New ArrivalsEasterClothing, Shoes & AccessoriesHomeKitchen & DiningOutdoor Living & GardenFurnitureGroceryHousehold EssentialsBabyBeautyPersonal CareHealthWellnessBackpacks & LuggageSports & OutdoorsToysElectronicsVideo GamesMovies, Music & BooksSchool & Office SuppliesParty SuppliesGift IdeasGift CardsPetsUlta Beauty at TargetShop by CommunityTarget OpticalDealsClearanceTarget New ArrivalsRoller Rabbit x TargetEasterHome Decor Ideas & TrendsTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Target Circle™Target Circle™ CardTarget Circle 360™Registry & Wish ListWeekly AdFind Stores

Easter is this Sunday, April 5

Easter is this Sunday, April 5

Easter is this Sunday, April 5

Get everything you need to celebrate. Shop Easter now

Get everything you need to celebrate. Shop Easter now

Get everything you need to celebrate. Shop Easter now

Nighttime Cold & Flu Relief Softgels - 24ct - up&up™: Contains Acetaminophen, Paraben-Free, Alcohol-Free - 2 of 4Nighttime Cold & Flu Relief Softgels - 24ct - up&up™: Contains Acetaminophen, Paraben-Free, Alcohol-Free - 3 of 4Nighttime Cold & Flu Relief Softgels - 24ct - up&up™: Contains Acetaminophen, Paraben-Free, Alcohol-Free - 4 of 4
Nighttime Cold & Flu Relief Softgels - 24ct - up&up™: Contains Acetaminophen, Paraben-Free, Alcohol-Free - 1 of 4

Nighttime Cold & Flu Relief Softgels - 24ct - up&up™: Contains Acetaminophen, Paraben-Free, Alcohol-Free

$5.99

In Stock

Eligible for registries and wish lists

Save 5% every day

With Target Circle™ Card

At a glance

About this item

Highlights

  • Packaging may vary. Same trusted quality
  • "This is an age restricted item and will require us to take a quick peek at your ID upon pick-up"
  • ACTIVE INGREDIENTS: This product contains acetaminophen (pain reliever and fever reducer), dextromethorphan HBr (cough suppressant) and doxylamine succinate (antihistamine) which compares to the active ingredients in Vicks® NyQuil® Cold & Flu.
  • POWERFUL NIGHTTIME RELIEF: This cold and flu medicine provides multi-symptom relief of common cold and flu symptoms while you sleep.
  • PAIN RELIEVER AND FEVER REDUCER: Relieves sore throat, minor aches and pains and reduces fever associated with the common cold and flu.
  • COUGH SUPPRESSANT: This nighttime cold and flu relief medicine helps to relieve coughing so you can rest.
  • ANTIHISTAMINE: Helps relieve runny nose and sneezing associated with the common cold and flu.

Description

Compare to Vicks® NyQuil® Cold & Flu active ingredients. Get powerful nighttime relief with Nite Time Cold & Flu Relief Softgels. This cold and flu medicine helps relieve major flu symptoms so you can rest. This product contains a pain reliever, fever reducer, cough suppressant and antihistamine for multi-symptom relief of aches, fever, sore throat, sneezing, runny nose and cough. This product is gluten free and alcohol free. Does not contain pseudoephedrine.


We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Trial/Mini/Travel Size: Yes
Suggested Age: 12 Years and Up
Health Facts: Petroleum-Free, Contains Dextromethorphan, Contains Pain Reliever, Contains Antihistamine, Alcohol-Free, Contains Acetaminophen, Contains Doxylamine Succinate, Paraben-Free, Gluten-Free
Active Ingredient Strength Value: 325 Milligrams
Product Warning: Consult a doctor if you are pregnant or nursing, consult a doctor if you have a medical condition prior to use, Contains Acetaminophen, consult a doctor if taking prescription drugs, use caution while operating machinery, do not use if you are taking an MAOI
Product Form: Softgel
Primary Active Ingredient: Acetaminophen
Package Quantity: 24
Net weight: .14 Pounds
Features: Nighttime Use
TCIN: 11016438
UPC: 349483694246
Item Number (DPCI): 094-14-0059
Origin: Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

acetaminophen' '325.0mg dextromethorphan hbr' '15.0mg doxylamine succinate' '6.25mg

Purpose

Pain reliever/fever reducer Cough suppressant Antihistamine

Uses

temporarily relieves common cold/flu symptoms: Cough due to minor throat & bronchial irritation sore throat headache minor aches & pains fever runny nose & sneezing

Directions

take only as directed do not exceed 4 doses per 24 hrs adults & children 12 yrs & over 2 softgeswith water every 6 hrs children 4 to under 12 yrs ask a doctor children under 4 yrs ask a doctor

Other information

store at room temperature

Inactive ingredients

,fd&c blue #1, fd&c yellow # 10, gelatin, glycerin, polyethylene glycol, povidone, propylene głycol, purified water, shellac, sorbitol sorbitan solution, titanium dioxide.,

Shipping details

Estimated ship dimensions: 4.53 inches length x 3.35 inches width x 1.18 inches height
Estimated ship weight: 0.132 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: Are these still gluten free? New labeling on product does not show gluten free!!! Very important for people with celiac. Thanks!

submitted by ElleEa - 1 year ago

  • A: Is this Gluten Free? The Gluten Free label isn’t on here anymore? I have celiac, so I need to be careful.

