Acetaminophen Sinus Pressure, Pain & Cough Relief Caplets - 20ct - up&up™
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$7.39
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$1.59 - $7.99
$15 Target GiftCard with $50 household items purchase
4.7 out of 5 stars with 10638 ratings
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Guests are saying
This sinus pressure and cough medication has garnered mixed feedback from guests. Many appreciate its effectiveness in relieving sinus pressure, headaches, and coughs, often noting its affordability compared to name brands. However, some guests experienced side effects like heartburn and found it less effective for their symptoms. Overall, it serves as a reliable option for those seeking relief during cold and flu season, especially for guests looking to save money without compromising on quality.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.5 out of 5 stars with 532 reviews
quality: 4.19 out of 5
value: 4.31 out of 5
73% would recommend
45 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
7 March, 2026Verified purchase
Excellent!
This is the best medicine! I tried other products in the past and so glad I found this. It worked perfectly! I got relief quickly and had finally kicked my cold that causes sinus problems.
5 out of 5 stars
Thumbs up graphic, would recommend
12 January, 2026
Pretty good!
Needed something fast and CHEAP! i got runny nose, started sneezing, so congested and weird chest feeling all within a couple hours so i got this! There's an up&up with expectorant(for runny nose) but i settled for this without the expectorant and it worked fast! eased my nose up within 20/30 mins anyways and calmed me in general. Made it easier to breathe. Worth it.
1 out of 5 stars
20 December, 2025Verified purchase
(no review title)
Not worth buying. Didn’t help at all
1 out of 5 stars
Thumbs down graphic, would not recommend
30 October, 2025Verified purchase
doesnt work
didn't know a medicine could make me feel worse?? took it 2 days in a row, and everytime 1-2 hours after taking it i felt worse, more congestion and a deeper cough. did nothing, doesn't work, and not a dupe
5 out of 5 stars
Thumbs up graphic, would recommend
16 June, 2025Verified purchase
Up&Up brand for the win!
Great product! It works the same as the name-brand product, but at a better price!
4 out of 5 stars
Thumbs up graphic, would recommend
1 June, 2025Verified purchase
Affordable option
Fast acting but not long lasting relief
5 out of 5 stars
Thumbs up graphic, would recommend
25 February, 2025Verified purchase
The best for sinus infections
This is the only medicine I can truly rely on when coming down with a sinus infection. It alleviates all symptoms, and when taken consistently, prevents the cold from progressing. I always keep this medicing stocked in my cabinet. Better than the namebrand honestly.
1 out of 5 stars
Thumbs down graphic, would not recommend
15 December, 2024Verified purchase
Brain FOG
The brain fog side effects are unreal. Didn’t help too much with congestion either. If you tend to experience side effects with strong cold meds, I would not recommend this.
5 out of 5 stars
Thumbs up graphic, would recommend
20 October, 2024Verified purchase
Thankful
Great relief for sinus problems!
1 out of 5 stars
Thumbs down graphic, would not recommend
5 October, 2024Verified purchase
ADR
Did not work for me. Will not purchase again.
5 out of 5 stars
Thumbs up graphic, would recommend
31 August, 2024Verified purchase
Effective Cold/Flu Medication at Half the Price
I recently tried this Up & Up Maximum Strength Sinus Pressure, Pain, and Cough medication, and I’m thoroughly impressed. It’s a generic version that costs half the price of the name-brand options, yet it works just as effectively. The combination of ingredients provides fast relief from headaches, sinus pressure, and congestion, while also controlling cough and thinning mucus. I was skeptical at first, given the price difference, but this product delivered the same results as the more expensive brands. It’s a great option if you’re looking to save money without sacrificing quality. Highly recommend keeping this on hand for the cold and flu season!
2 out of 5 stars
Thumbs down graphic, would not recommend
10 August, 2024Verified purchase
Severe heartburn
For whatever reason after taking this it gave me severe heartburn. I do have to say it worked for just a tad bit and then along came the heartburn and I was in worse shape than I already was in. If you get bad heartburn, I don’t recommend taking this. The next day I took a Clairtin and it worked so much better.
5 out of 5 stars
Thumbs up graphic, would recommend
1 July, 2024Verified purchase
Up and Up win
Sinus Pressure and cough went away quickly and I felt so much better and for half the price of the other medications.
2 out of 5 stars
Thumbs down graphic, would not recommend
25 May, 2024Verified purchase
Doesn't do much
Got this combo pill because the Target brand Sinus PE, which is just the decongestant phenylephribe, was out. Works on symptoms very minimally. I have better results from getting individual full doses of Sinus PE, Mucus Relief DM, and Tylenol.
1 out of 5 stars
Thumbs down graphic, would not recommend
5 April, 2024Verified purchase
Don't waste your money
It absolutely did NOTHING for me. I had a very bad sinus and head congestion, and after taking this I felt even worse.
1 out of 5 stars
Thumbs down graphic, would not recommend
29 March, 2024Verified purchase
Useless
Doesn't work spend the money on Mucinex
5 out of 5 stars
Thumbs up graphic, would recommend
28 March, 2024Verified purchase
Great
Worked really well for my husband when he had a sinus infection.
5 out of 5 stars
11 March, 2024Verified purchase
Pain relief
I love using Tylenol
5 out of 5 stars
Thumbs up graphic, would recommend
18 February, 2024Verified purchase
Helpful Product
This medicine is always helpful in the moment will sinus issues happen, but for me it proves to be preventative to hopefully help stop further bronchial infections from happening
5 out of 5 stars
Thumbs up graphic, would recommend
30 January, 2024Verified purchase
Great for migraines that are sinus related
One of the only OTC medications that helps with my migraines due to sinus pressure.