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Seed Daily Synbiotic Probiotic Capsules - 60ct - 2 of 4Seed Daily Synbiotic Probiotic Capsules - 60ct - 3 of 4Seed Daily Synbiotic Probiotic Capsules - 60ct - 4 of 4
Seed Daily Synbiotic Probiotic Capsules - 60ct - 1 of 4

Seed Daily Synbiotic Probiotic Capsules - 60ct

$59.99

In Stock

Eligible for registries and wish lists

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About this item

Highlights

  • Clinically validated probiotic and prebiotic formulated with 24 strains not commonly found in foods like yogurt for whole body benefits.*
  • 60 vegan capsules (30 day supply). Take 2 capsules daily, with or without food. No refrigeration necessary. 53.6 billion AFU.
  • Formulated to relieve occasional digestive discomforts like gas, bloating, and constipation, support healthy regularity, and promote healthy gut function after two (2) weeks.*
  • Supports whole body benefits including, digestive, gut, skin, heart, and immune health, as well as gut barrier integrity, and overall microbiome support.*
  • Proprietary ViaCap® technology safeguards probiotics through digestion for superior survivability and precision release to the colon.
  • Concentrated from Indian pomegranate, the novel, non-fermenting prebiotic is clinically validated to produce beneficial metabolites in the gut and improve skin clarity.*
  • Rigorously tested for potency, purity, and contaminants, including all major heavy metals, 500 pesticides, and 20+ common allergens.
  • *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease."

Description

You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. The gut microbiome is connected to various organ systems and pathways throughout the body that are crucial for your health. In a healthy state, the gut microbiome carries out a multitude of functions like regulating digestion, enhancing nutrient absorption, and strengthening immune responses.

Seed’s flagship DS-01® Daily Synbiotic is a probiotic and prebiotic developed for whole body health. Grounded in science, with a deep understanding of the complex interactions within the microbiome—DS-01® is clinically validated for benefits in and beyond the gut including, digestive health, gut health, skin health, heart health, immune health, gut barrier integrity, and overall microbiome support.*

DS-01® is formulated with 24 research-backed probiotic strains that are not commonly found in foods like yogurt, most supplements, or fermented foods and beverages, and a novel, non-fermenting prebiotic concentrated from pomegranate.

But it’s important to remember probiotics are most effective when they arrive at the colon alive. DS-01®’s capsule-in-capsule technology is intentionally engineered to safeguard probiotics through digestion, promoting survivability from stomach acid, digestive enzymes, moisture, and heat, all with no synthetic or chemical coating and no refrigeration required.

Rigorously tested by third parties for potency, purity, contaminants, and several classes of allergens, with 50+ quality assurance and quality control checkpoints, Seed monitors purity under both US and European protocols. The final product is rigorously tested for all major heavy metals, 500 different pesticides (including glyphosate), and over 20 common allergens, as defined by the European Food and Safety Authority (EFSA).

Each jar contains 60 vegan capsules, providing a 30-day supply of 53.6 billion AFU per dose with no refrigeration required.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease."
Contains: Does Not Contain Any of the 9 Major Allergens
Suggested Age: 18 Years and Up
Product Warning: Consult a doctor if you are pregnant or nursing, keep out of reach of children
Product Form: Capsule
Package Quantity: 60
Colony forming units (billions): 0
Active fluorescent units (billions): 53.6
TCIN: 91816039
UPC: 860340001620
Item Number (DPCI): 094-02-5724
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Amount Amount Per Serving:

% Daily Value*
Digestive Health Probiotic Blend 206mg
Micronutrient Synthesis Probiotic Blend 46mg
Dermatological Health Probiotic Blend 37mg
Cardiovascular Health Probiotic Blend 18mg
MAPP Microbiota-Accessible Polyphenolic Precursors 400mg
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

acid-resistant vegan outer [chlorophyllin] and inner [hypromellose, water] capsules, organic rice fiber, organic rice extract blend.

Allergens & Warnings:

If you are attempting to become, or are pregnant or nursing, consult your healthcare provider before use. Keep out of reach of children. Do not use if seal is broken.

