Cortizone-10 Intensive Healing Hydrocortisone Itch Relief Cream - 1oz
Highly rated
$5.49
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4.7 out of 5 stars with 1462 reviews
quality: 4.59 out of 5
value: 4.52 out of 5
88% would recommend
96 recommendations
5 out of 5 stars
13 March, 2026
originally posted on influenster.com

Great for itching and/or sensitive dry skin
A actual go to product! I have tested multiple anti-itching creams and this is one of the few that I keep coming back to. You get a great amount for the price and everything holds well. I use this almost daily and like it states, it helps with more than just itching. Even at my work place, I have been somewhat sensitive to some of the chemicals that are being used but after applying this, I feel much more blessed that this product exists.
5 out of 5 stars
Thumbs up graphic, would recommend
25 February, 2026Verified purchase
(no review title)
Works fast and no sticky residue.
5 out of 5 stars
23 February, 2026
originally posted on influenster.com

Good product!
This is a good product. The cream goes on smoothly, absorbs quickly and stops the itching right away. It also lasts a long time, plus leaves the skin feeling soft.
1 out of 5 stars
Thumbs down graphic, would not recommend
13 February, 2026Verified purchase
Arrived open without non-tampering seal
I've been experiencing opened/used/tampered products in the past few months whenever I order online (or even in-store). This is also why I’m honestly using Target less and less. This time, the product arrived outside of its box, a bit squeezed, and without the seal that new products (specially those medically related) have. At this point, not even the discounts or coupons they offer make buying there worth it.
5 out of 5 stars
11 February, 2026
originally posted on influenster.com

Works well
This helps me with the rash I get on my chest, and it works wonderfully. In just a few hours, it's gone. I love it so much, and it makes my skin so soft.
1 out of 5 stars
6 February, 2026Verified purchase
Opened and damaged item
This is as a gift. The box came with no insert and upon opening the tube was already punctured and opened. It’s obviously a used cream which was probably returned by another customer. Target do better with your quality control.
5 out of 5 stars
6 February, 2026
originally posted on influenster.com

Stops even the most gnarliest of itches
I was doing some yard work not too long ago and to my dismay I ended up with poison ivy!! The itch was unbelievable and this lil tube of goodness was the only thing that could give me relief enough so that I didn't scratch the unbearable itch!! Thank you Cortizone 10...you're a life saver
5 out of 5 stars
Thumbs up graphic, would recommend
5 February, 2026Verified purchase
(no review title)
Excellent, thank you.
5 out of 5 stars
Thumbs up graphic, would recommend
30 January, 2026Verified purchase
(no review title)
Must-have for eczema parents! This cream has been a lifesaver for my son’s flare-ups. It clears up dry, red patches faster than anything else we’ve used. It’s gentle (burns a bit but mixed with aquaphor) and effective!
1 out of 5 stars
Thumbs down graphic, would not recommend
18 January, 2026
Product Tampered With
Box seemed to be be opened. No seal. It appears to be tampered with.
4 out of 5 stars
18 January, 2026
originally posted on influenster.com

Fast acting!
Fast acting cortisone 10 intensive healing formula gives fast relief with a gentle scent. The texture is great, along with the easy open packaging.
5 out of 5 stars
Thumbs up graphic, would recommend
17 January, 2026Verified purchase
Rave to Joel
I made a curbside pick up for this order and the gentleman Joel was very attentive and had exceptional customer service. In El Centro CA Also used this product before and it’s a 10 for my eczema
1 out of 5 stars
Thumbs down graphic, would not recommend
17 January, 2026Verified purchase
(no review title)
The box was opened, and the product doesn't have a seal at all!
5 out of 5 stars
8 January, 2026
originally posted on influenster.com

Helped my eczema!
[This review was collected as part of a promotion.] I used this to help with an eczema breakout I was having and I loved it! It reallllly helped with the constant itchiness I was having and helped soothes the redness and rashness that my skin was experiencing as well. It sunk into the skin pretty easily so I wasn’t getting the cream all over my clothes or anything like that unlike other products I have used. I will definitely be repurchasing.
5 out of 5 stars
7 January, 2026Verified purchase
Helpful
Very helpful for itching. I baby girl sometimes feels very itchy. It should be in the house.
5 out of 5 stars
Thumbs up graphic, would recommend
30 December, 2025Verified purchase
(no review title)
Works well for dermatitis and eczema.
3 out of 5 stars
11 December, 2025
(no review title)
The box was opened and the actual tube’s seal also was opened. Cream was slightly at the top of the opening. Not sure if it was used but it was opened! Not cool, Target!
5 out of 5 stars
18 November, 2025
originally posted on influenster.com

Itch relief for eczema
Works great on my sensitive/eczema skin. Helps relieve any itchy areas and absorbs nicely. Usually have to reapply throughout the day, but easy to just toss in my bag and go.
5 out of 5 stars
12 November, 2025
originally posted on influenster.com

Best for Ezcema!
As an adult I just started getting eczema and man when I tell you I be feeling like my skin is about to fall off. It gets so dry and scaly. And once you scratch it doesn’t stop. This cream is so thick that a little goes a long way. You don’t need much. Just put a nice layer on and it’ll work and clear up in a few hours. Best thing for my eczema.!
3 out of 5 stars
4 November, 2025
originally posted on influenster.com

The product works sometimes and does not provide m
The product works sometimes. It all varies on the severity of the rash and the itchiness of the area. The Product has a slightly medicated scent. It goes on as a creamy texture but becomes matte-looking with no hydration.
1 reply from Opella Consumer Care team - 5 months ago
Thank you for sharing your feedback. We’re sorry to hear about your experience and would love the opportunity to assist you. Please reach out to us at 866-844-2798, option 1, or visit this link to contact us: https://www.sanofimedicalinformation.com/s/submit-a-question?language=en_US&HCP=No&CN=US.