    submitted byAsking 2025 - 1 year ago

  • A: Hello ElleEa - We appreciate your concern on this item. This product has an unqualified independent third-party certification, or carries an on-pack statement relating to the finished product being gluten-free. Happy shopping at Target – Alvin

    submitted byAlvin - 1 year ago
    Target staff support

Q: What is the adult dosage

submitted by James C - 6 months ago

  • A: Hi James C - Thank you for your question. As mentioned in the directions ,for adults & children 12 yrs & older, take 2 softgels with water every 6 hrs. I hope this helps. - Kate

    submitted byKate - 5 months ago
    Target staff support
See all questions (2)

Additional product information and recommendations

Discover more options

Guests also viewed

4.7 out of 5 stars with 641 reviews
quality: 4.55 out of 5
value: 4.7 out of 5
88% would recommend
27 recommendations
2 out of 5 stars
Thumbs down graphic, would not recommend
23 December, 2025Verified purchase

Woozy

This didn’t help my cough at all, I think it did help me drift off in between coughing though. I still woke up every hour or more coughing and felt very woozy from the doxy haha. I have honestly never found a cough suppressant that actually works for me so maybe it’s my genetics.
Diem55
quality: 3 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
1 December, 2025Verified purchase

Sleep Aide

I can go without the day version but the night version allows for restful sleep and smoother wakeup.
Ross
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
25 June, 2025Verified purchase

As good as the name brands

This is my go to when I get sick. Great price and works just as good as the expensive brands.
Andie22
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
10 June, 2025Verified purchase

Great Relief

Works great and helped reduce my symptoms!
POM
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
8 June, 2025

Great alternative

Compared to the name brand at a way lower price. Works just the same. These tend to go out of stock before the name brand ones do 😆
Alysha
quality: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
16 March, 2025Verified purchase

Recommend

Whenever I feel a sinus headache starting before bedtime, I take I liquid capsule. They are rather large but do the trick for a reasonable price.
Nana Loves Summer
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
23 February, 2024Verified purchase

Relief

It helps at night but don't take if you got high blood pressure get with your Dr and ask want you can take
Noni
2 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
31 December, 2023

Pill not as shown!

The photo of the pill size is wrong! I bought this because it claims the pill size to be what is advertised on the box. I always relied on Up & Up brands. This time, it’s false advertisement. Trying to swallow a huge pill when you have a sore throat and not feeling well isn’t pleasant.
JGA
value: 1 out of 5
quality: 1 out of 5
2 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
27 December, 2023Verified purchase

Good

I like it Relieve coughing
Allisa
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
14 December, 2023Verified purchase

generic >>>

i always buy generic over brand when it comes to medicines: it is quite literally the same thing. a lot cheaper than publix's private label too.
garfunkle
quality: 5 out of 5
value: 5 out of 5
2 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
21 November, 2023Verified purchase

Same as nyquil just cheaper!

Wouldn’t be able to tell the difference between this and NyQuil except for the price difference
Cait2428
quality: 5 out of 5
value: 5 out of 5
2 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
24 September, 2023Verified purchase

Very comparable to leading name brand

Needed to grab something affordable when the whole household caught something. This did the trick despite being cheaper than name brand! Worked just as expected & really couldn’t tell the difference.
helen
quality: 5 out of 5
value: 5 out of 5
3 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
18 September, 2023Verified purchase

This is it!

Work just as good as the name brand stuff! Wouldn't buy anything else.
PepeSilvia
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
12 September, 2023Verified purchase

Perfect cold blaster!

Helped reduce my cold symptoms and a good price!
Anderson
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
26 August, 2023

Love this brand!

Works just as good if not better than the name brand!
mswright29
1 guest found this review helpful. Did you?
5 out of 5 stars
2 February, 2023Verified purchase

Works!

This works just as well as the big name brand at a fraction of the cost!
Crisvw
1 guest found this review helpful. Did you?
4 out of 5 stars
Thumbs up graphic, would recommend
17 December, 2022Verified purchase

Had me Zonked 10/10

Helped with my symptoms and had me taking fat naps the whole time I was sick. It was great. Just wish there wasn’t food coloring in it.
Targetlady98
quality: 4 out of 5
value: 5 out of 5
9 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
10 December, 2022

Great

works as described. helped me sleep
Alli
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
22 November, 2022

Works quickly

Works quickly. And it's cheap.
Sbran
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
16 November, 2022Verified purchase

This works

I was a little unsure if this would work. They worked I will try the day version too
Christine
value: 5 out of 5
quality: 5 out of 5
1 guest found this review helpful. Did you?

Get top deals, latest trends, and more.

Privacy policy

Footer

About Us

About TargetCareersNews & BlogTarget BrandsBullseye ShopSustainability & GovernancePress CenterAdvertise with UsInvestorsAffiliates & PartnersSuppliersTargetPlus

Help

Target HelpReturnsTrack OrdersRecallsContact UsFeedbackAccessibilitySecurity & FraudTeam Member ServicesLegal & Privacy

Stores

Find a StoreClinicPharmacyTarget OpticalMore In-Store Services

Services

Target Circle™Target Circle™ CardTarget Circle 360™Target AppRegistrySame Day DeliveryOrder PickupDrive UpFree 2-Day ShippingShipping & DeliveryMore Services
PinterestFacebookInstagramXYoutubeTiktokTermsCA Supply ChainPrivacy PolicyCA Privacy RightsYour Privacy ChoicesInterest Based AdsHealth Privacy Policy