New ArrivalsHalloweenChristmasGift IdeasClothing, Shoes & AccessoriesHomeFurnitureElectronicsToysVideo GamesGroceryHousehold EssentialsBeautyBabyKitchen & DiningSchool & Office SuppliesMovies, Music & BooksCharacter ShopSports & OutdoorsBackpacks & LuggagePersonal CareHealthPetsUlta Beauty at TargetTarget OpticalParty SuppliesGift CardsBullseye’s PlaygroundDealsClearanceTarget New Arrivals Target Finds #TargetStyleDía de MuertosStore EventsAsian-Owned Brands at TargetBlack Beyond MeasureMás QueWomen-Owned Brands at TargetLGBTQIA+ ShopTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Diphenhydramine HCl Nighttime Sleep Aid Caplets - 100ct - up&up™ - 2 of 4Diphenhydramine HCl Nighttime Sleep Aid Caplets - 100ct - up&up™ - 3 of 4Diphenhydramine HCl Nighttime Sleep Aid Caplets - 100ct - up&up™ - 4 of 4
Diphenhydramine HCl Nighttime Sleep Aid Caplets - 100ct - up&up™ - 1 of 4

Diphenhydramine HCl Nighttime Sleep Aid Caplets - 100ct - up&up™

$5.99 ($0.06/count)

In Stock

Eligible for registries and wish lists

At a glance

Sponsored

About this item

Highlights

  • Packaging may vary. Same trusted quality
  • Compare to active ingredient in Simply Sleep Caplets
  • 25mg diphenhydramine caplets are ideal for occasional sleeplessness
  • Sleep aid helps you get to sleep so you can wake up refreshed
  • 100ct bottle allows you to be prepared whenever insomnia strikes

Description

If you've counted one too many sheep for your liking, it's time to try Diphenhydramine HCl Nighttime Sleep Aid Caplets from up&up™. Diphenhydramine HCl is a non-habit forming antihistamine that promotes sleepiness, helping you drift off to dreamland in no time. Whether you're traveling or just having trouble getting to sleep at night, these sleep-aid caplets are a reliable way to get to bed so you can wake up ready to face the day.


We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Suggested Age: 12 Years and Up
Health Facts: Contains Diphenhydramine HCl
Product Warning: Consult a doctor if you are pregnant or nursing, consult a doctor if you have a breathing problem, use caution while operating machinery, do not use with other diphenhydramine products, consult a doctor if you have glaucoma, not for children under the age of 12, use caution while driving a motor vehicle
Product Form: Caplet
Primary Active Ingredient: Diphenhydramine
Includes: Sleeping Aid
Package Quantity: 100
TCIN: 13339262
UPC: 311673496015
Item Number (DPCI): 094-01-0289
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

diphenhydramine hcl' '25.0mg

Purpose

Nighttime sleep aid

Uses

Uses for relief of occasional sleeplessness

Directions

Directions Do not take more than directed. See overdose warning adults and children 12 years and over a doctor take 2 caplets at bedtime if needed, or as directed by children under 12 years do not use

Other information

Other information each caplet contains: calcium 25 mg, store between 20-25°C (68-77°F). Avoid high humidity. Protect from light

Inactive ingredients

carnauba wax, colloidal silicon dioxide, croscarmellose sodium, dibasic calcium phosphate dihydrate, fd&c blue #1 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, talc, titanium dioxide' '

Shipping details

Estimated ship dimensions: 1.55 inches length x 1.73 inches width x 3.15 inches height
Estimated ship weight: 0.1 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Q: Is this just Benadryl?

submitted by Jamie - 3 months ago
  • A: Hi Jamie - Thank you for reaching out. We appreciate your interest in Diphenhydramine HCl Nighttime Sleep Aid Caplets. While not identical, Benadryl contains the active ingredient diphenhydramine HCl. Diphenhydramine HCl is the generic name for an antihistamine that can be used to treat allergies, cold symptoms, and also as a sleep aid due to its drowsy side effect. Therefore, Diphenhydramine HCl Nighttime Sleep Aid Caplets likely refers to a product that uses diphenhydramine HCl as its active ingredient to promote sleep, making it similar in function to the sleep-inducing effect of Benadry. Happy Shopping!! - Emma

    submitted byEmma - 2 months ago
    Target staff support

Q: what is the difference between a soft gel and a caplet?