Shipping details

Estimated ship dimensions: 2.81 inches length x 2.83 inches width x 3.7 inches height
Estimated ship weight: 0.53 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Q: Hard to swallow? I have problems with large caps and these look large.

submitted by Nansky - 1 year ago
  • A: Yes this is a big concern for me too hope you will show size of pill.

    submitted bystoragelessshopper - 5 months ago
  • A: I only swallow with food and these are not bad. Pretty standard size.

    submitted byFmz - 11 months ago
  • A: Thanks so much for your question! Our DS-01® Daily Synbiotic capsule is size 00—that’s 0.917 inches long with a diameter of 0.322 inches, to be exact. We wouldn't recommend opening or tampering with the DS-01® Daily Synbiotic capsules in any way, as our ViaCap® is especially designed to ensure the bacteria stay alive through digestion and make it to the colon. That said, you may certainly try experimenting with how you may be able to tolerate the capsules—any method in which you can preserve the 2-in-1 ViaCap® capsule would be perfectly fine. Please reach out to care@seed.com with any additional questions!

    submitted bySeed Team - 1 year ago
    Brand expert

Q: is it possible for men to pop this pill?

submitted by Ktwo - 9 months ago
  • A: What are you talking about a man a blogger turned everybody on to this

    submitted byLinda - 7 months ago
  • A: Thanks so much for reaching out! DS-01® Daily Synbiotic is a 2-in-1 probiotic and prebiotic, formulated for adults ages 18+. The DS-01® formula contains 24 clinically and scientifically studied probiotic strains and a polyphenol-based prebiotic, for benefits in and beyond the gut. The probiotic strains in the DS-01® formula have been backed by 16 strain-specific, published human studies as well as 13 in vitro/ex vivo mechanistic studies to indicate benefits for gastrointestinal function, gut barrier integrity, cardiovascular health, gut immune function, micronutrient synthesis, and dermatological health.

    submitted bySeed Team - 9 months ago
    Brand expert

Q: I see you take 2 capsules a day, but what is the best way to take them? With food? Without food? AM/PM? With water or juice? Thanks!

submitted by AigeP - 1 year ago
  • A: You didn't read the directions it says the first three days take one and after that start taking two to see if your stomach in the a.m. and you don't have to have food on your stomach. You can take it with whatever you want to drink it with

    submitted byLinda - 7 months ago
  • A: Thank you for your question! The daily dosage for DS-01® is 2 capsules per day. We suggest taking the capsules on an empty stomach to limit exposure to digestive enzymes and bile salts, but if it’s more comfortable for you to take DS-01® before/after a meal or alongside food, we encourage you to choose the best method for you. Taking the capsules with water or juice is also absolutely fine. There is no best time of day to take them— we recommend whatever fits best into your routine!

    submitted bySeed Team - 1 year ago
    Brand expert

Q: I haven't noticed anywhere on the packaging in store, nor in the product description here if the probiotic's potency is the same at expiration as at the time of manufacture. Is this the case?

submitted by Roseanne - 13 days ago
  • A: Great question! The shelf life of our products is based on testing to validate potency from manufacturing through to end of shelf-life—meaning we ensure the labeled potency of DS-01® is guaranteed through to expiry, not just at the time of manufacturing. If you’d like to learn more about our testing and quality standards, you can learn more at seed.com/reference/syn-wk 🌱

    submitted bySeed Team - 11 days ago
    Brand expert

Q: Is this ok to take if you are taking statins for cholesterol?

submitted by Alida - 4 months ago
  • A: Hi there—great question! There are no known contraindications between probiotics and medications; therefore, DS-01® Daily Synbiotic would be generally safe to take alongside prescription or over-the-counter medication(s). For some additional background (which may be helpful to discuss with your doctor) there may be some potential interactions of pomegranate (mostly in juice form) and certain medications such as statins. For context, statins are metabolized by an enzyme called cytochrome P450 3A4 (CYP3A4). One review [1] shows that pomegranate juice may affect CYP3A4-mediated drugs. However, one study [2] found that pomegranate juice did not seem to have clinically relevant inhibitory potential on CYP3A4 activity, specifically looking at simvastatin. Ultimately, we always recommend consulting with a prescribing physician about combining DS-01® and any medications you may be taking, as they can provide personalized guidance based on your full health history and the specific medications. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10003857/ [2] https://pubmed.ncbi.nlm.nih.gov/25720525/

    submitted bySeed Team - 4 months ago
    Brand expert

Q: I bought one bottle from target but when I opened it there’s two kind of pills not capsules. One big colored white and one small colored pink. Why and what I have to do?

