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Nighttime Cold & Flu Relief Liquid - Cherry - 12 fl oz - up&up™ - 2 of 4Nighttime Cold & Flu Relief Liquid - Cherry - 12 fl oz - up&up™ - 3 of 4Nighttime Cold & Flu Relief Liquid - Cherry - 12 fl oz - up&up™ - 4 of 4
Nighttime Cold & Flu Relief Liquid - Cherry - 12 fl oz - up&up™ - 1 of 4

Nighttime Cold & Flu Relief Liquid - Cherry - 12 fl oz - up&up™

$5.49 ($0.46/fluid ounce) was $6.99
New lower price 
save $1.50 (21% reduction)

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About this item

Highlights

  • Packaging may vary. Same trusted quality
  • ACTIVE INGREDIENTS: Active ingredients are Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, and Doxylamine succinate, 12.5 mg. Compare to the active ingredients of Vicks® NyQuil® Cold & Flu.
  • RELIEVES COLD & FLU SYMPTOMS: Nighttime Cold & Flu Relief provides multi-symptom relief by helping with common symptoms such as aches, fever, cough, sneezing and runny nose.
  • NIGHTTIME COLD AND FLU RELIEF: Nighttime Cold and Flu Relief relieves cold and flu symptoms so you can rest through the night.
  • EFFECTIVE: Acts as a pain reliever, fever reducer, cough suppressant and antihistamine.
  • GLUTEN FREE: This product is Gluten Free. Does not contain Pseudoephedrine; contains 10% ALCOHOL.

Description

Compare to Vicks® NyQuil® active ingredients. Are cold and flu symptoms keeping you awake at night? Nighttime Cold & Flu Relief relieves cold & flu symptoms so you can rest. This medicine contains Acetaminophen 650 mg (Pain Reliever/Fever Reducer), Dextromethorphan HBr 30 mg (Cough Suppressant) and Doxylamine Succinate 12.5 mg (Antihistamine). Relieves minor aches and pains, fever, sore throat, cough, runny nose and sneezing. Features a cherry liquid flavor and is Gluten Free.


We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Suggested Age: 12 Years and Up
Health Facts: Contains Dextromethorphan
Active Ingredient Strength Value: 650 Milligrams
Product Warning: Consult a doctor if you have liver disease, consult a doctor if you have a breathing problem, consult a doctor if on a sodium-restricted diet, keep out of reach of children, consult a doctor if taking prescription drugs, ask a doctor if you have prostate issues, consult a doctor if you are pregnant or nursing
Product Form: Liquid
Primary Active Ingredient: Acetaminophen
Package Quantity: 1
Net weight: 12 fl oz (US)
Features: Nighttime Use
TCIN: 16695460
UPC: 311673312018
Item Number (DPCI): 094-14-0149
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

acetaminophen 650.0mg dextromethorphan hbr 30.0mg doxylamine succinate 12.5mg

Purpose

Pain reliever/fever reducer Cough suppressant Antihistamine

Uses

temporarily relieves common cold/flu symptoms: Cough due to minor throat and bronchial irritation sore throat i headache minor aches and pains fever runny nose and sneezing

Directions

take only as directed - see Overdose warning only use the dose cup provided do not exceed 4 doses per 24 hrs adults & children 12 yrs & over 30 mL every 6 hrs children 4 to under 12 yrs ask a doctor children under 4 yrs do not use

Other information

each 30 mL contains: sodium 39 mg store at 20-25°C (68-77°F)

Inactive ingredients

alcohol, anhydrous citric acid, fd&c blue no. 1, fd&c red no. 40, flavor, high fructose corn syrup, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sodium citrate

Shipping details

Estimated ship dimensions: 1.91 inches length x 2.51 inches width x 7.24 inches height
Estimated ship weight: 0.93 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Q: Can we take while pregnant ?

submitted by Yeganeh - 3 years ago
  • A: Hi - That's a great question! For the best answer to your question you should really consult a doctor if you are pregnant or nursing before taking this medication. Happy Shopping!

    submitted byKimbrea - 3 years ago
    Target staff support

Q: Can you take this if you have high blood pressure? Thanks

submitted by SandiB - 4 years ago
  • A: Hello - We recommend that you consult with your medical provider before taking. Thanks!

    submitted byAlexis - 4 years ago
    Target staff support

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Guests are saying

This cold medicine is highly praised for its effectiveness and affordability, often compared favorably to name brand alternatives. Guests appreciate its ability to alleviate symptoms, help with sleep, and provide relief from cough and congestion. Many find it a staple in their medicine cabinet, highlighting its gluten-free labeling and pleasant flavor. Overall, it serves as a reliable option for those seeking effective cold relief without breaking the bank.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.6 out of 5 stars with 835 reviews
    quality: 4.11 out of 5
    value: 4.37 out of 5
    75% would recommend
    65 recommendations
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    29 October, 2025

    Tastes like deatb

    I don’t know if this is gonna work yet but it’s probably the worst thing I’ve ever tasted in my life
    Livye
    quality: 3 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    12 April, 2025Verified purchase

    Nasty taste!

