Similac Soy Isomil Powder Infant Formula - 30.8oz: Kosher, Halal, Easy to Digest, Eye Development
$32.19 ($1.05/ounce) reg $45.99
Sale save $13.80 (30% off)
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Guests are saying
The reviews reflect a diverse range of experiences with this formula, particularly for infants with digestive sensitivities. Many guests found it effective in alleviating issues like gas, fussiness, and spitting up, leading to happier babies. However, some guests reported concerns about constipation and difficulty mixing the formula. Overall, it appears to be a beneficial option for those needing a soy-based formula, especially for babies with lactose intolerance or milk protein allergies.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.5 out of 5 stars with 378 reviews
easy on tummy: 4.29 out of 5
easy to prepare: 4.53 out of 5
quality: 4.47 out of 5
value: 4.24 out of 5
78% would recommend
19 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
17 June, 2026Verified purchase
(no review title)
We tried 5 other formulas (Bobbie, Bobbie Gentle, Kendamil regular, Kendamil goat, Similac Alimentum), and they all caused diarrhea +/- skin rashes. My friend recommended Soy Isomil because her son with cow's milk allergy did well on it, and I'm happy to say this is the holy grail for us, as well. So grateful this formula exists. Yes the poops are very stinky. No, it's not significantly harder to mix — just use a chopstick or a blender ball in a pitcher. On that front: I think Bobbie was the worst, Kendamil was the easiest, Alimentum strangely floated which was also difficult. Yes, she poops less, only about one time a day and a very thick paste, but it doesn't seem nearly as painful as when she had diarrhea. Might take a 2-3 days to get used to it with some gas and stomach upset, but once it adjusts, this is liquid gold. The only challenge is that not every Target stocks the large can, and when I find it, there are usually only 3-5 cans available...so gotta stock up. :)
1 reply from Abbott Nutrition Team team - 3 days ago
We would like to learn more about your baby's experience and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 05008626 when you call. - The Similac Team
1 out of 5 stars
Thumbs down graphic, would not recommend
24 March, 2026Verified purchase
Never again
We hated this formula. Smelled awful. Gave my son hives, a super red butt, and watery poop. He was so uncomfortable. It also caused him to vomit and choke. All this happened in the first 12 hours of being on it.
1 reply from Abbott Nutrition Team team - 3 months ago
We would like to learn more about your baby's experience with Similac Soy Isomil and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer #04969177 when you call. - The Similac Team
1 out of 5 stars
Thumbs down graphic, would not recommend
31 October, 2025Verified purchase
Causes constipation
This formula did not stop my baby from spitting up or throwing up, and it gave him constipation. We switched from Enfamil GentleEase to prevent gas and spit ups, but then my baby stopped pooping as frequently or as much as before. He was so fussy at night and only warm baths would soothe him. We used this formula for about 3 weeks before switching again to Similac Sensitive. Isomil is very expensive, and it isn’t worth the money for me because it doesn’t work for my child.
1 reply from Abbott Nutrition Team team - 8 months ago
We would like to learn more about your baby's experience with Similac Soy Isomil and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04903277 when you call. -The Similac Team
5 out of 5 stars
4 September, 2025Verified purchase
Game changer
My baby has been using this for about a month now. She was very fussy even with similac sensitive (purple). After a few days of switching we have had wonderful fussy-free evenings.
1 reply from Abbott Nutrition Team team - 10 months ago
We would like to learn more about your baby's experience with Similac Sensitive and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04875336 when you call. - The Similac Team
5 out of 5 stars
20 July, 2024
originally posted on similac.com

Soy Beats Dairy!
My baby has done great on this formula from a newborn. For the first three months I only got about 1-2 bottles of breastmilk a day. My baby wasn’t gaining enough weight on breastmilk alone. On this formula she almost never spits up, is not colicky, falls right asleep after nighttime feedings, and is gaining weight nicely. Two negatives - first ingredient is 39% corn syrup and there’s no smaller ready feed options. Please make 6-8 ounce ready feed options!
1 reply from The Consumer Relations Team team - 2 years ago
We would like to learn more about your review and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04682296 when you call.
1 out of 5 stars
Thumbs down graphic, would not recommend
24 April, 2024Verified purchase
I didn't get my order please refund
Did not receive like refund
1 reply from Abbott Nutrition Team team - 2 years ago
We're sorry to hear this happened! We would suggest contacting the Target.com team directly at 800-591-3869 or clicking the 'Target.com Order Experience' topic under the 'Contact Us' section of the website. -The Similac Team
5 out of 5 stars
Thumbs up graphic, would recommend
10 March, 2022Verified purchase
Happy baby happy tummy
I nursed my baby for 9 months. This formula was an easy transition from breast milk. He loved it. Easy on the Tummy and no gas! I’m so pleased.
3 out of 5 stars
Thumbs down graphic, would not recommend
5 March, 2022Verified purchase
Terrible consriparion and gas
This was our fourth formula brand and type to try to supplement BFing due to low supply. We found out our son was lactose intolerant so we switched to soy but came with some side effects: 1. Terrible Constipation causing lack of sleep and restlessness 2. Gas also leading to restlessness 3. Clumpy formula that wouldn’t mix well 4. Some vomiting although this was the reason we switched to soy We are now doing Enfamil nurtamigen and we love it. Finally slept for 2 hours straight.
5 out of 5 stars
Thumbs up graphic, would recommend
3 March, 2022Verified purchase
gentle on tummy
had to substitute because of alimentum recall. this is better thn any other formula if your child is allergic to cow's milk protein. great for sensitive tummy, reduced colic n gas significantly.
5 out of 5 stars
13 January, 2022Verified purchase
Fantastic price
My son can only take Similac Soy. Ordered these cans since Dec. 12, was on back order but Target got them here by Jan. 06. Only 2 days off from the initial delivery time, which isn't too bad considering the holiday mail rush. Very satisfied with my order and will be ordering more since the price is economical compared to how much it is being sold here on Guam.
5 out of 5 stars
11 January, 2022
originally posted on similac.com