submitted by Not capsules - 5 months ago
  • A: We sincerely apologize for this experience! A member of our Care team has followed up in an email to provide additional support. Warmly, Seed

    submitted bySeed Team - 5 months ago
    Brand expert

Q: Does this come with the glass jar and travel vial ?

submitted by T8lord - 5 months ago
  • A: Thanks for reaching out with this question! All DS-01® Daily Synbiotic purchases made via Target will contain our signature storage jar. Currently, our glass travel vials are exclusively reserved for members at Seed.com 🌱

    submitted bySeed Team - 5 months ago
    Brand expert

Q: Will this product aid in weight loss ?

submitted by Meliss - 5 months ago
  • A: DS-01® Daily Synbiotic has not been studied for its effects on weight specifically; therefore, we are unable to comment on any difference in effect in this regard. This in mind, DS-01® is formulated to provide support for digestive and systemic health with core benefits across gastrointestinal function, gut barrier integrity, immune health, cardiovascular health, micronutrient synthesis, and dermatological health.

    submitted bySeed Team - 5 months ago
    Brand expert

Q: Is it safe to take during pregnancy?

submitted by prolife - 6 months ago

Q: Are these safe for people with shellfish allergies

submitted by Kooka - 7 months ago
  • A: Seed conducts comprehensive allergen testing on all of our products. Our allergen panel includes over 20 of the most common allergens, including all 14 classes of allergens as defined by the European Food and Safety Authority (EFSA). This panel extends well beyond the minimum 8 allergens required to test by the FDA. However, it’s important to note that the FDA has established no clear guidelines for what it means to be “free” of allergens." Therefore, for maximal transparency and integrity, Seed conducts this testing on all of our products and ensures any substance present in our products is at a level below an established reference dose––the Eliciting Dose, or ED-01, which is grounded in clinical evidence and is considered the most precise method for assessing allergenicity. The ED-01 is the eliciting dose required to produce an objective [allergic] response in 1% of the allergic population. All allergens we test for are below the ED-01, so our probiotics are therefore considered to be safe for those with allergies to the tested-for allergens. The following allergens are tested for in all of our consumer products— -Almond Allergen -Brazil Nut Allergen -Cashew Allergen -Celery Allergen -Corn Allergen -Gluten Allergen [across barley, rye, oats + wheat] (wheat protein) -Crustacean Allergen -Egg Allergen -Fish Allergen -Hazelnut Allergen -Lupin Allergen -Macadamia Nut Allergen -Milk Allergen -Molluscs Allergen -Mustard Allergen -Peanut Allergen -Pecan Allergen -Pistachio Allergen -Sesame Allergen -Soy Allergen -Sulfite Dioxide -Walnut Allergen That said, we always encourage folks who are concerned about allergies or sensitivities to consult with a primary care provider.

    submitted bySeed Team - 7 months ago
    Brand expert

Related Categories

3.9 out of 5 stars with 113 reviews
67% would recommend
40 recommendations

Not sure it works. Product

1 out of 5 stars
Julie K. - 18 days ago
originally posted on seed.com
Not sure it works. Product frequently arrives crushed.
Did you find this review helpful?

Microbiome Restored 🤗💩

5 out of 5 stars
Thumbs up graphic, would recommend
Shirley - 22 days ago, Verified purchaser
This is an amazing product. It has restored my bowel regularity. I have tried others but they never made a difference.
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

Let me down

2 out of 5 stars
Thumbs down graphic, would not recommend
Marilyn - 29 days ago
the medicine has variable potency or inconsistent concentration. This means that from one pill, vial, or batch to the next, the amount of active ingredient must changes. I say this because when I bought my 1st jar it worked great I had a BM every day and I was so excited since I usually go once a month. 2nd carded not do the same. 3rd worked again then 4th didn't. I explained this to Seed Co. and cancelled my subscription. They said sorry to hear this. lol . Seriously?
1 reply from Seed Team team - 27 days ago
We’re so sorry to hear about your experience, and we truly understand how frustrating that must feel. We want to reassure you that every batch of DS-01® undergoes rigorous quality control and third-party testing to ensure consistency in potency, purity, and concentration. That said, because the microbiome is dynamic and influenced by many factors (diet, stress, sleep, environment), individual responses can sometimes vary over time—even when the formulation itself is consistent. We never want you to feel dismissed, and we’d love the chance to better support you. If you’re open to it, please reach out to us directly at care@seed.com or via DM so our Care Team can take a closer look at your experience.
quality: 1 out of 5
value: 1 out of 5
1 guest found this review helpful. Did you?

