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Diphenhydramine HCl Nighttime Sleep Aid Softgels- 48ct - up&up™ - 2 of 3Diphenhydramine HCl Nighttime Sleep Aid Softgels- 48ct - up&up™ - 3 of 3
Diphenhydramine HCl Nighttime Sleep Aid Softgels- 48ct - up&up™ - 1 of 3

Diphenhydramine HCl Nighttime Sleep Aid Softgels- 48ct - up&up™

$2.79 ($0.06/count) reg $3.99
Clearance save $1.20 (30% off)

In Stock

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At a glance

About this item

Highlights

  • Packaging may vary. Same trusted quality
  • Compare to active ingredient in Vicks ZzzQuil
  • 25mg diphenhydramine softgels are ideal for occasional sleeplessness
  • Sleep aid helps you get to sleep so you can wake up refreshed
  • 24ct package allows you to be prepared whenever insomnia strikes

Description

If you're having trouble getting some shut-eye, try Diphenhydramine HCl Nighttime Sleep Aid Softgels from up&up™. Diphenhydramine HCl is a non-habit forming antihistamine that promotes sleepiness, helping you drift off to dreamland in no time. Whether you're traveling or just having trouble getting to sleep at night, these softgels are an easy, reliable way to get the sleep you need to feel rested.


We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Suggested Age: 12 Years and Up
Health Facts: Contains Diphenhydramine HCl
Active Ingredient Strength Value: 25 Milligrams
Product Warning: Do not use with other drugs that cause drowsiness, not for children under the age of 12, use caution while operating machinery, consult a doctor if you have a breathing problem, consult a doctor if you are pregnant or nursing, use caution while driving a motor vehicle, do not use with other diphenhydramine products, ask a doctor if you have prostate issues, consult a doctor if you have glaucoma, consult a doctor if you have heart disease
Product Form: Softgel
Primary Active Ingredient: Diphenhydramine
Package Quantity: 48
TCIN: 50284885
UPC: 311673703489
Item Number (DPCI): 094-01-0281
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

diphenhydramine hcl' '25.0mg

Purpose

Nighttime sleep-aid

Uses

Uses for the relief of occasional sleeplessness, reduces time to fall asleep if you have dictate falling asleep

Directions

Directions take only one dose per day (24 hours) 2 softgels at bedtime if needed or as directed by a doctor adults & children 12 yrs & over children under 12 yrs do not use

Other information

Other information store at 20-25° C (68-77°F), avoid excessive heat above 40°C (104°F), protect from light

Inactive ingredients

fd&c blue no. 1, fd&c red no. 40, gelatin, polyethylene glycol 400, propylene glycol, purified water, shellac, sorbitol sorbitan solution, titanium dioxide.

Shipping details

Estimated ship dimensions: 1.34 inches length x 3.83 inches width x 5.25 inches height
Estimated ship weight: 0.1 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Additional product information and recommendations

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Guests are saying

This sleep aid has garnered mixed feedback from guests, with many praising its effectiveness in promoting restful sleep without causing drowsiness. Guests appreciate its affordability and non-habit forming nature, making it a suitable option for occasional use. However, concerns about the packaging and some guests experiencing limited effectiveness highlight the need for potential improvements. Overall, it offers a viable solution for those seeking better sleep.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.4 out of 5 stars with 133 reviews
    quality: 3.75 out of 5
    value: 3.75 out of 5
    50% would recommend
    16 recommendations
    5 out of 5 stars
    25 November, 2025Verified purchase

    (no review title)

    Works as good as the over priced version by another maker
    Toby
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    9 September, 2025Verified purchase

    Sleep magic

    Puts me to sleep no issue and never feel drowsy the next day
    Fiona
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    11 August, 2025Verified purchase

    Don't buy, spend the money for name brands

    Doesn't work for me, i lay in bed for hours not to fall asleep. The package for the pills is a pain to deal with too, i feel like when i do fall asleep, im more tired waking up.
    Cassie Mack
    quality: 1 out of 5
    value: 1 out of 5
    3 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    25 December, 2024Verified purchase

    Not worth the capsule packaging fight

    Terrible packaging. Didn't help with sleep issues unfortunately. If you have arthritis in your fingers, don't even bother unless you have someone to help!
    Lk
    1 guest found this review helpful. Did you?
    2 out of 5 stars
    Thumbs down graphic, would not recommend
    18 May, 2024Verified purchase

    Sleepless

    The packaging is ridiculous. Can’t open them without using scissors. Will not buy again
    Tired
    2 guests found this review helpful. Did you?
    4 out of 5 stars
    26 February, 2024Verified purchase

    These work!