The best!!
My baby girl is a month old. She started off with Similac pro advance in the hospital and she was one fussy baby and couldn't handle it well. Switched her to Similac Isomil and it was like a whole new baby! She sleeps through the night and not fussy and gassy all day. Tried Gerber good start soy and it did not go well with her tummy either. Thank God for this formula, I have one happy, healthy baby.
1 reply from The Similac Team team - 4 years ago
We're so glad your little one is doing well on Similac Soy Isomil and we would like to learn more about her troubles with Similac Pro-Advance. Please give our team a call at 800-850-7677, M-F from 8:30am-5pm, EST & reference customer# 04201003. We hope to hear from you soon!
5 out of 5 stars
Thumbs up graphic, would recommend
8 January, 2022Verified purchase
Love
I use this formula for my daughter who has a lactose intolerance and it is easy on her belly
3 out of 5 stars
17 December, 2021
originally posted on similac.com

Constipation
I really liked this formula, my daughter has finally found something that doesn’t trigger her heart burn as much. But since we started on this brand, she’s been constipated, little to no bowel movement every 2-3 days. Also, there’s lots of rumbling in the stomach when she’s feeding, not sure what that is. I really wish she didn’t have constipation because it really was working out for her.
1 reply from The Similac Team team - 5 years ago
We would like to learn more about your baby's experience with Similac Soy Isomil and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, EST & be sure to reference customer# 04187193 when you call.
5 out of 5 stars
21 November, 2021Verified purchase
Great
The right formula. This is a mos t expensive lesson $215.00 later
5 out of 5 stars
Thumbs up graphic, would recommend
9 November, 2021Verified purchase
Easy on babies tummy
Switched from Similac Advanced, to this soy kind and it’s so much better for my daughter. Easy on her stomach, she has much less gas and spit up from this formula.
1 reply from Abbott Nutrition Team team - 5 years ago
Thanks for reaching out. We're glad your little one is doing well on Similac Soy Isomil and we would like to learn more about her troubles with Similac Advance. Feel free to give us a call when you have a few minutes to spare: 800-850-7677, M-F from 8:30am-5pm, EST & reference customer# 04167169. -The Similac Team
4 out of 5 stars
Thumbs up graphic, would recommend
19 August, 2021Verified purchase
Amazing Formula
Breastfeeding didn’t work out for my son & I. Hospital started him on pro advance but I realized he was very gassy & seemed uncomfortable. We switched to soy & he’s been fine since! 9 months later & we’ve never had problems. My only issue w Target is the price. In store I never have an issue with anyone adjusting the price, everyone is super nice about it. But it will be helpful to change the price online so people can order for delivery.
1 reply from Abbott Nutrition Team team - 5 years ago
We would like to learn more about your baby's experience with Similac Pro-Advance and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, EST & be sure to reference customer# 04120229 when you call. -The Similac Team
4 out of 5 stars
Thumbs up graphic, would recommend
8 August, 2021Verified purchase
no longer constipated
helped my 6 month old poop
5 out of 5 stars
2 August, 2021
originally posted on similac.com

Great!!
So my daughter is six weeks old. The hospital started her out on pro advance. She did not do so well with it. A lot of gas and lot of cramping very grumpy.. a lot of crying and fussy after feedings. After four weeks complaining about this issue her pediatrician moved her to soy. She’s doing very well with the soy in fact she loves it and we’ve had no more issues with the fussiness, cramping and being grumpy. For me to stop and do a review us serious I know a lot of moms want to know especially first time moms
1 reply from The Similac Team team - 5 years ago
We're glad your little one is doing well on Similac Soy Isomil and we would like to learn more about her troubles with our other Similac infant formulas. Please give our team a call at 800-850-7677, M-F from 8:30am-5pm, EST & reference customer# 04107519. We hope to hear from you soon!
5 out of 5 stars
4 July, 2021
originally posted on similac.com

No spit ups
I switched to this lactose free option 5 days ago and my baby has not spit up at all. She's happier, less fussy and her bowel movements are more consistent. Great decision to switch her from cows milk
5 out of 5 stars
Thumbs up graphic, would recommend
21 May, 2021Verified purchase
Game changer
This formula helped sooth my baby tummy issues. He’s able to keep it down and not be colicky.