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Ibuprofen PM Caplets - Diphenhydramine (NSAID) - 20ct - up&up™ - 2 of 4Ibuprofen PM Caplets - Diphenhydramine (NSAID) - 20ct - up&up™ - 3 of 4Ibuprofen PM Caplets - Diphenhydramine (NSAID) - 20ct - up&up™ - 4 of 4
Ibuprofen PM Caplets - Diphenhydramine (NSAID) - 20ct - up&up™ - 1 of 4

Ibuprofen PM Caplets - Diphenhydramine (NSAID) - 20ct - up&up™

$3.99

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About this item

Highlights

  • ACTIVE INGREDIENTS: This nighttime pain relief medicine contains ibuprofen 200 mg, a pain reliever (NSAID), and diphenhydramine citrate 38 mg, a nighttime sleep-aid. Compare to the active ingredients of Advil PM.
  • NIGHTTIME SLEEP AID: Ibuprofen PM contains a combination of a nighttime sleep-aid and a pain reliever/NSAID (nonsteroidal anti-inflammatory drug) that provides relief of occasional sleeplessness when associated with minor aches and pains.
  • PAIN RELIEF: Muscles, bones and joints are vulnerable targets for pain to attack. Pain may begin with an injury or illness.
  • FOR ADULTS AND CHILDREN 12 YEARS AND OVER: Ibuprofen PM tablets are used as a pain reliever (NSAID) and nighttime sleep-aid for adults and children 12 years and over.
  • GLUTEN FREE: Ibuprofen PM are coated caplets (capsule-shaped tablets) in a safety sealed bottle. This product is gluten free.

Description

Compare to the active ingredients of Advil PM. Minor aches and pains shouldn’t interfere with a good night's sleep. Find relief and catch some Z's with Ibuprofen PM. This pain reliever and nighttime sleep-aid relieves occasional sleeplessness when associated with minor aches and pains that are keeping you awake at night. Ibuprofen PM contains a combination of ibuprofen 200 mg, a pain reliever/NSAID (nonsteroidal anti-inflammatory drug) and diphenhydramine citrate 38 mg, a nighttime sleep-aid that work hard to fight minor aches and pains and to help you fall asleep. For adults and children 12 years and over. Gluten free.
Suggested Age: 12 Years and Up
Health Facts: Contains Diphenhydramine Citrate
Active Ingredient Strength Value: 38 Milligrams
Product Warning: Consult a doctor if you have heart disease, consult a doctor if you have high blood pressure, do not use before heart surgery
Product Form: Caplet
Primary Active Ingredient: Diphenhydramine
Package Quantity: 20
TCIN: 94770464
UPC: 370030118373
Item Number (DPCI): 094-01-3456
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Shipping details

Estimated ship dimensions: 3.18 inches length x 1.73 inches width x 1.69 inches height
Estimated ship weight: 0.07 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.
Download the safety data sheet (PDF)
This document lists product hazards, safety info and any potential ill effects on human health. All info has been collected and verified by the manufacturer.

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25 April, 2026
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Effective for night time relief

[This review was collected as part of a promotion.] Sometimes I need something to help with inflammation or discomfort at the end of the day, so this is a great option that helps me sleep too. It doesn’t make me crash, it’s just gentle easing into sleep and I wake up in the morning without feeling groggy. It’s easy for me to swallow with no weird taste.
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5 out of 5 stars
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Works well, but pulls are big

[This review was collected as part of a promotion.] This PM ibuprofen has been helpful for my knee pain. The pills are quite large so I have to break them in half. The bottle is a nice size. But half empty, so not sure why it’s the size it it. Lid doesn’t open unless you push down and twist so it’s a good safety feature with kids around. Instructions are easy to understand.
soziehh
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5 out of 5 stars
Thumbs up graphic, would recommend
25 April, 2026
originally posted on Sozie
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Quality ibuprofen at a great price

[This review was collected as part of a promotion.] This ibuprofen PM has worked well for me. I’ve used Target’s up&up brand medication for some time and it has always worked as advertised. This version is no different. The pill itself was easy to handle and the packaging was simple to figure out. I have taken this right before bedtime a few times and it helps me stay asleep through the night.
sozieforrest44
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5 out of 5 stars
Thumbs up graphic, would recommend
22 April, 2026
originally posted on Sozie
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Reliable low-dose relief for my back pain

[This review was collected as part of a promotion.] I’ve found that 200 mg of ibuprofen works perfectly for me. It helps relieve my back pain after playing spots. I always make sure to take it with food. The pack comes with 20 caplets, which makes it convenient to carry with me. So far, I’m really happy with it and would definitely recommend it!!!!!!
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5 out of 5 stars
Thumbs up graphic, would recommend
19 April, 2026
originally posted on Sozie
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A great minor pain reliever

[This review was collected as part of a promotion.] This is a reliable go to for me whenever I have pain that makes it difficult for me to fall and stay asleep. It helps with headaches, body aches, and soreness while helping me relax. The pill is very easy to swallow, it has no after taste, and works just like the name brand. Overall, it’s a practical, budget-friendly option that gets the job done.
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