Sudafed PE Day + Night Maximum Strength Sinus Decongestant Tablets - 20ct: Contains Antihistamine, Allergy Treatment
$8.99 ($0.45/count)
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Guests are saying
The product has received mixed feedback from guests regarding its effectiveness in relieving sinus congestion and pressure. While some guests found it helpful, particularly the nighttime version, others reported little to no relief, often preferring the original formula with pseudoephedrine. The convenience of having both daytime and nighttime options is appreciated, but the packaging design has drawn criticism for being difficult to open. Overall, guests suggest considering personal needs when choosing this product.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.4 out of 5 stars with 417 reviews
effectiveness: 2.27 out of 5
quality: 2.53 out of 5
value: 2.53 out of 5
40% would recommend
25 recommendations
5 out of 5 stars
10 March, 2026
originally posted on influenster.com

Easy to open
Easy to swallow and works fast Had no problem with it but I was worried about the safety of the water amount I needed to drink but was very effective
5 out of 5 stars
17 February, 2026
originally posted on influenster.com

Great!
This has to be one of the best meds to take when you have cold. If you have congestive this clears it up within 3 days. Will continue to repurchase this is the future
5 out of 5 stars
29 January, 2026
originally posted on influenster.com

Convenient dual pack!
I appreciate Sudafed PE daytime and nighttime combo pack. The nighttime formula has diphenhydramine (Benadryl) to help dry up the sinus's and sleep easier. The tablets are reasonable to take with no after taste. My go-to med for sinus congestion.
4 out of 5 stars
28 January, 2026
originally posted on influenster.com

Love that it has the day amd night in one box
These have the day and night which is a plus. I still feel like I get a little drowsy on the daytime, not as bad as the nighttime. They are small and easy to take. They seem to last for about 5 or hours so that is also a plus. The night makes it easy to sleep.
5 out of 5 stars
24 December, 2025
originally posted on influenster.com

Convenient day + night relief that helps reduce sinus pressure and makes it easier to breathe and sleep.
I tried SUDAFED PE Sinus Congestion Day + Night during a bad sinus cold and it definitely helped with pressure, stuffiness, and that heavy congested feeling in my head. The daytime pills didn't make me drowsy and allowed me to stay functional, while the nighttime dose helped me breathe easier so I could actually sleep. It's easy to follow the instructions and convenient having both day and night options in one box. It's not a miracle solution, but it made a noticeable difference within a couple of hours and gave me relief when nothing else was helping. I will keep it on hand for future sinus issues.
1 out of 5 stars
Thumbs down graphic, would not recommend
7 November, 2025Verified purchase
didn't work for me
It didn't really help my symptoms.
5 out of 5 stars
21 October, 2025
originally posted on influenster.com

Great affordable buy
I will usually buy different varieties of this product. Another review I stated it works almost immediately. Very cost effective for what reliefs it provides. Is hard to get access to in stores as you will need associate assistance.
1 out of 5 stars
Thumbs down graphic, would not recommend
7 September, 2025Verified purchase
Doesn't work.
Didn't work at all. Actually made me more congested than I already was.
1 out of 5 stars
Thumbs down graphic, would not recommend
26 August, 2025Verified purchase
Does not work! Read the reviews first!
No effect at all. FDA determined the active ingredient does not work when taken orally.
5 out of 5 stars
20 August, 2025
originally posted on influenster.com

best for congestion/sinus pressure
Super effective for congestion and sinus pressure. Great value for daytime and nighttime use. Can find in most stores, my go to when sick for myself as well as the family.
5 out of 5 stars
28 July, 2025
originally posted on influenster.com

Works great and quick
So effective and gets to working quick! The ingredients are great a minimum and the scent actually smells good. It works quick and only need to take once so it's a great value and last a long time! The packaging tells you everything you need to know!
5 out of 5 stars
17 June, 2025
originally posted on influenster.com

Very effective
This is the best sinus congestion medicine i have ever tried, clears up most of the time in the same day! It's a little on the pricier side, but definitely worth every penny!
4 out of 5 stars
1 June, 2025
originally posted on influenster.com

Great product
With the allergies we deal with every year this is by far the best product to clear it out. The value for the relief you're getting is so worth it. Easy to open packaging for on the go too!
1 out of 5 stars
Thumbs down graphic, would not recommend
5 May, 2025
Wrong active drug
I didn’t look closely enough at the ingredients and didn’t realize I was getting sold the Sudafed that doesn’t work. Very annoyed this is still on the market!! Fyi if you are looking for nasal decongestant, don’t buy this one! You are looking for pseudoephedrine not phenylephrine. Don’t buy this!! Wasted my money 😖
1 out of 5 stars
Thumbs down graphic, would not recommend
4 March, 2025
Nothing
I literally noticed no difference. A waste of my time & money
1 out of 5 stars
6 February, 2025
originally posted on sudafed.com
It does not work
Do not buy the over the counter one it contains phenylephrine which is as good as placebo - wais of money & time and prolong suffering. Did NOTHING to releive my symptoms. Have to make another trip to the pharmacy to get the one from the pharmacist that contains pseudoephedrine, hopefully that works.
1 out of 5 stars
Thumbs down graphic, would not recommend
20 January, 2025
Not worth it
This does absolutely nothing. Don’t waste your money
1 out of 5 stars
Thumbs down graphic, would not recommend
10 January, 2025Verified purchase
Get the OTC instead!
Don’t bother with this. You are better off going to the pharmacy counter and purchasing Sudafed there. Sudafed PE doesn’t work.
5 out of 5 stars
Thumbs up graphic, would recommend
29 December, 2024
Control your nasal congestion first, then you won't have a cough
Sudafed helps relieve nasal pressure and congestion so you can breathe easier. Fought two bouts of the cold/flu viruses in October and the end of November into December, both times feeling under the weather for more than two weeks. Took this as suggested and it helped, along with using a Neti pot nasal rinse 5-6x/day. Ensuring you control your congestion in your sinus passage helps prevent post-nasal drip and eventually chest congestion and/or phlegm from producing. Once you lay flat and have all that congestion dripping into your airway and into your lungs, that’s when your nasty cough starts.
4 out of 5 stars
Thumbs up graphic, would recommend
21 November, 2024
Nighttime pills work well.
Nighttime pills seem to work better than daytime, at drying up congestion and stopping sinus pain and pressure.