Not for everyone

1 out of 5 stars
Thumbs down graphic, would not recommend
Erica - 1 month ago, Verified purchaser
Can’t get ride of the bloating since I started Seed. Always had a flat stomach and now I feel bloated all the time. Other probiotics never did this to me.
1 reply from Seed Team team - 27 days ago
We’re really sorry to hear about your experience—your comfort matters to us 🌱. For some, changes like bloating can happen in the early days of introducing new probiotic strains, as the microbiome is adjusting. This is typically temporary, but everyone’s body is unique, and we never want you to feel unsupported. If you’d like, please reach out to us at care@seed.com or via DM so our Care Team can learn more and provide personalized support. We’re here to help you feel confident in your experience with Seed.
quality: 5 out of 5
value: 1 out of 5
1 guest found this review helpful. Did you?

Nauseous

3 out of 5 stars
Thumbs down graphic, would not recommend
J - 2 months ago, Verified purchaser
I think it works.. but it makes me nauseous everytime.
1 reply from Seed Team team - 1 month ago
Hi there—we’re sorry to hear about the stomach discomfort with DS-01®! Mild GI symptoms like bloating or changes in stool can be normal in the first few weeks as your body adjusts to a new probiotic. Many members find that starting with 1 capsule per day, then gradually increasing to 2, can ease this transition. You might also try taking DS-01® at a different time of day or closer to food. If any symptoms feel concerning, we always recommend checking in with your healthcare provider. Let us know if you have any questions—we’re here to help!
quality: 5 out of 5
value: 5 out of 5
3 guests found this review helpful. Did you?

Seed

5 out of 5 stars
Thumbs up graphic, would recommend
Kimberly - 2 months ago, Verified purchaser
This prebiotic/probiotic works just like they say it does! I'm thankful for this company creating the Seed product to help all of us have a healthier gut biome.
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?

Helped my gut—still waiting on other benefits

3 out of 5 stars
Thumbs up graphic, would recommend
CD - 3 months ago, Verified purchaser
These definitely take time to kick in, but I did notice a steady improvement in my gut health after consistent use. Less bloating, better digestion, and overall more regular. As for skin or other health benefits, I haven’t noticed a huge difference yet—but I’m still hopeful with continued use. It’s on the pricier side, but the quality feels high and I appreciate the clean ingredients.
quality: 5 out of 5
value: 3 out of 5
3 guests found this review helpful. Did you?

Life changing for IBS-D

5 out of 5 stars
Thumbs up graphic, would recommend
wxgal22 - 3 months ago
Amazing for IBS-D. This probiotic has changed my life. Within a week I noticed a major difference. Stress and foods no longer trigger my IBS.
quality: 5 out of 5
value: 5 out of 5
11 guests found this review helpful. Did you?

A Keeper

5 out of 5 stars
Thumbs up graphic, would recommend
Favorite - 3 months ago, Verified purchaser
This supplement works amazingly well - even with a single pill the first few days, I’m really surprised. Will continue with it and recommend as well.
quality: 5 out of 5
value: 4 out of 5
6 guests found this review helpful. Did you?

Waste of money

1 out of 5 stars
Thumbs down graphic, would not recommend
Wa - 3 months ago, Verified purchaser
It advertised working for constipation. This product does not work for constipation & very expensive. Don’t waste your money.
1 reply from Seed Team team - 3 months ago
Hi there—thank you for taking the time to share your experience with DS-01®. We’re genuinely sorry to hear that the product didn’t meet your expectations for constipation support. Every individual’s gut microbiome is unique, which means the timeline—and type—of benefits felt can vary widely. For some, digestive shifts like improved regularity or less bloating can occur early on. For others, it may take a few weeks or longer as the body adjusts to the introduction of potent, clinically studied strains. It’s also worth noting that while visible digestive changes are often the most noticeable, DS-01® works in ways that may not always be felt right away. The strains in DS-01® have been studied to support immune function, gut barrier integrity, and even the production of key nutrients like folate and B12—important work that happens “behind the scenes” to support systemic health. That said, we know how important it is to feel supported by the products you use, and we appreciate you giving DS-01® a try. If you’d like help reviewing your experience or exploring next steps, our team is always here to support you.
quality: 1 out of 5
value: 1 out of 5
2 guests found this review helpful. Did you?

