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Diphenhydramine Sleep Aid Liquid - Berry - 2pk/12 fl oz - up&up™ - 2 of 3Diphenhydramine Sleep Aid Liquid - Berry - 2pk/12 fl oz - up&up™ - 3 of 3
Diphenhydramine Sleep Aid Liquid - Berry - 2pk/12 fl oz - up&up™ - 1 of 3

Diphenhydramine Sleep Aid Liquid - Berry - 2pk/12 fl oz - up&up™

$12.29

In Stock

Eligible for registries and wish lists

At a glance

About this item

Highlights

  • 2pk diphenhydramine nighttime sleep aid liquid
  • Berry flavored
  • Includes two 12oz bottles
  • Non-habit forming, contains 10% alcohol
  • Uses for the relief of occasional sleeplessness
  • Not for treating cold or flu

Description

Get relief for occasional sleeplessness with this 2-Pack Diphenhydramine Sleep Aid Liquid from up&up™. This twin pack includes two bottles with 12 ounces of diphenhydramine that reduces the time needed to fall asleep. Infused with berry flavor, the soothing nighttime sleep aid is non-habit forming and is not designed for treating cold or flu symptoms.

up&up™: We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Trial/Mini/Travel Size: Yes
Suggested Age: 12 Years and Up
Active Ingredient Strength Value: 50 Milligrams
Product Warning: Consult a doctor if you have glaucoma, consult a doctor if you have a breathing problem
Product Form: Liquid
Primary Active Ingredient: Diphenhydramine
Package Quantity: 2
Net weight: 24 fl oz (US)
TCIN: 87392327
UPC: 311673285022
Item Number (DPCI): 094-01-0155
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

diphenhydramine hcl' '50.0mg

Purpose

Nighttime sleep-aid

Uses

Uses for the relief of occasional sleeplessness reduces time to fall asleep if you have difficulty falling asleep

Directions

Directions take only one dose (30 mL) per day (24 hours) only use the dose cup provided adults & children 12 yrs & over 30 mL at bedtime if needed or as directed by a doctor children under 12 yrs do not use

Other information

Other information each 30 mL dose cup contains: sodium 23 mg store at no greater than 25℃

Inactive ingredients

anhydrous citric acid, fd&c blue no. 1, fd&c red no. 40, flavor, glycerin, propylene glycol, purified water, sodium benzoate, sodium citrate, sorbitol solution, sucralose, sucrose, xanthan gum

Shipping details

Estimated ship dimensions: 2.06 inches length x 5.31 inches width x 7.43 inches height
Estimated ship weight: 1.91 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Additional product information and recommendations

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Frequently bought together

4.1 out of 5 stars with 69 reviews
quality: 2.5 out of 5
value: 2.9 out of 5
27% would recommend
11 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
4 April, 2026Verified purchase

(no review title)

This product is just as good as ZZ Quill
Steve
quality: 5 out of 5
value: 5 out of 5
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4 out of 5 stars
30 January, 2026Verified purchase

It Works

My favorite is still Ambien, because it knocks me out within 20-30 minutes. This knocks me out in an hour. The taste is tolerable; at least it doesn’t taste like NyQuil cold syrups, which make me gag, even when I hold my nose. I stay asleep with this.
Tony
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1 out of 5 stars
Thumbs down graphic, would not recommend
29 January, 2026

Innacurate info

Label online shows 10% alcohol, yet the bottle I got is alcohol free. NyQuil knocks me out because of the alcohol most likely…which was why I decided to try this. Product info needs to be accurately updated. I’ll be returning because it’s no different than taking to generic Benadryl pills now.
Boxermom
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1 out of 5 stars
24 January, 2026Verified purchase

(no review title)

Product was different then what was delivered
Kevin
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5 out of 5 stars
Thumbs up graphic, would recommend
7 January, 2026Verified purchase

Sleep aid at target

Great product and price along with Great customer service by the staff at target.
Josh
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
1 out of 5 stars
Thumbs down graphic, would not recommend
2 December, 2025

Don't buy it!!

It tastes SO BAD
anonymous
quality: 1 out of 5
value: 1 out of 5
2 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
25 August, 2025Verified purchase

Too Sweet

Way too sugary. Too sweet. Nasty.
TJ
quality: 1 out of 5
value: 1 out of 5
1 guest found this review helpful. Did you?
2 out of 5 stars
Thumbs down graphic, would not recommend
27 April, 2025Verified purchase

Tastes NASTY

Pro: it works Con: IT TASTES HORRIBLE. What in the world did you do to the flavoring???? You used to have a nice Cherry Vanilla but that's been gone a long time. The last berry flavor was pleasant. This is vile but I have to use it to get to sleep. I won't be buying this again once I get through the two bottles.
BB
quality: 1 out of 5
value: 3 out of 5
3 guests found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
21 March, 2025Verified purchase

Sleep-Aid

I have trouble going to sleep and these things help and are affordable. Always my go-to sleep aid!
Kindful
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
6 January, 2025Verified purchase

Canceled in recent drive-up order

I placed an order for this two pack, and it was canceled. The single bottles were in stock but they cost more, so they didn't just make the substitution. I guess I'll be buying this in the physical store or find an alternative product elsewhere.
A bit peeved
Did you find this review helpful?
1 out of 5 stars
Thumbs down graphic, would not recommend
16 December, 2024

Got the ick.

Agree with the others…the new flavor/mixture tastes awful and doesn’t seem to work as well as the previous version.
WaffleFry Guy
value: 1 out of 5
quality: 1 out of 5
3 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
11 December, 2024Verified purchase

Different formula, why??🤷♀️

This brand is not the same formula. It says there is 10%alcohol. The 1 I received says alcohol free. What happened?
Jennifer MF
6 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
21 November, 2024Verified purchase

New formula, won't repurchase

New formula (had old bottle to compare) has awful new taste & gives me bizarre, horrific, vivid nightmares anytime I use it. Can’t wait until it’s gone! Only kept this because I bought the double pack & didn’t try it until on a 2.5-wk hurricane deployment with no nearby Target I could run to for return. One star only because it does knock me out. Very disappointed because I’ve been buying this nearly 3-yrs & other sleep aids or melatonin are too strong or have similar issues as this new formula.
HomegrownGal
value: 1 out of 5
quality: 1 out of 5
6 guests found this review helpful. Did you?
2 out of 5 stars
Thumbs down graphic, would not recommend
26 October, 2024

Bad new taste

Flavor has changed and I do not care for the taste. Plus with the price increase, it’s not worth buying this brand anymore. Definitely will be buying NyQuil from now on.
Kelly
quality: 2 out of 5
value: 2 out of 5
4 guests found this review helpful. Did you?
4 out of 5 stars
10 July, 2024Verified purchase

Ehhhh

The price is good, but to me it’s not as strong as the name brand, so doesn’t work as quickly.
Samie2580
value: 5 out of 5
quality: 3 out of 5
4 guests found this review helpful. Did you?

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