Depend Night Defense Incontinence Underwear - Women's - Medium
$21.99 ($0.92/count)See 2 deals for this item
SizeM
Count24ct
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Available deals
$5 Target GiftCard with 3 select menstrual care items
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- Highly rated$14.99 - $49.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 2947 ratings
- Highly rated$12.99 - $53.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.5 out of 5 stars with 5670 ratings
- $14.99 - $49.99$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 1352 ratings
- $14.99 - $50.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 1392 ratings
- Highly rated$14.99 - $49.49Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 2897 ratings
- $15.89 - $56.99$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 1143 ratings
- Highly rated$12.99 - $53.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.5 out of 5 stars with 5670 ratings
- $15.89 - $56.99$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 1143 ratings
- Highly rated$14.19 - $49.99$5 Target GiftCard with 3 select menstrual care items on select items4.5 out of 5 stars with 3097 ratings
Frequently bought together
- Highly rated$12.99 - $53.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.5 out of 5 stars with 5670 ratings
- Highly rated$12.99 - $53.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.5 out of 5 stars with 5670 ratings
- Highly rated$15.89 - $56.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 2829 ratings
- Highly rated$15.99 - $56.99$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 8086 ratings
- Highly rated$15.99 - $56.99$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 8086 ratings
- Bestseller$18.29$5 Target GiftCard with 3 select menstrual care items3.9 out of 5 stars with 558 ratings
- $21.49Coupon: $2.50 off+ 1 deal4.6 out of 5 stars with 1050 ratings
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- Highly rated$15.89 - $56.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 2829 ratings
- Highly rated$12.99 - $53.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.5 out of 5 stars with 5670 ratings
- Highly rated$14.19 - $49.99$5 Target GiftCard with 3 select menstrual care items on select items4.5 out of 5 stars with 3097 ratings
- Highly rated$12.69 - $14.19$5 Target GiftCard with 3 select menstrual care items on select items4.1 out of 5 stars with 2211 ratings
- Highly rated$12.99 - $53.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.5 out of 5 stars with 5670 ratings
- Highly rated$14.99 - $49.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 2947 ratings
- $13.99 - $21.49$5 Target GiftCard with 3 select menstrual care items4.5 out of 5 stars with 1257 ratings
- Bestseller$14.19 - $49.99$5 Target GiftCard with 3 select menstrual care items on select items4.5 out of 5 stars with 3097 ratings
- $15.89 - $56.99$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 1143 ratings
- Highly rated$14.99 - $49.49Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 2897 ratings
- $14.99 - $50.99Lower price on select items$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 1392 ratings
- $15.99$5 Target GiftCard with 3 select menstrual care items4.4 out of 5 stars with 1606 ratings
- $14.99 - $49.99$5 Target GiftCard with 3 select menstrual care items on select items4.6 out of 5 stars with 1352 ratings
- $13.99 - $21.49$5 Target GiftCard with 3 select menstrual care items4.5 out of 5 stars with 1039 ratings
- $13.99 - $21.49$5 Target GiftCard with 3 select menstrual care items4.5 out of 5 stars with 1210 ratings
- $13.99 - $21.49$5 Target GiftCard with 3 select menstrual care items4.5 out of 5 stars with 1257 ratings
Related Categories
4.6 out of 5 stars with 2829 reviews
comfort: 4.51 out of 5
effectiveness: 4.4 out of 5
quality: 4.37 out of 5
value: 4.12 out of 5
81% would recommend
116 recommendations
5 out of 5 stars
19 June, 2026
originally posted on influenster.com

Love 😍
[This review was collected as part of a promotion.] I can say that this is one product that put a smile on my face. I was on my monthly and used this as extra for when I'm sleeping and it worked 100. Wearing it was super comfortable. No bulking or movement. I highly recommend
4 out of 5 stars
19 June, 2026
originally posted on influenster.com

Just Right
[This review was collected as part of a promotion.] These Night Defense Depends are a game changer for bladder leaks and your menstrual cycle. They protect very well and are true to size. I have used these several times and you will have absolutely no odor or bunching.
5 out of 5 stars
19 June, 2026
originally posted on influenster.com

Super comfortable and absorbent
[This review was collected as part of a promotion.] My grandma usually used incontinence pads but we wanted to try something new and these were the perfect solution. True to size with a comfortable fit. I personally think they’re less noticeable than the really big thick pads she normally uses and they’re way more absorbent. She’s been using them for several days and has had no leaks at all. So far so good.
5 out of 5 stars
18 June, 2026
originally posted on influenster.com

Great for your period
[This review was collected as part of a promotion.] Best product for your period, it’s feel so comfortable and really easy to use, maintain your area dry and without odor, it really great specially for the nights.
4 out of 5 stars
18 June, 2026
originally posted on influenster.com

A great over night help in staying dry
[This review was collected as part of a promotion.] For all those who have a need for help in staying dry particularly at night I want to recommend Depend products but especially their Night Defense overnight underwear. These are soft ,comfortable and do not " bunch up" even if you are a restless sleeper. They keep you dry and odor free all night ,due to an absorbent core .They appear to fit true to size at the waist ,legs and bottom .Because they feel / look more like cloth underwear they are also quieter than some hygiene products I have used in the past.Recommend to family and friends who need a little help staying dry.
5 out of 5 stars
18 June, 2026
originally posted on influenster.com

