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Excedrin Extra Strength Pain Reliever Caplets - Acetaminophen/Aspirin (NSAID) - 2 of 4Excedrin Extra Strength Pain Reliever Caplets - Acetaminophen/Aspirin (NSAID) - 3 of 4Excedrin Extra Strength Pain Reliever Caplets - Acetaminophen/Aspirin (NSAID) - 4 of 4
Excedrin Extra Strength Pain Reliever Caplets - Acetaminophen/Aspirin (NSAID) - 1 of 4

Excedrin Extra Strength Pain Reliever Caplets - Acetaminophen/Aspirin (NSAID) - 100ct: Whole Body Headache and Migraine Treatment

$12.99 ($0.13/count)See 1 deal for this item
Size100ct

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At a glance

About this item

Highlights

  • One bottle of 100 Excedrin Extra Strength Caplets
  • Relieves pain from headache, colds, menstrual cramps, toothaches, muscular aches and arthritis
  • Excedrin Extra Strength works in 3 ways to relieve headaches
  • Excedrin Extra Strength caplets contain two pain relievers and a booster for enhanced effect
  • Headache relief pain reliever available in convenient caplet form
  • HSA and FSA eligible item. Medicare Advantage OTC (MAOTC) eligible. *OTC benefits and eligible products vary by plan. Check your plan for specific details.

Description

Excedrin Extra Strength Caplets provide clinically proven headache relief fast. Excedrin works in 3 ways to relieve headaches: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance the pain relief effect. Available in convenient caplet form, this nonprescription pain relief medicine works as hard as you do, combining aspirin and acetaminophen with caffeine. These active ingredients create a powerful formula with two pain relievers and a booster to offer temporary relief of pain from headaches, colds, premenstrual and menstrual cramps, arthritis, tooth pain and muscle pain. For some, headache pain relief with this Excedrin extra strength pain reliever can start in 15 minutes. Get headache relief fast with Excedrin, the headache expert.
Suggested Age: 12 Years and Up
Health Facts: Contains Acetaminophen
Active Ingredient Strength Value: 250 Milligrams
Product Warning: Contains Acetaminophen
Product Form: Caplet
Primary Active Ingredient: Acetaminophen
Package Quantity: 100
Net weight: 3.46 Ounces
TCIN: 11003626
UPC: 300672000910
Item Number (DPCI): 094-01-0571
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

acetaminophen(250mg), aspirin (nsaid*)(250mg), caffeine(65mg).

Purpose

Pain Reliever, Pain Reliever, Pain Reliever Aid..

Uses

headache, a cold, arthritis, muscular aches, toothache, premenstrual & menstrual cramps.

Allergy alert: Aspirin may cause a severe allergic reaction which may include:

Allergy alert: Aspirin may cause a severe allergic reaction which may include:: hives, facial swelling ,asthma (wheezing) ,shock.

Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 8 caplets in 24 hours, which is the maximum daily amount, with other drugs containing acetaminophen,3 or more alcoholic drinks every day while using this product.

Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you

Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you: are age 60 or older ,have had stomach ulcers or bleeding problems,take a blood thinning (anticoagulant) or steroid drug,take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) ,have 3 or more alcoholic drinks every day while using this product,take more or for a longer time than directed.

Do not use

Do not use: if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer,with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.

Ask a doctor before use if

Ask a doctor before use if: you have liver disease,stomach bleeding warning applies to you,you have a history of stomach problems, such as heartburn,you have high blood pressure, heart disease, liver cirrhosis, or kidney disease, you are taking a diuretic, you have asthma.

Ask a doctor or pharmacist before use if you are taking

Ask a doctor or pharmacist before use if you are taking: a prescription drug for diabetes, gout, or arthritis ,any other drug, or are under a doctor's care for any serious condition.

Stop use and ask a doctor if

Stop use and ask a doctor if: an allergic reaction occurs. Seek medical help right away,you experience any of the following signs of stomach bleeding: feel faint; vomit blood; have bloody or black stools; have stomach pain that does not get better,ringing in the ears or loss of hearing occurs,painful area is red or swollen,pain gets worse or lasts for more than 10 days,fever gets worse or lasts for more than 3 days,any new symptoms occur. These could be signs of a serious condition.

Directions

Do not use more than directed. Drink a full glass of water with each dose.

Adults and Children 12 Years of Age and Over

Take 2 caplets every 6 hours; not more than 8 caplets in 24 hours

Under 12 Years

Ask a doctor.

Other information

Store at 20 degrees - 25 degrees C (68 degrees - 77 degrees F). Close cap tightly after use. Read all product information before using. Keep this box for important information.

Inactive ingredients

benzoic acid, carnauba wax, fd&c blue #1, hydroxypropylcellulose, hypromellose, light mineral oil, microcrystalline cellulose, polysorbate 20, povidone, propylene glycol, simethicone emulsion, sorbitan monolaurate, stearic acid, titanium dioxide

Question or comments?

