 guest found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
18 January, 2026

Product Tampered With

Box seemed to be be opened. No seal. It appears to be tampered with.
Ms D
Did you find this review helpful?

Get top deals, latest trends, and more.

Privacy policy

Footer

About Us

About TargetCareersNews & BlogTarget BrandsBullseye ShopSustainability & GovernancePress CenterAdvertise with UsInvestorsAffiliates & PartnersSuppliersTargetPlus

Help

Target HelpReturnsTrack OrdersRecallsContact UsFeedbackAccessibilitySecurity & FraudTeam Member ServicesLegal & Privacy

Stores

Find a StoreClinicPharmacyTarget OpticalMore In-Store Services

Services

Target Circle™Target Circle™ CardTarget Circle 360™Target AppRegistrySame Day DeliveryOrder PickupDrive UpFree 2-Day ShippingShipping & DeliveryMore Services
PinterestFacebookInstagramXYoutubeTiktokTermsCA Supply ChainPrivacy PolicyCA Privacy RightsYour Privacy ChoicesInterest Based AdsHealth Privacy Policy