submitted by Munn - 3 years ago
  • A: Hello Munn- Thanks for checking us out. A soft gel is liquid filled pill and a caplet/tablet is a hard solid pill. Hope this helps -Beverly

    submitted byBeverly - 3 years ago
    Target staff support

Q: Did the formula recently change? I know that the design of the box did. I've been taking them for years and have felt sick taking them since the design change. Did the ingredients change at all?

submitted by Sarah Beth - 7 months ago

Frequently bought together

Doxylamine Tablets - 96ct - up&up™

$9.39($0.10/count)
Get a coupon, $10 off a $20 purchase with a flu shot
4.6 out of 5 stars with 303 ratings

Diphenhydramine Hydrochloride Allergy Relief Tablets - up&up™

$3.99 - $7.99
Get a coupon, $10 off a $20 purchase with a flu shot
4.7 out of 5 stars with 2981 ratings

Discover more options

Related Categories

Guests are saying

This sleep aid has garnered positive feedback for its effectiveness in helping guests fall asleep quickly without the grogginess often associated with other sleep medications. Many guests appreciate its non-habit forming nature and the ability to adjust dosages for personalized results. While some have experienced vivid dreams or difficulty waking up, the overall consensus is that it provides a reliable solution for those struggling with sleep issues, making it a valuable addition to any nighttime routine.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.5 out of 5 stars with 543 reviews
    quality: 4.36 out of 5
    value: 4.2 out of 5
    81% would recommend
    79 recommendations
    5 out of 5 stars
    8 September, 2025Verified purchase

    Better than melatonin

    Always had issues sleeping, too much coffee, naps, bad habits, etc. melatonin only keeps me asleep for a few hours, but this one works wonders! Takes about 45/1 hr for it to really kick in. Stays a sleep and feels pretty good in the AM.
    Whitenjng pen
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    23 July, 2025Verified purchase

    Sleep aid

    I have a hard time getting to sleep and this item works just as well as a name brand that cost a lot more. It works for me and the orice is great.
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    28 February, 2025Verified purchase

    Must have for insomnia

    I use these to sleep and they work like a charm.
    Ashley
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    21 February, 2025Verified purchase

    Best sleep ever

    They work great & I have the best dreams. My go to when I can’t fall asleep. It takes about 30 mins to kick in & dreamland here u come :)
    Sha
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    16 October, 2024Verified purchase

    Didnt work

    It did not work and caused uncomfortable grogginess
    S
    3 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    26 September, 2024Verified purchase

    Game changer!

    I have restless legs and was taking Tylenol PM every night to sleep. But after using this I will never go back! It only has the Diphenhydramine and nothing else so I don’t have to worry about liver damage from the nightly use.
    BD
    value: 5 out of 5
    quality: 5 out of 5
    6 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    22 September, 2024Verified purchase

    Works

    Sometimes I can take just a half dose and it helps.
    Mountainview
    quality: 4 out of 5
    value: 4 out of 5
    3 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    12 September, 2024Verified purchase

    Works great!!

    Work great! I take 1 instead of 2 and I’m out!
    Dannnni
    value: 5 out of 5
    quality: 5 out of 5
    4 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    11 September, 2024Verified purchase

    Very helpful!

    Really helps me sleep. I take one about 45 minutes before I go to bed. They work very well for me. If I take 2 I feel groggy the next day. I have a hard time going to sleep but these really help with that.
    ColoradoTarget
    quality: 5 out of 5
    value: 5 out of 5
    4 guests found this review helpful. Did you?
    4 out of 5 stars
    Thumbs up graphic, would recommend
    26 August, 2024Verified purchase

    Trippy drippy dreams.

    Does anyone else have weird dreams involving celebrities being background extras on a tv show that’s all about you, or is it just me?
    RK
    quality: 5 out of 5
    value: 5 out of 5
    8 guests found this review helpful. Did you?
    2 out of 5 stars
    15 August, 2024Verified purchase

    Works but causes weight gain

    Really works, but need to have enough time for a full nights sleep because it will knock you out. And long term use of this medication leads to weight gain. I had unexplained weight gain and finally determined that long term use of an antihistamine causes weight gain. Be aware!
    Lfletch
    6 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    3 August, 2024Verified purchase

    Might be good, might not...