    These work and are definitely non-habit-forming! Just use them when you really need them.
    Ashtonh
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    26 September, 2023Verified purchase

    Expired

    I can't believe you didn't check when the product expires, I recieved 3 boxes that expired in July 2023 and another one this month september 2023 I'm so disapoointed !
    Lulu
    quality: 1 out of 5
    value: 1 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    16 September, 2023Verified purchase

    Add to your medicine cabinet!!!

    Works perfect for me. No side affects. Wake up feeling rested. That is my experience. I hope this works for you as well.
    Thatsgirl
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    2 out of 5 stars
    Thumbs down graphic, would not recommend
    30 August, 2023

    Packaging is AWFUL

    The product would be absolutely fine but the packaging for this is awful ! You can’t peel back the tablets from their foil and plastic compartments, and even using scissors to open them is tricky and tedious. If these came in a bottle , I would rate 5 stars - that’s how inconvenient the packaging is.
    catddy
    quality: 3 out of 5
    value: 3 out of 5
    4 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    9 May, 2023Verified purchase

    The best

    Sleep apnea sufferer. This is the only thing that puts me to sleep and allows me to sleep through the night. Waking up can be difficult but as soon as I get out of bed it’s gone. I feel so rested after taking these.
    MamaBear
    value: 5 out of 5
    quality: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    26 April, 2023Verified purchase

    Great Energy Boost/Low Carb

    Great taste and low carb. Also no caffeine crash afterwards
    Lori
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    24 April, 2023Verified purchase

    The same as Zzquil

    Just like my Zzquil knocks me right out for my 5a shifts. Best part is it’s more affordable
    Tina
    quality: 5 out of 5
    value: 4 out of 5
    1 guest found this review helpful. Did you?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    16 February, 2023

    It's literally benadryl.

    No, seriously. It’s the same dose & ingredient in Benadryl. If you REALLY want to save your money, buy the actual thing.
    Amanda
    quality: 3 out of 5
    value: 3 out of 5
    4 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    26 January, 2023Verified purchase

    Half the price of Zzquil - Same results !!

    Finally a full night of sleep!! I love these. They don't make me drowsy at all. No more waking up in the middle of the night being restless! They are also cheaper than Zzquil.
    Cec D
    1 guest found this review helpful. Did you?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    28 December, 2022Verified purchase

    So tired when waking up

    It helps a bit to go to sleep but you wake up soooo tired like if you just went to the gym that’s the downfall
    Emy090595
    quality: 2 out of 5
    value: 3 out of 5
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    17 February, 2021

    Best sleep aid ever!

    I have sleep apnea and have been trying something to put me to sleep for a while. This product is the best sleep aid I have ever tried! I fall into a deep sleep that last until my alarm goes off. Love them! Get these!
    Kasadi
    value: 5 out of 5
    quality: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    1 February, 2021Verified purchase

    zzz

    Works as expected and quickly. I really like that each pill is only 25mg
    Kft
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    7 October, 2020Verified purchase

    As good as the name brand

    I’ve taking ZQuil for a long time and decided to try these ones. The work just as good but at a much cheaper price!
    A Laramee
    quality: 5 out of 5
    value: 5 out of 5
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    19 September, 2020Verified purchase

    Great sleep aid

    I take one of these every night. It helps me to fall asleep faster and stay asleep longer without putting me into too deep of a sleep. I like to be able to wake in the night if necessary! Much cheaper than Zzzquil.
    Mypunkygirl
    value: 5 out of 5
    quality: 5 out of 5
    3 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    6 March, 2020

    Not good

    This is the least effective sleep aid I have ever used. Makes me fall asleep a bit sooner but wears off in about 2 hours and wakes me up right away.
    Chelsean
    Did you find this review helpful?

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