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Bonafide Hormonal Mood Swing and Irritability Relief - Serenol - 1 Month Supply - 2 of 4Bonafide Hormonal Mood Swing and Irritability Relief - Serenol - 1 Month Supply - 3 of 4Bonafide Hormonal Mood Swing and Irritability Relief - Serenol - 1 Month Supply - 4 of 4
Bonafide Hormonal Mood Swing and Irritability Relief - Serenol - 1 Month Supply - 1 of 4

Bonafide Hormonal Mood Swing and Irritability Relief - Serenol - 1 Month Supply

$47.99

In Stock

Eligible for registries and wish lists

About this item

Highlights

  • RELIEF FROM HORMONAL MOOD SWINGS: Serenol is a naturally derived solution for the emotional symptoms of hormonal fluctuations and PMS. Its plant-based formula is clinically validated to relieve mood swings, irritability, and uneasiness while also helping to curb cravings.*
  • NO HORMONES & NO HARMFUL SIDE EFFECTS: Serenol is clinically tested and scientifically validated to effectively relieve hormonal mood swings*—without hormones or ingredients known to cause harmful side effects. Individuals allergic to bees, bee products, or bee pollen should not take this product.
  • RESULTS BACKED BY CLINICAL TRIALS: The results of a double-blind, placebo controlled study indicate the ingredients in Serenol significantly reduce mood swings and irritability at month two1. By month three, 77% of women experience PMS relief and 60% reduce irritability and mood swings2.
  • WORKS WITH YOUR BODY, NOT AGAINST IT: As a naturally derived solution, Serenol reduces feelings of irritability and uneasiness with four Swedish botanicals and royal jelly. It also contains chromium picolinate, an essential mineral for metabolic health that reduces caloric intake.*
  • RELIEF THAT WORKS: In a study of 967 Bonafide customers, 71% of women say Bonafide products changed their lives for the better, and 97% say they’d refer the products to a friend suffering from the same problem.
  • 1. Winther K, et al. Curr Ther Res Clin Exp. 2002;63(5):344-353.
  • 2. Results are from an optional, rolling online survey, conducted from July 2016 through November 2017, that included 290 customers who were taking Serenol for at least 3 months. Patients who completed the survey were compensated with a $10 gift card for their opinions about Serenol.
  • These statements have not been evaluated by The Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Description

WHAT TO EXPECT:
Calm that improves over time with best results at month two & beyond¹ ² ³

HOW IT WORKS:
As estrogen levels naturally fluctuate, our body’s ability to regulate mood can be thrown off balance, causing emotional symptoms of PMS and menopause. The naturally derived ingredients in Serenol™ correct this imbalance at the source to restore calm and regulate appetite.*

INGREDIENTS
Amount per two tablets:
Key ingredients: Chromium (as Chromium Picolinate), Purified Cytoplasmic Blend (proprietary Swedish Flower pollen extract (Sérélys) in the form of Pollen + Pistil Extract PI-82, and Pollen Extract GC-FEM), and Royal Jelly.
Other ingredients: Maltodextrin, Calcium Carbonate, Acacia, Isomalt, d-α-tocopheryl succinate (antioxidant), Stearic Acid, Croscarmellose Sodium, Magnesium Stearate, Hydroxypropyl Methylcellulose (alternatively HPMC), Silica, and Polysorbate.
Warning: This product contains royal jelly. Avoid Serenol if you are allergic to bees or bee products.

HOW TO USE:
Take two tablets once per day, with or without food.

