Tylenol Cold+Flu Severe Day/Night Caplets - Acetaminophen - 24ct: 325mg Strength
$7.69
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$1.79 - $13.79
$15 Target GiftCard with $50 household items purchase
4.7 out of 5 stars with 8265 ratings
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Guests are saying
This product is a reliable choice for managing cold and flu symptoms, offering both daytime and nighttime relief in one convenient package. Guests appreciate its effectiveness in alleviating symptoms like fever, body aches, and congestion, while the easy-to-swallow gel pills make it accessible for everyone. The dual packaging is particularly praised for its practicality, ensuring that guests can find the right medication when they need it most. Overall, it is a staple for many during the colder months.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.7 out of 5 stars with 1596 reviews
quality: 4.3 out of 5
value: 4.41 out of 5
76% would recommend
42 recommendations
1 out of 5 stars
Thumbs down graphic, would not recommend
15 March, 2026Verified purchase
Did Not Work
This use to be my go to medication for a cold. Unsure what happened, but it didn’t work at all! I’m very disappointed, this was a waste of money.
1 out of 5 stars
8 March, 2026Verified purchase
Didn't receive this item!!!
Wasn't in the box with everything else so you need to send it or give me a refund!!
1 out of 5 stars
Thumbs down graphic, would not recommend
1 March, 2026
(no review title)
never received on Feb 26
5 out of 5 stars
Thumbs up graphic, would recommend
17 February, 2026Verified purchase
Very good to travel with when you have all allergies two medication.
We have family members that are allergic to many medication’s Tylenol brand is a medication for them. We have been buying the day and night combo pack for many years, we make sure it is in our toiletry kit when we travel. Very effective. Nighttime capsules work very well.
4 out of 5 stars
13 February, 2026
originally posted on influenster.com

Relives your flu symptoms
The day time pill helps to alleviate your symptoms and the night time pill helps you get the much needed rest so you can recover. I definitely recommend giving a try if you don’t like the liquid
1 out of 5 stars
Thumbs down graphic, would not recommend
8 February, 2026Verified purchase
Doesn't work at all for cold and flu symptoms
If I were taking regular Tylenol, I would receive the same alleviation of my symptoms, which include cough, sore throat, and sinus congestion. That is to say, there is no relief. It’s so bad, that I’m wondering how long after the manufacture date it’s actually good. This has a manufacture date of 2023.
5 out of 5 stars
Thumbs up graphic, would recommend
6 January, 2026Verified purchase
Highly recommend
Helped me feel SO much better quick!
1 out of 5 stars
Thumbs down graphic, would not recommend
5 January, 2026
Did nothing!
Did not help with coughs or mucus Just a glorified pain reliever
5 out of 5 stars
4 January, 2026
originally posted on influenster.com

Good for head cold
This medication has been helpful for sinus headaches and pressure. The dosage was clear on the packaging. Easily taken with smooth texture. Would use again.
5 out of 5 stars
Thumbs up graphic, would recommend
31 December, 2025
Magic flu medicine!
This is the best flu medicine I've ever used and I've tried them all. My go to when I'm feeling crappy!
4 out of 5 stars
18 November, 2025Verified purchase
(no review title)
My go too cold /flu medicine
5 out of 5 stars
5 November, 2025
originally posted on influenster.com

Amazing
This medicine is the one that helps me the most when I have flu symptoms and muscle pain, the ingredients are similar to any medicine that contains acetaminophen, the savor is good, it is very effective and the cost of the product seems very good to me
5 out of 5 stars
1 October, 2025
originally posted on influenster.com

Great for the money
The ingredients are normal, there isn't a scent, the packaging was eye-catching, and for the price, it is very effective would buy again. It helped a lot
5 out of 5 stars
14 September, 2025
originally posted on influenster.com

works
saved my life many a times in college. the pills are large but shouldn’t be too hard to swallow since they’re gel. easy enough to pop out of the metal tabs
4 out of 5 stars
13 September, 2025
originally posted on influenster.com

I feel the daytime works better than the night tim
I feel the daytime pill works really well. When I have to go into work sick I normally will take a dose of of the daytime. The nighttime I’m 50/50 on. Sometimes I feel it works and other times I don’t think it does. They are easy to take and don’t cost a whole lot.
5 out of 5 stars
26 August, 2025
originally posted on influenster.com

Convenient GoTo
This is my go to for winter colds and flu. I’m always so grateful that I can find it. Usually feel better within a day. It’s convenient to have both day and night in the same package.
5 out of 5 stars
20 August, 2025
originally posted on influenster.com

Effective
Packaging makes it easy to find. I find it works well for cold or flu as I can't have nsaids. It has a bit of a taste when you take them, but it's much better than the liquid taste. Smells are kind of sweet to me. And you get a decent amount of them in a box.
4 out of 5 stars
13 August, 2025
originally posted on influenster.com

Just ok
It works for relieving some of the symptoms when you’re sick and helps you sleep but has so many ingredients I don’t think some even need to be there and it helps my cold symptoms but also gives me a stomach ache and diarrhea
5 out of 5 stars
12 August, 2025
originally posted on influenster.com

It works
Excellent product that is effective and easy to take. It has your standard known ingredients and offers a good value for the money. Safe packaging with easy to read instructions.
5 out of 5 stars
17 July, 2025
originally posted on influenster.com

Great cold and flu medicine
Packaging makes it easy to find. I find it works well for cold or flu as I cant have nsaids. It has a bit of a taste when you take them but it's much better than the liquids taste. Smells kind of sweet to me. And you get a decent amount of them in a box.