    The new formula is absolutely horrible! Will not be buying this again!
    Chef K
    quality: 1 out of 5
    value: 1 out of 5
    6 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    23 March, 2025Verified purchase

    Old version was way better

    New formula tastes 10x worse. Old version was way better. Please bring it back.
    Pawzilla
    quality: 1 out of 5
    7 guests found this review helpful. Did you?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    20 February, 2025Verified purchase

    New, terrible packaging

    Quality of the medication seems unchanged; however, the packaging has been modified. The bottle is no longer triangular in shape and is not as sturdy. My main complaint, though, is the lid: the plastic is so thin that it's very difficult to pinch effectively at the safety points to twist and remove. I am going to pour the new medication into my old empty bottle.
    Sarah
    quality: 3 out of 5
    value: 4 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    19 February, 2025Verified purchase

    It works

    Less expensive than the competition and it did the same job.
    Lilybee
    quality: 5 out of 5
    value: 4 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    15 February, 2025Verified purchase

    New formula is subpar

    Target recently changed the formula on this product. It is much thinner, and the taste is more harsh. The old formula was much more soothing and had a better flavor. Will be finding a new go-to nighttime cold medicine.
    LadyB29
    quality: 1 out of 5
    value: 1 out of 5
    8 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    4 February, 2025Verified purchase

    Great price

    This is such a great price for 12 oz. Target is really stepping up there game with competitive pricing and during cold and flu season I am absolutely looking to purchase reasonably priced medicine.
    Loni
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    1 February, 2025Verified purchase

    Used to be good

    I used to swear by this stuff. When I was recently sick i had my boyfriend pick this up for me. It was awful. The taste is disgusting. I would always recommend this product but not anymore. Please change the formula back. No longer works.
    Princess
    quality: 1 out of 5
    value: 2 out of 5
    6 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    22 January, 2025Verified purchase

    New formula is horrible

    Usually my go to for colds, I noticed the package changed no big deal but the formula change 🤮 I’ll have to splurge and go for the real NyQuil from now on
    Chels325
    quality: 1 out of 5
    value: 3 out of 5
    7 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    19 January, 2025Verified purchase

    Cold relief plus sleep

    Does the trick. This up & up nightime cold & flu relief helps with all your cold symptoms and helps you sleep at night. Works just like the name brand.
    blacksheep
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    18 January, 2025Verified purchase

    Packaging and formula changed 0/10 do not recommend

    Formula change is AWFUL
    db12
    quality: 1 out of 5
    value: 1 out of 5
    7 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    10 January, 2025Verified purchase

    Does its job!

    Even better than name brand!
    SteelMagnoliasFan
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    9 January, 2025Verified purchase

    Formula change = DISGUSTING

    They made a huge mistake and changed the formula and the new taste is disgusting. I will not buy again and I will definitely be buying the competitors brand.
    Rosiepuff
    quality: 1 out of 5
    9 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    1 January, 2025Verified purchase

    Bad change

    New formula is awful, gross taste. Bring back the old one. I always recommended the target version vs the name-brand. Can’t recommend jt anymore.
    NJ
    quality: 1 out of 5
    value: 3 out of 5
    9 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    1 January, 2025

    Tastes Horrible

    This used to be my go-to cold medicine but the new formula tastes awful! I can’t take it anymore because it tastes that bad.
    Marie
    7 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    31 December, 2024Verified purchase

    Gross taste after changes in dec 2024

    After changing the packaging - and the formula - this went downhill. The new taste is gross. Please bring the older one back !
    Lu
    quality: 1 out of 5
    value: 1 out of 5
    9 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    28 December, 2024Verified purchase

    Yuck

    Changed this medicine and definitely not for the better...it is horrible! Tossed out a full bottle and will not buy anymore
    BR
    7 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    22 December, 2024Verified purchase

    formula change

    This used to be a good product. In December of 2024, they changed the packaging and formula and I can no longer recommend this item. It's downright awful tasting now!
    cf57
    quality: 1 out of 5
    10 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    23 November, 2024Verified purchase

    Great Product!

    Great generic! Just as good as the name brand.
    LoriP
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    5 October, 2024Verified purchase

    ADR

    Works just as well as the name brand at a much better price !
    ADR
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?

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