    The bottle was impossible to open. Yes, I pushed down as I twisted the cap, to no avail. I'm not the strongest person, but I shouldn't have to struggle this much to open a bottle.
    Cait0723
    quality: 1 out of 5
    value: 1 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    3 August, 2024Verified purchase

    Good quality

    Just as good as name brand
    Marshmallow
    5 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    18 July, 2024Verified purchase

    Better than melatonin

    I like these better than melatonin. I fall asleep faster and am not groggy at all upon waking.
    Jess
    quality: 5 out of 5
    value: 5 out of 5
    2 guests found this review helpful. Did you?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    13 July, 2024Verified purchase

    Gives me nightmares

    I want to like these, but I honestly can’t tell if they work. I use them on vacations or when I’m really stressed out. They don’t always keep me asleep and I often have wild, scary dreams.
    Lolo
    value: 2 out of 5
    quality: 2 out of 5
    1 guest found this review helpful. Did you?
    2 out of 5 stars
    Thumbs down graphic, would not recommend
    25 June, 2024

    Buy the allergy version for half price

    Just buy the allergy version that is identical but half the price
    stop working in a week
    8 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    24 June, 2024Verified purchase

    Sleep aid

    Works fast but too strong
    Sleep aid
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    4 out of 5 stars
    1 June, 2024Verified purchase

    Sweet Dreams with a Side of Coma

    When it comes to sleep aids, I've tried them all—melatonin, chamomile tea, you name it. So when I found these Nighttime Sleep Aid Caplets, I figured they’d be a gentle nudge into dreamland. Boy, was I wrong. These things are like being hit with a tranquilizer dart meant for a rhino. I took one caplet as directed, 30 minutes before bed. At first, it was lovely—a gentle drift into drowsiness. But then it hit me like a ton of bricks. My eyelids slammed shut, and I was OUT. Not your average sleep, but a deep, coma-like slumber that could withstand a rock concert in my bedroom. Morning came, but I did not. My alarm blared, my cat meowed, the sun shone brightly, yet I remained in a sleep-induced stupor. It was 11 12:15pm by the time I managed to peel myself off the bed, feeling like I'd been through a sleep marathon. Every muscle resisted movement, and my brain was in a fog. Coffee was my savior as I tried to remember what day it was. In conclusion, if you need a solid 12 hours of uninterrupted sleep and don't mind waking up feeling like you've been in a deep freeze, these caplets are your go-to. They're incredibly effective but come with serious morning-after consequences. Ideal for weekends or if you plan to hibernate. I’d say take half a caplet lol. **P.S.:** Side effects may include bizarrely vivid dreams and the inability to wake up on time. Use at your own risk and with a very loud alarm clock!
    abz
    quality: 4 out of 5
    15 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    29 May, 2024

    It's the same as allergy pills

    This is the same as the allergy relief pill but the company is charging you $2 more because it says nighttime. Read the ingredients and don’t be fooled.
    quality: 5 out of 5
    value: 1 out of 5
    7 guests found this review helpful. Did you?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    10 April, 2024Verified purchase

    Yoll definetly go to sleep

    So they work…BUT these thing will put you in a coma basically and it’s hard to wake up the next day and your very drowsy I mean they get you to sleep but idk if I’d recommend the bottle says take two but they are way to strong to be taking two every night
    Sleeping pills
    quality: 3 out of 5
    value: 3 out of 5
    4 guests found this review helpful. Did you?

    Get top deals, latest trends, and more.

    Privacy policy

    Footer

    About Us

    About TargetCareersNews & BlogTarget BrandsBullseye ShopSustainability & GovernancePress CenterAdvertise with UsInvestorsAffiliates & PartnersSuppliersTargetPlus

    Help

    Target HelpReturnsTrack OrdersRecallsContact UsFeedbackAccessibilitySecurity & FraudTeam Member ServicesLegal & Privacy

    Stores

    Find a StoreClinicPharmacyTarget OpticalMore In-Store Services

    Services

    Target Circle™Target Circle™ CardTarget Circle 360™Target AppRegistrySame Day DeliveryOrder PickupDrive UpFree 2-Day ShippingShipping & DeliveryMore Services
    PinterestFacebookInstagramXYoutubeTiktokTermsCA Supply ChainPrivacy PolicyCA Privacy RightsYour Privacy ChoicesInterest Based AdsHealth Privacy Policy