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Systane Hydration Multi-Dose Preservative Free Dry Eye Drops - 0.34oz/2pk - 2 of 4Systane Hydration Multi-Dose Preservative Free Dry Eye Drops - 0.34oz/2pk - 3 of 4Systane Hydration Multi-Dose Preservative Free Dry Eye Drops - 0.34oz/2pk - 4 of 4
Systane Hydration Multi-Dose Preservative Free Dry Eye Drops - 0.34oz/2pk - 1 of 4

Systane Hydration Multi-Dose Preservative Free Dry Eye Drops - 0.34oz/2pk

$26.49 ($38.96/fluid ounce)

In Stock

Eligible for registries and wish lists

About this item

Highlights

  • Experience preservative free dry eye relief that is extra moisturizing for sensitive eyes
  • Exclusive formula not available in store brands
  • Preservative-free relief is perfect for sensitive eyes
  • Advanced hydration

Description

Provides long-lasting hydration and restores moisture to dry eyes with hydro boost technology.
Suggested Age: 2 Years and Up
Health Facts: Preservative-Free
Product Warning: Keep out of reach of children
Product Form: Drops
Primary Active Ingredient: Polyethylene Glycol
Package Quantity: 2
Contact Lens Type: Silicone Hydrogel
Net weight: .68 fl oz (US)
TCIN: 94306593
UPC: 300651510003
Item Number (DPCI): 245-09-0256
Origin: Made in the USA
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

polyethylene glycol 400(0.4%), propylene glycol(0.3%).

Purpose

Lubricant, Lubricant..

When using this product

When using this product : do not touch tip of container to any surface to avoid contamination,replace cap after each use.

Stop use and ask a doctor if you experience any of the following:

Stop use and ask a doctor if you experience any of the following: : eye pain,changes in vision,continued redness or irritation of the eye,condition worsens or persists for more than 72 hours.

Directions

Directions for Use: Hold the bottle just below the cap and twist the cap to open. Before first use, hold the bottle upside down and dispense one drop of product to discard. Shake the bottle downward to remove residual product (see picture). Place 1 or 2 drops in the affected eye(s) as needed and blink. After use, shake the bottle downward to remove residual product that may be left on the tip (see picture above). Replace cap after use. Put 1 or 2 drops in the affected eye(s) as needed. See side of carton for directions for use.

Other information

Store at room temperature.

Inactive ingredients

aminomethyl propanol, boric acid, hydroxypropyl guar, potassium chloride, purified water, sodium borate, sodium chloride, sodium hyaluronate, sorbitol, may contains hydrochloric acid and/or sodium hydroxide to adjust ph

Question or comments?

800-757-9195

Shipping details

Estimated ship dimensions: 4.29 inches length x 2.6 inches width x 1.18 inches height
Estimated ship weight: 0.08 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Additional product information and recommendations

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4.6 out of 5 stars with 233 reviews
quality: 4 out of 5
value: 3.75 out of 5
66% would recommend
6 recommendations
5 out of 5 stars
Thumbs up graphic, would recommend
9 May, 2026Verified purchase

Best eyedrop for soothing and lasting relief. I've tried them all. Systane is my go to.

I have chronic dry eyes and this is the best eyedrop I've found. Provides soothing, lasting relief and you can use as often as you like.
dld1717
quality: 5 out of 5
value: 5 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
20 February, 2026Verified purchase

These work for episcleritis!

I have dry eye induced episceleritis in my left eye. I have tried a majority of drops, gels, and ointments on the market. I eventually ended up on steroids but the long term side effects are horrible, and knew I could only use them short term until I found a solution. Refresh/-cellulose based drops recommended by my opthalmologists were keeping my condition persistently aggravated, and no one had any idea this was the case. As I continued to experiment with drops, I started Systane’s PF hydration drops, and with two weeks of consistent use, my dry eye induced episcleritis finally subsided. This was after 6 months of trial and error with eye drops. Now I only have to use eye drops in the winter or when i use the heater. Give these a try, and make sure when you’re using these, do NOT use any other brand simultaneously. Formulations definitely do react with one another, several combos were making my eyes significantly more irritated. At night, plan to out in these drops just before you are about to sleep - put a couple drops in each eye, and close your eyelids and keep them closed until morning.
X620
quality: 5 out of 5
value: 4 out of 5
Did you find this review helpful?
1 out of 5 stars
Thumbs down graphic, would not recommend
14 February, 2026Verified purchase

Dont buy

Angry! Opened sealed package and one of the two bottles was open and was empty! Can’t return for refund as no proof.
Returning it
quality: 1 out of 5
value: 1 out of 5
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
14 October, 2025

instant hydration for my eyes!