Comfortable and do their job!
[This review was collected as part of a promotion.] Depends fit nicely with a pretty design for women. They have good coverage to prevent leakage. They are comfortable and almost feel like your normal panties.
5 out of 5 stars
18 June, 2026
originally posted on influenster.com

Perfect for periods!
[This review was collected as part of a promotion.] These overnight underwear are so comfortable to wear during my period. I don't have to worry about leaks or ruining my cute underwear. There's no fragrance and they don't automatically scream "diaper".
5 out of 5 stars
17 June, 2026
originally posted on influenster.com

Amazing Coverage
[This review was collected as part of a promotion.] I love how great it works to hold for hours. I love how comfortable it fits my whole body. The size fits my thick areas great. The amount of procduct is kust rigjt for lesl coverage.
5 out of 5 stars
17 June, 2026
originally posted on influenster.com

Night Defense.
[This review was collected as part of a promotion.] I was gifted this product in exchange for my honest opinion and I am very excited to receive it. These underwear are very comfortable and breathable. They are great to use at night. The product protects against nighttime leakage. The item is easy to wear. It is disposable and works great. I definitely would recommend this dependable product.
4 out of 5 stars
17 June, 2026
originally posted on influenster.com

Keeps me dry feeling
[This review was collected as part of a promotion.] The depends adult briefs fits right for the size. Keeps the skin dry. They do feel a little to bulky for me in the crotch area . They are durable and don't come apart.
4 out of 5 stars
16 June, 2026
originally posted on influenster.com

Secured and clean
[This review was collected as part of a promotion.] Strong protection movement couldn’t really tell they were there discreetness is good as well as discretion no bulkiness at all. Works well fir what it’s supposed to do
4 out of 5 stars
16 June, 2026
originally posted on influenster.com

Comfortable fit!
[This review was collected as part of a promotion.] The disposable undergarments are very comfortable and lightweight. The fit is roomy, but hugs your bottom to be worry-free from any leakage problems. The markings on the back make it fool-proof to wear them right. The only downside is they tend to bunch up with extended wear.
5 out of 5 stars
16 June, 2026
originally posted on influenster.com

Happy with my protective underwear 🩲
[This review was collected as part of a promotion.] I am happy with my protective underwear, since with the pregnancy I have been having urine leaks at night and this has protected me from going directly to the mattress, being able to sleep more peacefully like this, they are very comfortable, soft and of the size they correspond, they have definitely been very helpful to me
5 out of 5 stars
15 June, 2026
originally posted on influenster.com

Great womens protective underpants
[This review was collected as part of a promotion.] Really great quality women’s pull on underwear to help with leaks. You would never know someone had these on, they are a neutral nude color and fit well like a pair of underwear! They offer great protection and very easy to remove and dispose.
5 out of 5 stars
15 June, 2026
originally posted on influenster.com

Nighttime reassurance
[This review was collected as part of a promotion.] A great soft feel overnight underwear. Designed for the best fit, sizing is right on. These are great for postpartum use also! No noise and doesn’t feel like wearing a diaper.
5 out of 5 stars
15 June, 2026
originally posted on influenster.com

A comfortable night.
[This review was collected as part of a promotion.] The depends nighttime underwear are very comfortable. The fit felt secure and had enough padding that I felt protected by how absorbent they were. I didn't feel constricted, I felt the size was right.
4 out of 5 stars
15 June, 2026
originally posted on influenster.com

Great incontinence product
[This review was collected as part of a promotion.] These are a mighty product with breathable material and fit with great discretion. My oldest daughter utilizes these for protection and absorption as she has a bladder disorder and needs the support particularly at night. I will say storing the pads after use they must be removed as soon as possible because the odor block is good for the night time. You definitely can't leave them in the trash for later. Other than that they are great.
5 out of 5 stars
15 June, 2026
originally posted on influenster.com

Depend Underwear
[This review was collected as part of a promotion.] I really like these Depend Night Defense Baldder Leak Underwear. It fits just just right. It is nice and stretchy. They are comfortable to wear all night. They are very absorbent and keep odors at bay.
5 out of 5 stars
15 June, 2026
originally posted on influenster.com

Pads could never!
[This review was collected as part of a promotion.] I feel like my review is going to be a little different. I did not really use these specifically for incontinence but rather postpartum. They were a lifesaver. I never noticed any unpleasant odors or wetness. They were very discreet underneath my clothes- to be fair I really wasn't wearing skin tight clothing either. Seriously, the best part was peace of mind. I never once worried about leaks or waking up to a crime scene. Unlike pads that can shift or leak, betraying you at your most vulnerable, these did their job. Postpartum recovery is hard and emotional enough, thankfully you have one less thing to worry about with Depends.
5 out of 5 stars
14 June, 2026
originally posted on influenster.com

Works well
[This review was collected as part of a promotion.] These diapers are the perfect size. It holds a good amount of a decent amount of time. It’s super comfortable and discreet. You can’t tell it’s a diaper on.