Seed DS 01

5 out of 5 stars
Thumbs up graphic, would recommend
Gut Help - 4 months ago, Verified purchaser
I was told by my Medicare provider Blue Flex payment card is honored at Target. Not true. Product is Great!
1 reply from Seed Team team - 3 months ago
Thank you so much for your kind words about the product—we’re thrilled to hear it’s been a great fit for you! We're sorry for the confusion regarding payment methods at retail. While we don’t have insight into individual store policies or specific insurance or benefits cards (like Blue Flex), we recommend checking directly with the retailer to confirm eligible payment methods before purchase. If you ever decide to order directly from Seed.com, we’re always here to help with any questions or support you may need. Warmly, Seed Health, Inc.
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

It hasn’t helped me at

1 out of 5 stars
Bettie H. - 4 months ago
originally posted on seed.com
It hasn’t helped me at all. How long should it take?
Did you find this review helpful?

Dont even think about it

1 out of 5 stars
Thumbs down graphic, would not recommend
sick - 4 months ago
Expensive laxative- you will be crippled over in pain every day you take this. Reviews posted here must be fake and reposted from the website where they were fraudulently written. Avoid at all costs.
1 reply from Seed Team team - 4 months ago
We’re so sorry to hear about your experience and appreciate you taking the time to share it. What you’ve described is not the experience we hope for any member of our community, and we understand how frustrating this must feel. Because each individual’s microbiome is unique, responses to DS-01® can vary. While some members notice benefits like improved digestion or ease of bloating early on, others may experience temporary discomfort—especially in the first few days—as their body adjusts to the potent strains in our clinically studied formulation. That said, if the effects ever feel more than mild or manageable, we always recommend checking in with a healthcare provider to ensure DS-01® is the right fit for your system. We also want to assure you that every review on our site is submitted by verified buyers—we’re committed to transparency and to holding space for both positive and challenging experiences as we continue to learn from our members. If you’d like to discuss your experience further or have questions about the science behind DS-01®, our SciCare team of experts is always available at scicare@seed.com. Wishing you comfort and clarity on your health journey.
quality: 1 out of 5
value: 1 out of 5
3 guests found this review helpful. Did you?

This product makes my mornings

5 out of 5 stars
Lisa M. - 5 months ago
originally posted on seed.com
This product makes my mornings drama free, smooth and easy and less bloating.
Did you find this review helpful?

Happy right away 30 minutes after first dose

5 out of 5 stars
Thumbs up graphic, would recommend
Instoreshopperjune2025 - 5 months ago
Had trouble sleeping. I took my first pill and felt awake and overjoyed within 30-45 minutes. I'm excited to start this journey. With seed. Being a daily fruit and fish eater with limited dairy I feel effects pretty fast knowing if it's a good fit or not. Take one pill with the first 3 days. If this grace period is okay (no bad side effects increase your dose to two pills twice a day two in the am 30 minutes before your first meal.
quality: 4 out of 5
value: 5 out of 5
Did you find this review helpful?

Try This

5 out of 5 stars
Thumbs up graphic, would recommend
Kevin - 5 months ago, Verified purchaser
On my 3rd bottle. I havent had an upset stomach or bloat in months.
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?

CHANGED MY LIFE!!

5 out of 5 stars
Thumbs up graphic, would recommend
summerdazedean - 5 months ago
I’ve struggled with going to the restroom my whole life. Used to only go once every 4 days. This regulating me within 24 hours. I now go every single day and it’s the healthiest it’s ever been. Sorry for TMI but please buy this if you’re on the fence. It will change your life!
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?

Best probiotic EVER

5 out of 5 stars
Thumbs up graphic, would recommend
danivanity - 5 months ago, Verified purchaser
I’m in love with this probiotic. I’ve used Metamucil, miralax, colace - none of it helps with regularity and bloat like Seed.
quality: 5 out of 5
value: 5 out of 5
5 guests found this review helpful. Did you?

This is a great product

5 out of 5 stars
Stacie D. - 6 months ago
originally posted on seed.com
This is a great product that helps my body daily. Within a few weeks I noticed differences.
Did you find this review helpful?

So far, I have been

5 out of 5 stars
Linda N. - 7 months ago
originally posted on seed.com
So far, I have been enjoying my Seed product. I like the reusable jar and refill packets.
Did you find this review helpful?

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