1-800-452-0051

Shipping details

Estimated ship dimensions: 2.0626 inches length x 4.25 inches width x 2.0626 inches height
Estimated ship weight: 0.2227 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: How is Excedrin Extra Strength different than Excedrin Migraine?

submitted by BrbK - 3 years ago

  • A: no difference in 'active ingredients' only a few differences in the 'inactive' ingredients

    submitted byksbsgm - 2 years ago

  • A: It's weird that each of their dosing guidelines are so different (considering their active ingredients are exactly the same and their inactive ingredients are almost identical also.)

    submitted byJulie - 1 year ago

  • A: The dosing instructions have to be different in order for them to be able to put migraine on the label. It has the same active ingredients.

    submitted bySarah - 2 years ago

Q: How quickly does this product provide relief from headaches?

submitted by AI Shopping Assistant - 26 days ago

  • A: For some individuals, headache relief can start in just 15 minutes.

    submitted byAI Shopping Assistant - 26 days ago
    Ai generated

Q: What types of pain does this product help alleviate?

submitted by AI Shopping Assistant - 26 days ago

  • A: It helps relieve headache, cold, arthritis aches, muscular pains, toothaches, and menstrual cramps.

    submitted byAI Shopping Assistant - 26 days ago
    Ai generated

Q: What are the active ingredients in this pain reliever?

submitted by AI Shopping Assistant - 26 days ago

  • A: The active ingredients are acetaminophen, aspirin, and caffeine.

    submitted byAI Shopping Assistant - 26 days ago
    Ai generated

Q: What age group is this pain reliever suitable for?

submitted by AI Shopping Assistant - 26 days ago

  • A: This pain reliever is suitable for individuals aged 12 years and older.

    submitted byAI Shopping Assistant - 26 days ago
    Ai generated

Q: What is the maximum dosage for adults and children over 12?

submitted by AI Shopping Assistant - 26 days ago

  • A: Adults and children 12 years and older may take 2 tablets every 6 hours, not exceeding 8 tablets in 24 hours.

    submitted byAI Shopping Assistant - 26 days ago
    Ai generated

Q: is it coated to make it easy to swallow

submitted by Anne - 6 months ago

  • A: Thank you for the question, Anne. Excedrin Extra Strength Caplets are film‑coated, which helps make them smoother and easier to swallow.

    submitted byHaleon - 1 month ago
    Brand expert

Q: Is this product gluten free?

submitted by Susan - 2 years ago

  • A: Hi Susan. Excedrin Extra Strength Caplets do not contain directly added gluten or ingredients derived from wheat, barley, or rye. However, please be aware that we do not test the final product for gluten. Therefore, the presence of trace amounts of gluten resulting from third-party manufacturing processes cannot be ruled out.

    submitted byHaleon - 1 year ago
    Brand expert
See all questions (8)
WARNING:Aspirin may cause a severe allergic reaction which may include; hives, facial swelling, asthma[wheezing],shock For more information, go to https://www.p65warnings.ca.gov/

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Guests are saying

Excedrin Extra Strength is a highly effective pain relief option for headaches, combining acetaminophen, aspirin, and caffeine for fast-acting results. Guests appreciate its easy-to-swallow tablets and convenient packaging, making it a go-to choice for on-the-go relief. Many have reported significant improvements in their headache symptoms, often preferring it over other medications. Its affordability and effectiveness make it a staple in many households, ensuring guests can tackle their pain quickly and efficiently.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.8 out of 5 stars with 6202 reviews
    quality: 4.91 out of 5
    value: 4.79 out of 5
    97% would recommend
    41 recommendations
    5 out of 5 stars
    2 May, 2026Verified purchase

    (no review title)

    It does work for me good. My headache is so bad that working good. I like that pill.
    fakhri
    Did you find this review helpful?
    5 out of 5 stars
    19 March, 2026
    originally posted on influenster.com
    Image

    Works fast with no side effects

    [This review was collected as part of a promotion.] I usually take Tylenol for headaches, but started using Excedrin instead once I received it. The combination of acetaminophen, NSAID, and caffeine is powerful & takes away my headaches almost immediately. The instructions were very easy to follow, and the pill was easy to swallow. I had no side effects from taking this medication. It’s easy to carry in your purse or pocket. I have officially converted & won’t be using Tylenol anymore for my headaches.
    RaeD
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    13 March, 2026
    originally posted on influenster.com
    Image

    Better than ibuprofen

    [This review was collected as part of a promotion.] Using this product I notice the difference, I am used to rely on ibuprofen a lot, but this medicine works better. I know that this medicine has helped with all of my stress headaches caused by work or anxieties if life. I woukd definitely recommend to at least give it a try.
    ADRIANAG
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    18 February, 2026
    originally posted on influenster.com
    Image

    Good pain relief

    [This review was collected as part of a promotion.] Very useful bottle of pain relief! I keep this in my bag for when I have a lot of pain and find it fast acting and very useful. My pain goes away quickly and stays away. This bottle gets rid of any headache, body pain, or aches I have and it always comes in handy!
    AbbyC
    1 guest found this review helpful. Did you?
    4 out of 5 stars
    27 January, 2026
    originally posted on influenster.com
    Image

    Helpful

    I use this product often, couple times a week. It really helps when nothing else will. It takes my horrible headaches away. I would recommend it to anyone who has headaches.
    kaseyc84_1490
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    14 January, 2026
    originally posted on influenster.com
    Image

    Really works!