¹ Winther K, et al. Curr Ther Res Clin Exp. 2002;63(5):344-353.
Anton et al. Diabetes technol ther. 2008; 10(5) 405-41
² Anton et al’s inclusion criteria did not stipulate women had to have a diagnosis of PMS; rather this study was conducted on healthy, overweight women.
³ Results are from an optional, rolling online survey, conducted from July 2016 through November 2017, that included 290 customers who were taking Serenol for at least 3 months. Patients who completed the survey were compensated with a $10 gift card for their opinions about Serenol. or without food.
Suggested Age: 35 Years and Up
Product Warning: Adult Use Only
Product Form: Tablet
Package Quantity: 60
TCIN: 94892422
UPC: 851678006791
Item Number (DPCI): 245-03-5893
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Shipping details

Estimated ship dimensions: 2.25 inches length x 3.5 inches width x 4.27 inches height
Estimated ship weight: 0.11 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

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17 May, 2026
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Kristina’s review

I’ve only been using this product for about a month and a half. So far, it’s a good product to help with my perimenopausal mood relief.
Kristina B.
Did you find this review helpful?
5 out of 5 stars
16 May, 2026
originally posted on hellobonafide.com

Thank you! Women go through

Thank you! Women go through so much and this helps a lot.
Sally S.
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4 out of 5 stars
27 January, 2026
originally posted on hellobonafide.com

Janicew

I like it because it has helped w “hot flashes” and mood swings. Don’t feel depressed and hot flashes are minimal-tablet smell is not pleasant
Janice W.
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5 out of 5 stars
15 January, 2026
originally posted on hellobonafide.com

Bonafide Review

I think I actually do feel more calm and not so irritable.
Peggy O.
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1 out of 5 stars
15 January, 2026
originally posted on hellobonafide.com

Not sure this product does much of anything for me

I have been taking this for almost 4 mos and I dont feel like it has done anything for my libido at all
Sarah E.
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3 out of 5 stars
12 January, 2026
originally posted on hellobonafide.com

Serenity

I’ve been taking Serenol since May 2025 and haven’t noticed any difference in my moods I stopped HRT July 2023 b/c my sister was dx’d with breast cancer. Thank you for trying
Victoria D.
Did you find this review helpful?
5 out of 5 stars
3 January, 2026
originally posted on hellobonafide.com

Best product and customer service

Customer Service is the best. Also this product works better than painkillers for me. It has made my world livable.
Iman N.
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5 out of 5 stars
18 December, 2025
originally posted on hellobonafide.com

This has been a miracle

This has been a miracle worker. I've tried several different products and none of them worked, but this did in just a week.
Mary K.
Did you find this review helpful?
5 out of 5 stars
12 December, 2025
originally posted on hellobonafide.com

Great product

Can’t confirm but got other benefits too
carla f.
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5 out of 5 stars
4 November, 2025
originally posted on hellobonafide.com

Incredible!!

[This review was collected as part of a promotion.] I'm on my 4th bottle and I am stunned at how well this has worked for me! My husband has noticed the shift which is the biggest positive review of all haha. I started noticing small differences around 4 weeks of taking it but by the end of the 2nd month, it was noticeable. And now, it feels like night and day. The fire that was constantly on a slow burn, that would quickly ignite to a level 5 has mostly been extinguished and life is just so much better and happier! Highly highly recco!!!
Puja R.
Did you find this review helpful?
4 out of 5 stars
4 August, 2025
originally posted on hellobonafide.com

Serenol

[This review was collected as part of a promotion.] I’ve been taking this product for 21 months, and it has a subtle effect that builds over time. It’s not a magic pill, but overall, I’m somewhat satisfied with it. I still experience irritability during PMS, but it’s more manageable than it would be without Serenol – at least that’s my impression.
Kamilla U.
Did you find this review helpful?
5 out of 5 stars
29 July, 2025
originally posted on hellobonafide.com

So glad I found Serenol!