I use Systane Hydration daily. My eyes instantly feel hydrated when I put the drops in.
MAT
quality: 5 out of 5
value: 5 out of 5
1 guest found this review helpful. Did you?
5 out of 5 stars
Thumbs up graphic, would recommend
17 May, 2025Verified purchase

Does the job

Works well if you need a preservative free option. Keeps my eyes hydrated. Helps when inserting and removing hard contact lenses.
Teacher
Did you find this review helpful?
1 out of 5 stars
Thumbs down graphic, would not recommend
15 April, 2025Verified purchase

Poor dropper design

The dropper design is horrible. I had a sample vial and thought the product itself was adequate so I ordered a bottle. It is so difficult to get even a drop out of the bottle, it is a waste of money.
Atkinsgirl
4 guests found this review helpful. Did you?
3 out of 5 stars
8 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Dry eyes

This product is okay. I think it would be better if it was also for red itching eyes
Lucille
Did you find this review helpful?
5 out of 5 stars
7 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Refreshing

These eye drops are great. They felt very refreshing and took any redness or itchiness out of my eyes. I would definitely recommend please eye drops
Heather
Did you find this review helpful?
4 out of 5 stars
7 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Does the job

The product is good but I find myself needing to apply more frequently than other brands purchased in the past.
Natalee
Did you find this review helpful?
4 out of 5 stars
7 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Feels good in my eyes

This product does feel like it soothes and hydrated my eyes! My eyes have a tendency to feel dry and red, and these drops bring a sense of cooling to my eyes. I'm not sure about how they dispense because it's hard to be accurate with them, so that's the only negative I can say about it.
Misty
Did you find this review helpful?
5 out of 5 stars
6 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Works great

This years allergies have been really hard on my eyes. These drops have definitely helped my dry eyes.
Jamie
Did you find this review helpful?
5 out of 5 stars
4 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

HYDRATION Preservative-Free Dry Eye Drop

HYDRATION Preservative-Free Dry Eye Drop effectively relieves dry eyes
Joy
Did you find this review helpful?
5 out of 5 stars
4 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Hydrating!

These systane hydration eye drops are where its at! I had pink eye about 2 weeks ago and have suffered from severe dry eye since, I was waking up and my eyes were literally stuck shut, these drops have saved my eyes! I put drops in before bed and I wake up with just regular dry eyes now!
Nichole
Did you find this review helpful?
5 out of 5 stars
3 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Review for sustained drops

These eye drops work great. My eyes are sensitive to most eye drops I've tried, which often burn and still leave my eyes feeling dry. Systane eye drop actually leave my eyes feeling lubricated without the burn. I will definitely use these from now on.
Hope
Did you find this review helpful?
5 out of 5 stars
2 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Very impressed!!

Out of all of the eye wetting drops I have tried, this one did the trick! I only had to put one drop in both eyes, and they stayed moist for hours! These weren't red eye relief, which would have been the cherry on top, but they definitely did what they were intended to do. So keep in mind, if you're looking for something to get rid of red eyes, this wouldn't be for you, but for all other purposes, I approve! I had something stuck in my eye that, for the life of me, I just couldn't find or remove. I flushed my eye with this and voila! It was instantly relieved. Will definitely purchase in the near future!
Cyndi
Did you find this review helpful?
2 out of 5 stars
2 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Systane Lubricant eye drops

This is an honest review. Used these eye drops and a haze came over my eyes. Will not use them again. I did read the ingredients and saw hydrochloric acid as an ingredient which I have used as a drain cleaner so I stopped using the eye drops.
Mary
Did you find this review helpful?
5 out of 5 stars
1 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Great product

Works great in keeping my eyes hydrated I would definitely recommend it it's easy to use and small enough to carry in your purse or pocket I wouldn't change anything thank you for this opportunity
Veronica L
Did you find this review helpful?
4 out of 5 stars
1 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Eye drops

SYSTANE HYDRATION Preservative-Free Dry Eye Drops have been the the drops I've used most recently and the brand helps with hydrating my dry eyes .
S
Did you find this review helpful?
5 out of 5 stars
1 July, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Systane Hydration PF Eye Drops

I received these eye drops for free for testing and review. They have been wonderful for my severe dry eyes. I suffer from allergies all year long. They last longer than many other eye drops I've tried before. I like that these lubricate, last longer and even gets rid of redness, unlike many other brands I've tried.
Kelly
Did you find this review helpful?
5 out of 5 stars
30 June, 2023
originally posted on https://www.myalcon.com/consumer/
Image

Great for dry eyes

This product was great for dry eyes. My eyes get really dry from allergies and it's hard finding something ther doesn't make them burn more, but this seemed to work and didn't cause any issues
Breanna
Did you find this review helpful?

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