    [This review was collected as part of a promotion.] I have been taking these for awhile now and it’s been helping me with my headaches. I get very bad headaches, but this really helps them and I’m glad I got them. I highly recommend them.
    jenniferd905_1932
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    9 January, 2026Verified purchase

    Get it

    Love this product. Super fast relief!
    CJB
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    5 January, 2026
    originally posted on influenster.com
    Image

    Great for body pain

    [This review was collected as part of a promotion.] My husband is now a big fan of this product. He has back pain from an old injury. This medication quickly provided relief and he was able to rest and fall asleep easily.
    aphop_3409
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    3 January, 2026

    Top Headache reliever

    Excedrin is a must have in our home.
    Justbecause
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    25 December, 2025
    originally posted on influenster.com
    Image

    Works great

    [This review was collected as part of a promotion.] Top go to for a headache. I love using their for any pain I’m having. Takes care of body aches and headaches within thirty minutes. I’ll always use this product over any other.
    katelynnh28_5318
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    13 December, 2025
    originally posted on influenster.com
    Image

    Highly effective

    I recommend this for everyone. Highly effective and show effective within 10 to 15 minutes. This is the only medicine that works for me every single time. Capsule shaped so are easier to swallow.
    prathap2_1826
    2 guests found this review helpful. Did you?
    4 out of 5 stars
    12 November, 2025
    originally posted on influenster.com
    Image

    Great for on the go

    [This review was collected as part of a promotion.] Great for headaches, easy to swallow meanwhile very effective when the pain is unbearable. No taste at all so thats great, nice kid proof bottle. Sold everywhere.
    aprila83_6321
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    9 November, 2025
    originally posted on influenster.com
    Image

    Only option

    Excedrin is the only product that will get rid of a headache for me. I’ve tried so many other options and they always take me back to Excedrin. It kicks in quickly. I buy the bottles with higher caplets counts as then you get the better price per caplet. The packaging is fine.l, not too hard to get open. If you have not tried excedrin yet for a headache, you should.
    lindal370_5345
    1 guest found this review helpful. Did you?
    4 out of 5 stars
    6 November, 2025
    originally posted on influenster.com
    Image

    Great product

    [This review was collected as part of a promotion.] I got to used it when I’m out of the Tylenol and ibuprofen at home. It worked really great in a minutes, my headache got over and make me easy to sleep. It’s not expensive to get.
    kimp268_8789
    1 guest found this review helpful. Did you?
    4 out of 5 stars
    4 November, 2025
    originally posted on influenster.com
    Image

    worked within 15 mins for me

    [This review was collected as part of a promotion.] it worked within 15 mins. feel like more effective than standard pain relievers. good value. nice packaging. recommend using it occasionally rather than daily
    bobaqueen_604
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    14 October, 2025
    originally posted on influenster.com
    Image

    Pain reliever

    [This review was collected as part of a promotion.] I like excedrin extra strength headache. I used it whenever my head is hurt. The packaging is full of information that we need. Easy to read. And this is not gel
    Did you find this review helpful?
    5 out of 5 stars
    7 October, 2025
    originally posted on influenster.com
    Image

    Helped with my chronic headaches

    [This review was collected as part of a promotion.] I get chronic headaches and these painkillers were really great, good for an extra boost when a low dose doesn't cut it. I will be buying this again
    emmag175_7146
    Did you find this review helpful?
    5 out of 5 stars
    4 October, 2025
    originally posted on influenster.com
    Image

    Works like a charm

    [This review was collected as part of a promotion.] These are some of the best pills I’ve used to get rid of headaches and help with minor back pains. They are not too expensive and packaged to leave at home or take with you on the run.
    shannonh8e78_6904
    Did you find this review helpful?
    5 out of 5 stars
    3 October, 2025
    originally posted on influenster.com
    Image

    No more headache!

    This is the only medicine for headaches. It works every time. Doesn’t upset my stomach either. The tablets aren’t huge and they’re easy to swallow.
    colleena48_9710
    Did you find this review helpful?
    3 out of 5 stars
    30 September, 2025
    originally posted on influenster.com
    Image

    Ok but not the best

    The product is an ok product. Found it not as effective as advil for headaches etc. The value for your money was pretty good the bigger the pkg the better the deal. Would not personally use again I would use an advil product instead.
    marbear4ever_7441
    Did you find this review helpful?

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