My gynecologist mentioned Bonafide and Serenol in particular to address my issues. I’ve been on it since my early 40’s and am now 50. Feel even keeled, less moody and no hot flashes! Really think it’s been a game changer for me during perimenopause and am so glad I’m on it and grateful it was brought to my attention.
Janine F.
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5 out of 5 stars
17 July, 2025
originally posted on hellobonafide.com

calm and balanced

[This review was collected as part of a promotion.] I was looking for something to help me navigate my rollercoaster emotions and wanted something natural. This product has been a game changer for me, I felt better after 4 short days of taking it. I am now on month 4 and could not be happier, calmer or more balanced. I feel like my self again. Thank you!
Samantha S.
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5 out of 5 stars
10 July, 2025
originally posted on hellobonafide.com

Didn’t know I needed this, very pleased

[This review was collected as part of a promotion.] I didn’t realize how I felt like I was drowning every time I was getting/then on my period—my self esteem would be at an all time low and I felt truly like the biggest disappointment. When I told my PCP, the my gyno, she recommended I try serenol and it really does help. I don’t like the taste but I don’t get depressed anymore; I don’t feel like I’m seeing myself from outside my own body when I’m angry on my period. This has helped me more than I thought it would, I am very very happy with it!
Erica C.
Did you find this review helpful?
5 out of 5 stars
10 June, 2025
originally posted on hellobonafide.com

Definitely helps with PMS Symptoms

[This review was collected as part of a promotion.] I am perimenopausal, and my PMS symptoms are significantly different in terms of when they appear and for how long. Serenol definitely eases my symptoms. My energy levels and mood have improved.
Autumn S.
Did you find this review helpful?
5 out of 5 stars
9 June, 2025
originally posted on hellobonafide.com

Menopausal mood swing relief

[This review was collected as part of a promotion.] I have noticed how my moods can change very drastically within minutes; including when I'm upset or frustrated, I get very emotional. One of many downsides of menopause. Serenol has helped me greatly, with keeping my mood swings at bay and regulating them. I went off of these for a short time, to see if I could manage again without them, and the mood swings went into full swing again. These are truly a relief for me, and I'll remain on them for the time being. I have them delivered monthly, so I don't have to remember to order them (memory loss, another not fun aspect of menopause).
Kandice Y.
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5 out of 5 stars
30 May, 2025
originally posted on hellobonafide.com

So grateful, it has helped

[This review was collected as part of a promotion.] So grateful, it has helped me so much with my mood swings and irritability feeling a lot better
Laura Q.
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4 out of 5 stars
29 May, 2025
originally posted on hellobonafide.com

Great product

[This review was collected as part of a promotion.] I'm pleased with the results I've experienced since taking this product.
Titania A.
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5 out of 5 stars
12 May, 2025
originally posted on hellobonafide.com

Great experience!

[This review was collected as part of a promotion.] I’m a 47 year old perimenopausal woman who’s been struggling with some (expected) hormonal fluctuations the past year or two. The most bothersome symptoms so far have been night sweats and major mood swings. Add 4 kids and nursing school to this equation…and you’ll know why I was begging my gyno for help. Estrogen made things much worse at this point, so she suggested trying this supplement instead. I know the website says it takes about 2 months to be effective, but I would say I felt it begin working about midway through my first week. Then, after a couple months, even more so. It is not a “magic pill” for me that eliminates all mood swings…. BUT it tones them down significantly. It sounds silly…but I always relate the feeling of using Serenol to not having “my feathers ruffled” quite as much as they had been. I just don’t get as upset about the “small” things. My family can ALWAYS tell if I have taken my dose or not. Ha! I would recommend taking in the morning. I have found that taking it later in the day or evening makes it a bit harder to fall asleep. I would (and have) recommended this product to SO MANY people. I am so grateful for this company and this product. I look forward to trying more Bonafide products!
jennie m.
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5 out of 5 stars
5 May, 2025
originally posted on hellobonafide.com

Recommended by both my OB and my therapist

Noticeable difference in mood for the week prior to my period. I appreciate that it's non-addictive and allows me to not have to take a mood stabilizer or anxiety for the sole week I'd need it. It's been such a lifeline. Can't recommend enough!
Nicole
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